VITAMIN _R21172(高解像度).pdf

Size: px
Start display at page:

Download "VITAMIN _R21172(高解像度).pdf"

Transcription

1 AREDS I AREDS I AMD AREDS I AMD AMD AREDS I DHA EPA AMD AREDS II AREDS II GRAS Generally Recognized as a Safe FAO/WHO JECFA 1 2 mg/kg 2006 OSL Observed Safety Level 20 mg/ 3 C40H56O Eye Disease Case-Control Study EDCCS / 6 mg/ AMD 43 AMD Lutein Antioxidant Supplementation Trial LAST AMD 90 MPOD Macular Pigment Optical Density Age-Related Eye Disease Study1 AREDS1 AMD Tagetes erecta Linne 80-3 LCPFA

2 AREDS / 10 mg/ 2 mg/ -3 LCPFA 1 g/ / 3 AREDS1 3 AMD AMD AREDS II AREDS AMD 1 2 AREDS II AREDS1 AREDS AMD Centrum Silver 0.275mg AREDS DHA EPA 2 AREDS AREDS AMD AMD AMD / DHA EPA AREDS1 AMD AREDS - AREDS AMD AREDS 3 AMD AREDS 3 AMD 25 1 AMD

3 AREDS / AREDS / DHA/ EPA AREDS DHA/EPA AREDS / AREDS AMD 10 AREDS DHA/EPA AMD AREDS AMD 26HR 0.74 P vs. / - AREDS / - AREDS AREDS - 2 3

4 O2 3 O / AMD 18HR 0.82 p AREDS FGL / AREDS AMD 10 AREDS II 10 mg/ 2 mg 1 AREDS II C 500 mg E 400 IU / 10 mg/2 mg 80 mg 2 mg O StARD3 20 GSTP1 S- Pi GSTP1 21 StARD nm 446 nm 22 ROS 23 24

5 in vitro in vivo AMD / ips 1 AMD Key Words AREDS II (Age-Related Eye Diseases Study II), AMD (Age-Related Macular Degeneration), Randomized Clinical Trial, Lutein, Zeaxantin 1 The General Incorporated Association of International Foods & Nutrition (AIFN) Chief Executive Of cer 2 Kemin Japan KK Representative Director Kazuo Sueki 1, Masafumi Hashimoto 2 1 AIFN Chew E, Age-Related Eye Diseases Study II Research Group. AREDS II. Retina, Subspecialty Day 5-6, Clinical Studies Database. Age Related Eye Diseases Study II (AREDS II). Last update 2/3/2006. pp Alves-Rodrigues A, Shao A (2004) The Science Behind Lutein, Toxicol Lett 150, Stahl W, Sies H (2003) Antioxidant activity of carotenoids. Mol Aspect Med 24, Semba RD, Dagnelie G (2003) Are lutein and zeaxanthin conditionally essential nutrients for eye health? Med Hypotheses 61, Stahl W, Sies H (2005) Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta 1740, De Spirt S, Lutter K, Stahl W (2010) Carotenoids in photooxidative stress. Curr Nutr Food Sci 6, Semba RD, Dagelie G (2003) Are lutein and zeaxanthin conditionally essential nutrients for eye health? Med Hypotheses 61, Stahl W, Sies H (2005) Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta 1740, De Spirt S, Lutter K, Stahl W (2010) Carotenoids in photooxidative stress. Curr Nutr Food Sci 6, Stahl W, Sies H (2003) Antioxidant activity of carotenoids. Mol Aspects Med 24, Stahl W, Sies H (2005) Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta 1740, Stahl W, Sies H (2003) Antioxidant activity of carotenoids. Mol Aspects Med 24, Kim SR, Nalanishi K, Itagaki Y, Sparrow JR (2006) Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res 82, Thammanina GSS, Dinesha R, Harsha R, Srinivas L (2010) Free radical scavenging activity of lutein - isolated from methi leaves (Trigonella foenum graecum). Int J Pharm Pharm Sci 2, Trevithick-Sutton CC, Foote CS, Collins M, Trevthick JR (2006) The retinal carotenoids zeaxanthin and lutein scavenge superoxide and hydroxyl radicals: A chemiluminescence and ESR study. Mol Vis 12, Landrum JT, Bone RA (2001) Lutein, zeaxanthin, and the macular pigment. Arch Biochem Biophys 385, Khachik F, Bernstein PS, Garland DL (1997) Identi cation of lutein and zeaxanthin oxidation products in human and monkey retinas. Invest Ophthalmol Vis Sci 38, Li B, Vachali P, Berstein PS. (2010) Human ocular carotenoidbinding proteins. Photochem Photobiol Sci 9, Bhosale P, Berstein PS (2005) Synergistic effects of zeaxanthin and its binding protein in the prevention of lipid membrane oxidation. Biochim Biophys Acta 1740, SnoeeerlyDM, Brown PK, Delori FC, Auran JD (1984) The macular pigment. I. Absorbance spectra, localization, and discrimination from other yellow pigments in primate retinas. Invest Ophthalmol Vis Sci 25, Krinsky NI, Landrum JT, Bone RA. (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Ann Rev Nutr 23, Semba RD, Dagnelie G (2003) Are lutein and zeaxanthin condi-

