xxxxEN.qxd
|
|
- れれ おいもり
- 5 years ago
- Views:
Transcription
1 Ultron ES-VM : HPLC HPLC 28,000, 1-120Å 5-µm Ultron ES-VM [1-] Ultron ES-VM HPLC ph pi Ultron ES-VM ph pi ph pka = 4.4 ph pka = k' 1 αph 1 Ibuprofen H3 C CHCH 2 CH CH H 3 C Chlorpheniramine pka = 4.4 H3 C H 3 C CHCH 2 CH C _ Cl + H C H + CH 2 CH 2 H pka = 4.0 Cl C H + CH 2 CH 2 H pka = 9.2 Cl C H CH 2 CH 2 Hexobarbital _ H 3 C H pka = 8.2 H 3 C 1.
2 20 mm 0/5 ph k' 1 α= k' 2/k' ph 3.0 ph pH ph k' 1 2 phk' 1 ph 3.0 phpi 3α ph α ph 2 α k Enantiomeric samples Ibuprofen Chlorpheniramine Hexobarbital ph 2 ph ph : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2P KH 4 2 (ph P 4 4.6)/C (ph 4.6)/C 2H 5H 2 H(0/20 5 H (0/20 v/v) v/v) : Pressure: 25 ºC1 kg/cm 2 : Temperature: UV C nm ph k' 2 ph k' 1pKa 4.4 ph ph k' 1 ph k' 1 ph 3.0 k' 1 ph 3. α ph Enantiomeric samples Ibuprofen Chlorpheniramine Hexobarbital 6 7 : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2P KH 4 2 (ph P 4 4.6)/C (ph 4.6)/C 2H 5H 2 H(0/20 5 H (0/20 v/v) v/v) : Pressure: 25 ºC1 kg/cm 2 : Temperature: UV C nm ph α 2
3 pka = 3.9pKa = ph mm / 0/ mmk' 5 mm k' 20 mm Ultron ES-VM k' α ph pka = 8.95 v/v > > > Acetonitrile Ethanol Enantiomeric samples First 1 chlorpheniramine Second 2 chlorpheniramine First 1 ketoprofen Second 2 ketoprofen Isopropanol Methanol k Phosphate (mm) buffer 80 Time (min) Time (min) Time (min) Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm (ph 20 phosphate buffer 4.6)/ (0/ (ph 5.5)/ethanol v/v) : 1.0 ml/min (0/ v/v); buffer concentration = 5,, 70 : Flow rate: 25 ºC1.0 ml/min : Pressure: UV nm kg/cm 2 Temperature: 25 C : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm (ph 20 phosphate buffer 4.6)/ (0/ (ph 4.6)/organic modifier v/v) : 1.0 ml/min (0/ v/v) : Flow rate: 25 ºC1.0 ml/min : Pressure: UV nm kg/cm 2 Temperature: 25 C
4 1 5 v/v 0/5 0/ v/v 20 mm ph 4.6 k' 2 k' [5] 1. Ultron ES-VM 5 5 k 1 α k 1 α k 1 α k 1 α a a a a 20 mmph 4.6 v/v 2. k 1 α k 1 α a a a a 20 mmph 4.60/ v/v0/7 v/v b 20 mmph 5.50/ v/v0/8 v/v c 20 mmph 6.00/5 v/v0/4 v/v 4
5 Ultron ES-VM 20 mm ph 4.60/ v/v k' α Rs k' α 19 ES-VM 3. a 5 C 11 C 19 C 28 C 40 C k k α R s a 20 mmph 4.60/ v/v Ultron ES-VM 6 ph mm /0/20 v/v18 25 α ph mm / 0/ v/v 15 7 [8] 18 C 22 C 25 C t 1 = 9.65 t 1 = 8.28 t 1 = 7.29 t 2 = t 2 = t 2 = Time (min) Time (min) Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm (ph 20 phosphate buffer 4.6)/ (0/20 (ph 4.6)/acetonitrile (0/20 v/v) v/v) : Pressure: 18,22,25ºC 1 kg/cm 2 : Temperature: UV-220 Varied nm 6. HPLCUltron ES-VM mm Ultron ES-VM µl mm Ultron ES-VM nmol/g [5] 2 nmol 1 µg HPLC 1 50 µl 25 µl [4] HPLC k' k' 5
6 Sample loading amount 0.75 µg 1.5 µg 5 µg µg 15 µg 20 Time (min) : Ultron ES-VM : Column: Ultron mm ES-VM : Column size: 20 mm 4.6 KH 150 mm 2P 4 (ph 5.5)/C 2H 5H (0/4 v/v) : Mobile phase: 1.0 ml/min 20 mm KH 2 P 4 (ph 5.5)/C 2 H 5 H (0/4 v/v) Flow rate: 1.0 ml/min : Temperature: Ambient : UV-220 nm : 5-uL Injection volume: 5-uL loop : Sample: Tolperison 7. HPLC 2 Ultron ES-VM ml/min Plate height cm cm mm id 6.0 mm id Mobile phase flow rate 8. Ultron ES-VM 150 mm 6
7 Ultron ES-VM mm [5] ph 3.0α ph pH ph 4.0 ph 4.6 ph M (ph 3.0) () ( ) ph 4.0 1) ( 50%) 2) ( ) () 1) 2) ( ) ph 4.0 ( ) () 0.02 M (ph 4.6) () ( ) ph ) ( 50%) 2) ( ) () 1) 2) ( ) ph ( ) () : 2- (20 mm):kh 2P 4/K 2HP 4 HCH/HCH 4 CH/Ca C 3H 4H(CH) 3KH 2P 4 7
8 49 43 Ultron ES-VM Ultron ES-VM Rs 20 mm (ph 4.6)- (0/7.5 v/v) mm (ph 4.6)- (0/25 v/v) 6.06 Bay K mm (ph 4.6)- (0/25 v/v) mm (ph 4.6)- (0/20 v/v) mm (ph 4.6)- (0/ v/v) mm (ph 4.6)- (0/ v/v) mm (ph 6.0)- (0/3 v/v) mm (ph 5.5)- (0/ v/v) mm (ph 4.6)- (0/ v/v) mm (ph 5.5) mm (ph 5.0)- (0/5 v/v) mm (ph 5.5)- (0/3 v/v) mm (ph 4.6)- (0/15 v/v) mm (ph 4.6)- (0/15 v/v) ,2-20 mm (ph 5.5) mm (ph 5.5)- (0/ v/v) mm (ph 5.5)- (0/5 v/v) mm (ph 4.6) mm (ph 3.0)- (0/30 v/v) mm (ph 4.6)- (0/ v/v) mm (ph 4.6) mm (ph 5.5)- (0/5 v/v) mm (ph 4.6)- (0/ v/v) mm (ph 4.6)- (0/15 v/v) mm (ph 3.0)- (0/ v/v) mm (ph 3.0)- (0/ v/v) mm (ph 4.6)- (0/35 v/v) mm (ph 4.6) mm (ph 4.6)- (0/ v/v) mm (ph 5.7) mm (ph 5.5)- (0/ v/v) mm (ph 5.5)- (0/3 v/v) mm (ph 3.0)- (0/8 v/v) mm (ph 5.0)- (0/15 v/v) mm (ph 4.6)- (0/25 v/v) mm (ph 4.6)- (0/20 v/v) mm (ph 4.6)- (0/20 v/v) mm (ph 6.8)- (0/30 v/v) mm (ph 5.5)- (0/30 v/v) mm (ph 5.5)- (0/ v/v) mm (ph 4.6)- (0/ v/v) mm (ph 4.6)- (0/30 v/v) mm (ph 4.6)- (0/5 v/v)
