|
|
|
- ありかつ はらしない
- 5 years ago
- Views:
Transcription
1 Kazumitsu Ueda, uedak@kais.kyoto-u.ac.jp http : //cseika-1, kais.kyoto-u.ac.j p Molecular mechanism of multidrug transporter MDR I : ABC in host-defense machinery
2
3
4 32P-ATP
5
6
7 1) Chen, C., Chin, J.E., Ueda, K., Clark, D.P., Pastan, I., Gottes man, M.M., Roninson, LB.: Cell, 47, (1986) 2) Ueda, K., Clark, D.P., Chen, C.-J., Roninson, LB., Gottesman, M.M., Pastan, I.: J. Biol. Chem., 262, (1987) 3) Ueda, K., Cardarelli, C., Gottesman, M.M., Pastan, I.: Proc. Natl. Acad. Sci. USA, 84, (1987) 4) Schinkel, A.H., Smit, J.J., van Tellingen, 0., Beijnen, J.H., Wagenaar, E., van Deemter, L., Mol, C.A., van der Valk, M. A., Robanus-Maandag, Borst, P. : Cell, 77, (1994) E.C., to Riele, H.P., Berns, A.J.M., 5) Lankas, G.R., Cartwright, M.E., Umbenhauer, D.: Toxicol. Appl. Pharmacol., 143, (1997) 6) Ueda, K., Matsuo, M., Tanabe, K., Kioka, N., Amachi, T. Biochim. Biophys. Acta, 1461, (1999) 10) Saeki, T., Ueda, K., Tanigawara, Y., Hori, R., Komano, T. FEBS Lett., 324, (1993) 11) Saeki, T., Ueda, K., Tanigawara, Y., Hori, R., Komano, T. J. Biol. Chem., 268, (1993) 8) Ueda, K., Okamura, N., Hirai, M., Tanigawara, Y., Saeki, T., Kioka, N., Komano, T., Hori, R. : J. Biol. Chem., 267., (1992) 9) Tanigawara, Y., Okamura, N., Hirai, M., Yasuhara, M., Ueda, K., Kioka, N., Komano, T., Hori, R. : J. Pharmacol. Exp. Ther., 263, (1992) 13) Ueda, K., Taguchi, Y., Morishima, M. : in Seminars in Can cer Biology (ed. Borst, P.), pp , Academic Press, London (1997) 14) Zheleznova, E., Markham, P., Neyfakh, A., Brennan, R. Cell, 96, (1999) 15) Vazquez-Laslop, N., Markham, P., Neyfakh, A.: Biochem
8 istry, 51, (1999) 16) Akabas, M.H., Kaufmann, C., Cook, T.A., Archdeacon, P. J. Biol. Chem., 269, (1994) 17) Taguchi, Y., Kino, K., Morishima, M., Komano, T., Kane, S. E., Ueda, K.: Biochemistry, 36, (1997) 18) Taguchi, Y., Morishima, M., Komano, T., Ueda, K. : FEBS Lett., (1997) 19) Senior, A.E., al-shawi, M.K., Urbatsch, I.L.: FEBS Lett., 377, ) 20) Urbatsch, I.L., Sankaran, B., Bhagat, S., Senior, A.E. : J. Biol. Chem., (1995) 21) Nagata, K., Nishitani, M., Matsuo, M., Kioka, N., Amachi, T., Ueda, K. : J. Biol. Chem., 275, (2000) 22) Taguchi, Y., Yoshida, A., Takada, Y., Komano, T., Ueda, K.: FEBS Lett., 401,11-14(1997) 23) Sun, H., Smallwood, P., Nathans, J.: Nature Genet., 26, (2000) 24) Allikmets, R., Shroyer, N., Singh, N., Seddon. J., Lewis, R., Bernstein, P., Peiffer, A., Zabriskie, N., Li, Y., Hutchinson, A., Dean, M., Lupski, J., Leppert, M. : Science, 277, (1997) 25) Sun, H., Molday, R., Nathans, J.: J. Biol. Chem., 274, (1999) 26) Hopfner, K., Karcher, A., Shin, D.S., Craig, L., Arthur, L.M., Carney, J.P., Tainer, J.A. : Cell, 101, (2000) 27) Hung, L.-W., Wang, IX, Nikaido, K., Liu, P.Q., Ames, G.F., Kim, S.H. : Nature, 396, (1998) 28) Loo, T.W., Clarke, D.M. : J. Biol. Chem.. 275, (2000) 29) Jones, P.M., George, A.M.: FEMS Microbiol. Lett., 179, (1999) 30) Diederichs, K., Diez, J., Greller, G., Muller, C., Breed, J., Schnell, C., Vonrhein, C., Boos, W., Welte, W. : EMBO J., 19, (2000) 31) Berge, K.E., Tian, H., Graf, G.A., Yu, L., Grishin, N.V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R., Hobbs, H. H.: Science, 290, (2000) 32) Schmitz, G., Kaminski, W.E., Orso, E.: Curr. Opin. Lipidol., (2000) training info-lsf@senri lc.co.jp http : //