6 tionally essential nutrients for eye health? Med Hypotheses 61, Krinsky NI, Landrum JT, Bone RA (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Ann Rev Nutr 23, Stahl W, Sies H (2003) Antioxidant activity of carotenoids. Mol Aspects Med 24, Kim SR, Nakanishi K, Itagaki Y, Sparrow JR (2006) Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Rye Res 82,

新旧対照表 版番号あたり 変更箇所 旧 新 1 表面 ) はさみマーク 点線 チャックマーク 削除 2 裏面 ) はさみマーク 点線 開封後はチャックを閉じて保存してください チャックマーク 5mm 下げる 3 届出番号 - A102 4

新旧対照表 版番号あたり 変更箇所 旧 新 1 表面 ) はさみマーク 点線 チャックマーク 削除 2 裏面 ) はさみマーク 点線 開封後はチャックを閉じて保存してください チャックマーク 5mm 下げる 3 届出番号 - A102 4 新旧対照表 1 2 3 4 7 5 版番号あたり 0-0000-0-0000-00 6 変更箇所 旧 新 1 表面 ) はさみマーク 点線 チャックマーク 削除 2 裏面 ) はさみマーク 点線 開封後はチャックを閉じて保存してください チャックマーク 5mm 下げる 3 届出番号 - A102 4 左右に余白をとるため文章の配置変更 文字の配置を変更 5 位置変更 JAN コード 3mm 上げる

More information

040202PC用.doc

040202PC用.doc 15 48 15 8 25 15 1321 15 8 25 0825002 15 8 25 6 8 15 2 18 15 6 27 2 15 3 13 28 35 (1) 51 198 7 (2) 3 6 1 100g (1) 1 (1) 1 2 1 astaxanthin;3,3 -dihydroxy-, -carotene-4,4 -dione (2) 1 2 C40H52O4 596.86 97.0

More information

untitled

untitled ORYZA POLYAMINE ORYZA POLYAMINE -P -PC -LC 1. Ver.1.0 MM ver. 1.0MM 1) Roseeuw D.I. et al., Epidermal keratinocytes actively maintain their intracellular polyamine levels. Cell Tissue Kinet. 16, 493-504

More information

The Heart Healthy Tocotrienol Complex Tocomin SupraBio

The Heart Healthy Tocotrienol Complex Tocomin SupraBio The Heart Healthy Tocotrienol Complex Tocomin SupraBio The Heart Healthy Tocotrienol Complex Tocomin SupraBio 1. Fact Sheet No. 317; World Health Organization (WHO), 2007 2. LLOYD-JONES D. et al. Circulation

More information

J Life Sci Res 2014; 12: Osaka Prefecture University Journal of Life Science Research Online ISSN

J Life Sci Res 2014; 12: Osaka Prefecture University Journal of Life Science Research Online ISSN J Life Sci Res 2014; 12: 15-19 2014 Osaka Prefecture University Journal of Life Science Research Online ISSN 2186-5809 583-8555 3-7-30 577-8567 3-1-1 2014 9 11 2014 10 21 Exposure mild-level LED light

More information

2007050781......_.L.O...z.W

2007050781......_.L.O...z.W a s d f g a s d f g h j k l 0 in vitro in vivo in vitro in vivo in vivo in vivo in vitro Metabolism Metabolism Endocr Endocr Endocrinol Ann NYA cad Sci J clin Endocr Metab

More information

食糧 その科学と技術 No.48( )

食糧 その科学と技術 No.48( ) 79 +.* + 1/* A + 80, E + + Bioaccessibility +, 81,. 0* nm bo, Caco-, +* - - 82 - Caco, + Pow +, b-carotene ;,, a-carotene ; -, b-cryptoxanthin ;., lutein ; /, zeaxanthin ; 0, canthaxanthin ; 1, astaxanthin

