研究用 R&D R&D SYSTEMS 社 Luminexカタログ SYSTEMS Luminex Assay

Transcription

1 研究用 R&D R&D SYSTEMS 社 Luminexカタログ SYSTEMS Luminex Assay

2 R&D Systems Luminex アッセイの原理 測定対象 ( アナライト ) 捕捉抗体 ビオチン標識検出抗体 PE Luminex ビーズ PE ストレプトアビジン PE 測定対象 ( アナライト ) 操作方法概略 試料の入ったプレートに, 測定対象 ( アナライト ) に対する抗体でコートされたビーズを加える ウェルを洗浄した後, ビオチン標識抗体を加える ウェルを洗浄した後,PE 標識ストレプトアビジンを加える ひとつのレーザーでビーズの蛍光強度を測定した後に, 別のレーザーで PE の蛍光強度を測定する これにより, 複数の因子を同時に測定する ビーズの種類と検出方法 ポリスチレンビーズまたは超磁性ビーズ 磁性ビーズ PE Light LED (621 nm) LED (511 nm) ポリスチレンビーズまたは磁性ビーズは, デュアルレーザー式検出システムでシグナルを検出します 一光線により, ビーズの種類が識別されることで, 測定対象が同定されます さらに別の光線により PE 由来シグナルのシグナル強度を測定します 磁性ビーズを用いる系では, 測定対象を捕捉したビーズが, ウェルの底面にモノレイヤーとして固定され, 波長の異なる LED を照射することによって, 測定対象の種類を同定し, シグナル強度を測定します Luminex 検出システム R&D Systems 社の Luminex Assay は, すべての Luminex 検出システムに適合します Luminex 100/200 (Bio-Plex 200) Optics... Lasers/APDs/PMTs Hardware... Flow Cytometry based Bead Compatibility... Magnetic/ Multiplex Capacity (80 for MagPlex) Dynamic Range logs MAGPIX (Bio-Plex MAGPIX) Optics... LED/CCD Camera Hardware... Fluorescent Imager Bead Compatibility... Magnetic Multiplex Capacity Dynamic Range logs FLEXMAP 3D(Bio-Plex 3D) Optics... Lasers/APDs/PMTs Hardware... Flow Cytometry based Bead Compatibility... Magnetic/ Multiplex Capacity Dynamic Range logs 2

3 R&D Systems の Luminex アッセイフォーマット R&D Systems 社の Luminex アッセイは,Luminex Screening Assay と Luminex Performance Assay の 2 つのフォーマットでご提供しています 特 長 Screening Performance 同時に, 最大 100 種類のアナライト Quantikineキットと同等の優れたを検出することができます! 検出感度を発揮します! 測定可能な測定対象の動物種 Species Available 測定に必要な試料の容量 Sample Volume Required 同時測定可能な測定対象数 Multiplex Analyte Capacity ビーズの種類 Bead Type バリデーション済みの試料 Validated Sample Types 検出に必要な時間 Run Time 製品の仕様 Kit Preparation アッセイのバリデーション Assay Validation * 製品ごとに異なります ** 測定対象ごとに異なります Human Mouse Rat µl Sample User-Selected User-Selected from Panel Magnetic 50 User-Selected User-Selected from Panel Magnetic Serum Plasma Supernates See Datasheet* Milk See Datasheet* Saliva See Datasheet* Urine See Datasheet* Hours Premixed End-user Mixed Mean Sensitivity < the low standard** 3/4 the low standard Intra-assay Precision < 20% < 15% Inter-assay Precision < 25% < 17% Recovery (Individual Samples) % Assay Linearity Dose-Dependent 1:2 1:8 Linearity (Individual Samples) Premixed タイプの商品コード 下記商品コードのうしろに ハイフン数字 XX が入ります 数字が測定対象の数を表します Decrease in Values Dose-Dependent Decrease in Values % ( 例 : # LXSAH-08 の場合は, ポリスチレンビーズで検出する Screening Assay,8 plex(8 種類の測定対象を選択できることを示します ) ビーズの種類動物種 Screening Performance ポリスチレンビーズ 超磁性ビーズ ヒト # LXSAH # FCST マウス # LXSAMS ラット # LXSAR ヒト # LXSAHM # FCSTM マウス # LXSAMSM ラット # LXSARM お客様ご自身でビーズと抗体を調製していただく User Mixed タイプもあります 詳細は受託 特注品担当 ( 3

4 優れた検出感度を誇る R&D Systems の Luminex アッセイ R&D Systems 社は, 正確で高感度な定量を可能にする ELISA キット Quantikine シリーズ をはじめ, 抗体を用いたイムノアッセイ製品を製造するメーカーです 1990 年にサイトカイン測定用 ELISA キットを発売開始してから現在に至るまで, 世界中の数多くの研究者様に同社キットが使用されています R&D Systems 社の高い技術力により開発された Luminex アッセイでは, 他社製品よりも卓越した高感度なアナライト検出が可能です HAMA( ヒト抗マウス抗体 ) や RF( リウマチ因子 ) が高濃度に含まれる試料においても, アナライト ( 分析物質 ) を正確に検出することができます 検出抗体 測定対象ではない因子 ( オフターゲット因子 ) 擬陽性の要因となる血清中の干渉物質の影響 捕捉抗体 測定に干渉する因子 Normal Analyte R&D Systems Luminex R&D Systems Luminex Performance Assay Screening Assay Competitor 1 Competitor 2 Competitor 3 TNF- IFN- GM-CSF IL-10 + IL-2 IL-4 IL-5 HAMA-high Analyte R&D Systems Luminex R&D Systems Luminex Performance Assay Screening Assay Competitor 1 Competitor 2 Competitor 3 TNF- IFN- ++ GM-CSF +++ IL IL-2 ++ IL-4 IL-5 RF-high Analyte R&D Systems Luminex R&D Systems Luminex Performance Assay Screening Assay Competitor 1 Competitor 2 Competitor 3 TNF IFN- ++ GM-CSF +++ IL-10 + IL-2 ++ IL IL-5 + 上表 :R&D Systems 社の Luminex panel を用いて,7 種類のアナライトを同時測定した R&D Systems 社のアッセイでは, 他社製品によるアッセイで見られるような擬陽性が検出されない Normal : 正常ヒト血清試料 HAMA-high:HAMAが高濃度 ( ng/ml) に存在する血清試料 RF-high :RFが高濃度(30 42 IU/ml) に存在する血清試料! ご購入時のご注意 本カタログに掲載の製品は, 遺伝子組換え生物等の使用等の規制による生物の多様性の確保に関する法律 ( 通称 : カルタヘナ法 ) 使用規制対象となる可能性があります ご使用に際しては規制に則し, 適切にお取り扱い下さい 詳細は当社テクニカルサポート ( 試薬担当 : 4