9 ph Ultron ES-VM Ultron ES-VM mm 1. T. Miwa, T. Miyakawa, and M. Kayano, Chem. Pharm. Bull., 35 (1987) T. Miwa, T. Miyakawa, and M. Kayano, J. Chromatogr., 408 (1987) M. kamoto and H. akzawa, J. Chromatogr., 504 (1990) Y. Hu and D. Kupfer, Drug Metabolism and Disposition, 30 (2002) K. M. Kirkland, K. L. eilson, D. A. McCombs, and J. J. DeStefano, LC-GC, (1992) K. Ishii, S. Wakamoto, H. akai, and T. Sata, Chromatographia, 43 (1996) K. M. Kirkland, K. L. eilson, and D. A. McCombs., J. Chromatogr., 545 (1991) Y. Hu and D. Kupfer, Drug Metabolism and Disposition, 30 (2002) J. Haginaka, J. Wakai, K. Takahashi, H. Yasuda, and T. Takagi, Chromatographia, 29 (1990) P. Bonato, R. Bortocan, C. Gaitani, F. Paias, M. Ina, and R. Lima, J. Braz. Chem. Soc., 13 (2), S CH2 CH 20 Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2P KH 4 2 (ph P 4 = (ph 4.6)/C = 4.6)/C 2H 5H 2 H= 5 H 0/20 = 0/20 v/v v/v : Pressure: 25 ºC1 kg/cm 2 : Temperature: UV nm C. 9
10 Antiinflammatory Fenoprofen calcium _ C CH Ca 3+ 2H 2 () Cholinergic blocking (parasympatholytic) drugs Mepenzolate bromide C C Br _ Antiinflammatory Pranoprofen CH CH H + H 3 C Time (min) Column: Ultron ES-VM : Ultron ES-VM Column size: mm : mm Mobile phase: 20 mm KH 2 P 4 (ph 5.6)/ : 20 mm KH C 2 H 5 H 2P (0/ 4 (ph 5.6)/ v/v) C Flow rate: 2H 5H (0/ v/v) 1.0 ml/min : 1.0 ml/min Temperature: 27 C : Detection: 27 ºC UV-220 nm (0.04 AUFS) : UV-220 nm (0.04 AUFS) Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2P KH 42 P (ph 4 (ph = 4.6) = 4.6) : Temperature: 27 ºC27 C : Detection: UV-220 UV-220 nm (0.04 nm (0.04 AUFS) AUFS) Time (min) Column: Ultron ES-VM : Column size: Ultron 4.6 ES-VM 150 mm : Mobile phase: mm mm KH 2 P 4 (ph 6.0)/ : 20 mm C 2 H KH 5 H 2P (0/5 4 (ph 6.0)/ v/v) Flow rate: C 2H 5H 1.0 (0/5 ml/min v/v) : Temperature: 1.0 ml/min 27 C : Detection: 27 ºC UV-220 nm (0.04 AUFS) : UV-220 nm (0.04 AUFS) Antihistamines Promethazine hydrochloride Local Anesthetic Bupivacaine Antiparkinson drugs Trihexyphenidyl S CH 2 CH 2 C H HCI CH 2 CH HCI H C (CH 2 ) 3 20 Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2P KH 42 (ph P 4 4.6)/ (ph 4.6)/ C 2H 5H C 2 H 5 (0/20 H (0/20 v/v) v/v) : Temperature: Ambient : Detection: UV-220 UV-220 nm (0.04 nm (0.04 AUFS) AUFS) 20 Time (min) Column: : Ultron Ultron ES-VM ES-VM Column : size: mm 150 mm Mobile : phase: 20 mm 20 mm KH 2P KH 42 P (ph 4 (ph 5.5)/ 5.5)/ C C (0/ (0/ v/v) v/v) Flow : rate: 1.0 ml/min 1.0 ml/min Temperature: : 25 ºC25 C Detection: : UV-220 UV-220 nm (0.04 nm (0.04 AUFS) AUFS) 5 Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2P KH 4 2 (ph P 4 4.6)/ (ph 4.6)/ C 2H 5H C 2 H(0/ 5 H (0/ v/v) v/v) : Temperature: Ambient : Detection: UV-220 UV-220 nm (0.04 nm (0.04 AUFS) AUFS)
11 Antipsychotics Thioridazine hydrochloride Diuretic drugs Ethiazide Skeletal muscle relaxants Eperisone hydrochloride S S CH 2 CH 2 H 2 Cl S H S H C2H 5 C H H 3 CH 2 C C CH CH 2 HCl HCI Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2PKH 4 (ph 2 P5.5)/ 4 (ph 5.5)/ C CH(0/30 3 C (0/30 v/v) v/v) : Temperature: 31 ºC 31 C : Detection: UV-254 UV-254 nm (0.04 nm AUFS) (0.04 AUFS) 20 Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2PKH 4 (ph 2 P 4.6) 4 (ph 4.6) : Temperature: 25 ºC25 C : Detection: UV-220 UV-220 nm (0.04 nm (0.04 AUFS) AUFS) 20 Time (min) : Column: Ultron Ultron ES-VM ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2P KH 4 (ph 2 P5.5)/ 4 (ph 5.5)/ C 2H 5H C 2 H(0/5 5 H (0/5 v/v) v/v) : Temperature: 25 ºC 25 C : Detection: UV-220 UV-220 nm (0.04 nm AUFS) (0.04 AUFS) 1,2-1,2-Diphenylethylamine Prenylamine lactate 2-2-Phenyl propionic acid CH (CH 2 ) 2 H CH CH 2 H 3 C CH CH CH 2 CH H Time (min) Time (min) Column: Ultron ES-VM Column : size: Ultron 4.6 ES-VM 150 mm Mobile : phase: mm mm KH 2 P 4 (ph 5.5) Flow : rate: 20 mm 1.0 ml/min KH 2P 4 (ph 5.5) Temperature: : 1.0 ml/min 25 C Detection: : 25 ºC UV-220 nm (0.04 AUFS) : UV-220 nm (0.04 AUFS) Column: Ultron ES-VM Column size: mm : Ultron ES-VM Mobile phase: 20 mm KH 2 P 4 (ph 5.0)/ : mm C (0/15 v/v) : 20 mm KH 2P 4 (ph 5.0)/ Flow rate: 1.0 ml/min C (0/15 v/v) Temperature: 25 C : 1.0 ml/min (0.04 AUFS) : 25 ºC : UV-220 nm (0.04 AUFS) 20 Time (min) : Column: Ultron ES-VM Ultron ES-VM : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2 P 4 (ph 4.6) KH2P4 (ph 4.6) : Temperature: 25 ºC 25 C : Detection: UV-220 UV-220 nm (0.04 nm AUFS) (0.04 AUFS) 11
