外因性内分泌攪乱化学物質調査暫定マニュアル（水質、底質、水生生物）
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- はすな はぎにわ
- 5 years ago
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4 (PCB) 1 ng/l (µg/kg, wet) (µg/kg) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) MS GC/MS-SIM 1M KOH GC/MS-SIM Wellington Laboratories BP-WD Wellington Laboratories BP-MS KC-300 KC-400 KC-500, KC mg/L 400mg/L I-1
5 Wellington Laboratories BP-WD PCB PCB Congener IUPAC No. 2- Chlorobiphenyl 1 4-Chlorobiphenyl 3 2,6-Dichlorobiphenyl 10 4,4'-Dichlorobiphenyl 15 2,2',6-Trichlorobiphenyl 19 3,4,4'- Trichlorobiphenyl 37 2,2',6,6'-Tetrachlorobiphenyl 54 3,3',4,4'- Tetrachlorobiphenyl 77 2,2',4,6,6'-Pentachlorobiphenyl 104 3,3',4,4',5- Pentachlorobiphenyl 126 2,2',4,4',6,6'-Hexachlorobiphenyl 155 3,3',4,4',5,5'- Hexachlorobiphenyl 169 2,2',3,4',5,6,6'-Heptachlorobiphenyl 188 2,2',3,4,4',5,5'- Heptachlorobiphenyl 189 2,2',3,3',4,4',5,5'-Octachlorobiphenyl 202 2,3,3',4,4',5,5',6-Octachlorobipheny 205 2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl 206 2,2',3,3',4,5,5',6,6'- Nonachlorobiphenyl 208 2,2',3,3',4,4',5,5',6,6'-Decachlorobiphenyl 209 Wellington Laboratories BP-MS PCB PCB Congener IUPAC No. Monochlorobiphenyl 1, 3 Dichlorobiphenyl 4, 8, 10, 15 Trichlorobiphenyl 18, 19, 22, 28, 33, 37 Tetrachlorobiphenyl 44, 49, 52, 54, 70, 74,77, 81 Pentachlorobiphenyl 87, 95, 99, 101, 104, 105, 110, 114, 118, 119, 123, 126 Hexachlorobiphenyl 128, 138, 149, 151, 153, 155, 156, 157, 158, 167, 168, 169 Heptachlorobiphenyl 170, 171, 177, 178, 180, 183, 187, 188, 189, 191 Octachlorobiphenyl 194, 199, 201, 202, 205 Nonachlorobiphenyl 206, 208 Decachlorobiphenyl 209 Wellington Laboratories MBP-CG I-2
6 Wellington Laboratories MBP-CG 13 C PCB PCB Congener IUPAC No. 4-Chloro[13C12]biphenyl 3 4,4'- Dichloro[13C12]biphenyl 15 2,4',5- Trichloro[13C12]biphenyl 31 2,2',5,5'- Tetrachloro[13C12]biphenyl 52 2,3',4,4',5- Pentachloro[13C12]biphenyl 118 2,2',4,4',5,5'- Hexachloro[13C12]biphenyl 153 2,2',3,4,4',5,5'- Heptachloro[13C12]biphenyl 180 2,2',3,3',4,4',5,5'- Octachloro[13C12]biphenyl 194 2,2',3,3',4,4',5,5',6- Nonachloro[13C12]biphenyl 206 2,2',3,3',4,4',5,5',6,6'- Decachloro[13C12]biphenyl 209 d m ODS Sep-Pak Plus Silica Cartridge (690 mg) ( aters ) 10ml % 1M KOH 1M 5% C g 300ml 5ml I-3
