Short Review Database Center for Life Science Online Service bicoid oskar mrna. gurken mrna bicoid mrna Tamaki Yano,
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1 Short Review bicoid oskar. gurken bicoid Tamaki Yano, tyanoc@mail.pharm.tohoku.ac.jp Maternal RNA localization and RNP-complex, essential for the polarization of the oocyte in Drosophila
2 hunchback oskar nanos hunchback bicoid oskar gurken gurken gurken
3 hicoid experantia bicoid bicoid bicoid experantia
4 experantia bicoid bicoid bicoid experantia experantia bicoid Experantia hicoid mrn A Experantia bicoid Experantia bicoid Experantia Par 1, bicoid Experantia bicoid bicoid swallow (y-tub37c ) bicoid bicoid bicoid bicoid bicoid oskar oskar oskar oskar oskar oskar Staufen 0) oskar oskar Y 14/Tsunagi16. 17), Magonashi 18), eif4a * 1 EJC : exon-exon junction complex
5 oskar oskar oskar oskar oskar oskar 2. oskar oskar RNA oskar oskar oskar oskar oskar - - oskar oskar oskar oskar (Bruno response element) arrest) Bruno oskar oskar oskar oskar hrp 48 oskar oskar oskar - oskar oskar oskar oskar oskar oskar oskar gurken
6 1) Riechmann, V., Ephrussi, A. : Curr. Opin. Genet. Dev., 11, (2001) 2) Kloc, M., Zearfoss, N. R., Etkin, L. D.: Cell, 108, (2002) 3) Job, C., Eberwine, J. : Nature Rev. Neurosci., 2, (2001) 4) Ephrussi, A., St Johnston, D. : Cell, 116, (2004) 5) Ephrussi, A., Dickinson, L., Lehmann, R.: Cell, 66, (1991) 6) Kim-Ha, J., Smith, J. L., Macdonald, P. M.: Cell, 66, (1991) 7) Anderson, K. V. : Cell, 95, (1998)
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Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,
TRANSPORTSOME NEWSLETTER
TRANSPORTSOME QUARTERLY Winter 2009 1 2 3 4 5 6 Synaptobrevin, Synaptotagmin, rab3 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Dev Cell 2002, Curr Opin Cell Biol 2006, J Cell Biol 2008, Curr
drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:
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1) Araki, T.: Curr. Opin. Plant Biol., 4, 63-68 (2001) 2) Boss, P. K., Bastow, R. M., Mylne, J. S., Dean, C.: Plant Cell, 16, S18-S31(2004) 3) Simpson, G. G., Dean, C. : Science, 296, 285-289 (2002) 4)
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Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo
Generation of neural cells from embryonic stem cells Takuya Yohei Okada Takahito Hideyuki Shimazaki Yoshizaki* Okano McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence
Review Column 1) Extavour, C. G., Akam, M. : Development, 130, 5869-5884 (2003) 2) Saitou, M. et al.: Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358,1363-1370(2003) 3) Eddy, E. M. : Int. Rev.
Vol.53 No. 11 (2008) 1327
Molecules that regulate morphology of the plasma membrane Shiro Suetsugu, Kazunori Takano E-mail : suetsugu@iam.u-tokyo.ac.jp 1326 Vol.53 No. 11 (2008) Vol.53 No. 11 (2008) 1327 1328 Vol.53 No. 11 (2008)
Stress-responsive MAP kinases 15) Lu, H. T., Yang, D. D., Wysk, M., Gatti, E., Mellman, I., Davis, R. J., Flavell, R. A. : EMBO J., 18,1845-1857 (1999) 16) Lu, B., Yu, H., Chow, C., Li, B., Zheng,
Spatio-temporal regulation of ERK1/2 MAP kinase 20) Murphy, L. 0., MacKeigan, J. P., Blenis, J.: Mol. Cell. Biol., 24, 144-153 (2004) 21) Harada, T., Morooka, T., Ogawa, S., Nishida, E.: Nature Cell
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Review Yoshihiro Yoneda, Soo Jae Lee, E-mail : yyoneda@anat3.med.osaka-u. ac.jp http: //www.anat3.med.osaka-u.ac.jp/ Molecular basis of importin g revealed by crystal structures 2) Yoneda, Y. : Genes
Short Review Hidenori Takagi, Fumio Takaiwa, E-mail : takaiwa@nias.affrc.go.jp 13) Hirahara, K. et al. : J. Allergy Clin. Immunol., 102, 961-967 (1998) 14) Takagi, H. et al.: Proc. Natl. Acad. Sci.