More information

日本皮膚科学会雑誌第122巻第2号

日本皮膚科学会雑誌第122巻第2号 J Dermatol Sci Vitam Horm NEnglJMed Lancet J Clin Invest Antitoxid Redox Signal Diabetes Metab Res Rev Diabetes Care Diabet Med Diabetes care Diabetes Care J Foot Ankle Surg Wound Repair Regen Lancet Foot

More information

比較眼科研究 第30巻

比較眼科研究 第30巻 Anim. Eye Res. Brief Note Application of Optical Coherence Tomography (OCT) for Ophthalmologic Examination in Cynomolgus Monkeys Tomoaki ARAKI, Arisa HIGASHI, Koji KABAYAMA, Takayuki ICHI, Haruna NAGAE

More information

感覚系における人工臓器 ─人工網膜

感覚系における人工臓器 ─人工網膜 人工臓器 最近の進歩 Hiroyuki KANDA, Takashi FUJIKADO 1. はじめに 2. 視覚のなり立ち 図 1 10 著者連絡先 565-0871 2-2 E-mail. kanda@sensory.med.osaka-u.ac.jp 1 3. 視覚障害 Quality of Life QOL 2 1 1 12 18 1 25.5 2 21.0 3 8.8 1) 1 51 New

More information

日本皮膚科学会雑誌第121巻第11号

日本皮膚科学会雑誌第121巻第11号 β Clin Rheumatol Arthritis Rheum Am J Cardiol J Rheumatol J Rheumatol Arthritis Rheum Arthritis Rheum Arthritis Rheum Rheumatology Oxford Rheumatology Oxford Br J Dermatol Arch Dermatol Ann Rheum Dis

More information

% 1% SEM-EDX - X Si Ca SEM-EDX SIMS ppm % M M T 100 % 100 % Ba 1 % 91 % 9 % 9 % 1 % 87 % 13 % 13 % 1 % 64 % 36 % 36 % 1 % 34 46

% 1% SEM-EDX - X Si Ca SEM-EDX SIMS ppm % M M T 100 % 100 % Ba 1 % 91 % 9 % 9 % 1 % 87 % 13 % 13 % 1 % 64 % 36 % 36 % 1 % 34 46 Review on Hair Analysis in the Wakayama Arsenic Case Jun KAWAI Department of Materials Science and Engineering, Kyoto University Sakyo-ku, Kyoto 606-8501, Japan Received 6 December 2014, Revised 29 December

More information

2 はじめに 健康食品をめぐる問題点 a) 有効性に関する問題点 4 HPLC HPLC 3 CoQ10

2 はじめに 健康食品をめぐる問題点 a) 有効性に関する問題点 4 HPLC HPLC 3 CoQ10 1 総 説 健康食品をめぐる問題と展望 長村 洋一 キーワード : DSHEA 要旨 6 2 はじめに 6 26 1 8 20 1 2 3 1. 健康食品をめぐる問題点 a) 有効性に関する問題点 4 HPLC HPLC 3 CoQ10 3 図 1 市販されている健康食品の含有量の実態 ( 国民生活センターのホームページより ) b) 安全性に関する問題点 17 18 4 18 4 5 - - -

More information

日本皮膚科学会雑誌第122巻第7号

日本皮膚科学会雑誌第122巻第7号 Br J Dermatol NEnglJ Med 尋常性白斑診療ガイドライン 図 1 先天性白斑 白皮症の病型分類 図 2 後天性白斑 白皮症の病型分類 の尋常性白斑患者で家系内発症がみられることより 3 5 れらの合併が染色体 17p13 における一塩基多型に起 非分節 因し その候補遺伝子の一つが自然免疫に重要とされ 型に含まれる汎発型には甲状腺に対する抗サイログロ る NALP1 遺伝子であると報告している6

More information

t 492 t mg/l 30 mg/l BOD 95 OH = cm 3 / sec 25 8 OH /cm 3 12 = ph ph

t 492 t mg/l 30 mg/l BOD 95 OH = cm 3 / sec 25 8 OH /cm 3 12 = ph ph 2-1 200169 2740 CAS 110-49-6 1103 2- O H 3 C C O CH 2 CH 2 O CH 3 C 5 H 10 O 3 118.13 200168 2-1 99 2-1. 2 2, 3-65 2, 3 144145 45 o.c. 3 392 3 1.512.3 d19 1.009 2 4.07 = 1 30 Pa 0.23 mmhg20 2 4 log Pow0.10