7 30cm 10mm 5g 2cm 40ml GC/MS MS MS 1L 2L 10ml 30g 10ng 100ng 100ml 10 50ml 200ml 200ml 30 1ml 20g 200ml 10ng 100ng 1M KOH 50ml 80 50ml (GF/A) 20ml 30ml I-4
8 300ml 50ml 10 20ml 300ml 50ml 300ml 50ml 300ml 50ml 200ml 200ml 30 3ml 10ml 10ml 1ml 100ng 50ml 30 3ml 1ml 100ng 10mg I-5
9 100ml 100 g/ml 20 HT m 5% DB-5MS Ultra2 SGE cm/sec He 70 I-6
10 4-Chloro[13C12]biphenyl 4,4'- Dichloro[13C12]biphenyl 2,4',5- Trichloro[13C12]biphenyl 2,2',5,5'- Tetrachloro[13C12]biphenyl 2,3',4,4',5- Pentachloro[13C12]biphenyl 2,2',4,4',5,5'- Hexachloro[13C12]biphenyl 2,2',3,4,4',5,5'- Heptachloro[13C12]biphenyl 2,2',3,3',4,4',5,5'- Octachloro[13C12]biphenyl 2,2',3,3',4,4',5,5',6- Nonachloro[13C12]biphenyl 2,2',3,3',4,4',5,5',6,6'- Decachloro[13C12]biphenyl d % 70 (1.9min)--8 /min--300 (15min) I-7
11 4-Chloro[13C12]biphenyl 4,4'- Dichloro[13C12]biphenyl 2,4',5- Trichloro[13C12]biphenyl 2,2',5,5'- Tetrachloro[13C12]biphenyl 2,3',4,4',5- Pentachloro[13C12]biphenyl 2,2',4,4',5,5'- Hexachloro[13C12]biphenyl 2,2',3,4,4',5,5'- Heptachloro[13C12]biphenyl 2,2',3,3',4,4',5,5'- Octachloro[13C12]biphenyl 2,2',3,3',4,4',5,5',6- Nonachloro[13C12]biphenyl 2,2',3,3',4,4',5,5',6,6'- Decachloro[13C12]biphenyl d GC/MS GC/MS I-8
12 p,p'-ddt 1mg/L 1 L GC/MS DDT DDD DDE 20% DDT 20% cm SIM (RF) RF RF 15% RF 15% RF 15% RF RF=(As Cis)/(Ais Cs) As Ais Cis (ng) Cs (ng) KC-300 KC-600 (Cs ng) (ng) = (ng) mg/L KC-300 KC BZ#1 BZ#1 (ng) = 100ng = ng GC/MS SIM RF 8 RF RF 15% GC/MS RF I-9
13 PCB PCB window (5% phenyl methyl siloxane) PCB IUPAC #1, #3, #10, #15, #19, #37, #54, #77, #104, #126, #155, #169, #188, #189, #202, #205, #206, #208, #209 GC 5% phenyl methyl siloxane 4 4 2,2,6,6 - (IUPAC : #54) PCB 3,3,4,4 - (IUPAC : #77) GC PCB PCB 5 20% PCB SGE HT8 PCB PCB PCB (M-70) 5 20% PCB PCB PCB RF PCB Wellington Laboratories BP-MS BP-MS RF KC-300 KC-600 PCB PCB KC-300 KC-600 I-10
14 RF (ng) (ng)=(as Cis)/(Ais RF) As Ais Cis (ng) 10 50% 120% 80% 120% (CRM) (x) (s) (DL) DL = x s I-11
15 (s) (DL) DL = s MS PCB ODS 1M KOH 50ml 1M KOH 100ml I-12
16 HPLC µbondapak NH 2, 9mm i.d. 30cm, Waters (LC-NH 2 ) PCB 5% g MS HPLC PCB GC PCB KC300 KC600 M+70 PCB 5 10 JIS Z PCB CRM NIST SRM 1939 Wellington Laboratories CARP-1 20g WindowsPCB19 100ng -d 10 I-13
