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- いおり ふじがわ
- 5 years ago
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6 IUPAC2--N-( ) 2 4.4mg/kg / mg/kg /ADI 5
7 boscalidiso IUPAC 2--N-(4 --2-) 2-chloro-N-(4 -chlorobiphenyl-2-yl)nicotinamide CAS (No ) 2--N-(4'-[1,1'-]-2-)-3-2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-3-pyridinecarboxamide C18H12Cl2N2O BASF BASF
8 14 C Bip- 14 C C Pyr- 14 C- / 1 2 Bip- 14 C- 50mg/kg Bip- 14 C- 500mg/kg Bip- 14 C-Pyr- 14 C- 500mg/kg Pyr- 14 C- Wistar 168 Bip- 14 C %TAR %TAR Bip- 14 C- Pyr- 14 C %TAR %TAR 48 Bip- 14 C %TARBip- 14 C %TAR Bip- 14 C- Pyr- 14 C * Bip- 14 C- 8 Bip- 14 C g/gBip- 14 C g/g Bip- 14 C Bip- 14 C Bip- 14 C- g/g * 8
9 168 Bip- 14 C g/g g /gbip- 14 C- Pyr- 14 C g /g g /g g/g g/g g/g 168 g /g Bip- 14 C- Pyr- 14 C %TAR F01 4 F02F20S- F48S-Bip- 14 C %TAR %TAR %TAR %TAR Bip- 14 C- Pyr- 14 C %TAR %TAR %TAR %TAR Bip- 14 C %TAR Bip- 14 C- Pyr- 14 C %TAR F01F06SH F20S- F48 Bip- 14 C %TAR4.88.5%TAR %TAR 2.84%TAR Bip- 14 C- Pyr- 14 C-F %TARF %TAR F %TAR F20 F02 F05Bip- 14 C- 19.3%TAR 14.2%TAR Bip- 14 C- 4.8%TAR 3.59%TAR 48 % Bip- 14 C- Pyr- 14 C- N.D F F
10 F F F ~ F F N.D. N.D. F48 N.D N.D. N.D. N.D. N.D. F N.D. F N.D %TAR F02F43 F %TAR %TAR %TAR 0.06%TAR F1 F46 F mg/kg / Bip- 14 C- Wistar TAR 6.5.TAR F TARF TAR TAR F TAR 4 Bip- 14 C- Pyr- 14 C- Nadine 1 00g ai/ha mg/kg 5 9
11 Bip- 14 C- Pyr- 14 C- Mueller-Thurgau 1 800g ai/ha 3 45 TRR mg/kg mg/kg mg/kg %TRR %TRR %TRR 6 Bip- 14 C- Pyr- 14 C g ai/ha Hild s Maxi TRR mg/kg mg/kg mg/kg mg/kg mg/kg mg/kg %TRR8.096.%TRR %TRR %TRR %TRR %TRR Pyr- 14 C- F4 9.9%TRR 2.15%TRR 1.2%TRR 1.11%TRRBip- 14 C- F %TRR Bip- 14 C- Pyr- 14 C mg/kg1.022 mg/kg Bip- 14 C %TAR % 15.5%TAR Pyr- 14 C %TAR 25.4% ERR %TAR %TAR F49 F
12 0.2%TAR0.1%TAR 90% F50F49 8 Bip- 14 C- 1mg/kg 30mg/kg Pyr- 14 C- 1mg/kg mg/kg ERR %TAR 3.6.0%TARPyr- 14 C- F4 6.%TARBip- 14 C- 30mg/kg F08 F49F %TAR F50F08 F Pyr- 14 C- 40% 4.6g/g nm 3mW/cm %TAR %TAR K ads = K ads OC= Bip- 14 C - ph 4pH ph 9 3mg/L
13 %TAR %TAR 13 Pyr- 14 C- ph 5 3 g/ml 2.33g/mL nm 3mW/cm %TAR %TAR mg/l nm W/m mg/l mg/l 16 Bip- 14 C - 00g ai/ha 460 g ai./2l %TAR TAR %TAR % TAR CO % TAR 26.5%TAR F % TAR
14 mg/kg mg/kg 160 DF g ai./ha 110 DF mg/kg3.00 mg/kg4.46 mg/kg g (16 ) (65 ) (:53.3 kg) (:15.8 kg) (:55.6 kg) (:54.2 kg) (ppm ff ff ff ff
15 ff / mg/kg mg/kg mg/kg 0,320,800, 800 mg/kg , ,2000, ,128,320, 320 mg/kg 8 800,2000, ,2000,