More information

寄稿論文 高い発ガン活性を示す鉄キレートお構造特性 | 東京化成工業

寄稿論文 高い発ガン活性を示す鉄キレートお構造特性 | 東京化成工業 NTBI = nontransferrin-bound iron NTBI DNA H DNA 2 NTBI NTBI NTBI NTBI NTBI NTBI (nta) (nta) (nta) NTBI (nta) (nta) NTBI (nta)ntbi Fe-(nta) (nta) N(CH 2 CH) 3 HCCH 2 NHCH 2 CH 2 NHCH 2 CH (HCCH 2 ) 2 NH

More information

5) Kawada T, Hagihara K, Iwai K (1986) Effects of capsaicin on lipid metabolism in rats fed a high fat diet. J Nutr 116 : 1272-8. 6) Kawada T, Watanabe T, Takaishi T, Tanaka T, Iwai K (1986) Capsaicin-induced

More information

なるほどルテイン ~AREDS2編①(2013年5月5日発表分)~

なるほどルテイン ~AREDS2編①(2013年5月5日発表分)~ まずは 1 おさらい 加齢性眼疾患研究 () は 米国連邦政府の国立衛生研究所のひとつである国立眼科研究所が 資金を提供して実施した大規模臨床試験です 目的 AMD と白内障の臨床経過 発症と危険因子の評価 AMD と視力損失の進行における 高用量の抗酸化剤と亜鉛の有用性を評価白内障と視力損失の発症と進行における 高用量の抗酸化剤の有用性を評価 デザイン大規模な多施設 無作為 前向き プラセボ対照

More information

資料1(目消し版).ppt

資料1(目消し版).ppt 1 Dr. Grandjean 2 15 45 3 4 CH 3 Hg + Hg 0 fi Hg ++ fich 3 + MeHg MeHg 5 Methylmercury-2 6 :, A. Yasutake 7 - A. Yasutake 8 :,. A. Yasutake 9 A. Yasutake 10 (%) : : : : : MeHg 0.05 250 : 2 : 1 : 0.1 :

More information

bc0710_010_015.indd

bc0710_010_015.indd Case Study.01 Case Study.02 30 Case Study.05 Case Study.03 Case Study.04 Case Study.06 Case Study.07 Case Study.08 Case Study.21 Case Study.22 Case Study.24 Case Study.23 Case Study.25 Case Study.26

More information

日本皮膚科学会第121巻第9号

日本皮膚科学会第121巻第9号 Appl Nurs Res Wound Repair Regen Int Wound J Adv Skin Wound Care Ostomy Wound Manage Wound Repair Regen Int J Nurs Stud JAdvNurs Visual Dermatology J Adv Nurs Appl Nurs Res Cochrane Database Syst Rev

More information

et al No To Shinkei Clin Neurol Neurology et al J Neurosurg et al Arch Neurol et al Angiology

et al No To Shinkei Clin Neurol Neurology et al J Neurosurg et al Arch Neurol et al Angiology 37 Recommendations for the Management of Moyamoya Disease A Statement from Research Committee on Spontaneous Occlusion of the Circle of Willis (Moyamoya Disease) Research on intractable diseases of the

More information

本文.indd

本文.indd 35 1 2013 4 Reprinted From THE RESEARCH BULLETIN OF THE FACULTY OF EDUCATION AND WELFARE SCIENCE, OITA UNIVERSITY Vol. 35, No. 1April 2013 OITA, JAPAN Res. Bull. Fac. Educ.Welf. Sci., Oita Univ. 17 7 3

More information

立命館21_松本先生.indd

立命館21_松本先生.indd 2143-552010 1 2 () 1 2 3 456 78- Key Words 1 3 12007 2 3 508 19992008 1 23 4 43 2120107 4 2008 1992 2003 2005 1989 2008 4 2 2-1 10 4 4 6 5 4 5 2946 1 155 11 41 44 45 4 2-2 2003 1 21 2 1 3 4 5 6 7 3 2120107

More information

立命館20_服部先生.indd

立命館20_服部先生.indd 20 93-105 2010 2 () ' - 1 ( ) ( ' 2005) Key Words 2 1967 93 20 2010 1 94 1 ' 2002 2 2 1996 1996 1999 2 2 2 1993 1999 4 1 2 1985 1989 1986 1994 4 1 2 1 1 4 2 4 4 1 4 1966 4 10-1970 20 1993-1972 95 20 2010