5 Screening Assay Human Screening Analytes New Analyte! Analyte available exclusively from R&D Systems Starting Sample Dilution Bead Region Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernatents Serum Heparin Plasma Adiponectin/Acrp , ,013 1:2 1:200 1: Aggrecan ,546 1:2 1:2 1: Fetoprotein 205 1, ,000 1:2 1:2 1:2 41 Amphiregulin ,400 1:2 1:2 1: Angiopoietin ,175 1:2 1:2 1: Angiopoietin-like ,000 1:2 1:2 1:2 42 Angiopoietin-like , ,000 1:2 1:2 1:2 43 APP 349 6,296 1,530,000 1:2 1:2 1: BAFF/BLyS/TNFSF13B ,900 1:2 1:2 1: BCMA ,530 1:2 1:2 1: BMP ,832 1:2 1:2 1: BMP ,462 1:2 1:2 1: BMP ,108 1:2 1:2 1: CA units/ml units/ml 1:2 1:50 1:50 45 CA125/MUC ,800 1:2 1:2 1: Calbindin D ,150 1:2 1:2 1: Cardiac Myoglobin ,700 1:2 1:50 1: Cardiac Troponin I/cTNI ,000 1:2 1:2 1: CCL2/MCP ,914 1:2 1:2 1: CCL3/MIP ,429 1:2 1:2 1: CCL4/MIP ,140 1:2 1:2 1: CCL5/RANTES ,419 1:2 1:50 1: CCL7/MCP ,000 1:2 1:2 1: CCL8/MCP ,700 1:2 1:2 1: CCL13/MCP ,500 1:2 1:2 1: CCL17/TARC ,000 1:2 1:2 1: CCL18/PARC ,300 1:2 1:50 1: CCL20/MIP ,375 1:2 1:2 1: CCL22/MDC ,000 1:2 1:2 1: CCL26/Eotaxin ,000 1:2 1:2 1: CCL27/CTACK ,200 1:2 1:2 1:2 47 CD ,200 1:2 1:200 1: CD ,200 1:2 1:2 1: CD :2 1:2 1: CD ,900 1:2 1:2 1: CD , ,000 1:2 1:2 1: Chemerin :2 1:2 1:2 46 Chitinase 3-like ,783 1:2 1:2 1: Coagulation Factor XIV ,400 1:2 1:50 1: Complement Factor D/ Adipsin Magnetic ,179 1:2 1:50 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. 5

6 Screening Assay Human Screening Analytes Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernatents Starting Sample Dilution New Analyte! Analyte available exclusively from R&D Systems Serum Heparin Plasma Bead Region Cripto ,285 1:2 1:2 1: C-Reactive Protein ,174 1:2 1:200 1: CXCL1/GRO ,150 1:2 1:2 1: CXCL4/PF ,000 1:2 1:200 1: CXCL5/ENA ,433 1:2 1:2 1: CXCL8/IL ,863 1:2 1:2 1: CXCL9/MIG ,000 1:2 1:2 1: CXCL10/IP ,181 1:2 1:2 1: CXCL11/I-TAC ,340 1:2 1:2 1: CXCL12/SFD ,200 1:2 1:2 1:2 60 CXCL13/BLC/BCA ,375 1:2 1:2 1: CXCL ,300 1:2 1:2 1: DcR ,000 1:2 1:2 1: DR3/TNFRSF ,000 1:2 1:2 1: Dkk ,250 1:2 1:2 1: EGF ,323 1:2 1:2 1: Endoglin/CD ,000 1:2 1:2 1:2 49 Endothelin ,300 1:2 1:2 1:2 50 ENPP-2/Autotaxin , ,000 1:2 1:2 1: E-Selectin ,646 1:2 1:2 1: FABP ,000 1:2 1:2 1:2 51 EphA ,900 1:2 1:2 1: Epo ,600 1:2 1:2 1: Fas ,500 1:2 1:2 1: Fas Ligand/TNFSF ,900 1:2 1:2 1: FGF basic ,340 1:2 1:2 1: FGF ,092 1:2 1:2 1: FLRG ,500 1:2 1:2 1: Flt-3 Ligand ,000 1:2 1:2 1:2 52 Follistatin 159 1, ,000 1:2 1:2 1: Galectin ,625 1:2 1:50 1: G-CSF ,114 1:2 1:2 1: GDF ,247 1:2 1:2 1: GDNF ,500 1:2 1:2 1:2 53 GM-CSF ,394 1:2 1:2 1: gp ,500 1:2 1:2 1:2 54 Growth Hormone ,600 1:2 1:2 1: HB-EGF ,618 1:2 1:2 1: HGF ,166 1:2 1:2 1: ICAM-1/CD , ,629 1:2 1:2 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. Magnetic 6

7 Screening Assay Human Screening Analytes Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernatents Starting Sample Dilution Serum New Analyte! Analyte available exclusively from R&D Systems Heparin Plasma Bead Region IFN ,739 1:2 1:2 1: IFN- R :2 1:2 1: IGFBP ,600 1:2 1:2 1: IGFBP , ,000 1:2 1:2 1: IL ,319 1:2 1:2 1: IL ,734 1:2 1:2 1: IL-1ra/IL-1F ,857 1:2 1:2 1: IL-1 RI ,100 1:2 1:2 1: IL-1 RII ,600 1:2 1:2 1: IL ,012 1:2 1:2 1: IL-2 R ,550 1:2 1:2 1: IL ,500 1:2 1:2 1:2 55 IL ,106 1:2 1:2 1: IL ,357 1:2 1:2 1: IL ,094 1:2 1:2 1: IL-6 R ,300 1:2 1:2 1: IL , ,000 1:2 1:2 1: IL ,290 1:2 1:2 1: IL-12 p ,199 1:2 1:2 1: IL ,000 1:2 1:2 1: IL-17A ,791 1:2 1:2 1: IL-17F ,500 1:2 1:2 1: IL-18 BPa ,990 1:2 1:2 1: IL ,608 1:2 1:2 1: IL ,250 1:2 1:2 1: IL , ,338 1:2 1:2 1: IL ,079 1:2 1:2 1: IL-28A/IFN ,130 1:2 1:2 1: IL ,900 1:2 1:2 1: IL ,755 1:2 1:2 1: IL ,700 1:2 1:2 1: Insulin ,800 1:2 1:2 1:2 44 Kallikrein 3/PSA ,000 1:2 1:2 1:2 56 Kallikrein ,000 1:2 1:2 1:2 57 Leptin ,471 1:2 1:2 1: L-Selectin/CD62L 106 1, ,000 1:2 1:2 1:2 58 M-CSF ,000 1:2 1:2 1: MFG-E ,000 1:2 1:2 1: MICA ,500 1:2 1:2 1: MICB ,000 1:2 1:2 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. Magnetic 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 7

8 Screening Assay Human Screening Analytes Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernatents Starting Sample Dilution New Analyte! Analyte available exclusively from R&D Systems Serum Heparin Plasma Bead Region MIF , ,000 1:2 1:2 1: MMP ,104 1:2 1:2 1: MMP ,368 1:2 1:50 1: MMP ,113 1:2 1:2 1: MMP ,263 1:2 1:2 1: MMP ,706 1:2 1:2 1: MMP ,804 1:2 1:50 1: MMP ,699 1:2 1:2 1: MMP ,180 1:2 1:2 1: MPO ,200 1:2 1:50 1: Nephrin ,000 1:2 1:2 1:2 48 NRG1-1/HRG ,850 1:2 1:2 1: Oncostatin M (OSM) ,000 1:2 1:2 1: PDGF-BB ,600 1:2 1:50 1:50 59 Pentraxin 3/TSG ,000 1:2 1:2 1: Periostin/OSF , ,000 1:2 1:2 1: Progranulin 195 1, ,000 1:2 1:2 1: Proprotein Convertase 9/PCSK9 Magnetic 246 1, ,175 1:2 1:2 1: P-Selectin ,562 1:2 1:2 1: RAGE ,250 1:2 1:2 1: Renin ,000 1:2 1:2 1: Resistin ,870 1:2 1:2 1: ROBO ,900 1:2 1:2 1: SCF ,000 1:2 1:2 1: Serpin E1/PAI ,500 1:2 1:200 1: Serpin C1/ Antithrombin- III 207 2, ,000 1:2 1:200 1: SHBG ,578 2,570,560 1:2 1:50 1: SOST ,775 1:2 1:2 1: SPARC , ,600 1:2 1:50 1: SP-D ,000 1:2 1:2 1: ST2/IL-1 R ,080 1:2 1:2 1: TACI ,650 1:2 1:2 1: Tenascin C ,000 1:2 1:2 1: TFPI ,000 1:2 1:2 1: TfR ,000 1:2 1:200 1: Thrombospondin ,000 1:2 1:2 1: Tie ,000 1:2 1:2 1: Tie ,600 1:2 1:2 1: TNF ,020 1:2 1:2 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. 8