Kazumitsu Ueda, [Department of Applied Life Science, Kyoto University Graduate School of Agriculture, Kitashirakawa, Sakyo-ku, Kyoto 606-01, Japan] Molecular Mechanisms for Drug Transport by MDR1/P-glycoprotein
Kazuo Emoto, Masato Umeda, E-mail : emoto@rinshoken.or.jp pliakov, 0., De Camilli, P.: Neuron, 24, 143-154 (1999) 8) Takei, K., Haucke, V., Slepnev, V., Farsad, K., Salazar, M., Chen, H., De Camilli,
1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,
Correlation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)
The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey
The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Key words Shigeyuki Kawai, Chikako Fukuda, Kousaku Murata E-mail : kawais@kais.kyoto-u.ac.jp, chikakko@kais.kyotou.ac.jp,
drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:
Database Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*,
(http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, E mail : takaabe@mail.cc.tohoku.ac.jp Taro Tokui, Molecular identification of organic anion transporter
Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,
tary adenylate cyclase activating polypeptide ; PA-
Conformation of a peptide ligand bound to its G-protein coupled receptor and its implication for ligand transportation tary adenylate cyclase activating polypeptide ; PA- molecular biology (ed. Rich,
10中西_他.indd
Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab
2
1999 No. 5 CHAPERONE NEWSLETTER CONTENTS 2 3 4 JEM JEM JEM, SEC, SCJ JEM JEM SCJ jem, scj 5 in vitro S. cerevisiae 6 K 7 in vitro Cell Mol. Cell in vitro 8 9 E. coli E. coli 10 in vitro ssc - b 11 in vivo
Spatio-temporal regulation of ERK1/2 MAP kinase 20) Murphy, L. 0., MacKeigan, J. P., Blenis, J.: Mol. Cell. Biol., 24, 144-153 (2004) 21) Harada, T., Morooka, T., Ogawa, S., Nishida, E.: Nature Cell
Database Center for Life Science Online Service
Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service SMN (Survival
Florigen in rice Key words Shojiro Tamaki, Ko Shimamoto E-mail : s-tamaki@bs.naist.jp, simamoto@bs.naist.jp URL : http://bsw3.naist.jp/simamoto/simaoto.html 1) Thomas, B., Vince-prue, D.: Photoperiodism
Minamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555
表1.eps
Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol
[Nippon Nogeikagaku Kaishi
[ Nippon Nageikagaku Kaishi Vol. 72, No. 11, pp. 1333 `1344, 1998 l Key words: methylotrophic yeast; gene expres sion; C1-metabolism; peroxisome Cellular Functions of the Methylotrophic Yeast: Their Molecular
4) H. Takayama et al.: J. Med. Chem., 45, 1949 (2002). 5) H. Takayama et al.: J. Am. Chem. Soc., 112, 8635 (2000). 6) H. Takayama et al.: Tetrahedron Lett., 42, 2995 (2001). 9) M. Kitajima et al: Chem.