More information

1996 2000 2004 1984 2005 7150 000 9 500 9 4 13 10 95 11 11 12 20002004 9 70

1996 2000 2004 1984 2005 7150 000 9 500 9 4 13 10 95 11 11 12 20002004 9 70 14 2006 1 Key Words 2002 3 1 2 3 3 1 2 3 1969 1987 69 1996 2000 2004 1984 2005 7150 000 9 500 9 4 13 10 95 11 11 12 20002004 9 70 14 2006 1 15 71 72 1 22 6 32 9 200 6 3 1 2 2000 10 1 2003 10 2005 6 5 4

More information

立命館16_坂下.indd

立命館16_坂下.indd 1669-792008 1 - ' 85- -108 ' Key words 1 2 2003 69 1620082 5 3 1990 1997 4 5 2001 1307 6 7 1 1 1 1996 100 2 1997 71 3 1998 71 4 1999 96 5 2000 95 6 2001 145 7 2002 191 8 2003 174 9 2004 120 10 2005 122

More information

立命館人間科学研究No.10

立命館人間科学研究No.10 1 77 5 Key words 1 23 3 11417 14310045 20022004 2 2003 20022005 20022004 2 10200511 3 2003 1152003 59 1995 3 32003 19932002 20032003 2005 20052005 4 1997 2000521986 2001 42001 3 1981 6 1 7 5 1000248 1632647

More information

立命館21_川端先生.indd

立命館21_川端先生.indd 21 119-132 2010 ( ) ' Key Words 119 21 2010 7 1962 2001 2001 2007 1982 1988 1997 2007 1997 1998 1863 1880 1 1998 1998 2001 1599 120 121 1599 1695 8 1695 1714 4 1714 1715 5 1715 100 1812 9 1812 1864 2001

More information

立命館14_前田.indd

立命館14_前田.indd 1499-1122007 1 ) ) ) ) ) (1) -- ) ) ) ) ) ) ( ) ) ' ) ) ) ) - 1) 2)' 3) Key words 19811994 1721 99 1420073 100 20012004 2005 2004 2002 33 34 10 1987 45 20002003 2002 1 1 2000 1 1 2001 2 200341 12004 2

More information

立命館17_坂下.indd

立命館17_坂下.indd 1793-1052008 1 () -- -- - Key words 1 93 1720088 2 3 2003 15 1996 50 3040 2 3 4050 50 10 1980 1995 1950 1958 1968 1972 94 95 1987 4 4 70 3 3 1 2000 2001 4 1720088 96 2001 2003 2 1978 1990 1997 130 2 3

More information

立命館人間科学研究No.10

立命館人間科学研究No.10 49 00 7 Key words 980 995 50 0005 90 997 99 990 994 99 99 99990 99 996 988988 994 99 995 995 995 994 984 988 986 997 997 00 995 00 5 7 5 5 999 997 997 998 6 998 999 997 997 998 0040000 994 996 000 00 5

More information

立命館19_椎原他.indd

立命館19_椎原他.indd 191-132009 1 ( ) ' Key Words 1 11 12007 2007 200520062 201120062 7558 4009 1 1920098 2007 2 2000 028 2005 1999 12 1999 13 1968 2 3 '1992 2007 2001 20052001 1977 2005 2005 2007 21 21 22 461927 3 13 1920098

More information

立命館人間科学研究No.10

立命館人間科学研究No.10 61 10 1990 Key words 1 102005 11 62 2000 1 1920 10 1892 63 1 1 19 100 1914 100 1 1 20 1 2 102005 11 64 1946 21 4 1947 1949 1947 22 1 3 1956 1959 1958 2 1964 65 2 10 1975 7080 70 2 1 1987 1990 40 1989 1989

More information

立命館19_徳田.indd

立命館19_徳田.indd 1991-1022009 1 2 () )--) 28 2827 1 2 Key Words 1 (1721 2000 20012001 20082009 91 1920098 92 20042004 2004 2001 12 2005 20082009 2005 3 1997 200820096 2007 2 20082009 93 20012001 12 2008 2009 19611966 1

More information

1 P2 P P3P4 P5P8 P9P10 P11 P12

1 P2 P P3P4 P5P8 P9P10 P11 P12 1 P2 P14 2 3 4 5 1 P3P4 P5P8 P9P10 P11 P12 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 & 11 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1! 3 2 3! 4 4 3 5 6 I 7 8 P7 P7I P5 9 P5! 10 4!! 11 5 03-5220-8520