12 () rnidazol (Antibiotic) a 2 P a () Bicalutamide (Antiandrogen) CF 3 H 3 C F S 2 CH 2 C C C H H aftopidil (Alpha1a-adrenergic (α1a-) receptor antagonist) H CH 2 CHCH 2 H 3 C Minute Column: Ultron ES-VM (5 µm) : Ultron ES-VM (5 µm) Column size: mm : mm Mobile phase: 20 mm KH 2 P 4 (ph 3.0)/ : 20 mm KH C 2P (88/12 4 (ph 3.0)/ v/v) CH Flow rate: 3C (88/12 v/v) 1.0 ml/min : 1.0 ml/min Temperature: 25 C : 25 ºC Sample: : UV-220 rnidazol nm disodium phosphate : 0.2 mg/ml Injection vol: 0.2 mg/ml 3 µl : 3 µl Minute : Column: Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) : Column size: mm 150 mm : Mobile phase: 20 mm 20 mm KH 2P KH 42 (ph P 4 4.6)/ (ph 4.6)/ C (88/12 C (88/12 v/v) v/v) : Temperature: 25 ºC25 C : Detection: UV-220 UV-220 nm nm : Sample: CH Bicalutamide in 33C 0.1 mg/ml 0.1 mg/ml : Injection vol: 3 µl3 µl Minute Column: : Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) Column : size: mm mm Mobile : phase: 20 mm 20 mm KH 2P KH 42 P (ph 4 (ph 7.0)/ 7.0)/ C (75/25 C (75/25 v/v) v/v) Flow : rate: 1.0 ml/min 1.0 ml/min Temperature: : 25 ºC 25 C Detection: : UV-220 UV-220 nm nm Sample: : 0.5 aftopidil mg/ml Injection : vol: 1 µl1 µl 20 Cetirizine hydrochloride ( ) (Antihistamine) Cl CH CH 2 CH 2 CH 2 CH 2HCI Fulvastatin sodium (HMG-CoA ) (HMG-CoA reductase inhibitor) H Ca F Amlodipine besilate (Calcium channel blocker) ( ) H CH 2 CH 2 CH 2 H 2 C CC 2 H Cl. S 3 H Minute Column: Ultron ES-VM (5 µm) : Column size: Ultron 4.6 ES-VM 150 mm (5 µm) : Mobile phase: mm mmkh 2 P 4 (ph 4.6)/ : 20 mm CHKH 3 C 2P (90/ 4 (ph 4.6) v/v) Flow rate: /C 1.0 ml/min (90/ v/v) : Temperature: 1.0 ml/min 25 C : Detection: 25 ºCUV-235 nm : Sample: : UV-235 Cetirizine nm hydrochloride 0.2 mg/ml mg/ml : Injection vol: 2 µl 2 µl Minute Column: : Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) Column : size: mm mm Mobile : phase: 20 mm 20 mm KH 2P KH 4 2 P (ph 4 (ph 3.0)/ 3.0)/ C C (88/12 (88/12 v/v) v/v) Flow : rate: ml/min ml/min Temperature: : 25 ºC 25 C Detection: : UV-235 UV-235 nm nm Sample: : Fulvastatin sodium 0.5 mg/ml 0.5 (Solvent: mg/ml ( : ) methanol) Injection : vol: 1 µl1 µl Minute Column: : Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) Column : size: mm mm Mobile : phase: mm mm a 2HP a 2 HP 4 (ph 4 (ph 7.0)/ 7.0)/ C CH (78/22 3 C (78/22 v/v) v/v) Flow : rate: 1.0 ml/min 1.0 ml/min Temperature: : 25 ºC 25 C Detection: : UV-237 UV-237 nm nm Sample: : 0.02 Amlodipine besilate mg/ml ( : ) 0.02 mg/ml (Solvent: Methanol) Injection : vol: 2 µl2 µl 12
13 Fexofenadine hydrochloride ( ) (Antihistaminic) Sodium rabeprazole ( ) (Proton pump inhibitor) H H C (CH 2 ) 3 CH C CH HCl H 2 CH 2 CH 2 CH 3 C CH 2 S a : Column: Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2P KH 4 (ph 2 P4.6)/ 4 (ph 4.6)/ C CH(95/5 3 C (95/5 v/v) v/v) : Temperature: 25 ºC25 C : Detection: UV-220 UV-220 nm nm : Sample: Fexofenadine hydrochloride 0.3 mg/ml 0.3 mg/ml : Injection vol: 1 µl 1 µl Minute : Column: Ultron Ultron ES-VM ES-VM (5 µm) (5 µm) : Column size: mm 150 mm : Mobile phase: 20 mm 20 KH mm 2P KH 4 (ph 2 P6.0)/ 4 (ph 6.0)/ C CH(95/5 3 C (95/5 v/v) v/v) : Temperature: 25 ºC25 C : Detection: UV-225 UV-225 nm nm : Sample: Sodium rabeprazole 0.2 mg/ml 0.2 mg/ml : Injection vol: 3 µl 3 µl 13
14 Agilent Technologies, Inc Printed in Japan July 11, JAJP
untitled
ULTRON No.4 Ver.2, ULTRON ES-OVM 1 2 2 2 3 3 4 ph 3 5 3 6 4 7 5 8 6 7 9 8 9 10 10 14 11 15-1 - 1. ULTRON ES-OVM 1.1 (1) (120 5µm) ( ) 63-307829 (2) (3) (4) ng 1.2,,, 2. (Ovomucoid) ph3.5 28,000 3.9 4.3
More informationMicrosoft PowerPoint - LCテクノ ポスター 塚本
HPLC,UHPLCそれぞれの視点から見たコアシェル型充填カラムと全多孔性充填カラムとの比較 塚本友康, 長江徳和 ( クロマニックテクノロジーズ ) 表面多孔性シリカ ( コアシェル ) 細孔のない核 ( コア ) と多孔質層から形成されているシリカ粒子であり 全多孔性シリカ粒子に比べ表面積は小さい 粒子全体に対する多孔質層の割合が 77% と高いため, 試料負荷量が低くなる欠点を克服 粒子細孔径が
More informationSEC (SEC) SEC SEC SEC 2
SEC (SEC) SEC SEC SEC 2 SEC ( 1) 1: SEC www.agilent.com/chem/jp 3 ( ) ( 2) ICH (Q6B) 3 lgg 8 7 6 5 4 1. 2. 3. 4. 5. Agilent AdvanceBio SEC 3 Å 7.8 x 3 mm 2.7 µm (p/n PL118-531) Agilent 126 Infinity LC
More informationAqua Way Philic Aqua Way Cation Technology platform Cell-sheet engineering (1) Technology platform Cell-sheet engineering (2) 1) Collection of cells in a form of thin film 2) o suture required for transplantation
More informationuntitled
HILIC ILIC BEH BEH 009 9 0 5 009 ihon Waters K.K. HILIC HILIC HILIC MS Sub-µm 009 ihon Waters K.K. HILIC? HILIC - Hydrophilic Interaction Chromatography 990 * HILIC (> 80%) *Alpert A. J. J.Chromatogr.