Novel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,
Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal
Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal transduction Needleman, R., Lanyi, J. K. : Science, 269,73-75 (1995) 3) Bogomolni, R. A., Stoeckenius,
Review Fumio Imamoto1, Takefumi Sone1, Kazuhide Yahata1, Yukari Sasaki1, Masatoshi Takagi2, Kazuhiro Maeshima2, Naoko 25) Dong, W. K. et al.: Gene, 91, 217-223 (1990) 26) Masatsugu, T. et al.:
Database Center for Life Science Online Service Structure and function of nitric oxide synthases
Structure and function of nitric oxide synthases 3) Furchgott, R. F., Zawadzki, J. V. : Nature, 288,373-376 (1980) 4) Palmer, R. M., Ferrige, A. G., Moncada, S.: Nature, 327,524-5260987) 5) Alderton,
Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie
Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie Universitat Freiburg Zentrum fur Molekulare Biologie (ZMBH) Universitat Heidelberg E-mail : bukau@zmbh.uni-heidelberg.de
Database Center for Life Science Online Service
1) Epps, H. M., Gale, E. F.: Biochem. J., 36, 619-623 (1942) 2) Monod, J.: Recherches sur la croissance des cultures bacteriennes, Ph. D. thesis. Her mann,paris (1942) 3) Magasanik, B.: Cold Spring Harbor
Short Review E-mail : kuwata@cc.gifu-u.ac.jp Structural medicine and structure-based drug design for prion diseases 2) Anfinsen, C. B.: Harvey Lect., 61, 95-116 (1967) 3) Carrel, R. W., Lomas, D. A.
1) Y. Hatefi: Annu. Rev. Biochem., 54, 1015 (1985). 2) H. Weiss, T. Friedrich, G. Hofhaus & D. Preis: Eur. 4) M. Yamaguchi & Y. Hatefi: Biochemistry, 32, 1935 (1993). 5) K. Leonard, H. Haiker & H. Weiss:
Tomohiro Terada, Ken-ichi Inui, Peptide transporter family situ 1) Matthews, D.M. : Physiol. Rev., 55, 537-608(1975) 2) Ganapathy, V.. Leibach, F.H.: Am. J. Physiol. Gastro intest. Liver Physiol.,
Bio-No.57/3....
2004. MAR. 3No.57 http://www.wako-chem.co.jp C O N T E N T S 2 Wako Bio Window No.57 MAR.2004 l l l l wako wako l l mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmm Wako Bio Window No.57 MAR.2004 3 4 Wako Bio Window
Teru Ogura, Tomoko Yamada-Inagawa, E-mail : ogura@gpo.kumamotou.ac.jp AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins 29) Braun, S.,
Database Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate
Signal transduction of growth factor mediated by heparin heparan sulfate 1) Zhu. X.. Komiya, H., Chirino, A.. Faham. S.. Fox, G. M., Arakawa, T., Hsu, B.T., Rees, D. C.: Science. 251, 90-93 (1991)
Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap
Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan] Molecular Basis of Triplet Repeat Diseases : Genetic Instabillity and Unusual DNA
Database Center for Life Science Online Service Chiharu Ueguchi, Molecular mechanism and biological function of t
Chiharu Ueguchi, E-mail : cueguchi@agr.nagoya-u.ac.jp Molecular mechanism and biological function of the cytokinin signal tansduction pathway 1) Miller, C. 0., Skoog, F., von Saltza, M. H., Strong,
E-mail : tmatsumo@house.rbc.kyoto-u.ac.jp htm Spindle checkpoint : Cell cycle regulation by a signal emitted from kinetochores http://www.rbc.kyoto-u.ac.jp/radiation_system/m-index. 19) Yao, X., Abrieu,
本文／ＹＡ４２７８Ｉ
