被曝二世健康影響調査

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1 19 3

2

3 ,000 5mGy 5mGy 24, % 11,951 BMI 1

4 - 1Gy Gy

5 ABCC ICRP 1996 F1 3

6 2. 1 ICRP 10,000 76, Gy 0.005Gy 33, ,824 14,574 39, % 50.6% 51.3% 23,190 14,226 37, % 49.4% 48.7% 48,014 28,800 76, % 100.0% 100.0% 4

7 2. 10,978 6,222 17, % 51.5% 50.9% 10,716 5,870 16, % 48.5% 49.1% 21,694 12,092 33, % 100.0% 100.0% 17, ,040 3,050 10, % 51.4% 57.0% 4,727 2,881 7, % 48.6% 43.0% 11,767 5,931 17, % 100.0% 100.0% ,000 20, Gy DS86 DS86 9,813 1Gy 24,673 16,348 9,238 7, ,151 4,

8 ,540 3,755 3,517 9, ,274 2,692 2,674 7, ,814 6,447 6,191 16, ,911 1,220 4, ,899 1,155 4, ,683 3,810 2,375 8, ,355 5,666 4,737 13, ,142 4,591 3,829 11, ,353 4,497 10,257 8,566 24, Gy No Info Unexposed < >=1.0 Unknown No Info 1, ,961 Gy Unexposed 3,773 3,236 3, ,235 < ,142 1,773 1, , ,012 1,309 1,043 1, ,026 >= Unknown ,181 6,441 6,253 8, ,673 DS ,673 (a)(b) (c)(d)(e) (f) 6

9 2 24, , , % 388 (1.6%) 16, % , % 16,756 (67.9%) 2,611 (10.6%) 14,145 (57.3%) 11,951 (48.4%) 4,805 (19.5%) % % 7,917 7, ,917 7, % (32.1%) (32.1%) (0.0%) (0.0%) (32.1%) 24, % 24,673 10,528 14,145 11,951 12,722 % 24, % 7

10 ,199 (29.2%) 16,756 14, % 11, % 11, ,018 1,684 5, % 42.3% 47.7% 3,955 2,294 6, % 57.7% 52.3% 7,973 3,978 11, % 100.0% 100.0% 10,000 24,673 11,284 13, % 46% 11,951 6,249 5,702 10% 48% 52% PC 8

11

12 % 11, % 43% 55% 48.8% 47.8% , % 14, % 11, 951 ( / )= 48.4 % 43% 55% 9 (1) 3 (%) (2) (3)/(2) (3)/(1) 16,348 9,495 7, ,325 4,650 3, ,673 14,145 11,

13 , , , , , , CT MRI 12 11

14 X , or, or HbA1c6.5 or ( mg/dl) or ( mg/dl), or 220 mg/dl, or or 90 and or 90 and PTCA, or, or etc. and PTCA, or, or etc. and CTMRI, or, etc

15 %96.7% 97 20% , , , , , , , , ,

16 , % 553 (9.7%) 215 (3.4%) 4,622 (38.7%) 2,096 (36.8%) 2,526 (40.4%) 3,152 (26.4%) 1,931 (33.9%) 1,221 (19.5%) 91 (0.8%) 61 (1.1%) 30 (0.5%) 46 (0.4%) 44 (0.8%) 2 (0.0%) 81 (0.7%) 50 (0.9%) 31 (0.5%) 6,530 (54.6%) 3,410 (59.8%) 3,120 (49.9%) 14

17 BMI p (<0.1 ) 4 p

18 GEE) Gy [95]

19 [ ] 0.88 [0.51, 1.52] 2 52~72 23% mGy BMI Gy Gy Gy fractional polynomialslocally weighted regression 17

20 17. Gy , 0.79, , 0.90, , 0.88, , 0.95, 1.07 * 0.80, 0.89, , 0.96, 1.08 *+* 0.80, 0.89, , 0.97, BMI 0.80, 0.90, , 0.99, , 0.90, , 0.98, , 0.91, , 0.98, , 0.90, , 0.98, * 0.81, 0.91, , 0.98, , 0.91, , 0.98, (p = ) p = (95% ) 1.00 (95% ) 18

21 () () OR [95%] log(or) (OR) [95%] log(or) (N=11,951) [0.66, 0.90] [1.09, 1.67] (N=11,951) [0.65, 0.91] [1.09, 1.68] (N=9,779) [0.64, 0.92] [1.01, 1.66] Gy Gy

22

23 Chairman Committee Members Chairman Committee Members 21

24 Chairman Vice-Chairman Committee Members 22

25

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