16 / mg/kg 0,2000,5000 0,2000,5000 0,128,320, 800,2000, 5000 mg/kg mg/kg ,2000, ph 5 0,2000, Wistar ICR Wistar Wistar LD50 5,000 mg/kg LD50 2,000 mg/kg LC50 6. mg/l F49 Wistar LD mg/kg 26 Wistar 10 0, 500, 1000,
17 mg/kg 2000 mg/kg 2000 mg/kg 1000 mg/kg 2000 mg/kg Maximization 30 Wistar 10 0, 100, 500, 2000, 5000, ppm(0,, 34, 13, 34, 10600, 8, 40, 159, 395, 1230 mg/kg /) ppm 5000 ppm -GTP 2000 ppm -GTP 2000 ppm 5000 ppm -GTP 500 ppm34 mg/kg / 2000 ppm 159 mg/kg / 31 C5BL/6 10 0, 150, 1000, 4000, 8000 ppm(0, 29, 19, 88, 15200, 42, 2, 1180, 2210 mg/kg /) ppm 4000 ppm ALT 1000 ppm 1000 ppm 1000 ppm 150 ppm 29 mg/kg /42 mg/kg / 32 16
18 5 0, 250, 2500, ppm( 0,.6, 8.1, 290, 8.1, 81., 825 mg/kg /) ppm ALP 2500 ppm ALP 2500 ppm 250 ppm.6 mg/kg /8.1 mg/kg / 33 Wistar 10 0, 150, 1500, ppm( 0, 10.5, 103, 10500, 12., 125, 120 mg/kg /) ppm1050 mg/kg /120 mg/kg / , 200, 800, 2000, ppm( 0, 5.5, 21.8, 5.4, 5440, 5.8, 22.1, 58.3, 593 mg/kg /) ppm ALP ALT 2000 ppm ALP 2000 ppm 800 ppm21.8 mg/kg /22.1 mg/kg / 35 Wistar 20 0, 100, 500, 2500, ppm 0, 4.4, 21.9, 1100, 5.9, 30.0, 150 mg/kg /15000 ppm
19 2500ppm Ht MCV MCH -GTP 500ppm -GTP 2500ppm 500 ppm -GTP 100 ppm4.4 mg/kg / 5.9 mg/kg / 3655 Wistar 50 0, 100, 500, 2500, ppm 0, 4.6, 23.0, , 29., 156 mg/kg /15000 ppm ppm 2500ppm 500ppm 2500ppm T4 T4 TSH TSH 500 ppm 2500 ppm 100 ppm4.6 mg/kg / 500 ppm29. mg/kg /
20 C5BL/6 50 0, 80, 400, 2000, 8000 ppm(0, 13, 65, 331, , 90, 443, 1800 mg/kg /) ppm 2000 ppm 400 ppm 80 ppm 80 ppm 8000 ppm ppm 400 ppm 2000 ppm 80 ppm13 mg/kg / 400 ppm90 mg/kg / 3855 Wistar 25 0, 100, 1000, ppm 2 (mg/kg /) 100 ppm 1000 ppm 10000ppm P F * ppm P F1F1PF1 F11000 ppm P PF ppm F1F2 F1 F2F2F1F2 19
21 1000 ppm F2F2100 ppm F2 F2100 ppm P F1 F ppm 100 ppm ppm 1000 ppm ppm 100 ppmp 10.1 mg/kg / F mg/kg / 1000 ppmp 10 mg/kg /F1 125 mg/kg / 39 Wistar , 100, 300, 1000 mg/kg / 1000 mg/kg 300 mg/kg 1000 mg/kg / , 100, 300, 1000 mg/kg / 1000 mg/kg /300 mg/kg 1000 mg/kg 300 mg/kg / 100 mg/kg / 1000 mg/kg / 41 20
22 in vitro DNA in vitro S. typhimurium TA100, TA98, TA1535, TA153, E. coli WP2uvrA DNA V9 CHO 20~5500 g/ +/S9 150g/mL 20~500g/mL+/S9 3500g/mLS g/mL+S9 in vivo NMRI 5 500, 1000, /S9 F F49 S. typhimurium 4~5000 g/ TA100, TA98, +/S9 TA1535, TA153 E. coli WP2uvrA +/S9 Wistar , 15000ppm 15000ppm P450 21