More informationバイアル新規ユーザー様限定 ガラス製容器 -Si-O H シラノール -Si-O H -Si O -Si イオン的吸着 疎水的吸着シロキサン logp pka + N 塩基性化合物 疎水的吸着 水溶液 P P 製容器, 7,7
P. P. P. LC P. GC P. P.7 GC P.8 GC ナツ 夏トク!! ワッショイ! SUMMER.7-.9 消耗品だいしょうもうひん まつり! 祭 Vol. バイアル新規ユーザー様限定 ガラス製容器 -Si-O H シラノール -Si-O H -Si O -Si イオン的吸着 疎水的吸着シロキサン logp pka + N 塩基性化合物 疎水的吸着 水溶液 P P 製容器, 7,7
More informationAgilent Infinity ELSD ELSD ( ) ( ºC ) W x D x H mm LED ELSD ELSD ELSD UV UV LC/MS RSD % Column: Agilent Pursuit C8, x.6 mm, µm Eluent: Water: Acetonit
Agilent Infinity ELSD Agilent 6 Infinity ELSD Agilent 9 Infinity ELSD 6 8 ELSD 9 LC/MS ELSD Agilent Infinity ELSD ELSD ( ) ( ºC ) W x D x H mm LED ELSD ELSD ELSD UV UV LC/MS RSD % Column: Agilent Pursuit
More informationCOSMOSIL.indd
Column: 5C 18 -MS-II Column size: 4.6mmI.D.-150mm Mobile phase: Methanol/ H 2 = 60/40 Detection: UV254nm Sample: 1; Acetophenone (0.05μg) 2; Methyl Benzoate (0.5μg) 3; Benzene (2.0μg) 4; Toluene (2.0μg)
More informationuntitled
(F76A) .% TFA/acetonitrile TFA ph acetonitrile -propanol TFA Triart YMC-Triart C8 / C8 YMC-Triart C8 / C8 C8 C8 ( ).9 µm 3 µm µm nm C8 % C8 7% ph - 7 for ph -7 for ph 7- YMC-Triart % of initial retention
More informationJP.qxd
Agilent ZORBAX Eclipse Plus LC LC Our measure is your success. products applications software services PAH? ZORBAX Eclipse Plus Eclipse Plus LC (PAH) C18 ZORBAX Eclipse Plus ZORBAX 2 ZORBAX Eclipse Plus
More information2 (FDA) 1 1 A D E K 1 LC UV 15 HPLC 3.5 UHPLC Agilent 12 Infinity LC Agilent 12 Infinity (G1311B) Agilent 12 Infinity (G13E) Agilent 12 Infinity (G131
1 Agilent 12 Infinity 1 Siji Joseph Agilent Technologies, Inc. Bangalore, India 12 1 2 4 5 3 2 1 4 1 12 14 4 2 Agilent 12 Infinity 2 4 5 3 2.5 1. 1.5 2. 2.5 3. 2 (RP-HPLC) Agilent Poroshell EC-C1 Agilent
More informationHPLC カラム 総合カタログ 2015
HPLC カラム 総合カタログ 201 HPLC ZIC -HILIC ZIC -chilic ZIC -philic Chromolith HighResolution RP-8e RP-8 RP-selectB Si Chromolith NH 2 CN DIL NEW Phenyl PAH PAH PEEK PEEK PEEK PEEK PEEK (µm) 3., 3 - - (Å 100,
More information薬物分析法の開発
API5000 TM LC/MS/MS Junichi_Hirokawa@trc.toray.co.jp 1. LC/MS/MS 2. 3. MS/MS 4. 5. API5000 6. 7. 8. 1. LC/MS/MS API 5000 AB/MDS Sciex UPLC API 4000 AB/MDS Sciex Agilent1100 PAL PAL ew wash 4000 QTRAP AB/MDS
More information橡マニュアルv4c.PDF
LC/MS MS LC/MS LC LC (APCI) (ESI) FAB 2 LC (APCI) 4.1.1.1 LC LC/MS LC MS LC 3 ph APCI/MS LC (1) APCI ESI 100% 100% ESI 4.1.1-1 LC 1.00cp 100 34 a 4.1.1-1 LC b ( /mpas) n- 0.23 36 0.5 99 0.31 69 n- 0.92
More informationh1_4.ai
For the Customer, and for Society. It s our Commitment. SynergiFusion-RP C8 C8 C8 C8 C5 C93.Phenylpropanolamine 3.Pseudoephedrine 3 : Synergi 4µ Fusion-RP : 5 x 4.6mm : mm Potassium Phosphate, p.5 / Methanol
More informationWaters Sigma-Aldrich 1.0 mg/ml LC Waters Alliance HPLC ACQUITY UPLC H-Class Bio 30 cm Alliance HPLC UV ACQUITY UPLC TUV mm nm XBridge Protein B
HPLC 3. µm BEH Stephan Koza, Susan Serpa, Hua Yang, Edouard Bouvier, and Kenneth J. Fountain Waters Corporation, Milford, MA, USA HPLC 200 0 HPLC 2 2010 UPLC 200 SEC 1 UPLC SE-UPLC 2 µm BEH BEH 100% SE-UPLC
More informationVOL. 25 NO. 6 CHEMOTHERAPY 1667
1666 CHEMOTHERAPY AUG. 1977 VOL. 25 NO. 6 CHEMOTHERAPY 1667 1668 CHEMOTHERAPY AUG. 1977 VOL. 25 NO. 6 CHEMOTHERAPY 1669 VOL. 25 NO. 6 CHEMOTHERAPY 1671 1672 CHEMOTHERAPY AUG. 1977 VOL. 25 NO. 6 CHEMOTHERAPY
More informationAgilent
Agilent Agilent CE Agilent Checklist CEC CE/MS Agilent CE CEC / CE/MS Agilent Agilent 10 High sensitivity detection cell 75 µm i.d. capillary Agilent CE Agilent Agilent CE Agilent CE/MS Agilent CE/MS Agilent
More informationJAJP.qxp
Agilent SPE SPE ...3...4...5...6...7...8 OPT...10 SCX...12 SAX...14 DVB...16 PS-DVB...17...18 C18EC...18 C18 ODS...19 C8...20 C2...21...21...22 (CN)...23...23...24 Si-SCX...25 Si-SAX...26...27 Florisil
More informationMicrosoft PowerPoint - TCI Dual ppt
~ミックスモードカラム ~ DS との違い 移動相の考え方 TCI Chromatography Department 逆相とミックスモード : 充填剤の違い DS カラムに用いる充填剤 オクタデシル基をシリカゲルに化学結合 ミックスモードカラムに用いる充填剤 オクタデシル基とイオン交換基両方を有する試薬をシリカゲルに化学結合 弊社製品は DS とイオン交換の充填剤を混ぜることはしておりません 疎水性部分
More informationA4冊子1P-P20.ai
REVERSE PHASE CLUMN GUIDE 1 2 Luna 5 μm Phenyl-Hexyl, 150x4.6 mm Luna 5 μm C8(2), 150x4.6 mm Luna 5 μm C18(2), 150x4.6 mm : 50:15:35 Methanol:Acetonitrile: 20mM Ammonium Formate ph 3.5 : 1.0 ml/min : 1.
