Effect of Sympathetic and parasympathetic agents on cholesterol metabolism in mice salivary glands. Eriko, NEZU and Haruo, NAKAMURA (Department of Ora

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1 Effect of Sympathetic and parasympathetic agents on cholesterol metabolism in mice salivary glands. Eriko, NEZU and Haruo, NAKAMURA (Department of Oral Physiology, Hokkaido University School of Dentistry, Sapporo.) Jap. J. oral Biol., 19: , 1977.

2 Fig. 1 Salivary gland weight after repeated injection for 7 days with agents. M }SE) N=6 cholesterol. (M }SE) N=6 Fig. 2 Effect of repeated injection for 7 days with agents on level of total

3 Fig. 3 Effect of repeated injection for 7 days with agents on the incorporation of acetate-1-14c into sterol. (M }SE) N=6 Fig. 5 Effect of repeated injection for 7 days with agents on the incorporation of mevalonate-3h into sterol. (M }SE) N=6 Fig. 4 Effect of repeated injection for 7 days with agents on the incoporation of HMG-14C into sterol. (M SE) N=6 }

4 Fig. 6 Effect of various agents administration.

5 Fig. 7 Effect of various agents on the incorporation of acetate-1-14c into sterol in vitro. (M }SE) N=4 Fig. 8a Time course for radioactivity after injection of cholesterol-7-8h. Fig. 8b Effect of repeated injection for 7 days with agents on the rate of disappearance of cholesterol-4-14c. (M }SE) N=5

6 Fig. 9 Effect of repeated injection for 7 days with agents on the rate of disappearance of cholestero1-4-14c. (M }SE) N=5

7 olism in mouse salivary glands. J. Biochem. 75: , ) YAMAMOTO, I., INOKI, R. and KOJIMA, S.: Adrenergic receptors in amylase secretion from rabbit parotid gland. European J. Pharmacol. 3: , ) DREISBACH, R. H.: Effect of isoproterenol on calcium metabolism in rat salivary gland. Proc. Soc. Exp. Biol. Med. 116: 953, ) EMMELIN, N. and STROMBLAD: Effect of guanethidine on salivary gland. Experientia (Basel) 19: , ) ZAK B.: Simple rapid microtechnic for serum total cholesterol. Amer. J. Clin. Path 27: , ) BUCHER, N. L. R. and MCGARRAHAN, K.: The biosynthesis of cholesterol from acetate- 1-14C by cellular fraction of rat liver. J. Biol. Chem. 222: 1-15, ) BARKA, T.: Stimulation of DNA synthesis by isoproterenol in the salivary gland. Exptl. Cell. Res. 39: , ) RODWELL V. W., MCNAMARA, D. J. and SHAPIRO, D. J.: Regulation of hepatic HMG-CoA reductase. Advan. Enzymol. 38: , ) DIETSELY, J. M. and WILSON, J. D.: Re- gulation of cholesterol metabolism. New Engl. J. Med. 282: , , , ) FEX, G. and WALLINDER, L.: Liver and plasma cholesteryl ester metabolism after partial hepatectomy in the rat. Biochim. Biophys. Acta 316: 91, ) TIBER, A.: Effect of pilocarpine on protein synthesis in the hamster submandibular gland. J. dent. Res., 49: 1551, ) INOUE, H., TANIOKA, H., SHIBA, K,. As- ADA, A., KATO, Y. and TAKEDA, Y.: Effect of isoproterenol on polyamine metab- 12) TAKEUCHI, N., KATAYAMA, Y., MATSUM- IYA, K., UCHIDA, K. and YAMAMURA, Y.: Feed-back control of cholesterol synthesis in partially hepatectomized rats. Biochim. Biophys. Acta 450: 57-68, ) YAMAMOTO, M. and YAMAMURA, Y.: Changes of cholesterol metabolism in the ageing rat. Atherosclerosis 13: , 1971.

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