9 Screening Assay Human Screening Analytes New Analyte! Analyte available exclusively from R&D Systems Starting Sample Dilution Bead Region Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernatents Serum Heparin Plasma TNF RI ,600 1:2 1:2 1: TNF RII ,380 1:2 1:2 1: Tpo ,005 1:2 1:2 1: TRAIL R2/TNFRSF10B ,000 1:2 1:2 1: TRAIL R ,900 1:2 1:2 1: TRANCE/RANK L/ TNFSF11 Magnetic ,450 1:2 1:2 1: ULBP ,500 1:2 1:2 1: ULBP-2/5/ ,000 1:2 1:2 1: ULBP ,300 1:2 1:2 1: ULBP-4/RAET1E ,000 1:2 1:2 1: upar ,300 1:2 1:2 1: Uteroglobin ,000 1:2 1:50 1: VAP ,700 1:2 1:50 1: VCAM ,016 3,162,958 1:2 1:2 1: VEGF ,853 1:2 1:2 1: VEGF-C ,700 1:2 1:2 1: VEGF R ,100 1:2 1:2 1: vwf-a ,000 1:2 1:2 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 9

10 Screening Assay Human Screening Analytes( ポリスチレンビーズ ) 価格表 品名商品コード価格 ( ) Human Luminex Screening Assay (1 PLEX) LXSAH-01 73,000 Human Luminex Screening Assay (2 PLEX) LXSAH-02 84,000 Human Luminex Screening Assay (3 PLEX) LXSAH ,000 Human Luminex Screening Assay (4 PLEX) LXSAH ,000 Human Luminex Screening Assay (5 PLEX) LXSAH ,000 Human Luminex Screening Assay (6 PLEX) LXSAH ,000 Human Luminex Screening Assay (7 PLEX) LXSAH ,000 Human Luminex Screening Assay (8 PLEX) LXSAH ,000 Human Luminex Screening Assay (9 PLEX) LXSAH ,000 Human Luminex Screening Assay (10 PLEX) LXSAH ,000 Human Luminex Screening Assay (11 PLEX) LXSAH ,000 Human Luminex Screening Assay (12 PLEX) LXSAH ,000 Human Luminex Screening Assay (13 PLEX) LXSAH ,000 Human Luminex Screening Assay (14 PLEX) LXSAH ,000 Human Luminex Screening Assay (15 PLEX) LXSAH ,000 Human Luminex Screening Assay (16 PLEX) LXSAH ,000 Human Luminex Screening Assay (17 PLEX) LXSAH ,000 Human Luminex Screening Assay (18 PLEX) LXSAH ,000 Human Luminex Screening Assay (19 PLEX) LXSAH ,000 Human Luminex Screening Assay (20 PLEX) LXSAH ,000 Human Luminex Screening Assay (21 PLEX) LXSAH ,000 Human Luminex Screening Assay (22 PLEX) LXSAH ,000 Human Luminex Screening Assay (23 PLEX) LXSAH ,000 Human Luminex Screening Assay (24 PLEX) LXSAH ,000 Human Luminex Screening Assay (25 PLEX) LXSAH ,000 Human Luminex Screening Assay (26 PLEX) LXSAH ,000 Human Luminex Screening Assay (27 PLEX) LXSAH ,000 Human Luminex Screening Assay (28 PLEX) LXSAH ,000 Human Luminex Screening Assay (29 PLEX) LXSAH ,000 Human Luminex Screening Assay (30 PLEX) LXSAH ,000 Human Luminex Screening Assay (31 PLEX) LXSAH ,000 Human Luminex Screening Assay (32 PLEX) LXSAH ,000 Human Luminex Screening Assay (33 PLEX) LXSAH ,000 Human Luminex Screening Assay (34 PLEX) LXSAH ,000 Human Luminex Screening Assay (35 PLEX) LXSAH ,000 Human Luminex Screening Assay (36 PLEX) LXSAH ,000 Human Luminex Screening Assay (37 PLEX) LXSAH ,000 Human Luminex Screening Assay (38 PLEX) LXSAH-38 1,010,000 Human Luminex Screening Assay (39 PLEX) LXSAH-39 1,035,000 Human Luminex Screening Assay (40 PLEX) LXSAH-40 1,061,000 Human Luminex Screening Assay (41 PLEX) LXSAH-41 1,086,000 Human Luminex Screening Assay (42 PLEX) LXSAH-42 1,113,000 Human Luminex Screening Assay (43 PLEX) LXSAH-43 1,138,000 Human Luminex Screening Assay (44 PLEX) LXSAH-44 1,164,000 Human Luminex Screening Assay (45 PLEX) LXSAH-45 1,189,000 Human Luminex Screening Assay (46 PLEX) LXSAH-46 1,215,000 Human Luminex Screening Assay (47 PLEX) LXSAH-47 1,241,000 Human Luminex Screening Assay (48 PLEX) LXSAH-48 1,267,000 Human Luminex Screening Assay (49 PLEX) LXSAH-49 1,292,000 Human Luminex Screening Assay (50 PLEX) LXSAH-50 1,318,000 品名 商品コード 価格 ( ) Human Luminex Screening Assay (51 PLEX) LXSAH-51 Human Luminex Screening Assay (52 PLEX) LXSAH-52 Human Luminex Screening Assay (53 PLEX) LXSAH-53 Human Luminex Screening Assay (54 PLEX) LXSAH-54 Human Luminex Screening Assay (55 PLEX) LXSAH-55 Human Luminex Screening Assay (56 PLEX) LXSAH-56 Human Luminex Screening Assay (57 PLEX) LXSAH-57 Human Luminex Screening Assay (58 PLEX) LXSAH-58 Human Luminex Screening Assay (59 PLEX) LXSAH-59 Human Luminex Screening Assay (60 PLEX) LXSAH-60 Human Luminex Screening Assay (61 PLEX) LXSAH-61 Human Luminex Screening Assay (62 PLEX) LXSAH-62 Human Luminex Screening Assay (63 PLEX) LXSAH-63 Human Luminex Screening Assay (64 PLEX) LXSAH-64 Human Luminex Screening Assay (65 PLEX) LXSAH-65 Human Luminex Screening Assay (66 PLEX) LXSAH-66 Human Luminex Screening Assay (67 PLEX) LXSAH-67 Human Luminex Screening Assay (68 PLEX) LXSAH-68 Human Luminex Screening Assay (69 PLEX) LXSAH-69 Human Luminex Screening Assay (70 PLEX) LXSAH-70 Human Luminex Screening Assay (71 PLEX) LXSAH-71 Human Luminex Screening Assay (72 PLEX) LXSAH-72 Human Luminex Screening Assay (73 PLEX) LXSAH-73 Human Luminex Screening Assay (74 PLEX) LXSAH-74 Human Luminex Screening Assay (75 PLEX) LXSAH-75 Human Luminex Screening Assay (76 PLEX) LXSAH-76 お問い合わせ下さい Human Luminex Screening Assay (77 PLEX) LXSAH-77 Human Luminex Screening Assay (78 PLEX) LXSAH-78 Human Luminex Screening Assay (79 PLEX) LXSAH-79 Human Luminex Screening Assay (80 PLEX) LXSAH-80 Human Luminex Screening Assay (81 PLEX) LXSAH-81 Human Luminex Screening Assay (82 PLEX) LXSAH-82 Human Luminex Screening Assay (83 PLEX) LXSAH-83 Human Luminex Screening Assay (84 PLEX) LXSAH-84 Human Luminex Screening Assay (85 PLEX) LXSAH-85 Human Luminex Screening Assay (86 PLEX) LXSAH-86 Human Luminex Screening Assay (87 PLEX) LXSAH-87 Human Luminex Screening Assay (88 PLEX) LXSAH-88 Human Luminex Screening Assay (89 PLEX) LXSAH-89 Human Luminex Screening Assay (90 PLEX) LXSAH-90 Human Luminex Screening Assay (91 PLEX) LXSAH-91 Human Luminex Screening Assay (92 PLEX) LXSAH-92 Human Luminex Screening Assay (93 PLEX) LXSAH-93 Human Luminex Screening Assay (94 PLEX) LXSAH-94 Human Luminex Screening Assay (95 PLEX) LXSAH-95 Human Luminex Screening Assay (96 PLEX) LXSAH-96 Human Luminex Screening Assay (97 PLEX) LXSAH-97 Human Luminex Screening Assay (98 PLEX) LXSAH-98 Human Luminex Screening Assay (99 PLEX) LXSAH-99 Human Luminex Screening Assay (100 PLEX) LXSAH