More information

日本感性工学会論文誌

日本感性工学会論文誌 pp.343-351 2013 Changes in Three Attributes of Color by Reproduction of Memorized Colors Hiroaki MIYAKE, Takeshi KINOSHITA and Atsushi OSA Graduate School of Science and Engineering, Yamaguchi University,

More information

10中西_他.indd

10中西_他.indd Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab

More information

VOL. 17 NO. 7 CHEMOTHERAPY 1305 1) W. BRumFirr et al. : Clinical and laboratory studies with carbenicillin. Lancet 1: 1289~ 1293, 1967 2) E. T. KNUDSEN et al. : A new semisynthetic penicillin active against

More information

11 12 13 14 102 102 102 83 39 38 37 31 141 140 139 114 (1) 14 17/23(73.9% 9 ) 651/660(98.6%) (2) 14 9 356 (3) 1,200 1,000 100 100 (4) 1,600 2,000 (5) 14 8 (6) 10,633 8,308 (7) 14 14 660 14 383 14 14 1,043

More information

46 12 3 1 ATP ( ) ATP ~P 1~P hyd Gº 1 1 1950 ~P hyd Gº Hansia et al. Biophys Chem 119: 127, 2006 ~P hyd Gº 1? ATP hyd Gº ATP ATP ATP ~P ε ~P George [BBA 223: 1, 1970] ~P 2) hyd Gº 1. ph Mg 2+ 2. 1 2 2

More information

2

2 2 3 4 5 6 7 8 9 1 2 3 4 5 10 11 12 1 2 1 2 1 2 13 14 3 17 15 1 2 3 D Usefulness of Tc-99m MIBI SPECT in predicting multidrug resistance gene expression level in non-small cell lung cancer a preliminary

More information

Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,

More information

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Journal Physiology, American Journal of Physiology, Journal of Physiology, Journal of Autonomic Nervous System, American Journal of Physiology,

More information

201609発達・教育臨床論コース

201609発達・教育臨床論コース 葛 葛 遡 ONISHI Kimie 1971 7 14 2013 4 1900-30 2013 4 2013 4 2013 4 1950 2009 6 4 1 257-288 2012 3 4 145-187 2013 3 1 16-39 5 84-107 7 368-383 18 2008 8 80-85 100 18330178 2009 3 223-248 1930 20530686

More information

2001 2003 2005 2006 2007 2008

2001 2003 2005 2006 2007 2008 2001 2003 2005 2006 2007 2008 60 etc. http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm 23.5% 2.8% 2.8% 3.4% 30.3% 9.9% 11.5% 15.8% AAN 65

More information

Rinku General Medical Center

Rinku General Medical Center Rinku General Medical Center 4860 100 1620 Ann Intern Med. 1966; 64: 328 40 CHOP 63 1 83 J Clin Oncol. 1998; 16: 20065-69 Febrile Neutropenia IDSA(Infectious Diseases Society of America) 2002 Guidelines

More information

研究成果報告書

研究成果報告書 21 5 28 2007 2008 CARElk CARPXR CAR CAR EST cdna CAR CAR 10FCS 96 SW480 HepG2 anti-lamin A/C anti-phospho-histone H3 anti-cyclin D1 G1 anti-cyclin A S CAR lamin A/C CAR Fig. 1 Lamin A/C /G1 lamin A/C G1

More information

5) Corn meal Agar Corn meal @ 40 Agar @ 20 6) Corn Meal Blood Agar 7) Agar 8) Blood Agar Saccharide @ 30.0 NaNO3 @ 2.0 K2HPO4 @ 1.0 MgSO47H2O @ 0.5 KC1 @ 0.5 F2SO47H2O @ 0.01 Agar @ 30.0 11) Mueller Hinton

More information

Effect of Supplementation of Sulfur-Containing Amino Acids to a Low-Soy Protein Diet Containing Cholesterol on Plasma Cholesterol Levels in Rats Tokik

Effect of Supplementation of Sulfur-Containing Amino Acids to a Low-Soy Protein Diet Containing Cholesterol on Plasma Cholesterol Levels in Rats Tokik Effect of Supplementation of Sulfur-Containing Amino Acids to a Low-Soy Protein Diet Containing Cholesterol on Plasma Cholesterol Levels in Rats Tokiko MIZUNO, Hiroko ABE, Ryuji HIRANO and Koji YAMADA

