THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June 2014 azithromycin AZM, 500 mg 37.0 C communityacquired pneumonia; CAP C C-reactive protein; CRP 9
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1 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS azithromycin; AZM 15 community-acquired pneumonia; CAP AZM A-DROP CAP AZM CAP AZM 500 mg 1 1 X AZM AZM 88.5% A-DROP 85.2% 91.2% 91.7% AZM AZM AZM CAP
2 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June 2014 azithromycin AZM, 500 mg 37.0 C communityacquired pneumonia; CAP C C-reactive protein; CRP 9,000/mm 3 X computed tomography CT 5 1 AZM A-DROP 2 AZM H A-DROP AZM AZM 1 AZM 3 AUC mg 2 2 AZM CAP 6 X 4 CRP CAP 30% A-DROP 1 CAP AZM 1 1 AZM AZM AST, ALT BUN, Scr AZM AZM
3 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS AZM % % % % 6 4 AZM A-DROP % % AZM % % AZM A-DROP 23/ % 31/ % 11/ % AZM AZM 7 2 X 7 4 CRP Streptococcus pneumoniae 6 4 Staphylococcus aureus S. pneumoniae 6 4 AZM 1.
4 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June n 61 AZM MIC 2 CLSI 2 4 AZM 4 AZM % % 3 4 AZM AZM 2 AST 8 2 ALT 12 1 BUN 1 0 Scr 0 0 AZM 2 ALT 2 3.2% 4 6.5% 1 1.6% AZM AZM A-DROP CAP AZM 88.5% VERGIS AZM AZM
5 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS AZM n % 7 FELDMAN CAP AZM American Thoracic Society; ATS AZM 8 CAP AZM AZM AZM 84.5% 9 AZM CAP AZM CAP AZM ARNOLD CAP 10 AZM AZM CAP
6 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June n 7
7 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS n MIC 48.1% 70.6% P % 8.8% P % 91.2% P 0.37
8 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June AZM n AZM n 62 CAP S. pneumoniae Mycoplasma pneumoniae 11,12 30/ % S. pneumoniae 3 AZM
9 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS S. pneumoniae 6 4 AZM AZM S. pneumoniae CAP 13 Prevotella Porphyromonas Fusobacterium MIC AZM 14 AZM % 7 / 4/3 A-DROP AZM 4 S. pneumoniae AZM 30.6% 78.9% 15 grade 2 1 grade 1 VERGIS 11.9% 7.5% 6.0% 7 AZM Scr 42 CAP AZM AZM : 50 57, : , YANAGIHARA, K.; K. IZUMIKAWA, F. HIGA, et al.: Streptococcus pneumoniae 535, MIYASHITA, N.; T. MATSUSHIMA & M. OKA: The 428, : 29 45, 2012
10 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June VERGIS, E. N.; A. INDORF, T. M. FILE, et al.: Intern. Med. 160: , FELDMAN, R. B.; D. C. RHEW ONG, et al.: 163: , ) 10 ARNOLD UMMERGILL, A. S. LAJOIE, et al. in community-acquired pneumonia. Am. J. 1093, ISHIDA, T.; T. HASHIMOTO, M. ARITA, et al.: 1593, SAITO, A.; S. KOHNO, T. MATSUSHIMA, et al.: 63 69, YAMASAKI, K.; T. KAWANAMI, K. YATERA, et al.: community-acquired pneumonia. PLoS ONE 8: e63103, : , JCOG
11 June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS SHINGO NOGUCHI 1, KAZUHIRO YATERA 1, TOSHINORI KAWANAMI 1, KEI YAMASAKI 1, KEIGO UCHIMURA 3, RYOSUKE HATA 3, TAKASHI TACHIWADA 4, KEISHI ODA 1, KANAKO HARA 5, YU SUZUKI 6, KENTAROU AKATA 1, TAKAAKI OGOSHI 2, SUSUMU TOKUYAMA 5, NAOYUKI INOUE 5, CHINATSU NISHIDA 1, TAKESHI ORIHASHI 2, YUGO YOSHIDA 4, YUKIKO KAWANAMI 1, YUSUKE TAURA 6, HIROSHI ISHIMOTO 1, HIDETO OBATA 3, TORU TSUDA 7, CHIHARU YOSHII 2 and HIROSHI MUKAE Azithromycin AZM CAP JRS
THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 June 2014 STFX mg mg mg mg mg 1
June 2014 THE JAPANESE JOURNAL OF ANTIBIOTICS 67 3 175 29 1 2 2 2 2 2 3 4 4 5 5 2 2 1 2 3 4 5 2014 4 15 STFX 50 mg 10% 2011 8 1 100 mg 1 1 2011 12 2013 5 226 1,186 1,089 1,069 2.11% 23/1,089 1.10% 12/1,089
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