11 Screening Assay Human Screening Analytes( 磁性ビーズ ) 価格表 品名商品コード価格 ( ) Human Magnetic Luminex Screening Assay (1 PLEX) LXSAHM-01 73,000 Human Magnetic Luminex Screening Assay (2 PLEX) LXSAHM-02 84,000 Human Magnetic Luminex Screening Assay (3 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (4 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (5 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (6 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (7 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (8 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (9 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (10 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (11 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (12 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (13 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (14 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (15 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (16 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (17 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (18 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (19 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (20 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (21 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (22 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (23 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (24 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (25 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (26 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (27 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (28 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (29 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (30 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (31 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (32 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (33 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (34 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (35 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (36 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (37 PLEX) LXSAHM ,000 Human Magnetic Luminex Screening Assay (38 PLEX) LXSAHM-38 1,010,000 Human Magnetic Luminex Screening Assay (39 PLEX) LXSAHM-39 1,035,000 Human Magnetic Luminex Screening Assay (40 PLEX) LXSAHM-40 1,061,000 Human Magnetic Luminex Screening Assay (41 PLEX) LXSAHM-41 1,086,000 Human Magnetic Luminex Screening Assay (42 PLEX) LXSAHM-42 1,113,000 Human Magnetic Luminex Screening Assay (43 PLEX) LXSAHM-43 1,138,000 Human Magnetic Luminex Screening Assay (44 PLEX) LXSAHM-44 1,164,000 Human Magnetic Luminex Screening Assay (45 PLEX) LXSAHM-45 1,189,000 Human Magnetic Luminex Screening Assay (46 PLEX) LXSAHM-46 1,215,000 Human Magnetic Luminex Screening Assay (47 PLEX) LXSAHM-47 1,241,000 Human Magnetic Luminex Screening Assay (48 PLEX) LXSAHM-48 1,267,000 Human Magnetic Luminex Screening Assay (49 PLEX) LXSAHM-49 1,292,000 Human Magnetic Luminex Screening Assay (50 PLEX) LXSAHM-50 1,318,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 11

12 Screening Assay Mouse Screening Analytes New Analyte! Analyte available exclusively from R&D Systems Starting Sample Dilution Bead Region Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernates Serum/ Plasma BAFF/BLyS/TNFSF13B ,818 1:2 1: C1q R1/CD ,350 1:2 1: CCL2/JE/MCP ,802 1:2 1: CCL3/MIP ,692 1:2 1: CCL4/MIP ,525 1:2 1: CCL5/RANTES ,138 1:2 1: CCL20/MIP ,660 1:2 1: CRP ,850 1:2 1:2 63 CXCL1/KC ,463 1:2 1: CXCL2/MIP ,403 1:2 1: CXCL10/IP-10/CRG ,908 1:2 1: CXCL12/SDF ,073 1:2 1: Epo ,783 1:2 1: FGF ,190 1:2 1: FGF basic ,340 1:2 1: G-CSF ,330 1:2 1: GM-CSF ,595 1:2 1: IFN ,294 1:2 1: IGF-I ,783 1:50 1: IL ,983 1:2 1: IL ,778 1:2 1: IL ,404 1:2 1: IL ,223 1:2 1: IL ,669 1:2 1: IL ,983 1:2 1: IL ,615 1:2 1: IL-12 p ,090 1:2 1: IL ,025 1:2 1: IL-17A :2 1: IL-23 p :2 1: IL :2 1: Leptin ,180 1:2 1: Lipocalin-2/NGAL ,270 1:50 1: LIX ,975 1:2 1: M-CSF ,432 1:2 1: MMP ,858 1:50 1: Osteopontin ,728 1:50 1: Proprotein Convertase 9/ PCSK9 Magnetic ,138 1:2 1: Resistin ,076 1:50 1: TNF :2 1: VEGF ,753 1:2 1: *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. 12

13 Screening Assay Mouse Screening Analytes 価格表 ポリスチレンビーズフォーマット 磁性ビーズフォーマット 品名 商品コード 価格 ( ) 品名 商品コード 価格 ( ) Mouse Luminex Screening Assay (1 PLEX) LXSAMS-01 73,000 Mouse Magnetic Luminex Screening Assay (1 PLEX) LXSAMSM-01 73,000 Mouse Luminex Screening Assay (2 PLEX) LXSAMS-02 84,000 Mouse Magnetic Luminex Screening Assay (2 PLEX) LXSAMSM-02 84,000 Mouse Luminex Screening Assay (3 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (3 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (4 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (4 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (5 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (5 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (6 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (6 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (7 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (7 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (8 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (8 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (9 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (9 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (10 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (10 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (11 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (11 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (12 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (12 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (13 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (13 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (14 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (14 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (15 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (15 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (16 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (16 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (17 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (17 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (18 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (18 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (19 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (19 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (20 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (20 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (21 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (21 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (22 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (22 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (23 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (23 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (24 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (24 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (25 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (25 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (26 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (26 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (27 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (27 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (28 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (28 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (29 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (29 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (30 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (30 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (31 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (31 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (32 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (32 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (33 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (33 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (34 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (34 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (35 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (35 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (36 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (36 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (37 PLEX) LXSAMS ,000 Mouse Magnetic Luminex Screening Assay (37 PLEX) LXSAMSM ,000 Mouse Luminex Screening Assay (38 PLEX) LXSAMS-38 1,010,000 Mouse Magnetic Luminex Screening Assay (38 PLEX) LXSAMSM-38 1,010,000 Mouse Luminex Screening Assay (39 PLEX) LXSAMS-39 1,035,000 Mouse Magnetic Luminex Screening Assay (39 PLEX) LXSAMSM-39 1,035,000 Mouse Luminex Screening Assay (40 PLEX) LXSAMS-40 1,061,000 Mouse Magnetic Luminex Screening Assay (40 PLEX) LXSAMSM-40 1,061,000 Mouse Luminex Screening Assay (41 PLEX) LXSAMS-41 1,086,000 Mouse Magnetic Luminex Screening Assay (41 PLEX) LXSAMSM-41 1,086,000 Mouse Luminex Screening Assay (42 PLEX) LXSAMS-42 1,113,000 Mouse Magnetic Luminex Screening Assay (42 PLEX) LXSAMSM-42 1,113,000 Mouse Magnetic Luminex Screening Assay (43 PLEX) LXSAMSM-43 1,138,000 Mouse Magnetic Luminex Screening Assay (44 PLEX) LXSAMSM-44 1,164,000 Mouse Magnetic Luminex Screening Assay (45 PLEX) LXSAMSM-45 1,189,000 Mouse Magnetic Luminex Screening Assay (46 PLEX) LXSAMSM-46 1,215,000 Mouse Magnetic Luminex Screening Assay (47 PLEX) LXSAMSM-47 1,241,000 Mouse Magnetic Luminex Screening Assay (48 PLEX) LXSAMSM-48 1,267,000 Mouse Magnetic Luminex Screening Assay (49 PLEX) LXSAMSM-49 1,292,000 Mouse Magnetic Luminex Screening Assay (50 PLEX) LXSAMSM-50 1,318,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 13