23 EROD PROD P Wistar , 15000ppm 15000ppm T3 TSH pnp-gtmuf-gthobi-gt T4 49 Wistar , 500, 2000, 5000ppm 5000ppm 2000ppm ERODPRODBROD T4 TSH 500ppm pnp-gtmuf-gthobi-gt 50 Wistar , 100, 1000, 10000ppm M 51 22
24 14 C Bip- 14 C C Pyr- 14 C % F01F02 F Bip- 14 C Bip- 14 C- Pyr- 14 C- F01F06F20 F48 F02 F05 F4 F K OC ph5 / F mg/kg 3.00 mg/kg4.46 mg/kg LD50 5,000 mg/kg LD50 2,000 mg/kg LC50 6. mg/l F49 LD mg/kg 23
25 / T4 T4 TSH TSH TSH 29 mg/kg / 34 mg/kg /.6 mg/kg / 13 mg/kg / 4.4 mg/kg / 21.8 mg/kg / mg/kg / 1000 mg/kg / 100 mg/kg / 1000 mg/kg / in vitro DNA F
26 mg/kg / P 10.1 P 10. F F mg/kg / GTP GTP P 101 P 10 F1 124 F mg/kg / mg/kg /ADI ADI 0.044mg/kg / ADI mg/kg /
27 1/ F01 2--N-( ) F [[(2--3-)]]-3- F05 [3-[[(4 --2-)]]-2-] F06 N-(4 --2-)-2- F08 N-(4 --2-) F20 2--N-(4 --?--?--2- ) F43 N-(4 --2-)-2- N 5 -(2-[()]-1-[[(5-(4-)-4-[[(2- F46-3-)]]-6--2,4--1- )]]-2-) F4 2- F48 3-[[( )-]] F49 N-(4 --2-)-2- F50 2--N-(4 --2-)-?- F F ?- 26
28 2 ai ALP ALT BROD - O - EROD - O - ERR -GTP - HOBI-GT 4-- Ht MCH MCV MUF-GT 4-- PHI pnp-gt p -- PROD - O - T3 T4 TAR TRR TSH 2
29 g ai./ha () PHI (mg/kg) DF DF DF DF * 0.12* DF DF DF DF DF DF DF DF * 0.03* 0.01* 28
30 DF DF DF DF SE SE SE * 0.02* 0.02* SE WDG SE DF DF DFSESE < * 29
31 BASF 2004 URL: C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF C-GLP BASF GLP C-GLP BASF C-GLP BASF C-GLP BASF GLP C-/GLP SLFA BASF BASF BASF BASF GLP BASF GLP GLP BASF
32 25. GLP BASF F49BASF Wistar GLP BASF GLP BASF GLP BASF GLP BASF GLP BASF GLP BASF GLP BASF Wistar 90 GLP BASF GLP BASF Wistar 24 GLP BASF Wistar 24 GLP BASF GLP BASF GLP BASF GLP BASF GLP BASF GLP BASF V9 in vitro GLP BASF GLP BASF in vitro DNA UDSGLP BASF CHO in vitro HPRT GLP BASF F49 BASF
33 48. 2 GLP BASF GLP BASF GLP BASF GLP URLhttp:// jp/iinkai/i-dai21/dai21kai-siryou1.pdf (URLhttp:// /iinkai/i-dai21/dai21kai-siryou2-1.pdf) URLhttp:// n-dai4/index.html BASF URLhttp:// n-dai9/index.html URLhttp:// BASF 200 URL: BASF BASF URLhttp://www. fsc.go.jp/iinkai/i-dai109/dai109kai-siryou1-1.pdf (URLhttp:// URLhttp:// n-dai39/index.html b URL
34 URL URL
参考資料５ 農薬評価書 メタアルデヒド（食品安全委員会資料）
1 3 3 4 5. 6 1. 6 2. 6 3. 6 4. 6 5. 6 6. 6 7. 6. 7 1. 7 2. 8 (1) 8 (2) 9 (3) 9 (4) 10 (5) 10 3. 11 (1) 11 (2) 11 (3) 11 (4) 12 4. 12 (1) 12 (2) 12 (3) 13 5. 13 6. 13 7. 14 8. 15 9. 16 10. 16 (1) 90 16-1