pp. D- D-DAO DAO D- D- D- D- o- DAO-D- D-DAO DAO Hans Krebs FAD X DAO DAO DAO D- Structure and reaction mechanism of D-amino acid oxidase Yasuzo Nishina School of Health Sciences, Kumamoto University,
Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara,
Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara, E-mail : horikosh@iam.u-tokyo.ac.jp http://www.iam.u-tokyo.ac.jp/homasami/ 1) Jacob, F., Monod, J. : J. Mol. Biol., 3, 318-356 (1961) 2) Ptashne,
Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Review Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge E-mail : m.mishima @gurdon.cam.ac.uk http://www.gurdon.cam.ac.uk/groups/mishima.html Cytokinesis :
Lipids of Seeds Manjiro NODA Department of Agricultural Chemistry, College of Agriculture, Kyoto Prefectural University (Sakyo-ku, Kyoto)
Lipids of Seeds Manjiro NODA Department of Agricultural Chemistry, College of Agriculture, Kyoto Prefectural University (Sakyo-ku, Kyoto) and Other Lipids", Vol. 11, p. 137 (1970) 2) C.Y. Hopkins,
untitled
Fig.1 t O O N,N p n J J J J J t J J J J J J J J J J J t t J J J J J J J J J p Fig.2 p t Fig.3 Fig.4 synanti p Table1 Table2t Table2 synanti antisyn synanti synanti Fig.5 syn anti anti Fig.6 Table3 Table4
Stress-responsive MAP kinases 15) Lu, H. T., Yang, D. D., Wysk, M., Gatti, E., Mellman, I., Davis, R. J., Flavell, R. A. : EMBO J., 18,1845-1857 (1999) 16) Lu, B., Yu, H., Chow, C., Li, B., Zheng,
3) Z. Nambu: in preparation (1971). 4) N. P. Wilkins & J. D. Iles: Comp. Biochem. Physiol., 17, 1141 (1966). 5) V. M. Ingram: Nature, 235, 338 (1972). Bacillus cereus var. mycoides, Bacillus thuringiensis
宿 主 特 異 性 を決 定 す る た め に非 常 に大 き な 役 割 を も った 割 を 演 じ る こ と に な る.ま 物 質 で あ る こ とは 間 違 い な い.ま た,Nod る菌 体 外 多 糖 の生 成 が菌 の 感 染 に 関与 して い る こ と も知 factorは マ メ科 植 物 根 細 胞 の 根 粒 形成 に 関 す る 遺 伝 子(nodulin gene)を
Akiko Morikawa, Hiroshi Suzuki, Yuichi Sugiyama, E-mail : sugiyama@amol.f.u to kyo.ac.jp Multiplicity and molecular mechanism of substrate recognition by MRP 1) Cole, S.P., Bhardwaj, G., Gerlach,
Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing
Discovery, analysis and chemical mechanism of protein splicing VMA1 VMA1 2) Anraku, Y.: Genes to Cells, 2, 359-367 (1997) 3) Perler, F. B.: Cell, 92,1-4 (1998) 4) Perler, F. B.: Trends Biochem.
2007 Vol.56 No.6 総説 丸山浩樹
Reprinted from RADIOISOTOPES, Vol.56,.6 June 2007 Japan Radioisotope Association http : //www.jrias.or.jp/ α β α β ε m z α µ µ α m z m z µ µ Curr. Opin. Biotechnol J. Proteome Res Rapid Commun. Mass
Establishment and progress of Sendai virus engineering 2) Schnell, M. J., Mebatsion, T., Conzelmann, K.-K.: EMBO J., 13,4195-4203(1994) 3) Kato, A. et al.: Genes Cells, 1, 569-579 (1996) 4) Nagai,
VOL33NO.3/2010 A B A B p-erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 Erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 p-vasp VASP C D enos/gapdh x-fold vs sham 2.0 1.5 1.0 0.5 * 0 ANP (-) (+) (-)
.i...j...[.X8-2
Vol. 8 No.2 Nov. 2007 1 2 4 12 20 37 45 54 56 62 1 2 3 4 5 7 6 8 9 10 11 13 12 15 14 17 16 19 18 21 20 Hatena 23 22 Oidiodendron Oidiodendron 25 24 Monosiga ovata Monosiga 27 26 Toxoplasma gondii 29 28
64) M.L. Gefter, R.L. Russell: J. Mol. Biol., 39, 145 (1969) 65) F. Harada, F. Kimura and S. Nishimura: Biochim. Biophys. Acta., 182, 590 (1969) 65a) F.H.C. Crick: J. Mol, Biol., 19, 548 (1966); M. Nirenberg
Juntendo Medical Journal