More informationHPLC 1M KH 2 PO 4 ph ml Anthranilic acid: AnA 600 ml ml AnA 1.0 ml / min Anthranilic acid= PRESSURE 140 kgf / cm 2
15 10-1-3. 1. HPLC 1M KH 2 PO 4 ph 3.0 50 ml Anthranilic acid: AnA 600 ml 1-1. 350 ml AnA 1.0 ml / min Anthranilic acid=137.14 PRESSURE140 kgf / cm 2 TOSOH TSK-GEL ODS- 80 Ts 1) mg / ml AnA in (φ4.6 250
More information内容 1. セミ分取 HPLC システム 応用例 留意点 2. 超臨界流体クロマトグラフィー (SFC) を使用した分取の紹介
見れば得する! セミ分取システムの実用的な使い方 内容 1. セミ分取 HPLC システム 応用例 留意点 2. 超臨界流体クロマトグラフィー (SFC) を使用した分取の紹介 医薬品や天然物質などから 目的の化合物を高純度で単離 精製することを目的とした HPLC セミ分取 HPLC: 分取 HPLC とは カラム内径が 10mm 以上 50mm 未満のカラムを用いた分取 HPLC 分取 HPLC:
More informationC18 カラムのエンドキャッピングは ここまで進化した! 耐久性を実現する 技術とその性能 クロマニックテクノロジーズ塚本友康小島瞬長江徳和
C18 カラムのエンドキャッピングは ここまで進化した! 耐久性を実現する 技術とその性能 クロマニックテクノロジーズ塚本友康小島瞬長江徳和 Email: info@chromanik.co.jp http://chromanik.co.jp エンドキャッピング 塩基性化合物のピーク形状の改善 ピンポイントなエンドキャッピング 表面を覆うようなエンドキャッピング 手法 TMS 化 マルチステージタイプ
More informationMastro -リン酸基含有化合物分析に対する新規高耐圧ステンレスフリーカラムの有用性について-
学会発表資料 _ 抜粋 リン酸基含有化合物分析に対する新規高耐圧ステンレスフリーカラムの有用性について 佐藤友紀 1,3, 山口忠行 2, 尾坂裕輔 2, 山本祝久 1 ( 株式会社島津ジーエルシー 1, 株式会社島津製作所 2, 独立行政法人国立循環器病研究センター薬剤部 3) はじめに リン酸基含有化合物や 属キレート性のある化合物は, 分析を う際にテーリング現象や吸着現象が起こる事が一般的に知られている
More informationJAJP.qxp
Our measure is your success. products applications software services ...3...5...6...9...11...12...13 /...14...15 -V...16...16 8-425...17...18 4 ml...19...20 /...22 CombiPAL/GC PAL /...23 HTS/HTC PAL /...24...25...26...27
More informationAdenosine Triphosphate Adenosine Monophosphate min min Fig.2 Chromatograms of Nucleotides Peak
Hydrocortisone Sodium Phosphate 3.5 1.0 0.5 1 μg/ml 3.0 2.5 25 ng/ml 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 min 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 min Fig.1 Chromatograms of Hydrocortisone
More informationⅡ6.3界面活性剤
6.3 6.3.1 6.3.1 6.3.1.1 (1) (2) a) JIS K 0557 A3 b) JIS K 8891 c) (5g/L) d) (10g/L)JIS K 8576 1g 100mL e) (7+993)JIS K 8951 f) JIS K 8322 g) 0.1g 100mL 30mL 1L 500mL6.8mL 50g 1L h) 1L 500mL6.8mL 50g 1L
More information3 1 2
Agilent 4200 TapeStation Agilent 4200 TapeStation 3 1 2 2 3 ScreenTape 3 Agilent 4200 TapeStation QC Agilent 4200 TapeStation Ready-to-use ScreenTape 8 PCR 96-well plate 1 96 1 qrt-pcr DNA RNA DNA / RNA
More informationLC ACQUITY UPLC H-Class Bio TUV Sigma, mg/ml 0.01 N 276 nm μl 0.4 ml/min L g/l / 99% / 65/15/20 v/v/v 10% 10% 0.01 N ACQUITY
Ultra Performance Liquid Chromatography Stephan Koza, Paula Hong, and Kenneth J. Fountain Waters Corporation, 34 Maple Street, Milford, MA, USA & SEC 2010 2 8 5 2030 4 3 8 1982 2009 131 USP EPHMW USP34
More information中面 2 Hot News Vol 可能性 拡がる Nexera コアシェル リンク 3.6μmのコアシェルを用いれば アセトニトリル 水系で背圧10MPa 程度でご使用頂けます 1.7μm 2.6μm 3.6μm UFLC Prominence メソッド移管性
中面 2 Hot News Vol.13 2012.07 2012.09 可能性 拡がる Nexera コアシェル リンク 3.6μmのコアシェルを用いれば アセトニトリル 水系で背圧10MPa 程度でご使用頂けます 1.7μm 2.6μm 3.6μm UFLC Prominence メソッド移管性が高い 下記の結果より 分離係数 α が同等で 粒子 サイズ間で 1 Aeris Peptide XB-C18
More informationa b Chroma Graphein Chromatography
a b Chroma Graphein Chromatography (Stationary Phase) (Mobile Phase) CHROMATOGRAPHY GAS SFC LIQUID GSC GLC Column Planar NP RP IEC SEC TLC Paper Normal Phase Reverse Phase GPC GFC Thin Layer Chromato.