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2001 4 26 2003 5 22 2004 7 12 2004 7 15 54 2004 7 21 14 2004 9 16 62 IUPAC4--2--N,N --5-p --1-2 17.07 mg/kg / 100 0.17 mg/kg /ADI cyazofamidiso IUPAC 4--2--N,N- -5-p --1-4-chloro-2-cyano-N,N -dimethyl-5-p
1 1 641 1 4 44 436 4610 1 1 10 4 3 4 9418 764 4 9 18 6 8 864. 8.844 4 44 6 1 3 6 1 3 4 6 7 8 8 10 3 3 6 7 7 1 717. 17. 88 8 384 4 37 630 30 714 4 6 1 3 4 6 3 4 1 4 3 1 6 6 9 1 1 18 3 3 6 3 8 4 4 436 410
CSR報告書2005 (和文)
A 250 200 150 100 50 0 25,000 20,000 15,000 10,000 5,000 0 1,000 800 600 400 200 0 168 14 14 27 54 60 2000 16,975 1,314 1,207 8,977 5,477 2000 698 112 115 292 178 2000 223 24 28
ブック 1.indb
21 1211 27 11 27 12 16 20 11 27 10 20 28 29 30 12 10 11 12 30 13 30 14 10 30 15 11 16 12 17 13 18 14 19 15 20 16 10 21 11 27 106 21 107 108 109 110 21 111 28 112 28 10 113 29 11 11421 30 12 11521 32 13
,309 t 22,069 t 7,240 t µg/l µg/l < ,431-70, , , mg/l m
1 20019 1527 CAS 1317368 1230 PbO 223.20 1 99 1. 2 888 2 9.53 0.017 g/l 20 3 3 2 2. 10 29,309 t 22,069 t 7,240 t 4 1 3. 1 2 3.5 6 1 µg/l 9.1-24 2 µg/l < 43 6 27,431-70,000 4.5-1,300 13.4-17 31.7 0.48-3,459
38
979 25 98 594 324 333 348 347 35 23 78 44 758 37 38 24 8 2 7 44 32 8 2 2 24 7 4 3 2 9 8 7 3 6 4 3 7 4 8 2 5 2 6 3 24 8 3 74 46 344 9 6 2 3 2 24 7 4 3 2 2 9 9 7 3 2 4 3 758 223 39 () 96.5g (2),33.6g 24.572g,33.6g
<4D F736F F D2095BD90AC E E838B8C6E8EBE8AB382CC93AE8CFC82C98AD682B782E9838A837C815B83675F2E646F6378>
29 4 IT 1,234 1,447 1 2 3 F20-F29 F20,F21,F22 F23,F24,F25, F28F29 F30-F39 F30,F31,F32 F33,F34,F38 F39 F40-F48 F40,F41,F42 F43,F44,F45 F48 1,234 14,472,130 75,784,748 9,748,194 47,735,762 4,723,984 28,048,986
- 108 -
3-107- - 108 - 3.1 3.1.1 3.1.2 3.1.2.1 5 LD50 LC50 ATE 3.1.1 1 2 3 4 5 (mg kg ) 5 50 300 2000 5000 a (mg kg ) 50 200 1000 2000 a (ppm) 100 500 2500 5000 a b mg 0.5 2.0 10 20 a b c d 0.05 0.5 1.0 5 (mg
まえがき
JAAS0012006 1 -------------------------------------------------------------------------------------------------------- 1 2 --------------------------------------------------------------------------------------------------------
(1) (2) (1) (2) (1) Seg (2) Seg (3) Seg (4) Seg (1) (2) (3) ( ) (1) (PCA)...12
(1)...109 (2)...110 (1) 28...111 (2) 28...113 (1) Seg...115 (2) Seg...117 (3) Seg...119 (4) Seg...120 (1)...122 (2)...122 (3) ( )...126 (1) (PCA)...127 (2) Draize...128 (1) Ames...129 2 in vitro...132
,977 t 157,977 t mg l mg l BOD 9398 % OH = cm 3 / sec 11 = cm 3 / sec OH = /