14 Screening Assay Rat Screening Analytes New Analyte! Analyte available exclusively from R&D Systems Starting Sample Dilution Bead Region Analyte Sensitivity (Mean Minimum Detectible Dose; pg/ml) Supernates Serum EDTA Plasma Heparin Plasma CXCL2/CINC ,100 None 1:2 1:2 1: CXCL3/CINC-2 / ,400 None 1:2 1:2 1: GM-CSF ,800 None 1:4 1:2 1: ICAM-1/CD ,600 None 1:4 1:4 1: IFN ,400 None 1:2 1:2 1: IL-1 /IL-1F ,000 None 1:4 1:2 1: IL-1 /IL-1F ,000 None 1:2 1:4 1: IL ,800 None 1:4 1:4 1: IL ,500 None 1:4 1:2 1: IL , ,000 None 1:2 1:2 1: IL ,000 None 1:2 1:2 1: IL ,200 None 1:4 1:4 1: IL ,700 None 1:2 1:2 1: L Selectin/CD62L ,400 None 1:4 1:4 1: TIMP ,600 None 1:4 1:4 1: TNF ,200 None 1:2 1:2 1: VEGF ,000 None 1:4 1:2 N/R *A standard curve must be generated each time an assay is run utilizing values from the Certificate of Analysis provided with each Luminex Screening Assay. Magnetic 14

15 Screening Assay Rat Screening Analytes 価格表 ポリスチレンビーズフォーマット 磁性ビーズフォーマット 品名商品コード価格 ( ) 品名商品コード価格 ( ) Rat Luminex Screening Assay (1 PLEX) LXSAR-01 73,000 Rat Magnetic Luminex Screening Assay (1 PLEX) LXSARM-01 73,000 Rat Luminex Screening Assay (2 PLEX) LXSAR-02 84,000 Rat Magnetic Luminex Screening Assay (2 PLEX) LXSARM-02 84,000 Rat Luminex Screening Assay (3 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (3 PLEX) LXSARM ,000 Rat Luminex Screening Assay (4 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (4 PLEX) LXSARM ,000 Rat Luminex Screening Assay (5 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (5 PLEX) LXSARM ,000 Rat Luminex Screening Assay (6 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (6 PLEX) LXSARM ,000 Rat Luminex Screening Assay (7 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (7 PLEX) LXSARM ,000 Rat Luminex Screening Assay (8 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (8 PLEX) LXSARM ,000 Rat Luminex Screening Assay (9 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (9 PLEX) LXSARM ,000 Rat Luminex Screening Assay (10 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (10 PLEX) LXSARM ,000 Rat Luminex Screening Assay (11 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (11 PLEX) LXSARM ,000 Rat Luminex Screening Assay (12 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (12 PLEX) LXSARM ,000 Rat Luminex Screening Assay (13 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (13 PLEX) LXSARM ,000 Rat Luminex Screening Assay (14 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (14 PLEX) LXSARM ,000 Rat Luminex Screening Assay (15 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (15 PLEX) LXSARM ,000 Rat Luminex Screening Assay (16 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (16 PLEX) LXSARM ,000 Rat Luminex Screening Assay (17 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (17 PLEX) LXSARM ,000 Rat Luminex Screening Assay (18 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (18 PLEX) LXSARM ,000 Rat Luminex Screening Assay (19 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (19 PLEX) LXSARM ,000 Rat Luminex Screening Assay (20 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (20 PLEX) LXSARM ,000 Rat Luminex Screening Assay (21 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (21 PLEX) LXSARM ,000 Rat Luminex Screening Assay (22 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (22 PLEX) LXSARM ,000 Rat Luminex Screening Assay (23 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (23 PLEX) LXSARM ,000 Rat Luminex Screening Assay (24 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (24 PLEX) LXSARM ,000 Rat Luminex Screening Assay (25 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (25 PLEX) LXSARM ,000 Rat Luminex Screening Assay (26 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (26 PLEX) LXSARM ,000 Rat Luminex Screening Assay (27 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (27 PLEX) LXSARM ,000 Rat Luminex Screening Assay (28 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (28 PLEX) LXSARM ,000 Rat Luminex Screening Assay (29 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (29 PLEX) LXSARM ,000 Rat Luminex Screening Assay (30 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (30 PLEX) LXSARM ,000 Rat Luminex Screening Assay (31 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (31 PLEX) LXSARM ,000 Rat Luminex Screening Assay (32 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (32 PLEX) LXSARM ,000 Rat Luminex Screening Assay (33 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (33 PLEX) LXSARM ,000 Rat Luminex Screening Assay (34 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (34 PLEX) LXSARM ,000 Rat Luminex Screening Assay (35 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (35 PLEX) LXSARM ,000 Rat Luminex Screening Assay (36 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (36 PLEX) LXSARM ,000 Rat Luminex Screening Assay (37 PLEX) LXSAR ,000 Rat Magnetic Luminex Screening Assay (37 PLEX) LXSARM ,000 Rat Luminex Screening Assay (38 PLEX) LXSAR-38 1,010,000 Rat Magnetic Luminex Screening Assay (38 PLEX) LXSARM-38 1,010,000 Rat Luminex Screening Assay (39 PLEX) LXSAR-39 1,035,000 Rat Magnetic Luminex Screening Assay (39 PLEX) LXSARM-39 1,035,000 Rat Luminex Screening Assay (40 PLEX) LXSAR-40 1,061,000 Rat Magnetic Luminex Screening Assay (40 PLEX) LXSARM-40 1,061,000 Rat Luminex Screening Assay (41 PLEX) LXSAR-41 1,086,000 Rat Magnetic Luminex Screening Assay (41 PLEX) LXSARM-41 1,086,000 Rat Luminex Screening Assay (42 PLEX) LXSAR-42 1,113,000 Rat Magnetic Luminex Screening Assay (42 PLEX) LXSARM-42 1,113,000 Rat Magnetic Luminex Screening Assay (43 PLEX) LXSARM-43 1,138,000 Rat Magnetic Luminex Screening Assay (44 PLEX) LXSARM-44 1,164,000 Rat Magnetic Luminex Screening Assay (45 PLEX) LXSARM-45 1,189,000 Rat Magnetic Luminex Screening Assay (46 PLEX) LXSARM-46 1,215,000 Rat Magnetic Luminex Screening Assay (47 PLEX) LXSARM-47 1,241,000 Rat Magnetic Luminex Screening Assay (48 PLEX) LXSARM-48 1,267,000 Rat Magnetic Luminex Screening Assay (49 PLEX) LXSARM-49 1,292,000 Rat Magnetic Luminex Screening Assay (50 PLEX) LXSARM-50 1,318,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 15