17 20g 100ng IUPAC PCB , ,2', ,4' ,2',6,6' ,2',4,6,6' ,4,4' ,2',4,4',6,6' ,3',4,4' ,2',3,4',5,6,6' ,3',4,4', ,2',3,3',5,5',6, ,3',4,4',5,5' ,3,3',4,4',5,5' ,2',3,3',4,5,5',6,6' ,3,3',4,4',5,5', ,2,',3,3',4,4',5,5, ,2',3,3',4,4',5,5,6,6' g 100ng IUPAC PCB , ,2', ,4' ,2',6,6' ,2',4,6,6' ,4,4' ,2',4,4',6,6' ,3',4,4' ,2',3,4',5,6,6' ,3',4,4', ,2',3,3',5,5',6, ,3',4,4',5,5' ,3,3',4,4',5,5' ,2',3,3',4,5,5',6,6' ,3,3',4,4',5,5', ,2,',3,3',4,4',5,5, ,2',3,3',4,4',5,5,6,6' I-14
18 1997 4,4' JIS Z WHO 1994 Analytical Chemistry of PCBs, M. D. Erickson, Butterworth Publishers, Polychlorinated biphenyls in the environment, V. Lang, J. Chromatogr., 595, 1-43, Mass Spectrometric Determination of Polychlorinated Biphenyls as Isomer Groups, J. E. Gebhart, T. L. Hayes, A. L. Alford-Stevens and W. L. Budde, Anal. Chem., 57, , Determination of Byproduct Polychlorobiphenyls in Commercial Products and Waters by High-Resolution Gas Chromatography/Electron Impact Mass Spectrometry, M. D. Erickson, J. S. Stanley, J. K. Turman, J. E. Going, D. P. Redford and D. T. Heggem, Environ. Sci. Technol, 22, 71-76, Comparison of methods for the gas-chromatographic determination of PCB congeners and chlorinated pesticides in marine reference materials, M. M. Schantz, R. M. Parris, J. Kurz, K. Ballschmiter and S. A. Wise, Fresenius J. Anal. Chem., 346, , I-15
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26 p,p -DDT p,p -DDE p,p -DDD trans- cis- trans- cis- (PBB) (BaP) 25ng/L 5µg/kg GC/MS-SIM GC/MS-SIM GC/MS-SIM GC/MS-SIM (2-, 3-, 4- ) (4,4'- ) p,p'-ddt- 13 C 12 HCB- 13 C 6 BaP-d 12 -d10 -d 10 p- -d II-1
27 m ODS 96% II / % C g 300ml 5ml (Atlas Powder Co. )100g 2L 1L 30 1L % 25g 75g 30 Sep-Pak Plus Silica Cartridge (690 mg) (Waters ) 10ml 60 80
28 30ml (KD) 30cm 15mm 10g 2cm 100ml 30cm 10mm 5g 2cm 40ml 30cm 10mm 2.5% 10g 30% 2cm 30% GC/MS 1L 2L 30g 10ng 100ng 50ml 10 KD 5ml 1ml 20g 100ml 10ng 100ng 50ml rpm 10 5 II-3
29 500ml 1 50ml 5 KD 5ml BaP 40g 20ng 200ng 40ml 80ml 3000rpm ml 200ml KD 50ml 50ml 25ml 25ml 100ml 50ml 50ml 5ml 5 500ml 1L 50ml 300ml 100ml KD 5ml 25ml 50ml 10ml 50ml KD 5ml 2% II-4