The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical
分科会（OHP_プログラム.PDF
2B-11p 2B-12p 2B-13p 2B-14p 2B-15p 2C-3p 2C-4p 2C-5p 2C-6p 2C-7p 2D-8a 2D-9a 2D-10a 2D-11a 2D-12a 2D-13a 2E-1a 2E-2a 2E-3a 2E-4a 2E-5a 2E-6a 2F-3p 2F-4p 2F-5p 2F-6p 2F-7p 2F-8p 2F-9p 2F-10p 2F-11p 2F-12p
(Sinorhizobium melitoti )
ID ID INDE- TERMINATE (ID) /JST CREST E-mail : masayosicbiol. s.u-tokyo.ac.j p Systemic regulatory system sustaining symbiosis and organ development in legume (Sinorhizobium melitoti ) astray sunn nts
色覚（初組4）.pm
733 3 1 520 1 8 4 0.2500 1 30012 1 AB 3 22 3 1 2 http://www.nig.ac.jp/labs/devgen/mou.html 734 1.1 360nm 830nm 380nm 780nm 540nm 580nm 660nm 540nm 660nm Log relative corneal sensitivity 0 1 2 400 500 600
TRANSPORTSOME NEWSLETTER
TRANSPORTSOME QUARTERLY Winter 2009 1 2 3 4 5 6 Synaptobrevin, Synaptotagmin, rab3 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Dev Cell 2002, Curr Opin Cell Biol 2006, J Cell Biol 2008, Curr
Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo
Generation of neural cells from embryonic stem cells Takuya Yohei Okada Takahito Hideyuki Shimazaki Yoshizaki* Okano McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence
Database Center for Life Science Online Service
1) Araki, T.: Curr. Opin. Plant Biol., 4, 63-68 (2001) 2) Boss, P. K., Bastow, R. M., Mylne, J. S., Dean, C.: Plant Cell, 16, S18-S31(2004) 3) Simpson, G. G., Dean, C. : Science, 296, 285-289 (2002) 4)
Short Review Hidenori Takagi, Fumio Takaiwa, E-mail : takaiwa@nias.affrc.go.jp 13) Hirahara, K. et al. : J. Allergy Clin. Immunol., 102, 961-967 (1998) 14) Takagi, H. et al.: Proc. Natl. Acad. Sci.
The Heart Healthy Tocotrienol Complex Tocomin SupraBio
The Heart Healthy Tocotrienol Complex Tocomin SupraBio The Heart Healthy Tocotrienol Complex Tocomin SupraBio 1. Fact Sheet No. 317; World Health Organization (WHO), 2007 2. LLOYD-JONES D. et al. Circulation
Database Center for Life Science Online Service [Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome,
[Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome, Bunkyo-ku, Tokyo 113, Japan] [Graduate School of Agricultral Bioscien- ces, The University of Tokyo,
Refolding of proteins from inclusion bodies 1) Sunde, M., Blake, C. : Adv. Protein. Chem., 50, 123-159 (1997) 2) Goeddel, D. V., Kleid, D. G. et al. : Proc. Natl. Acad. Sci. USA, 76,106-110(1979)
76 3 B m n AB P m n AP : PB = m : n A P B P AB m : n m < n n AB Q Q m A B AQ : QB = m : n (m n) m > n m n Q AB m : n A B Q P AB Q AB 3. 3 A(1) B(3) C(
3 3.1 3.1.1 1 1 A P a 1 a P a P P(a) a P(a) a P(a) a a 0 a = a a < 0 a = a a < b a > b A a b a B b B b a b A a 3.1 A() B(5) AB = 5 = 3 A(3) B(1) AB = 3 1 = A(a) B(b) AB AB = b a 3.1 (1) A(6) B(1) () A(
/‚“1/ŒxŒ{‚×›î’æ’¶
60 1 pp.3-8 2010 1. H1N1 1) 2) 3) 4) ERATO 2009 H1N1 21 H1N1 HA PB2 2009 3 Pandemic H1N1 2009 WHO 6 11 21 2009 11 2010 4 21 H1N1 H1N1 2009 4 15 CDC 108-8639 4-6-1 TEL: 03-5449-5281 FAX: 03-5449-5408 E-mail:
2007050781......_.L.O...z.W
a s d f g a s d f g h j k l 0 in vitro in vivo in vitro in vivo in vivo in vivo in vitro Metabolism Metabolism Endocr Endocr Endocrinol Ann NYA cad Sci J clin Endocr Metab
Biology of spermatogenesis and spermatozoa in mammals. Biophys. Biochem. Cytol. Arch. Biochem. Biophys. Anat. Rec. Biol. Reprod. Mol. Hum. Reprod. Biol. Reprod. Reprod. Biol. Endocrinol. Aust. J. Zool.