More information

History I COE

History I COE 2008 108-8641 5-9-1 TEL 03-5791-6334FAX 03-5791-6335 e-mailgakufu@lisci.kitasato-u.ac.jp 228-8555 1-15-1 TEL 042-778-9760FAX 042-778-9761 e-mailnyushi@kitasato-u.ac.jp URL http://www.kitasato-u.ac.jp/lisci/index.html

More information

紀要 No,2

紀要 No,2 2003 79 84 Memoirs Kyushu U. Sch. Health Sci., 2003 vol.2 79 84 79 Miyako Oike The purpose of this study was to examine case studies of 3 cancer patients from a viewpoint of narrative and emplotment, and

More information

untitled

untitled ... 4...5...6...7...10...11... 12...12...12...13...14...15...15...16...16...17...17...18...18...19...19...19 Hill...20...20...21...21...22...23...24...25... 34...34...35...38-2 - ...41...49...51...51...51...52...53...56...56...57...60...60-3

More information

Novel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,

More information

untitled

untitled CoQ10 CoQ10 CoQ10 CoQ10 CoQ10 (A CoQ10 CoQ10 B CoQ10 CoQ10 C CoQ10 CoQ10 CoQ10 QOL CoQ10 QOL CoQ10 CoQ10 CoQ10 CoQ10 14 還元型 CoQ10 の摂取はインフルエンザウイルス感染に対する予防効果を示す CoQ1050CoQ10 CoQ1080CoQ10 Åberg et al., Arch

More information

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal transduction Needleman, R., Lanyi, J. K. : Science, 269,73-75 (1995) 3) Bogomolni, R. A., Stoeckenius,

More information

untitled

untitled ORYZA CERAMIDE -PTPCDP8TP20CD -WSPWSP8 -LL0.8 -PCPC8PC20 -WSPCWSPC8 -LCLC0.8 Ver.13.0HS ORYZA CERAMIDE Ver.13.0HS 1. 2. 20 NMR 4 ( 1) 1 Ver.13.0HS HO CH 2 OH O O OH OH OH C CH CH H 2 NH C O R C H C H (CH

More information

Key Words: probabilisic scenario earthquake, active fault data, Great Hanshin earthquake, low frequency-high impact earthquake motion, seismic hazard map 3) Cornell, C. A.: Engineering Seismic

More information

437“ƒ

437“ƒ et al., et al., et al., et al., et al., et al., 2 et al., et al., et al., Lancet Pharmacol Res. et al. Jpn J Cancer Res. et al. Jpn J Cancer Res. et al. Tohoku J Exp Med. et al. Jpn Circ J. et al. Cancer

More information

Validation of a Food Frequency Questionnaire Based on Food Groups for Estimating Individual Nutrient Intake Keiko Takahashi *', Yukio Yoshimura *', Ta

Validation of a Food Frequency Questionnaire Based on Food Groups for Estimating Individual Nutrient Intake Keiko Takahashi *', Yukio Yoshimura *', Ta Validation of a Food Frequency Questionnaire Based on Food Groups for Estimating Individual Nutrient Intake Keiko Takahashi *', Yukio Yoshimura *', Tae Kaimoto *', Daisuke Kunii *', Tatsushi Komatsu *2

More information

Correlation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)

More information

1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,

More information

Juntendo Medical Journal

Juntendo Medical Journal The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical

More information

立命館

立命館 SPORT AND HEALTH SCIENCE Research Study Report 2011 01 02 03 Sport and Health Science 04 PICK UP VOICE 05 Sport and Health Science 06 PICK UP VOICE 07 Sport and Health Science PICK UP VOICE 08 09 Sport

More information

11_渡辺_紀要_2007

11_渡辺_紀要_2007 56 1 19 Bull. Nara Univ. Educ., Vol. 56, No.1 (Cult. & Soc.), 2007 115 19 Why is Kidney Dysfunction Caused by Cadmium (Cadmium Nephropathy) not Officially Recognized as a Pollution-related Disease by the

More information

2004 10 2004 1984 2 1986 4 20 60 1 3 1 1 1 13,300 2 2 2 3 1 2004 2009 2 1 1 2 1 1985 97JR JT NTT 2002 96 97 4 JR JT 97 3 JR 19 29 JT 2.4 2.5 JR JT NTT JR JT NTT 2 97 4 JR 20.09 JT 19.92 NTT 17.35 17.35