More informationuntitled
Kw 1-12 1-13 Kw van t Hoff 0 0 0 H S d ln K H ln K = + = RT R d(1/ T ) R ln KW 1/T H 0 /R H 0 = 51.0 kj mol -1 HCl H + + Cl - H2O H + + OH - [] [H + ] [OH - ]=10-14 M 2 25 OH - x OH - [OH - ]=x [H + ]
More informationFigure 1 Detection process of ELSD. All droplets enter the evaporation process Figure 2 Only small droplets enter the evaporation process Nebulization
Technical Review How to Use Evaporative Light Scattering Detector Effectively Hidetoshi Terada, Yoshihiro Hayakawa and Hirohisa Mikami Analytical & Measuring Instruments Division, Shimadzu Corporation
More informationGPC/SEC
GPC/SEC Agilent GPC/SEC...3... 5...5...7...9...11...12... 13...13...14... 15...15...16... 18...18...19 /... 21...21... 23 GPC/SEC...24 Q Q Q Q Q 35 GPC/SEC 24 365 GPC/SEC GPC/SEC GPC 2 80 % 2006 - Polyplasdone
More informationuntitled
Frank David Research Institute for Chromatography President Kennedy Park B- Kortrijk, Belgium Pat Sandra University of Gent Krijgslaan 281 S4, B-9000 Gent Belgium Allen K. Vickers Agilent Technologies,
More informationJAJP.qxp
Agilent 1200 LC Our measure is your success. products applications software services - 4 90,000-20 HPLC - UV-Vis ELSD LC/MS - - Agilent 1200 LC (RRLC) 1 RRLC Agilent 1200 LC 2 2 ZORBAX HT 1.8 µm Poroshell
More information平成26年度 化学物質分析法開発報告書
2,2-2,2 -Iminodiethanol Diethanol amine CAS 111-42-2 C 4 H 11 NO 2 105.1356-105.0790-28 C 1) 1.0881 g/cm 3 1)
More informationGroup A (2,5-Dimethoxyphenyl type) 25D-NBMe (1) 25B-NBMe (2) 25I-NBMe (3) 25C-NBF () 25B-NBF (5) Group B (Benzofuran-2-yl type) Group C (-Alkoxy-3,5-d
3 * * * * * Analytical data of designer drugs of synthetic phenethylamines Ryosuke SASAKI*, Miho KAT*, Tsuyoshi MATSUMT*, Akira UDAGAWA* and Ryuichi MATSUZAKI* *Tokyo Customs Laboratory 2-7-11, Aomi, Koto-ku,
More informationMicrosoft PowerPoint - HILICandSAC
極性化合物の分離に! ILIC,C8 C8-SC の 基礎と上手な使い方! 一般の C8 では分離が難しい極性化合物に適した ILIC とlanol ctivity Controlled C8 の活用法について説明いたしますいたします 7/8/ :-: - 会場於 : アパホテル & リゾート東京ベイ幕張ホール クロマニックテクノロジーズ Chromai Technologies Inc. TEL:
More informationCHEMOTHERAPY APR Fig. 1 Chemical structure of cefotetan (CTT, YM09330)
CHEMOTHERAPY APR. 1982 Fig. 1 Chemical structure of cefotetan (CTT, YM09330) VOL.30 S-1 CHEMOTHERAPY Fig. 2 Comparison of standard curves of CTT on various test organisms by cylinder plate method Column
More informationAdenosine Triphosphate Adenosine Monophosphate min Fig.2 Chromatograms of Nucleotides min Peak
Adenosine Triphosphate Adenosine Monophosphate 0.0 1.0 2.0 3.0 4.0 5.0 6.0 min Fig.2 Chromatograms of Nucleotides 0.0 1.0 2.0 3.0 4.0 5.0 6.0 min Peak Asymmetry Peak 1 Peak 2 1.39 1.14 5.10 1.49 Instrument
More informationEffect of Roasting on the Formation of Chlorogenic Acid Lactones in Coffee
Effect of Roasting on the Formation of Chlorogenic Acid Lactones in Coffee 著者 : ADRIANA FARAH, TMAS DE PAULIS, LUIZ C. TRUG,PETER R. MARTIN 雑誌 : J. Agric. Food Chem. 2005, 53, 1505-1513 紹介者 : 北河広大 2013.1.18(Fri)
More informationPreparative chromatography
1980 HPLC column System for production/purification Packing material Flow reaction Contract purification CONTENTS 2 3 4 00 8 01 9 BioStream YMC Pilot 12 02 HPLC13 HPLC LC-Forte/R14 HPLC K-Prep15 18 HPLC
More information東京都健康安全研究センター研究年報
Ann. Rep. Tokyo Metr. Inst. P.H., 55, 2004 化粧品に配合される新規頭髪用染料の分析法 Analysis of ew Hair Colorants of Cosmetics ahomi UKI Yoshiaki AKAMURA Ken'ichiro MORI Kiyosi TERASHIMA Toshiro YOKOYAMA and Kouichi IT A
More informationlow_ JAJP.qxd
LC/MS Chad Borges, Matthew Slawson, James Taccogno, and Dennis Crouch Center for uman Toxicology University of Utah Salt Lake City, UT USA John M. ughes Agilent Technologies, Inc. Pleasanton, CA USA (oa-tof)
More information平成26年度 化学物質分析法開発報告書
2,2-2,2 -Iminodiethanol Diethanol amine CAS 111-42-2 C 4 H 11 NO 2 105.1356-105.0790-28 C 1) 1.0881 g/cm 3 1)
More informationLC/TOF-MS MS ( )
LC/TOF-MS MS () (TOF-MS) MS) LC/MS 1. 2. Agilent 1100 LC/TOF-MS MS ~0.25ppm / C ambient Compound Exact mass Positive Negative Purine 121.050873 TFA 112.985587 Hexakis(1H, 1H, 3H 922.009798 966.000725 1)
More information平成26年度 化学物質分析法開発報告書
N,N- N,N-Dimethylacetamide Acethyldimethylamine CAS 127-19-5 C 4 H 9 NO 87.12 ~ 87.14 87.68413 163-165 C 1) - 18.59 C 2) 1 mg/l 25 C 3) 3.3 hpa 2 C 4) log P ow -.77 2).9429 2/4 C 1) 3.1 4) 1.31E - 8 atm-m
More informationJAJP.qxd
Agilent 7500 ICP-MS 2 (ORS) 2 G3275A G3151A (7500a) G3152A (7500i) 4 G3153A (7500s) ORS G3276A G3151B (7500a) 4 G3153B (7500s) ORS G3277A G3155A (7500c) ORS 5 G3278A G3155B (7500c) ORS 5 G3279A G3271A
More information大和会だよりvol71
vol. 71 since 1999 http://www.yamatokai.or.jp Column http://www.yamatokai.or.jp/public/lecture/ KH090408 LDL 110 LDL 100 File.2 TEL. 042-562-1411 TEL. 042-566-3111 TEL. 042-566-6631 TEL. 042-562-5738
More informationa a b a b c d e R c d e A a b e a b a b c d a b c d e f a M a b f d a M b a b a M b a M b M M M R M a M b M c a M a R b A a b b a CF a b c a b a M b a b M a M b c a A b a b M b a A b a M b C a M C a M
More information(DHA) 1 4 6 µg/ml 2,3 4 DHA AOAC 967.22 DHA C UVDHA 22 nm ph 244 265 nm 5 AOAC 994.11 UV UV HPLC Milli Q (Millipore Elix 1 ) Lab-Scan ( ) Fluka () o-
