会報35号表紙.pdf

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1 35 No. ( )

2 RNA TV chunky 26 RNA 2017 Congratulations

3 RNA

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8 RNA RNA RNA RNA RNA RNA 1-7 -

9 RNA RNA RNA ncrna RNA RNA

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71 ä

72 Akiko Soma (General Affairs Secretary) (ConBio2017) 2017ConBio2017 ConBio2017 RNAConBio2017 RNA

73 Akiko Soma (General Affairs Secretary) RNA RNA

74 9 8 Akiko Soma (General Affairs Secretary) (ConBio2017) 2017ConBio2017 ConBio

75 9 9 Akiko Soma (General Affairs Secretary) ()

76 9 10 Akiko Soma (General Affairs Secretary)

77 9 11 Akiko Soma (General Affairs Secretary) RNA RNAJ

78 RNA 20171

79 RNA RNA RNA RNA RNA RNA

80

81 RNA RNA RNA RNA 1

82 International Symposium on Molecular Biology 2

83 10 50 trna trna TCG T trna Tm trna trna trna 100 Cambridge trna trna trna Ψ trna RNA RNA RNA 3

84 Ψ AUA trna 4

85 REVIEWS Evolution of the genetic code (Oxford) Proc Japan Acad., Ser B. 28 5

86 1. Osawa, S., Ohama, T., Jukes, T.H, Watanabe, K.: Evolution of mitochondrial genetic code I. Origin of AGR serine as stop codons in metazoan mitochondria. J. Mol. Evol., 29: , Osawa, S. Ohama, T., Jukes, T.H., Watanabe, K., Yokoyama, S. : Evolution of genetic code II. Reassignment of codon AUA from isoleucine to methionine. J. Mol. Evol., 29: , Ohama, T., Osawa, S., Watanabe, K., Jukes, T.H. : Evolution of the mitochondrial genetic code IV. AAA as an asparagin codon. J. Mol. Evol., 30: , Yokogawa, T., Suzuki, T., Ueda, T., Mori, M., Ohama,T., Kuchino, Y., Yosihinari, S., Motoki, S., Nishikawa, K., Osawa, S., Watanabe, K. : Serine trna for translation of non-universal codon CUG in Candida cylindracea: Evolutonary implications. Proc. Natl. Acad. Sci. USA, 6

87 , Osawa, S., Jukes,T.H., Watanabe, K., Muto, A.: Recent evidence for evolution of the genetic code. Microbiol. Rev., 56: , Suzuki, T., Ueda, T, Ohama,T., Osawa, S., Watanabe, K. : The gene for serine trna having anticodon sequence CAG in a pathogenic yeast, Candida albicans. Nucleic Acids Res., 21: 356, Ohama, T., Suzuki, T., Mori, M., Osawa, S., Ueda,T., Watanabe, K. : Non-universal decoding of the leucine CUG in several Candida species. Nucleic Acids Res., 21: , Watanabe, K., Ueda, T., Yokogawa, T., Suzuki, T., Nishikawa, K., Mori, M., Ohama, T., Nakabayashi, H., Nakase, T., Osawa, S. : Molecular mechanism of the genetic code variations found in Candida species and its implications in evolution of the genetic code. In K. H. Nirehaus ed., The translational apparatus; pp , Plenum Press, H.Y Watanabe, K., Osawa, S.: trna sequences and variation in the genetic code. In trna: Structure, Biosynthesis, and Function. Soll, D. & RajBhandary, U.L. ed., pp , ASM press,washington, D.C

88 RNA RNA 4 trna RNA 8

89 9

90 G RNA 5 - RNA C4N AUG trna Göttingen F. Cramer Ψ 10

91 trna 2- trna RNA Ψ trna 11

92 12

93 trna trna trna trna RNA trna

94 trna trna 40 14

95 trna A pdf Prof. Erdmann Prof. Sprintzl Prof. Nierhaus. 15

96 RNA 16

97 Ψ 17

98 18

99 19

100 () () 20

101 trna trna NMR NMR 21

102 G1 22

103

104 G1 trna 24

105 62 25

106 26

107 RNA trna

108 trna trna trna RNA trna

109

110

111 12 comfortable Scientific comfortable 31

112 32

113 1990 trna 33

114 34

115 trna 18 trna trna CD 35

116 % trna

117 2005 trna 37

118 RNA () () RNA RNA(tRNA) trna trna trna 2 38

119 trna trna trna 54 2 trna RNA trna DNA trna AGA AGG trna mrna trna trna trna 4 PI 9 5 RNA RNA trna 10 Nucleic Acid Research RNA

120 ( ) 10 ( ) ( ) JB ( ) ( ) ( 9 4 ) ( ) ( ) RNA ( ) (JBIC)( 15 5 ) ( 15 5 ) 40

終 止 コ ド ン か ら ア ミ ノ 酸 指 定 コ ド ンへ の 変 化 は,す べ 対 応 す る こ と を 見 い だ し た14).さ で 説 明 で き る で あ ろ う.ま に か か わ るtRNAGlyUCU遺 伝 子 を 検 出 し,こ Glyコ 翻 訳 に か か わ るtRNAGlyUCC遺 の 変 化 は,こ た,AUAのIleか の 暗 号 を解 読 す るtRNAの

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