More information

untitled

untitled Quantitative Risk Assessment on the Public Health Impact of Pathogenic Vibrio parahaemolyticus in Raw Oyster 1 15 5 23 48 2 21 1 16 1 16 1 11 3 1 3 4 23 1 2 16 12 16 5 6 Hazard IdentificationExposure

More information

繁殖性に及ぼす影響

繁殖性に及ぼす影響 5. 2 1. (DEP) 1) DEP 2) 3) 4) DEP 0 600 3000 15000 ppm(0 43 210 1083 mg/kg/day 0 54 261 1336 mg/kg/day ) 24 Crj:CD(SD) IGS 2 DEP 15000 ppm F0 0-21 F1 F0 F1 DEP F1 F1 15000 ppm 15000 ppm F0 F1 F0 F0 P-450

More information

15K00827 研究成果報告書

15K00827 研究成果報告書 (TG) TG sterol regulatory element- binding protein (SREBP)-1c (Diabetes 53:560-569, 2004) SREBP-1c (1) SREBP-1c SREBP-1c liver X receptor (LXR)LXR O-Glc NAc (O-linked -N-acetyl glucosamine) (J Biol Chem

More information

54-4.ren

54-4.ren 200454 4 604-619 1,3) 1,3) 1,3) 1) 1) 1) 2) 1) 2) 3) 2004.8.1 1) 2) 1) 3) 1 50 4) 2 BC 581 3 4) 4 54 4 2004.8.1 1 1 2 3 3 7 3 1 4 5 5 7 2 3 1 54 4 10 15 4 4) 5 1 6 ) 7) 7) 2004.8.1 8) 8) 8) 8 ) 2 9) c

More information

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c

Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic clinic, Department of Ophthalmology, (Director: Prof

More information

AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urol

AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urol AUTONOMIC FUNCTIONAL STATE IN RENAL TUBERCULOSIS REPORT III. SERUM CHOLINESTERASE ACTIVITY IN RENAL TUBERCULOSIS Sanai Yamamura The Department of Urology, Kumamoto University College of Medicine (Director:

More information

Vol.42 No.1/◇0 目次[三]3.2

Vol.42 No.1/◇0 目次[三]3.2 Department of Applied Biology and Chemistry, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1 1 1, Sakuragaoka, Setagaya-ku, Tokyo 156 8502 Hitachi Health Management Center, 4 3 16, Osecho,

More information

2007 Vol.56 No.6 総説 丸山浩樹

2007 Vol.56 No.6 総説 丸山浩樹 Reprinted from RADIOISOTOPES, Vol.56,.6 June 2007 Japan Radioisotope Association http : //www.jrias.or.jp/ α β α β ε m z α µ µ α m z m z µ µ Curr. Opin. Biotechnol J. Proteome Res Rapid Commun. Mass

More information

Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi

Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi Clinical Study of Effect of Intrathecal Use of Alpha-tocopherol on Chronic Vasospasm Hirotoshi Sano, Motoi Shoda, Youko Kato, Kazuhiro Katada, Youichi Shinomiya and Tetsuo Kanno Department of Neurosurgery,

More information

13 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /., No.3,.*+.*/ (,**1) 401 * * Changes in the Color and Pigmentation of Fermented Benikoji-rice Drink Gok

13 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /., No.3,.*+.*/ (,**1) 401 * * Changes in the Color and Pigmentation of Fermented Benikoji-rice Drink Gok 13 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /., No.3,.*+.*/ (,**1) 401 * * Changes in the Color and Pigmentation of Fermented Benikoji-rice Drink Goki Maeda, Kenichi Higa and Junsei Taira* Okinawa Industrial

More information

後ろ.indd

後ろ.indd 2010 p.1-42 2010 7 The relation between food intake of pregnant women and fetal growth -case sutudy- Vol.11 No.3 p.481-4862010 11 The 10th Hamamatsu-kyungpook Joint Medical Symposium, p.54, School of Medicine,Kyugpook

More information

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書(案)

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書(案) VOL.51 NO.6 JUNE 2003 JUNE 2003 9) Niederman MS et al: Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy and prevention.

More information

52-2.indb

52-2.indb Jpn. J. Health Phys., 52 (2) 55 60 (2017) DOI: 10.5453/jhps.52.55 * 1 * 2 * 2 * 3 * 3 2016 10 28 2017 3 8 Enhancement of Knowledge on Radiation Risk Yukihiko KASAI,* 1 Hiromi KUDO,* 2 Masahiro HOSODA,*

More information