1...z04/08/.e2
August 2004 29 α α 30 Functional Glycomics News Letter No.4 α α August, 2004 31 β ü β α β α 32 Functional Glycomics News Letter No.4 α β August, 2004 33 34 Functional Glycomics News Letter No.4 α β ü August,
会誌71
ATP * ATP γ γ 2 ATPC1 ATPC2ATPC2 ATPC2 ATPC1 ATP ATP 1. ATP ATP ATP ATP ATP F o F1 2 1) 1 ATP Trx γ ATP CFoCF1 ATP γ 2 Cys 2) 2 γ γ 3,4) ATP -γ 2 ATPC1 ATPC2 At4G04640, At1G15700 73 20 5) ATPC2 6) ATPC2
M. mobile M. mobile
Short Review Mycoplasma mobile Mycoplasma mobile http : //www. geocities.co.j p/technopolis/1721/myco.htm Makoto Miyata, E-mail : miyata(sci.osaka-cu.ac.jp http://www.geocities.co.jp/technopolis/1721/myco.htm
Vol.53 No. 11 (2008) 1327
Molecules that regulate morphology of the plasma membrane Shiro Suetsugu, Kazunori Takano E-mail : suetsugu@iam.u-tokyo.ac.jp 1326 Vol.53 No. 11 (2008) Vol.53 No. 11 (2008) 1327 1328 Vol.53 No. 11 (2008)
Review Column 1) Extavour, C. G., Akam, M. : Development, 130, 5869-5884 (2003) 2) Saitou, M. et al.: Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358,1363-1370(2003) 3) Eddy, E. M. : Int. Rev.
:010_ :3/24/2005 3:27 PM :05/03/28 14:39
:010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28 14:39 :010_896300101703 :3/24/2005 3:27 PM :05/03/28
Database Center for Life Science Online Service Vol.48 No.16 (2003)
Database Center for Life Science Online Service Key words Kikuya Kato, E-mail : kkato@bs.aist-nara. ac.jp http://love2.aist-nara.ac.jp Shin Ishii, E-mail : ishii@is.aist-nara.ac.jp http://hawaii.aist-nara.
Database Center for Life Science Online Service
2) Shin, S. I., Fredman, V. H., Risser, P., Pol lack,r.: Proc. Natl. Acad. Sci. USA, 72, 4435-4439 (1975) 3) Marquardt, H., Todaro, G. J.: J. Biol. Chem., 256, 6859-6865 (1981) 4) Dicker, P., Pohjanpelto,
肺癌第50巻第4号
1 Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan; 2 Department of Thoracic Surgery, Aichi Cancer Center, Japan;
1) P. Nurse, P. Thuriaux & K. Nasmyth: Mol. Gen. Genet., 145, 167 (1976). 2) R. Ohi, C. McCollum, B. Hirani, G.J. Den Hasse, X. Zhang, J.D. Burke, K. Turner & K.L. Gould: EMBO J., 13, 471 (1994). 3) T.