30 ml KD 100ng 1000ng 1ml (Fr 1) 4 100ml(Fr 2) ml(Fr 3) 5ml Fr g 10g 10mm 300mm KD ml 100ng 1000ng 1ml (Fr 1) 4 100ml(Fr 2) ml(Fr 3) 5ml KD ml 100ng 1000ng 1ml 5ml KD ml 1ml 10mg 100mg/L p,p'-ddt- 13 C 12 HCB- 13 C 6 BaP-d 12 -d 10 -d 10 p- -d 14 II-5
31 20 GC/MS 30m 0.25mmi.d m 0.25mmi.d. 40cm cm % 50 (1 ) L m 0.25mmi.d m 15m 50 (1 ) L eV EI SIM 1 2 II-6
32 (PTRI, Programmed Temperature Retention Index) PTRI No CAS RN * p,p -DDT p,p -DDE p,p -DDD trans cis trans cis (HCB) * PTRI n- 5% II-7
33 No p,p'-ddt- 13 C HCB- 13 C d d d p- -d GC/MS GC/MS p,p'-ddt (DFTPP) 1mg/L 1 L GC/MS DDT DDD DDE 20% DDT 20% cm MS DFTPP 3 DFTPP SIM II-8
34 (RF) (RF) RF RF 15% RF 15% RF 15% RF RF=(As Cis)/(Ais Cs) As Ais Cis (ng) Cs (ng) 1 GC/MS SIM RF p,p'-ddt- 13 C 12 DDD DDE 20% 20% 8 RF RF 15% GC/MS RF 5 20% II-9
35 RF RF (ng) (ng)=(as Cis)/(Ais RF) As Ais Cis (ng) 10 80% 120% 80% 120% NIST EU BCR CRM (CRM) CRM II-10
36 (x) (s) (DL) DL = x s (s) (DL) DL = s (5ml) 2 g 5ml 20ml GC/MS p,p'-dde p,p'-ddt p,p'-dde 4% 100ml p,p'-ddt 15% 150ml BaP ODS II-11
37 15 30 GC/MS 30% Fr.3 Fr.3 5% 10ml 5% (5g) : 10ml Hexane 5% Acetone-Hexane 30% Acetone-Hexane Fr.1-1 Fr.1-2 Fr.1-3 Total Fr.2-1 Fr.2-2 Fr.2-3 Total Fr.3-1 Fr.3-2 Fr.3-3 Total BaP α-hch β-hch γ-hch δ-hch (Fr 1) II-12
38 15 150ml 209 RF %RSD 15% DDT HCB 13 C BaP 80% 120% 5 10 JIS Z CRM ( NIST SRM 1588) (EU BCR CRM 187, CRM 188) (EU BCR CRM 430) CRM 20g II-13
39 Compound µ µ Hexachlorobenzene * alpha-hch beta-hch gamma-hch delta-hch Heptachlor Aldrin Heptachlor epoxide Oxychlordene trans-chlordane cis-chlordane Endosulfan I trans-nonachlor ,4'-DDE Dieldrin Endrin ,4'-DDD * cis-nonachlor Endosulfan sulfate ,4'-DDT * Endrin ketone Methoxychlor Benzo(a)pyrene * Standard Methods 19th ed. American Public Health Association, EPA Method 8270B, US EPA, Official Methods of Analysis of The Association of Official Analytical Chemists 15th ed. Vol. 1, Association of Official Analytical Chemists, Inc., II-14
40 4,4' JIS Z J.R. Chapman, Wiley 1995 WHO II-15
41 -16
42 4-t- 4-n- 4-n- 4-4-t- 4-n- 100ng/L 50ng/g 10ng/L 5ng/g SS SS GC/MS-SIM GC/MS-SIM GC/MS-SIM GC/MS-SIM -d 8 -d III-1
43 2cm 20cm 5 15g 2cm GC/MSGC MS L 1M ph 3 30g SS JIS-K0102 SS SS 5mL 50mL mL 1M ph3.5 L 5mL 10mL 0.3mL mL III-2