Agilent Syed Salman Lateef Agilent Technologies, Inc. Bangalore, India 8 6 4 2 1.191 1.678 12.46 2.5 5 7.5 1 12.5 ( C) ( ) Agilent Poroshell EC-C18 Agilent 126 Infinity LC (LOD).2 µg/ml 3 9 % Agilent 129
More informationmastro_nakamen三校.ai
Hydrocortisone Sodium Phosphate 3.5 1.0 0.5 1 μg/ml 3.0 2.5 25 ng/ml 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 min 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 min Fig.1 Chromatograms of Hydrocortisone
More information[PDF] マニュアル AKTAexplorer UNICORN ver. 4.0
A m e r s h a m P h a r m a c i a B i o t e c h ÄKTAdesign ÄKTAexplorer 71-1190-34 Ä Ä Ä ä ÄKTAexplorer ÄKTAexplorer 10S Ä Ä µ µ Ä ÄKTAexplorer 10S M-925 ÄKTAexplorer 100 0, 6 3 µ µ µ ml µ P-950 0 5
More information<4D F736F F D C6E30385F A B B83932E444F43>
1,2,4-1,2,4-Trimethylbenzene Pseudocumene 1,3,5-1,3,5-Trimethylbenzene Mesitylene CH 3 CH 3 CH 3 CH 3 CH 3 CH 3 1,2,4-trimethylbenzene 1,3,5-trimethylbenzene CAS 95-63-6 CAS 108-67-8 C 9 H 12 C 9 H 12
More information創薬と結晶構造解析-3.key
( 460-377 3 2 3 ? Neuraminidase and Tamiflu http://www.roche.com/research_and_development/innovation_and_technologies.htm 2? ( ) Ligand-based drug design Ligand-based drug design (Pharmacophore-based drug
More informationuntitled
2017 5 26 350 Restek time time time increasing time μ = = k = t r t o t o = t r ' t o van Deemter Equation H A B H = height equivalent theoretical plate (HETP) A = Eddy diffusion term B = Molecular diffusion
More information10 117 5 1 121841 4 15 12 7 27 12 6 31856 8 21 1983-2 - 321899 12 21656 2 45 9 2 131816 4 91812 11 20 1887 461971 11 3 2 161703 11 13 98 3 16201700-3 - 2 35 6 7 8 9 12 13 12 481973 12 2 571982 161703 11
More information0.45m1.00m 1.00m 1.00m 0.33m 0.33m 0.33m 0.45m 1.00m 2
24 11 10 24 12 10 30 1 0.45m1.00m 1.00m 1.00m 0.33m 0.33m 0.33m 0.45m 1.00m 2 23% 29% 71% 67% 6% 4% n=1525 n=1137 6% +6% -4% -2% 21% 30% 5% 35% 6% 6% 11% 40% 37% 36 172 166 371 213 226 177 54 382 704 216
More informationC18①s
ニーズに合わせて 種類のラインナップ! スタンダード C8 適度な炭素量で回収率を重視 高容量 C8 より強い保持力を発揮 ハイフロー C8 粘性サンプル向け ラージポア C8 高分子向け 充てん剤の仕様 スタンダード C8 充てん剤の仕様 充てん剤粒子径孔径炭素量 スタンダード C8 0µm 0Å % 高容量 C8 0µm 0Å 7% ハイフロー C8 00µm 0Å 8% ラージポア C8 0µm
More informationChart 1.Method for Preparation of 1.25% Indomethacin Inhalation Solution (ph 7.4)
JPn.J.Hosp.Pharm. Stability of Indomethacin in Aqueous Solution(1): Kinetic Studies and Effect of Solvents on the Hydrolysis of Indomethacin KAORU CHIBA*,MASANAO TAKAHASHI,NOBUMASA HAYASE, SHIGETAKA AKUTSU,SHUN-ICHI
More informationTitle 数種の中国産甘草サポニン成分の化学的研究 Author(s) 堀, 一之 Citation Issue Date Text Version ETD URL https://doi.org/10.11501/3070540 DOI 10.11501/3070540 rights 0 0 II C 0 COOR COOK OH HOH COOR 0 OH HOO H H3 16
More information1 WSV SIR m/z Analyte RT (Min) SIR m/z Cone voltage (V) Ascorbic Acid (C).91 177 2 Thiamine (B1) 1.1 265 5 Nicotinic Acid (B3) 1.27 124 15 Pyridoxal (
ACQUITY UPLC H-Class ACQUITY QDa Mark E. Benvenuti, Dimple Shah, and Jennifer A. Burgess Waters Corporation, Milford, MA, USA MS ACQUITY QDa UPLC HPLC UV ACQUITY QDa LC EC 1925/26 CFR 21 HPLC 1 LC-MS ACQUITY
More informationOxidative Dimerization of Tocopherols in Saturated and Unsaturated Triglycerides. III Formation of 5-(ƒÂ-Tocopheroxy)-ƒÂ-5-tocopherol and 5-(ƒÂ-Tocoph
Oxidative Dimerization of Tocopherols in Saturated and Unsaturated Triglycerides. III Formation of 5-(ƒÂ-Tocopheroxy)-ƒÂ-5-tocopherol and 5-(ƒÂ-Tocopherol-5-yl)-ƒÂ-tocopherol from ƒâ-tocopherol Tsuyoshi
More information2 Agilent OpenLAB CDS OpenLAB CDS OpenLAB CDS OpenLAB IT 2
Agilent OpenLAB (CDS) 2 Agilent OpenLAB CDS OpenLAB CDS OpenLAB CDS OpenLAB IT 2 OpenLAB CDS 30 OpenLAB OpenLAB Agilent Professional Services (Site Preparation General Consulting Services) OpenLAB OpenLAB
More informationMicrosoft PowerPoint - MonoTowerカタログ_ 最終.ppt [互換モード]
次世代型シリカモノリスカートリッジカラム MonoTower TM C18 次世代型シリカモノリスカートリッジカラム MonoTower TM C18 MonoTower TM C18 モノリスカートリッジを連結することで高い理論段数を低圧力で実現 粒子充填型 ODS カラム (3 μm, 250 3.0 mm I.D.) 15.5 MPa 分離不充分 (500 3.0 mm I.D.) 14.5
More informationUPC 2 Baiba Cabovska, Michael D. Jones, and Andrew Aubin Waters Corporation, Milford, MA, USA UPC 2 ACQUITY UPC 2TM ACQUITY SQD Empower 3 UPC GC
UPC 2 Baiba Cabovska, Michael D. Jones, and Andrew Aubin Waters Corporation, Milford, MA, USA UPC 2 ACQUITY UPC 2TM ACQUITY SQD Empower 3 UPC 2 1-3 GC LC GC UltraPerformance Convergence Chromatography
More informationESL ()-methyl 3-{4-[2-hydroxy-3-(isopropylamino)pro poxy]phenyl} propanoate monohydrochloride H 3 C O O JAN( ) JAN( )esmolol hydrochloride r-inn( )esm
1 186 186 (1) - 192 (2) (ISAintrinsic sympathomimetic activity) 199 (3) ( MSAmembrane stabilizing activity) 2 (4) 21 (5) 212 (6) 216 (7) 219 (8) 224 (9) (ASL-8123) - 229 (1) d-esl l-esl - 231 2 235 235
More informationJAJP.indd
Agilent VistaFlux 1 C- Hui Liu, Weige Qin, Hardik Shah, Bhavapriya Vaitheesvaran, Vladimir Yong, and Justin R. Cross Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering
More informationJAJP
Agilent 7500ce ORS ICP-MS Glenn Woods Agilent Technologies Ltd. 5500 Lakeside, Cheadle Royal Business Park Stockport UK Agilent 7500ce ICP-MS 5 7500ce (ORS) 1 ORS 7500ce ORS ICP-MS ( ) 7500 ICP-MS (27.12