ü β 93
Amyloid Fibril Formation and Protein Science Yuji GOTO Institute for Protein Research, Osaka University E-mail: ygoto@protein.osaka-u.ac.jp Abstract: Amyloid fibrils have been a critical subject in recent
本文／ＹＡ９２５５Ｆ
pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department
Database Center for Life Science Online Service
10) Shinagawa, H., Kato, T., Ise, T., Makino, K., Acad. Sci. USA, 82, 4336-4340 (1985) Sci. USA, 85, 1811-1815 (1988) 19 zwoodgate, R., Rajagopalan, M., Lu, C., Echols, H.: Proc. Natl. Acad. Sci. USA,
D., Nicola, N. A., Hilton, D. J.: Nature, 387, 917-921 (1997) 12) Alexander, W. S. : Nat. Rev. Immunol., 2,410-416 (2002) 13) Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P., Shuai, K. : Science,
Database Center for Life Science Online Service
図8SINEの SINEと3'末 親 と な って い るLINEの 系 統 関係 端 を共 有 して い るLINEは 赤 色 で 示 す, 報 告 さ れ て い るす べ て のLINEは11の ら れ る.そ れ ぞ れ のLINEの グル ー プ に分 け あ い だ にお い て 水 平 的 な交 流 が な い と仮 定 す る と,こ の11に 分 け られ る こ のLINE え
[Department of Pediatrics, Gifu University School Clinical. Pathological and Biochemical Abnormality in peroxisomal Disorders 1) Goldfischer, S., Moore, C. L., Johnson, A. B., Spiro, A. J., Valsamis,
Short Review Database Center for Life Science Online Service bicoid oskar mrna. gurken mrna bicoid mrna Tamaki Yano,
Short Review bicoid oskar. gurken bicoid Tamaki Yano, E-mail : tyanoc@mail.pharm.tohoku.ac.jp Maternal RNA localization and RNP-complex, essential for the polarization of the oocyte in Drosophila hunchback
(a) (b) (c) (d) 1: (a) (b) (c) (d) (a) (b) (c) 2: (a) (b) (c) 1(b) [1 10] 1 degree k n(k) walk path 4
![(a) (b) (c) (d) 1: (a) (b) (c) (d) (a) (b) (c) 2: (a) (b) (c) 1(b) [1 10] 1 degree k n(k) walk path 4](/thumbs/91/105665060.jpg "(a) (b) (c) (d) 1: (a) (b) (c) (d) (a) (b) (c) 2: (a) (b) (c) 1(b) [1 10] 1 degree k n(k) walk path 4")
1 vertex edge 1(a) 1(b) 1(c) 1(d) 2 (a) (b) (c) (d) 1: (a) (b) (c) (d) 1 2 6 1 2 6 1 2 6 3 5 3 5 3 5 4 4 (a) (b) (c) 2: (a) (b) (c) 1(b) [1 10] 1 degree k n(k) walk path 4 1: Zachary [11] [12] [13] World-Wide
Microsoft Word _abstract_kasai_ikeya2_tk.docx
科学研究費補助金新学術領域研究 スパースモデリングの深化と高次元データ駆動科学の創成 最終成果報告会 (207/2/8-20) NMR (NMR) NMR! SpM NMR NMR NMR (MaxEnt) (CS) NMR (SpM) NMR NMR ( ) 2 NMR NMR 2 NMR NMR NMR n n- 2 NMR E-mail: kigawa@riken.jp 2 (non-uniform
1) Ogawa, H., Lazarus, G. S., Hopsu-Havu, K.: The Biological Role of Proteinases and their Inhibitors in Skin, Univ. Tokyo Press (1985) 2) Sottrup-Jensen, L., Stepanik, T. M., Kristen sen,t., Wierzbicki,
感 染 症 にお ける 細 胞 貪 食 の 役 割:宿 主と微生物の攻防 食細胞による微生物の取 り込みと殺菌 水上令子 武谷 立 住本英樹 細 菌や真菌が食細胞内 に取 り込 まれ るときに は,ま ず細胞表面 の受 容体 によ って微生 物が認 識 される.こ の食 作用受容体の下流で起 こるシグナル伝達 によ り,微 生物 を内部 に取 り込 んだ 食 胞 が細 胞内に形成される.食 胞は成熟の過程
Modiolus squamosus M. d. granosissimus(=geukensia demissa= M. demissus) Noetia ponde- rosa J.M.: J. Exp. Zool. 215: 277-287 (1981) 9) Bowlus, R.D. & Somero, G.N.: J. Exp. Zool. 208 : 137-152 (1979)
その科学と技術 No.48( )
45 CI +,,* a-, +0 a-, +0 a-, +., a-, + +, - +, CD CF - CTS CD a-cd b-cd g-cd a- +., 0 1 2 - +33-. CI CI CD CD a- +., CI a- +0, CD Bacillus circulans T--*.*. 13 a-, +0 CI-1 CI-2. CI-3 +* / CI 0 CI-1 CI-+1