16 Performance Assay Human Angiogenesis Panel * Catalog # Analyte available exclusively from R&D Systems Analyte Magnetic Sensitivity/MDD (pg/ml) Human Angiogenesis Panel Base Kit LAN000 LANM000 Angiogenin LAN265 LANM ,500 Angiopoietin-1 LAN923 LANM ,000 Endostatin LAN1098 LANM ,000 FGF acidic LAN232 LANM ,800 FGF basic LUH233 LANM ,700 PDGF-AA LAN221 LANM ,710 PDGF-BB LAN220 LANM ,100 PlGF LAN264 LANM ,150 Thrombospondin-2 LAN1635 LANM ,400 VEGF LUH293 LANM ,600 VEGF-D LAN622 LANM ,500 Analyte Supernates Validated Samples and Recommended Starting Dilution Serum EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma Urine Human Milk Microparticle Region Human Angiogenesis Panel Base Kit Angiogenin 1:5 1:5 1:50 1:5 1: Angiopoietin-1 1:5 1:5 1:5** 1:5 1: Endostatin 1:5 1:5 1:5 1:5 1: FGF acidic 1:5 1:5 1:5 1:5 1: FGF basic 1:5 1:5 1:5*** 1:5 1: PDGF-AA 1:5 1:5 1:5** 1:5 1: PDGF-BB 1:5 1:5 1:5** 1:5 1: PlGF 1:5 1:5 1:5 1:5 1: Thrombospondin-2 1:5 1:5 1:5 1:5 1: VEGF 1:5 1:5 1:5 1:5 1: VEGF-D 1:5 1:5 1:5 1:5 1: * A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. ** Angiopoietin-1, PDGF-AA, and PDGF-BB are present in platelet granules and are released upon platelet activation. Therefore, to measure circulating levels of these factors, platelet-poor plasma should be collected for measurement. *** Heparin plasma and platelet-poor heparin plasma are not suitable for use in the FGF basic assay. Magnetic 16 品名商品コード価格 ( ) Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (1 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (2 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (3 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (4 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (5 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (6 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (7 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (8 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (9 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (10 PLEX) FCST ,000 Human Angiogenesis Custom Premix Fluorokine MAP Kit, 1 Plate (11 PLEX) FCST ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (1 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (2 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (3 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (4 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (5 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (6 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (7 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (8 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (9 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (10 PLEX) FCSTM ,000 Human Angiogenesis A Premixed Mag Luminex Performance Assay (11 PLEX) FCSTM ,000

17 Performance Assay Human Biomarker Panel A * Analyte Catalog # Human Biomarker Panel A Base Kit Sensitivity/ MDD (pg/ml) Analyte available exclusively from R&D Systems Validated Samples and Recommended Starting Dilution Supernate Serum, EDTA Plasma, Heparin Plasma Microparticle Region LBA000 BAFF/BLyS/TNFSF13B LBA ,290 1:2 1:3 13 CCL20/MIP-3 LBA ,350 1:2 1:3 19 CD14 LBA ,500 1:2 1:50 59 CD27/TNFRSF7 LBA ,600 1:2 1:3 26 CXCL13/BLC/BCA-1 LBA ,060 1:2 1:3 22 gp130 LBA ,500 1:2 1:50 60 IL-2 R LBA ,780 1:2 1:3 32 IL-6 R LBA ,200 1:2 1:50 79 TNF RII/TNFRSF1B LUCA :2 1:50 50 *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名 商品コード 価格 ( ) Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (1 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (2 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (3 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (4 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (5 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (6 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (7 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (8 PLEX) FCST ,000 Human Biomarker Custom Premix Fluorokine MAP Kit A, 1 Plate (9 PLEX) FCST ,000 Human Cardiac Panel A * Analyte Catalog # Human Cardiac Panel A Base Kit Sensitivity/ MDD (pg/ml) Validated Samples and Analyte available exclusively from R&D Systems Recommended Starting Dilution Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma Microparticle Region LUCA000 CD40 Ligand LUB ,300 1:10** 18 GDF-15 LUCA ,650 1:10 2 Pappalysin-1/PAPP-A LUCA ,000 1:10 13 Proprotein Convertase 9/ PCSK9 LUCA ,000 1:10 16 ST2/IL-1R4 LUCA ,400 1:10 30 TNF RII LUCA ,800 1:10 50 * A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. **CD40 Ligand is present in platelet granules and is released upon platelet activation. Therefore, to measure circulating levels of CD40 Ligand, plateletpoor plasma should be collected for measurement. 品名 商品コード 価格 ( ) Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (1 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (2 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (3 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (4 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (5 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit A, 1 Plate (6 PLEX) FCST ,000 17

18 Performance Assay Human Cardiac Panel B * Analyte Catalog # Human Cardiac Panel B Base Kit Sensitivity/MDD (pg/ml) Validated Samples and Recommended Starting Dilution Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma Microparticle Region LUCB000 C-Reactive Protein LUCB ,000 1:100 4 Cystatin C LUCB ,000 1:100 8 Myeloperoxidase LUCB ,700 1:100** 12 P-Selectin LUCB ,600 1: Serpin E1/PAI-1 LUCB ,550 1: TIMP-1 LUCB ,700 1: * A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. ** Myeloperoxidase is present in neutrophil granules and is released upon neutrophil exposure to activated platelets. Therefore, to measure circulating levels of myeloperoxidase, platelet-poor plasma should be collected for measurement. 品名 商品コード 価格 ( ) Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (1 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (2 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (3 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (4 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (5 PLEX) FCST ,000 Human Cardiac Custom Premix Fluorokine MAP Kit B, 1 Plate (6 PLEX) FCST ,000 18

19 Performance Assay Human Cytokine Panel A * Catalog # Validated Samples and Recommended Starting Dilution Microparticle Region Analyte Magnetic Human Cytokine Panel A Base Kit Sensitivity/ MDD (pg/ml) Standard Curve Range* (pg/ ml) Supernates Serum, EDTA Plasma, Heparin Plasma LUH000 LUHM000 CCL2/MCP-1 LUH279 LUHM ,450 None 1: CCL3/MIP-1 LUH270 LUHM ,500 None 1:4** CCL4/MIP-1 LUH271 LUHM ,000 None 1: CCL5/RANTES LUH278 LUHM ,500 None 1: CXCL8/IL-8 LUH208 LUHM ,850 None 1: CXCL5/ENA-78 LUH254 LUHM ,700 None 1: FGF basic LUH233 LUHM ,700 None 1: G-CSF LUH214 LUHM ,850 None 1: GM-CSF LUH215C LUHM ,650 None 1: IFN- LUH285 LUHM ,200 None 1: IL-1 /IL-1F1 LUH200B LUHM ,750 None 1: IL-1ra/IL-1F3 LUH280 LUHM ,750 None 1: IL-1 /IL-1F2 LUH201 LUHM ,050 None 1: IL-2 LUH202 LUHM ,100 None 1: IL-4 LUH204 LUHM ,150 None 1: IL-5 LUH205 LUHM ,400 None 1: IL-6 LUH206 LUHM ,050 None 1: IL-10 LUH217 LUHM ,250 None 1: IL-17 LUH317 LUHM ,250 None 1: TNF- LUH210 LUHM ,950 None 1: Thrombopoietin / Tpo Magnetic LUH288 LUHM ,000 None 1: VEGF LUH293 LUHM ,500 None 1: * A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. ** Heparin plasma is not recommended for use with the CCL3/MIP-1 assay. 品名商品コード価格 ( ) Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (1 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (2 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (3 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (4 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (5 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (6 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (7 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (8 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (9 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (10 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (11 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (12 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (13 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (14 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (15 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (16 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (17 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (18 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (19 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (20 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (21 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit A, 1 Plate (22 PLEX) FCST ,000 19