1 9625 2219 CAS 75569 1, 2-1, 2- H 2 C CH CH 3 C 3 H 6 O 58.08 1 99 % 1. 2 2, 3-112.13 2, 3 34.23-37 449 2.8-37 % 2 d 0 4 0.859 4 d 20 0.8304 2 2, 4 2.00 = 1 53.33 kpa 400 mmhg18 59.33 kpa 445 mmhg20 5
3, ,104 t mg/l 30 mg/l BOD mg 14 C 8, /kg 11 8, 1 11 OH = cm 3 / sec 11 OH /cm ppm
3, 3-1 200019 4800 CAS 91941 1138 3, 3-4, 4 - -3, 3 - H 2 N Cl Cl NH 2 C 12 H 10 C l2 N 2 253.13 1 95 1. 2 3, 4 132-133 402 5 >200 5 700kg/m 3 5 8.73 = 1 5.610-8 kpa 4.210-7 mmhg20 4 6 log Pow3.51 3.57
20 57
56 20 57 58 59 12 60 ph 61 62 CCA 63 64 ( 1) 700 7.5 86% 54 17 71 2) 700 6.8 86% 50 15 65 3) 600 700 5.7 84% 36 14 50 550 650 4.2 80% 21 6 27 40 500 3.6 78% 16 7 23 3.6 78% 16 7 23 400 700 4.0 78% 18 7
199004_渓仁会_年次報告書
() () () () () () () () () () () () () () () (4) (5) (6) 4 (7) 5 (8) 6 (9) 7 () 8 () 7 4 5 () 6 () 6 7 9 () 4 () 4 () 4 () 4 () 4 () 4 () 4 () 4 () 44 45 () 4 46 () 48 () 48 () 49 () 49 5 () 5 () 5 ()
5 IT 1,280 1, , ICD -10 <1> <2> <3> F20-F29 F20,F21,F22 F23,F24,F25, F28F29 F30-F39 F30,F31,F32 F33,F34,F38 F39 F40-F48 F40,F41,F42 F43,F
5 IT 1,280 1,568 1 3,862 2 3 ICD -10 F20-F29 F20,F21,F22 F23,F24,F25, F28F29 F30-F39 F30,F31,F32 F33,F34,F38 F39 F40-F48 F40,F41,F42 F43,F44,F45 F48 15,680,980 138,623,755 1,280 10,284,893
CAS H 3 C C CH 2 C 9 H tert d = hpa
1 200140 35 CAS 98839 1335-2- H 3 C C CH 2 C 9 H 10 118.18 1 99 4-tert- 1. 2-23.2 2 163164 2 54 574 3 0.96.6 20 d 4 0.9082 2 4.07 = 1 2.5 hpa 1.9 mmhg20 2 4 log Pow3.48 3.44 m/z 118, 1.0 103 0.58 91 0.21
14 4 12 10 8 6 3 2 4 2 1 0 0 100200300400500600 100200300400500600700 0 0 100200300400500600 100200300400500600700 (ppm) (ppm) 7 4 6 5 4 3 3 2 2 1 1 0 0 100200300400500600 100200300400500600700 0 0 100200300400500600
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b 0 1PPm 10PPm 100PPm 1000PPm 10000PPm 0.0001% 0.001% 0.01% 0.1% 1% 10% 1PPm 10PPm 100PPm 1000PPm 10000PPm 0.0001% 0.001% 0.01% 0.1% 1% 10% 1PPm 10PPm 100PPm 1000PPm 10000PPm 0.0001% 0.001% 0.01%
040202PC用.doc
15 48 15 8 25 15 1321 15 8 25 0825002 15 8 25 6 8 15 2 18 15 6 27 2 15 3 13 28 35 (1) 51 198 7 (2) 3 6 1 100g (1) 1 (1) 1 2 1 astaxanthin;3,3 -dihydroxy-, -carotene-4,4 -dione (2) 1 2 C40H52O4 596.86 97.0
,161 t 9,753 t 2,408 t LC 50 mg/ L EC 50 mg/l * 5 : Selenastrum 6772-h, Sb 2 O 3, : capricornutum 6 3 Selenastrum h, Sb