Database Center for Life Science Online Service Natuo Komoto, jp Silkworm mutants
Natuo Komoto, E-mail : natuo@affrc.go. jp http://cse.nias.affrc.go.jp/natuo/index.htm Silkworm mutants whose deficiency of epidermal orate granules causes translucent larval skin phenotypes 図3 カイ コ幼 虫
本文／ＹＡ７２６１Ｅ
J. Cell Biol.,,. Segev, N.Curr. Opin. Cell Biol.,,. Lafont, F., Lecat, S., Verkade, P., & Simons, K.J. Cell Biol.,,. Mostov, K.E., Verges, M., & Altschuler, Y.Curr. Opin. Cell Biol.,,. Sato, T., Mushiake,
Makoto Onoda, Department of Anatomy and Cell Biology, Georgetown University School of Medicine, 3900 Reservoir Road, N. W., Washington, D. C. 20007, USA Regulation Mechanism of Spermatogenesis : Cell-to-cell
46 12 3 1 ATP ( ) ATP ~P 1~P hyd Gº 1 1 1950 ~P hyd Gº Hansia et al. Biophys Chem 119: 127, 2006 ~P hyd Gº 1? ATP hyd Gº ATP ATP ATP ~P ε ~P George [BBA 223: 1, 1970] ~P 2) hyd Gº 1. ph Mg 2+ 2. 1 2 2
45 セ ル ラ ー ゼ複 合 体 セ ル ロソ ー ム の構 造 と機 能 III.C.thermocellumの 1.セ セ ル ロ ソー ム ル ロソーム の概 念 セ ル ロソー ム は,は じめC.thermocellumの 細 胞 をセ ル ロ ー ス へ 結 合 させ る た め の セ ル ロ ー ス 結 合 因 子 と し て 見 い だ さ れ た が,こ れ が 多 数 の セ
ARE : AU-rich element eef1a : eukaryotic elongation factor 1A eif : eukaryotic initiation factor erf : eukaryotic releasing factor NMD : nonsense-medi
Regulation of mrna decay in eukaryote ARE : AU-rich element eef1a : eukaryotic elongation factor 1A eif : eukaryotic initiation factor erf : eukaryotic releasing factor NMD : nonsense-mediated mrna decay
Technical Bulletin TransFast TM Transfection Reagent E /
Technical Bulletin TransFast TM Transfection Reagent E2431 http://www.promega.com/tbs/tb260/tb260.pdf / www.promega.co.jp 2006 8 TransFast TM Transfection Reagent E2431 I....................................................................
Ｖｏｌ．４０ Ｎｏ．５△／△０ 目次［三］１０．２３
! Department of Management, Miyagi University, 2 2 1 Hatatate Taihaku-ku Sendai, Miyagi 982 0215 Industrial Technology Institute, Miyagi Prefectural Government, 2 2 Akedoori Izumi-ku Sendai, Miyagi 981
Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati
![Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati](/thumbs/99/141742304.jpg "Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati")
School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferation and Activation Mechanism of GTP Binding Proteins by the Enzyme 3) Nishizuka, Y.: Nature,
住まい・まちづくり活動事例集
3 H15 1982 1988 5 H16.31 1 1 1 246 26 3 2003 11 21,417/ 65 17.91% 16.62%1.29 246 2 1 12 1246 5008026 30080 3 200803 120060 2 20013 1 1 21 11 19821988 199112003 13 1988 1 1991 28 3 1991 1993 1992 1 1995
Review Database Center for Life Science Online Service Streptomyces verticillus Streptomyces verticillus Molecular mechanisms for bleomycin res
Review Streptomyces verticillus Streptomyces verticillus E-mail Molecular mechanisms for bleomycin resistance : sugi(c~hiroshima-u.ac.jp Klebsiella 1) Umezawa, H., Maeda, K., Takeuchi, T., Akami,
5200) [Department of Biochemistry, Miyazaki Medical College, Kihara, Kiyotake-cho, Miyazaki 889-16, Japan] Natriuretic Peptide Family: ANP and BNP 1) de Bold, A. J.: Science, 230, 767-770 (1985)