44 20g 5ml 100ml 50ml rpm ml L 50ml ml 20g 100ml rpm ml 3 5ml 30ml 300ml 30ml 5 500ml L 1mL 50ml ml 0.5mL 100ml 100ml 1ml -d 8 -d 10 1µg/ml 1ml 1ml -d 8 -d 10 g/ml ml 1mL -d 8 -d 10 g/ml ml III-3
45 3g 20g g 100mg 1000mg/L -d 8 -d GC/MS GC 30m 0.25mmI.D. d f =0.25 m L He 40cm 280 MS EI 70eV 250 III-4
46 SIM PTRI= Programmed Temperature Retention Index CAS Registry Number PTRI 4-t n n t n d 8 < d PTRI n- L GC L GC 15 GC/MS 20 III-5
47 µg/ml ng ml GC L ml µg/g ng ml GC L g 100 L mL SS Sep-Pack SP- 2 Oasis TM HLB SDB-RPS 15 30ml III-6
48 6 (1996) (1998) (1998). III-7
49 2,4-10ng/L 5ng/g SS SS GC/MS-SIM GC/MS-SIM GC/MS-SIM GC/MS-SIM -d 10 N,O-bis(trimethylsilyl)trifluoroacetamide cm 20cm 5 III-8
50 15g 2cm GC/MSGC MS L 1M ph 3 30g -d 16 SS JIS-K0102 SS SS 5mL 50mL mL 1M ph3.5 L 9mL 10mL 0.5mL III-9
51 20g 5ml µg100ml 50ml rpm ml L 50ml ml 20g µg 100ml rpm ml 3 5ml 30ml 300ml 30ml 5 500ml L 1mL 50ml ml 100ml 100ml ml 15ml 1ml -d 8 -d 10 1µg/ml 1ml 0.5ml -d 10 g/ml ml 0.5mL III-10
52 N,O-bis(trimethylsilyl)trifluoroacetamide 200 L mL 1mL 1000mL 20g g 100mg 1000mg/L -d GC/MS GC 30m 0.25mmI.D. d f =0.25 m L He 40cm 280 MS EI 70eV 250 III-11
53 SIM TMS PTRI=Programmed Temperature Retention Index PTRI TMS ,4- TMS TMS TMS d PTRI n- ml 0.5mL L GC L GC 15 GC/MS 20 III-12
54 µg/ml ng ml GC L ml µg/g ng ml GC L g 100 L mL SS Sep-Pack SP- 2 Oasis TM HLB SDB-RPS 15 30ml III-13
55 2,4- TMS TMS N,O-bis(trimethylsilyl)trifluoroacetamide -d III-14
56 1.0mL No ph GC/MS L (30g) 1.0mL ph =3 3.5 Yes 50mL A No ph GC/MS L (30g) 0.5mL BSTFA ph =3 3.5 Yes 0.2mL 50mL
57 20g 20g GC/MS A 20g 20g GC/MS BSTFA
58 4-t- 4-n- 4-n- 4-n- 4-t- 4-n g/l 0.1 g/l 1.0 g/kg 10 S/N=3 g/l g/kg 4-t n n t n n A KOH GC/MS-SIM GC/MS-SIM 17
59 10 10 n- Sep-Pak Plus PS-2 Sep-Pak R Cartridges Florisil R 10ml 4ml 10ml 18
60 5ml 10ml 3ml 10g 100ml 30ml rpm ml 20ml 5% 200ml 50ml 50ml 50ml 10g 100ml 30ml rpm ml 1N-KOH 0.5ml 0.2ml 10 1N-KOH 5ml 70 8ml 0.5 g/ml 1.0ml 10ml 0.7ml 3ml 4% 1ml 4% 10ml 19
61 4% 8ml 0.5ml 10g g 10 g 100 g/ml 1000 g/ml 1.0 g/ml 10 g/ml a 25m 0.32mmI.D.,d=0.52 f m 5% l He 7.5psi 250 b 70e SIM c 20
62 4-t n n t n n A t- 4-n- 4-n- 4-t n g/ml 10 g/ml 1.0ml 10ml 1N-KOH 0.5ml 0.2ml 10 1N-KOH 5ml 8ml 0.5 g/ml 1.0ml 0.7ml l GC/MS 15% 21