1 20017 1543 CAS 1309644 125 Sb 2 O 3 291.52 1 99 1. 2 655 1,425 2 2 2 3 5.2 5.67 2 2 2. 10 12,161 t 9,753 t 2,408 t 4 3. 1 2 3 4. LC 50 mg/ L EC 50 mg/l * 5 : Selenastrum 6772-h, Sb 2 O 3, : capricornutum
服用者向け_資料28_0623
1 2 3 1. 2. 4 3. 4. 1. 5 2. 3. 4. 5. 6 6. 7. 8. 7 9. 10. 11. 8 12. 9 10 11 12 Q-1 : OC Q-2 : OC Q-3 : 21 OC 28 OC 13 Q-4 : OC Q-5 : OC Q-6 : OC 14 Q-7 : Q-8 : OC Q-9 : OC Q-10 : OC Q-11 : OC 15 Q-12 :
橡99-24_00 アリルアルコール.PDF
1 9924 2260 CAS 107186 H 2 C CH CH 2 OH 2- -1- C 3 H 6 O 58.08 1 99 1. 2, 3 3, 4, 5-129 96-97 2 21c.c. 24o.c. 2 6, 7 378 6, 7 2.5-18 d 20 4 0.8540 2, 5 2.00 = 1 2.7 kpa 20 mmhg204.3 kpa 32 mmhg30 4 log
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ver. 3.3JT EVENING PRIMROSE EXTRACT 1 - PMS 1 2 1 4 Oenothera laciniata Oenothera striata Oenothera biennis Oenothera erythrosepala - 2 80 60 40 20 0 1. 2 3 PGGPAC 2. 3 4 ESR3.5 10 5 /g 4 3 1 Helicobacter
橡96-07.PDF
1 967 2482 CAS 50000 CH 2 O 30.03 2952% 12.5 % 1. 2) -92 2) -19.5 2) 5085 3) 424 3) 7.073.0% 4) 20 d 4 0.815 5) 1.03 ( = 1) 5) 1.33 kpa (10 mmhg) (-88.0) 2) log Pow0.35 ( ) 6) 0.35 ( ) 7) 1) m/z 29 ( 1.0
CAS O C O * DOP* DEHP 2- C O O * n- C 24 H 38 O CH 2 CH 2 CH 2 CH 3 CH (CH 2 ) % 2- A BHT , 4
2-1 9628 31307 CAS 117817 2- O C O * DOP* DEHP 2- C O O * n- C 24 H 38 O 4 390.56 CH 2 CH 2 CH 2 CH 3 CH (CH 2 ) 3 1 99 % 2- ABHT 1. 2-55 3 3, 4 386 171 350 6 0.1 % d 20 4 0.9861 4 13.48 0.30410-4 Pa 2.2810-7
橡96-01.PDF
1 961 31 CAS 71432 C 6 H 6 78.11 1) 99 % 1. 5.5 2) 80.1 2) -11 3) 293563 3) 1.48.0% 3) d 20 0.8786 4) 2.77 ( = 1) 4) 4 13.33 kpa (100 mmhg) (26.9) 2) log Pow2.13 ( ) 5) 2.14 ( ) 6) m/z78 ( 1.0 )77 ( 0.20
ver5.1 HS 1. ALPHA LIPOIC ACID () S S COOH HS 1. α - SH COOH - ( 1) CoA -( 2)- - --P80 (--WSP8-L1-WSPC8 -LC1) - 1
ORYZA OIL & FAT CHEMICAL CO., LTD. ALPHA LIPOIC ACID --P () --P80 () --WSP8 () --L1 () --PC () --PC80 () --WSPC8 () --LC1 () ver. 5.1HS ver5.1 HS 1. ALPHA LIPOIC ACID 16 3 31 0331009 - () 19 5 24 0524001
現しないものと考えられた 代謝物 F001 F033 F049 では細菌を用いた復帰突然変異試験が実施されており 全て陰性であった 各試験における無毒性量及び最小毒性量は表 26 に示されている 表 26 各試験における無毒性量及び最小毒性量 動物種 試験 無毒性量最小毒性量 (mg/kg 体重 /
オリサストロビンの急性経口 LD 50 はラットの雄で 356 mg/kg 体重 / 日超 雌で 356 mg/kg 体重 急性経皮 LD 50 はラットの雌雄で 2,000 mg/kg 体重超 急性吸入 LC 50 はラットの雄で 4.12 mg/l 雌で 1.04 mg/l であった 亜急性毒性試験で得られた無毒性量は ラットで 6.8 mg/kg 体重 / 日 イヌで 27.5 mg/kg 体重
2 1 2 3 27 2 6 2 5 19 50 1 2