E-mail : tmatsumo@house.rbc.kyoto-u.ac.jp htm Spindle checkpoint : Cell cycle regulation by a signal emitted from kinetochores http://www.rbc.kyoto-u.ac.jp/radiation_system/m-index. 19) Yao, X., Abrieu,
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Complex sleep apnea syndrome and sleep disordered breathing in patients with cardiovascular disease V o l. 4 1 N o. 3 ( 2 0 0 9 ) V o l. 4 1 N o. 3 ( 2 0 0 9 ) V o l. 4 1 N o. 3 ( 2 0 0 9 ) Sleep J Clin
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Database Center for Life Science Online Service Chiharu Ueguchi, Molecular mechanism and biological function of t
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[Arabidopsis thaliana (L.) Heynh] E-mail : tsukaya@nibb. ac. jp http://www. nibb. ac. jp/~bioenv2/ Mechanisms of development in plants SHOOT (STM)3) WUSCHEL (WUS )4) MERISTEMLESS CUP-SHAPED COTYLEDON1,
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Review Fumio Imamoto1, Takefumi Sone1, Kazuhide Yahata1, Yukari Sasaki1, Masatoshi Takagi2, Kazuhiro Maeshima2, Naoko 25) Dong, W. K. et al.: Gene, 91, 217-223 (1990) 26) Masatsugu, T. et al.:
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DEIM Forum 2009 D2-1 COPINE: 112 86 2 1 1 E-mail: {seki,sesejun}@sel.is.ocha.ac.jp COPINE COPINE: Mining Networks Sharing Common Patterns Mio SEKI and Jun SESE Graduate School of Humanities and Sciences,
Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge
Review Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge E-mail : m.mishima @gurdon.cam.ac.uk http://www.gurdon.cam.ac.uk/groups/mishima.html Cytokinesis :
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1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, 193-2040982) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, 6762-6769(1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86,
Establishment and progress of Sendai virus engineering 2) Schnell, M. J., Mebatsion, T., Conzelmann, K.-K.: EMBO J., 13,4195-4203(1994) 3) Kato, A. et al.: Genes Cells, 1, 569-579 (1996) 4) Nagai,
Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara,
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Roles and regulations of an Arabidopsis homeobox gene, GL2 in epidermal cell development TRANSPARENT TESTA GLABRAI (TTGI ) CAPRICE (CPC), TRIPTYCHON (TRY) AtmybL 2 ATMYB 23 CPC, AtmybL 2 WEREWOLF (WER
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1) Bittner, J. J.: Science, 84, 162 (1936) 13) Michalides, R., van Ooyen, A., Nusse, R.: Curr. Top. Microbiol. Immunol., 106, 57-74 (1983) 2 z Yamamoto, K. R.: Ann. Rev. Genn., 19, 209-252 (1985) 3) Evans,
Short Review E-mail : kuwata@cc.gifu-u.ac.jp Structural medicine and structure-based drug design for prion diseases 2) Anfinsen, C. B.: Harvey Lect., 61, 95-116 (1967) 3) Carrel, R. W., Lomas, D. A.
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Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie
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Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing
Discovery, analysis and chemical mechanism of protein splicing VMA1 VMA1 2) Anraku, Y.: Genes to Cells, 2, 359-367 (1997) 3) Perler, F. B.: Cell, 92,1-4 (1998) 4) Perler, F. B.: Trends Biochem.
Novel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,
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2007 Vol.56 No.6 総説 丸山浩樹
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四 細胞生物学 八月 東京大学理学部生物化学科卒業 すけ 昭和二八年 東京大学大学院理学系研究科博士課程修了 介 昭和五一年 理学博士 えい 日本学術振興会奨励研究員 栄 東京大学理学部助手 だ 六月 京都大学ウイルス研究所教授 田 五月 京都大学大学院理学研究科教授 にし 五年 京都大学大学院生命科学研究科教授 現在に至る 西 平成 九年 京都大学大学院生命科学研究科長 平成二一年まで 受賞者 専攻学科目
9) McKenna, N. J., O'Malley, B. W. : Cell, 108,465-474 (2002) 10) Hu, X., Lazar, M. A. : Nature, 402, 93-96 (1999) 11) Lanz, R. B., McKenna, N. J., Onate, S. A., Albrecht, U., Wong, J., Tsai, S. Y., Tsai,
Database Center for Life Science Online Service archlaboratories, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki-shi, Kanagawa 213, Japan] Developmental Genetics of Caenorhabditis elegans Database Center for
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Structure and function of nitric oxide synthases 3) Furchgott, R. F., Zawadzki, J. V. : Nature, 288,373-376 (1980) 4) Palmer, R. M., Ferrige, A. G., Moncada, S.: Nature, 327,524-5260987) 5) Alderton,
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図 1 ヘテロクロマチン化および遺伝子発現不活性化に関わる因子ヘテロクロマチン化および遺伝子発現不活性化に関わる DNA RNA タンパク質 翻訳後修飾などを示した ヘテロクロマチンとして分裂酵母セントロメアヘテロクロマチンと哺乳類不活性 X 染色体を 遺伝子発現不活性化として E2F-Rb で制御
第 2 章エピジェネティクスと遺伝子発現制御機構 6. ヘテロクロマチン化の分子機構 定家真人, 中山潤一 ヘテロクロマチンは DNA RNA タンパク質からなる高度に凝縮した構造であり 真核生物染色体の維持に必須の領域であるセントロメア テロメアの機能に重要な役割を果たしている 分子レベルの詳細な研究により ヘテロクロマチン化に関わる分子群およびその機構は 発生 分化や細胞周期などに依存した遺伝子特異的な発現の不活性化と共通点が多いことが明らかにされてきた
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Parkin Parkin C RING IBR in-between-ring fingers RBR RING-IBR-RING Parkin E Parkin E Parkin RBR Parkin Parkin E E E E E ATP C E How E activity of Parkin is enhanced by damaged mitochondria Fumika Koyano
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