20 Performance Assay 品名 商品コード 価格 ( ) Human Cytokine A Premixed Magnetic Luminex Performance Assay (1 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (2 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (3 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (4 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (5 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (6 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (7 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (8 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (9 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (10 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (11 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (12 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (13 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (14 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (15 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (16 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (17 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (18 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (19 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (20 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (21 PLEX) FCSTM ,000 Human Cytokine A Premixed Magnetic Luminex Performance Assay (22 PLEX) FCSTM ,000 20

21 Performance Assay Human Cytokine Panel B * Analyte Catalog # Human Cytokine Panel B Base Kit Sensitivity/MDD (pg/ml) Validated Samples and Recommended Starting Dilution Supernates Serum, EDTA Plasma, Heparin Plasma Microparticle Region LUB000 CCL11/Eotaxin LUB ,900** None 1:4 22 CD40 Ligand LUB ,400 None 1:4 18 CXCL10/IP-10 LUB ,800 1:15 1:4*** 39 CXCL11/I-TAC LUB ,800 None 1:4 60 EGF LUB ,700 None 1:4 51 HGF LUB ,600 None 1:4 53 IL-12 p70 LUB ,100 1:2 1:4 7 IL-13 LUB ,600 None 1:4 35 Leptin LUB ,700 None 1:4 31 *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. ** This is the standard curve range for Eotaxin when assaying serum and plasma samples. The standard curve range when assaying cell culture supernate samples is ,900 pg/ml. ***Serum and EDTA Plasma are not recommended for use with the CXCL10/IP-10 assay. 品名 商品コード 価格 ( ) Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (1 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (2 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (3 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (4 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (5 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (6 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (7 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (8 PLEX) FCST ,000 Human Cytokine Custom Premix Fluorokine MAP Kit B, 1 Plate (9 PLEX) FCST ,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 21

22 Performance Assay Human HS Cytokine Panel A * Catalog # Analyte Magnetic Human High Sensitivity Cytokine Panel A Base Kit Sensitivity/ MDD (pg/ml) Standard Curve Range* (pg/ml) Serum, EDTA Plasma, Heparin Plasma Microparticle Region Magnetic LHSC000 LHSCM000 CXCL8/IL-8 LHSC208 LHSCM ,100 1: GM-CSF LHSC215 LHSCM ,600 1: IFN- LHSC285 LHSCM ,490 1: IL-1 LHSC201 LHSCM ,600 1: IL-2 LHSC202 LHSCM ,500 1: IL-4 LHSC204 LHSCM ,000 1: IL-5 LHSC205 LHSCM ,600 1: IL-6 LHSC206 LHSCM ,100 1: IL-10 LHSC217 LHSCM ,100 1: IL-12 p70 LHSC219 LHSCM ,000 1: TNF- LHSC210 LHSCM ,700 1: VEGF LHSC293 LHSCM ,100 1: *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名 商品コード 価格 ( ) Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (1 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (2 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (3 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (4 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (5 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (6 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (7 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (8 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (9 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (10 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (11 PLEX) FCST ,000 Human HS Cytokine Premix Fluorokine MAP Kit, 1 Plate (12 PLEX) FCST ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (1 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (2 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (3 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (4 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (5 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (6 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (7 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (8 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (9 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (10 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (11 PLEX) FCSTM ,000 Human HS Cytokine A Premixed Mag Luminex Performance Assay (12 PLEX) FCSTM ,000 22

23 Performance Assay Human HS Cytokine Panel B * Analyte Catalog # Human High Sensitivity Cytokine Panel B Base Kit Sensitivity/MDD (pg/ml) Range* (pg/ml) Supernates Analyte available exclusively from R&D Systems Serum, EDTA Plasma, Heparin Plasma Magnetic Microparticle Region LBHS000 GM-CSF LHSCM ,550 None 1:2 29 IFN- LHSCM None 1:2 30 IL-1 /IL-1F2 LHSCM ,240 None 1:2 20 IL-2 LHSCM ,850 None 1:2 19 IL-5 LHSCM ,100 None 1:2 22 IL-6 LHSCM ,650 None 1:2 25 IL-7 LBHS ,390 None 1:2 33 IL-10 LHSCM ,400 None 1:2 27 IL-13 LBHS ,600 None 1:2 34 IL-15 LBHS ,420 None 1:2 35 IL-17A LBHS ,370 None 1:2 36 IL-17F LBHS ,750 None 1:2 37 IL-22 LBHS ,700 None 1:2 38 IL-23 LBHS ,000 None 1:2 39 IL-31 LBHS ,100 None 1:2 42 IL-33 LBHS ,000 None 1:2 18 IL-36 LBHS ,160 None 1:2 15 TNF- LHSCM ,920 None 1:2 12 *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名 商品コード 価格 ( ) Human HS Cytokine B Premixed Mag Luminex Performance Assay (1 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (2 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (3 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (4 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (5 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (6 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (7 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (8 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (9 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (10 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (11 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (12 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (13 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (14 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (15 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (16 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (17 PLEX) FCSTM ,000 Human HS Cytokine B Premixed Mag Luminex Performance Assay (18 PLEX) FCSTM ,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 23

24 Performance Assay Human Kidney Biomarkers Panel * Analyte Catalog # Human Kidney Biomarker Panel Base Kit Sensitivity/MDD (pg/ml) Analyte available exclusively from R&D Systems Validated Samples and Recommended Starting Dilution Serum, EDTA Plasma, Heparin Plasma Urine Magnetic Microparticle Region LHK000 Clusterin LHK ,100 1:4,000 1:10 20 Cystatin C LHK ,600 1:4,000 1:10 19 CXCL10/IP-10 LHK ,700 1:10 1:10 25 Fetuin A/AHSG LHK ,498 2,550,000 1:4,000 1:10 21 Lipocalin-2/NGAL LHK ,800 1:10 1:10 27 Osteopontin (OPN) LHK ,200 1:10 1:10 28 RBP4 LHK ,400 1:4,000 1:10 29 TFF3 LHK ,700 1:10 1:10 30 TIM-1/KIM-1/HAVCR LHK ,800 1:10 1:10 26 *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名 商品コード 価格 ( ) Human Kidney Biomarker Premixed Mag Luminex Perform Assay (1 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (2 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (3 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (4 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (5 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (6 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (7 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (8 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (9 PLEX) FCSTM ,000 Human Kidney Biomarker Premixed Mag Luminex Perform Assay (10 PLEX) FCSTM ,000 24