1 2 1 2 3 27 2 6 2 5 19 50 1 2 2 17 1 5 6 5 6 3 5 5 20 5 5 5 4 1 5 18 18 6 6 7 8 TA 1 2 9 36 36 19 36 1 2 3 4 9 5 10 10 11 2 27 12 17 13 6 30 16 15 14 15 16 17 18 19 28 34 20 50 50 5 6 3 21 40 1 22 23
% %
4 8 4 5 414.5 172.1 41.5% 39.8 10% 17 186.4 70.8 4 9 10 11 3 1-1 - 2-2 - - 3 - 10% - 4 - 4060% 5560% 60% 40% 3040 1520 1015 411 7 4 11 610 7080 5060 100 3040 13-5 - 1015 4045 3.04.0 5.06.0 1.52.0 1.01.5
年次報告書－2003年（平成15年）度版－
9876 ,g,g,g,9g 8 6 6 6 6 8 7 8 6 7 8 7 9 7 6 6 6 7 7 8 6 8 7 6 6 8 7 8 7 7 9 7 6 98 76,8 () ( ) 8,68.7 7,76, 9,87.9 8,67, () g g g g g g g g g g g g g g g g g g g g g g g g g g g g () () 9 8 88 6 8 88
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t 492 t mg/l 30 mg/l BOD 95 OH = cm 3 / sec 25 8 OH /cm 3 12 = ph ph
2-1 200169 2740 CAS 110-49-6 1103 2- O H 3 C C O CH 2 CH 2 O CH 3 C 5 H 10 O 3 118.13 200168 2-1 99 2-1. 2 2, 3-65 2, 3 144145 45 o.c. 3 392 3 1.512.3 d19 1.009 2 4.07 = 1 30 Pa 0.23 mmhg20 2 4 log Pow0.10
（配布資料２）【食品安全委員会】滋賀県食の安全安心シンポジウム
1 2 3 2003(Codex, FAO/WHO) 4 ( ) 5 6 ( ) 1 2 7 ADI MRL 8 9 10 11 1cm 12 600-2,700μg RAE/ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 100 100 1 ADI 1 27 ADI NOAEL 28 mg/kg / mg/kg / 29 30 /kg / 24 23 31 32
(1) ) ) (2) (3) (4) (5) (1) (2) b (3)..
... -1... -1... -2... -6.... -1 (1)... -1 1)... -1 2)... -14 (2)... -19 (3)... -52 (4)... -18 (5)... -136.... -196 (1)... -196 (2) b... -224 (3)... -233.... -251.... -286.... -289 (1)... -289 (2)... -32
エクラー軟膏0.3%、エクラークリーム0.3%、エクラーローション0.3%_IF
2005 1 872646 IF 1998 9 1g 3mg(0.3%) Deprodone Propionate 2003227 200374 1997415( ) 1998316( ) F A X 2003 7 1992 3 17 1997 10 9 1992 5 22 1997 12 19 IF 2005 4 IF 1. MR 63 2 IF 10 3 IF 2. IF IF IF 3. IF
パソコン接続マニュアル P-01F 日本語
P-01F 1 2 3 4 5 1 2 +m1111 1 2 3 4 5 6 6 1 1 111 2 1 3 1 1 1 2 1 7 3 8 1 2 1 111 3 4 5 9 1 m111 m1111 c 2 3 4 5 10 1 1 111 2 1 3 1 1 1 2 1 3 1 m111 m1111 2 3 1 11 12 1 2 3 1 2 3 13 1 2 3 4 5 14 6 7 8 9
125 2 P 1st washout 2 PB P mg/dL nd washout 2 P 5.5mg/dL< mg/dL <2.5mg/dL P P 2 D D 3 Ca 10
. (1) 125 1 125 Renagel PB-94 P intact-pth P 1 b c a b 1 18 2 3 3 3 1 P 4 D 1 5 6 7 2 1HIV 2 3 4 5Hb 8.0g/dL ALT 48IU/L 6 7 PB-94 440mg 403mg 1-196 125 2 P 1st washout 2 PB-94 1 2 4 4 P 2.5 5.5mg/dL 1
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橡三酸化二アンチモン.PDF
1 2001 7 1 543( ) CAS 1309 64 4 1 25 ( ) Sb 2 O 3 291.52 1) 99 1. 2) 655 3) 1,425 3) ( ) 2) ( ) 2) ( ) 2) 5.2 ( ) 5.67 ( ) 3) 2) 2. 10 12,161 t ( 9,753 t 2,408 t) 4 2 1) 3. 1) 2) 3) 4. Selenastrum capricornutum