More information1 No.236 HP TAXUS
Drug Information News 1 No.236 HP http://www1.mhlw.go.jp/kinkyu/iyaku_j/iyaku_j/anzenseijyouhou/236.pdf TAXUS 186 12 1 1 3050 L 30L 7L 1 (1 ) ( ) 510mm 2 1 2 ph 10 2030 瘙 瘙 瘙 瘙 瘙 瘙 瘙 瘙
More information島津ジーエルシー総合カタログ2017【HPLCカラム】
56 Shimadzu GLC Ltd.H Luna R 社独自の技術をもとに 優れた ph 安定性と再現性を持つ逆相系カラムです ph1.5-9.0( ) の ph 領域において 酸性 塩基性および両性化合物の分析が可能です ph1.5-9.0( ) の領域において 1,000 時間以上安定してお使いいただけます 多種の粒子径やカラムサイズ 固定相を取り揃えております ガードカラムを除くすべてのカラムに基材品質保証書
More informationPowerPoint プレゼンテーション
今までのカラムと何が違う? コアシェルカラムの基礎の基礎 クロマニックテクノロジーズ塚本友康長江徳和 Email: info@chromanik.co.jp http://chromanik.co.jp 市販されているコアシェルカラム SunShell( クロマニックテクノロジーズ ) : C18, PFP, C8, RP-Aqua, C4-30, C8-30 Halo(AMT) Capcell Core(
More informationスライド 1
Zirconia Based Ion Exchange Phase HPLC Column 高耐熱性, 高耐久性, 高分離能 イオン交換クロマトグラフィーカラム 株式会社クロマニックテクノロジーズ / www.chromanik.co.jp ZirChrom Zirconia Based High-Stability Column 2 µm 多孔性ジルコニアジルコニア (ZrO 2 ) は, 結晶あるいは非晶質で存
More informationまえがき
JAAS0012006 1 -------------------------------------------------------------------------------------------------------- 1 2 --------------------------------------------------------------------------------------------------------
More informationLiner natomy ライナーの手引き Innovative Chromatography Products
Liner natomy ライナーの手引き Innovative Chromatography Products www.restek.jp はじめに ( ) & ( ) Gerstel PTV PTV PTV(PROGRAMMABLE TEMPERATURE VAPORIZATION) LVI(LARGE VOLUME INJECTIONS) PTV LVI PTV LVI ( PETN 100
More information島津ジーエルシー総合カタログ2017【HPLCカラム】
64 Shimadzu GLC Ltd.PLCカラム0 Synergi TM 基材として粒子径 4µm 細孔径 80A のシリカ粒子を使用しています 粒子径 3µm のカラムに近いカラム効率が得られます 粒子径 5µm のカラムと同様のカラム圧で分析可能です 基材として高純度シリカ (99.99%) を用いることで キレートの原因となる金属不純物が減少し 中性移動相条件下でも残存シラノール基の活性を抑えることが可能です
More information248 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /-, No./,,.2,/. (,**0) 12 * * * Microencapsulation of Glutamine with Zein by a Solvent Evaporation Metho
248 Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /-, No./,,.2,/. (,**0) 12 * * * Microencapsulation of Glutamine with Zein by a Solvent Evaporation Method in Reverse Multiple Emulsion Masato Tanaka*, Yoshinari
More information研修コーナー
l l l l l l l l l l l α α β l µ l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l l
More informationgc-guide
...1...3 (Direct Injection)...5 OCI...7 PTV (...9 FID...11 ECD...13 AOC-20i/s...15...17...19 10 1 10 1 2µL 1µL 1mL 0.10.2mL He (He) 25cm/sec40cm/sec 30mL/min 1:501:100 Table Ex. Rtx-1, 515m :Ex. 100cm/sec
More informationAgilent BioHPLC HPLC/UHPLC /
Agilent BioHPLC HPLC/UHPLC / HPLC/UHPLC ( Å Å ) BioHPLC MPa.. µm UHPLC Poroshell ( ) Agilent AdvanceBio RP-mAb : AdvanceBio RP-mAb Poroshell mab Agilent AdvanceBio :.7 µm C AdvanceBio Agilent Poroshell
More information1. 52
51 1. 52 5 2. 1 2 54 4 55 5 1 56 2 57 . 1 1 58 2 1 59 2 4 60 61 62 6 64 4. 65 66 67 5 1 2 4 68 1 69 2 70 1 2 71 72 1 2 7 1 2 74 75 1 76 2 77 1 2 78 4 79 5 80 6. 1 81 2 82 8 84 85 86 87 7. 88 89 8. column
More information1 2 2 36 8 1212 15 16 20 22 24 26 28 8 14 21 1 31 32 32 3335 37 39 43 45 48 49 5051 54 56 58 6264 6669 43 50 58 2 73 74 7779 8183 85 88 91 93 9698 100 102103 74 85 93 106 106 108 110 112 3 115 116 116
More informationuntitled
CH 2 H H H CH 2 n-1 H CH 2 n H Potato α-glucan phosphorylase H n soluble starch P i n-1 H P() 2 glucose-1-phosphate Pi H CBPase H glucose P i glucose-1-phospate cellobiose H cellooligosaccharide n+1 CDPase
More information平成23年度電気設備技術基準関係規格等調査役務請負報告書
1 V 3 L 150 100 V 6 I 10 1 V 3 L 2 1 I1 2 3 0 3 R R V R 3 10 X V X 3 10 R X 2 2 2 2 2 3 2 I 1 2 2 3 2 168 171-1
More information外因性内分泌攪乱化学物質調査暫定マニュアル(水質、底質、水生生物)
N- 1) 2) 1) GC/MS HPLC GC/MS 2) 0.01~0.05µg/l 0.5~50µg/kg GC/MS SIM GC/MS SIM GC/MS SIM a) b) -d 10 -d 10 -d 12 -d 12 c) d) 600 C 4 e) 1 99.999% f) a) b) - IX-1 - c) (ODS) 200-1,000mg 5ml 5ml 5ml d) e)
More informationパワープロジェクター WUX10 使用説明書
2 1 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 1 2 3 26 27 28 29 30 1 2 31 32 33 34 35 36 37 38 39 1 2 3 4 40 5 41 42 43 44 45 1 2 3 46 1 2 1 2 3 3 1 2 3 4 47 48 1 2 3 49 1 2 3 50 1
More informationMAbPac RPカラム
CHROMATOGRAPHY CONSUMABLES MAbPac RP Product Specifications Thermo Scientific MAbPac RP LC HCFc Fab scfc F ab LC/ UV LC/MS ph DTT ph 14 11 ºC mab QC mab mab Fc Fab scfc F ab mab QC LC/UV mab MAbPac RP
More information平成25年度 化学物質分析法開発報告書
2,4-2,4-Dimethylaniline 2,4-2,4-Xylidine CH 3 CH 3 CAS 95-68-1 C 8 H 11 N 121.18 121.0892-14.3 C 2) 214 C 2) 0.9723 g/cm 3 2) 0.133 mmhg (25 C) 1) 1390 mg/l (25 C) 1) 3.710 3 mg/l 25 C WSKOWWIN 5) 6.0710
More informationヒト血漿中オキシステロールの高感度分析法
High sensitive determination of oxysterols in human plasma using gas chromatography-mass spectrometry (GC-MS) Saori Nakagawa and Susumu Yamato Oxysterols, cholesterol oxidation products, have been important
More information逆相 HPLC 分析におけるメソッド開発 1. 逆相 HPLC 分析におけるメソッド開発 1.1 カラム 1.2 移動相 1.3 試料 2. トラブルシューティング 1
これでレベルアップ 逆相 HPLC 分析におけるメソッド開発に役 つノウハウとトラブルシューティングの解説 般財団法 化学物質評価研究機構クロマト技術部 0 逆相 HPLC 分析におけるメソッド開発 1. 逆相 HPLC 分析におけるメソッド開発 1.1 カラム 1.2 移動相 1.3 試料 2. トラブルシューティング 1 メソッド開発のフロー例 情報収集既存法 類似情報 献 メソッド開発の 標の設定
More information