25 Performance Assay Human MMP Panel * Catalog # Analyte available exclusively from R&D Systems Analyte Magnetic Sensitivity/MDD (pg/ml) Human MMP Panel Base Kit LMP000B LMPM000 EMMPRIN LMP972 LMPM ,700 MMP-1 LMP901B LMPM ,300 MMP-2 LMP902C LMPM ,100 MMP-3 LMP513B LMPM ,700 MMP-7 LMP907B LMPM ,850 MMP-8 LMP908B LMPM ,700 MMP-9 LMP911B LMPM ,100 MMP-10 LMP910 LMPM ,000 MMP-12 LMP919B LMPM ,700 MMP-13 LMP511B LMPM ,000 Analyte Supernate Validated Samples and Recommended Starting Dilution Serum, Heparin Plasma, Platelet-poor Heparin Plasma Microparticle Region Saliva Urine Magnetic Human MMP Panel Base Kit EMMPRIN 1:5 1:5** 1:40 1: MMP-1 1:5 1:5 1:40 1: MMP-2 N/R 1:50 1:40 1: MMP-3 1:5 1:5 1:40 1: MMP-7 1:5 1:5 1:40 1: MMP-8 1:5 1:50 1:40 1: MMP-9 1:5 1:50*** 1:40 1: MMP-10 1:5 1:5 1:40 1: MMP-12 1:5 1:50 1:40 1: MMP-13 1:5 1:5**** 1:40 1: *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. **When assaying serum and plasma samples, EMMPRIN cannot be multiplexed with MMP-7, MMP-8, MMP-10, MMP-12, or MMP-13 ***MMP-9 is present in platelet granules and released upon platelet activation. Therefore, to measure circulating levels of this factor, platelet-free plasma should be collected for measurement. ****Heparin plasma and platelet-poor heparin plasma are not recommended for use with the MMP-13 assay. N/R=This sample type is not recommended for use in this assay 品名商品コード価格 ( ) Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (1 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (2 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (3 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (4 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (5 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (6 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (7 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (8 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (9 PLEX) FCST ,000 Human MMP Custom Premix Fluorokine MAP Kit, 1 Plate (10 PLEX) FCST ,000 Human MMP Premixed Magnetic Luminex Performance Assay (1 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (2 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (3 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (4 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (5 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (6 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (7 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (8 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (9 PLEX) FCSTM ,000 Human MMP Premixed Magnetic Luminex Performance Assay (10 PLEX) FCSTM ,000 25

26 Performance Assay Human Obesity Panel * Analyte Catalog # Human Obesity Panel Base Kit Sensitivity/MDD (pg/ml) Validated Samples and Recommended Starting Dilution Supernates Serum, EDTA Plasma, Heparin Plasma Microparticle Region LOB000 Adiponectin/Acrp30 LOB ,800 None 1:100 2 C-Reactive Protein LOB ,300 None 1:100 8 CCL2/MCP-1 LUH ,650 None 1:4 78 Complement Factor D/ Adipsin LOB ,600 None 1: IL-6 LUH ,240 None 1:4 32 IL-10 LUH ,250 None 1:4 50 Leptin LUB ,400 None 1:4 31 Resistin LOB ,300 None 1:4 12 Serpin E1/ PAI-1 LOB ,000 None 1: TNF- LUH ,570 None 1:4 77 *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名 商品コード 価格 ( ) Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (1 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (2 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (3 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (4 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (5 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (6 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (7 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (8 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (9 PLEX) FCST ,000 Human Obesity Custom Premix Fluorokine MAP Kit, 1 Plate (10 PLEX) FCST ,000 Rat Kidney Toxicity Panel * Analyte Catalog # Rat Kidney Toxicity Base Kit Sensitivity/MDD (pg/ml) Validated Samples and Recommended Starting Dilution Serum, EDTA Plasma, Urine Microparticle Region LRK000 Cystatin C LRK ,800 1: FABP1/L-FABP LRK ,469 1,800,000 1:4 31 Lipocalin-2/NGAL LRK ,550 1: TIM-1/KIM-1/HAVCR LRK ,900 1:4 25 Osteopontin/OPN LRK ,150 1: *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the Base Kit. 品名商品コード価格 ( ) Rat Kidney Toxicity Custom Premix Fluorokine MAP Kit, 1 Plate (1 PLEX) FCST ,000 Rat Kidney Toxicity Custom Premix Fluorokine MAP Kit, 1 Plate (2 PLEX) FCST ,000 Rat Kidney Toxicity Custom Premix Fluorokine MAP Kit, 1 Plate (3 PLEX) FCST ,000 Rat Kidney Toxicity Custom Premix Fluorokine MAP Kit, 1 Plate (4 PLEX) FCST ,000 Rat Kidney Toxicity Custom Premix Fluorokine MAP Kit, 1 Plate (5 PLEX) FCST ,000 26

27 Performance Assay Human TIMP 4-plex * Catalog # Analyte Magnetic TIMP-1 Sensitivity/ MDD (pg/ml) Range* Supernates (pg/ ml) Serum, EDTA Plasma, Heparin Plasma Urine Saliva Human Milk Microparticle Region Magnetic ,900 1:10 1:50 1:5 1:100 1: TIMP ,000 1:10 1:50 1:5 1:100 1: LKT003 LKTM003 TIMP ,000 1:10 1:50 1:5 1:100 1: TIMP ,000 1:10 1:50 1:5 1:100 1: *A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the kit. 品名商品コード価格 ( ) Human TIMP Luminex Performance Assay 4-plex Kit LKT ,000 Human TIMP Magnetic Luminex Performance Assay 4-plex Kit LKTM ,000 Human Adhesion Molecule 4-plex * Analyte Catalog # ICAM-1 Sensitivity/MDD (pg/ml) Supernates Serum, EDTA Plasma, Heparin Plasma Microparticle Region ,000 None 1:10 18 E-Selectin ,700 None 1:10 39 LKT007 P-Selectin ,200 None 1:10 4 VCAM , ,700 None 1:10 35 * A standard curve must be generated each time an assay is run utilizing values from the Standard Value Card included in the kit. 品名商品コード価格 ( ) Human Adhehesion Molecule Fluorokine MAP 4-plex Kit LKT ,000 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) 27

28 R&D Systems Luminex Assay のご注文について R&D Systems 社のウェブサイト Luminex Assay Online Configuration Tool にてご希望の因子をご選択いただき, Ref# を取得の上, 当社受託 特注品業務担当までお問い合わせ下さい ご注文までの流れ R&D Systems 社のウェブサイト ( 下記 URL) にアクセスし, お求めの製品の特長について選択肢をクリックしていきます Assay Type Screening Beads Type Performance Beads Type Magnetic Magnetic Species Species Species Species Human Mouse Rat Human Mouse Rat Human Rat Human Analyte を選択 Ref# を取得 Ref# を取得された後は, 当社受託 特注品業務担当まで, ご連絡下さい (Ref# の取得方法にご不明な点がある場合も, お問い合わせ下さい ) NOTE 本紙に掲載されている価格は,2015 年 4 月 20 日現在です 本紙に掲載されている製品はすべて研究用です 臨床用途には使用できません 仕様は改善のため, 予告なく変更することがあります R&D Systems は, テクネコーポレイションの登録商標です 本文中 # 以下の英数字は, 商品コードを示しています 記載されている会社及び商品名は, 各社の商標または登録商標です 表示価格には消費税等は含まれていません また価格は予告なく変更される場合がありますので, あらかじめご了承下さい ご注文の際は, 品名, メーカー (RSD), 商品コード, 包装, 数量 をお知らせ下さい 販売店 フナコシ株式会社 東京都文京区本郷 2 丁目 9 番 7 号 info@funakoshi.co.jp 受託 特注品業務担当 テクニカルサポート ( 試薬担当 ) ZF-Y04T-22