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ORYZA CERAMIDE -PTPCDP8TP20CD -WSPWSP8 -LL0.8 -PCPC8PC20 -WSPCWSPC8 -LCLC0.8 Ver.13.0HS ORYZA CERAMIDE Ver.13.0HS 1. 2. 20 NMR 4 ( 1) 1 Ver.13.0HS HO CH 2 OH O O OH OH OH C CH CH H 2 NH C O R C H C H (CH
製品案内 価格表 2014/4/1
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３．ごみの減量方法.PDF
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0120-888-089 0120-919-498 160-83381-26-1TEL. 03-3349-3111 URL http://www.sjnk.co.jp/ 160-83381-26-1 TEL. 03-3349-3111 URL http://www.sompo-japan.co.jp/ 100-89653-7-3 TEL. 0120-919-498 URL http://www.nipponkoa.co.jp/
表紙.PDF
2 3 4 2001 2010 33 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 H18 21 22 23 24 25 26 27 28 29 30 31 32 33 300 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 410-8601 055-934-4747 Fax 055-933-1412
農林金融2015年5月号
4 5 4 4 4 4 2014 5 14 7 2050 1412 15 3 19 1800 1 1 2 2 2 126 2 3 1 2 1 2 3 4 1 1 2 2 1 1 2014 3 2 126 2 2 3 1 40 30 20 10 0 2014 26 287 339 393 399 361 2 2 11 1 3 25 4 4 5 5 19898993 96 3 2000 1 1 1 5
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2011 11 4 871319 1mL 5mg 5mg15 1g 5mg 5mg15 JAN JAN Erythromycin LactobionateJAN Colistin Sodium MethanesulfonateJAN 1970 3 31 1970 8 1 1970 7 20 TEL0120-921-839 06-6321-7056 9 17 https://www.santen.co.jp/medical/admin/a300.jsp
橡フタル酸ブチルベンジル.PDF
1 97 7 3 1312 CAS 85 68 7 O BBP 1, 2- C 19 H 20 O 4 312.4 C C O O O (CH 2 ) 3 1 99.9 % 1. 2-35 3 2, 3 370 3, 4 199 d 25 4 1.117 2 10.8 = 1 5 1.15 10-3 Pa 8.6 10-6 mmhg 20 5 253 Pa 1.9 mmhg 200 5 log Pow
N i p p o n h a m AI R M A I L A C h i n a I R M A I L V i e t n a m AI R M A I L 61 62
Enterococcus faecium 59 60 N i p p o n h a m AI R M A I L A C h i n a I R M A I L V i e t n a m AI R M A I L 61 62 N i p p o n h a m A I R M A I L C a n a d AI R M AIL a Topics M e A x i I R M A c o I
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98-02.PDF
1 982 2207 CAS 67630 2- H 3 C H 3 C CH OH C 3 H 8 O 60.10 1 99.9 % n- 1. 2-88.5 3 82.5 3 11.7c.c. 455 4 212 d 20 4 0.78505 3 2.1 = 1 4 4.4 kpa 33 mmhg20 4 log Pow0.05 0.07 5 m/z45, 1.0 43 0.19 27 0.17
CTD 2 2.6 5.3mg 0.4mg 0.6mg 0.8mg 1.0mg 1.2mg 1.4mg 1.6mg 1.8mg 2.0mg 12mg 2.6 Page 3 2.6.6...5 2.6.6.1...6 2.6.6.2...9 2.6.6.3...9 2.6.6.4... 11 2.6.6.5... 11 2.6.6.6... 11 2.6.6.7... 11 2.6.6.8... 11