63 15% GC/MS 20% g/l ng ml g/g ng 1000 JEOL DX-303 1/ g/ml 3ml 2.7ml 0.1ml 1/10 2,4-22
64 10ml 10ml 20ml/min 0.3ml 1N KOH 23
65 1/10 24
66 10
67 1 ( 1) -n- * * -2- * ( 2) 2 -n g/l 0.2 g/l -n g/kg 10 g/kg -n GC/MS-SIM ( ) GC/MS-SIM 5 GC/MS-SIM ( ) / SIM / 5 GC/MS-SIM -1
68 4 4.1 ( 3) L ( 4) ( ) ( 5) ( 6) -d -d -n- -d -n- -d -2- -d -d -d 4- -d -d -d -d -d -d -d PCB ( 7) ( 8) ( 9) ( 10) 5 5 (W/V) (60/100 ) g -2
69 5.7mL 4 5 ( ) cm 1cm 2g 1cm, 2 ( 11) SPC ( 11) ( 11) ( GPC) 8 20mm 300mm ( 12) HPLC GPC GC/MS (1) ( 13) 95ml SPC 100ml( 14) ( 15) 15g( 16) 2.5ml( 17) ( 18) 1 4 ( 19) 1ml( 20) -3
70 GC/MS ( 21) ( 22) GPC GC/MS (2) ( )20g 100ml ( 15) ( 23)30ml rpm /4 15ml SPC 1 5ml( 24 25) GPC ( 26) SPC 1ml ( 25) GC/MS ( 21 27) 1/4 15ml 5 100ml 300ml 25ml 40 ( 28) 10ml 1ml / 50ml( 29) ( )100ml( 30) 1ml / 40 ( 28) 10ml 1ml( 20) GC/MS ( 21 27) GC/MS (3) 20g 200ml ( 15) ( 23)30ml rpm 10 1/4 15ml SPC 1 5ml( 24 25) GPC ( 26) SPC 1ml ( 25) GC/MS ( 21 27) 1/4 15ml -4
71 5ml 5 20ml 5 100ml 300ml 25ml 40 ( 28) 10ml (10 300mm 2g 1cm ) 1ml / 50ml( 29) ( )100ml( 30) 1ml / 40 ( 28) 10ml 1ml( 20) GC/MS ( 21 27) GC/MS 6.2 GPC ( 31) GPC ( 12) ( 32) ( 8mm Shodex AsahipakGF-310HQ ml/min) ( 33) 1000mg/L GPC 100mg/L ( 0.1mg/L) 1000mg/L ( 1 10mg/L) -5-5
72 6.5 GC/MS (1) ( 34) 30m 0.25mmi.d m 5% 50 (2 ) l 40cm ( ) 270 (2) EI 70V ( 35) (3) (m/ ) 149 (m/ ) 177 -n n n (m/ ) 153 (m/ ) 4- -d 130 -d 136 -d 164 -d 188 -d 212 -d 240 -d GC GC ( 36) -6
73 1 GC 1 GC GC g/ml g/g (ng) (ml)/ ( l) 1/ (ml g) 20g 1/4 1 GC n- DBP DEHP 1000 PCB 1000 PCB HPLC DBP DEHP PCB DBP DEHP 1 3-7
74 Giam SPC 12 Shodex AsahipakGF-310HQ 13 EPA method506 PID EPA method525.2 GC/MS 6 8 SPME 14 SPC 15 DBP DEHP (1 2 ) Speed98' Speed98' ml
75 GPC 8mm GPC mm GPC 1 2ml 25 SPC GPC THF GC GC 35 SIM 36-9
76 ( ) ) 7. EPA:Method 8270B, US EPA 8. EPA:Method 525.2,USEPA 9. EPA:Method 506, USEPA -10
77 1-2- (DEHA) g/l 10 g/ 3 GC/MS-SIM 5 GC/MS-SIM ( 1) / 5 GC/MS-SIM ( 1) -2- ( 2) ( 3) 1L ( 4) ( ) 4.2-1
78 PCB 1000 ( 5) DEHA DEHA-d8 -d10 PCB ( 6) ( 7) 5 5 (w/v) 5 5 (w/v) (60/100 ) g 5.7ml cm 1cm 2g 1cm SPC SPC GC/MS -2
79 6 6.1 (1) ( 8) 1000ml 2L ( 9) ( 10) ( 11)50g 100ml 5 100mL 30 ( 12) 10ml 1ml( 13 14) (2) ( )20g 100ml ( 10) ( 15)50ml rpm ml( 16) 1000ml 100ml 30 10ml 5ml (3) 20g 100ml ( 10) ( 15)50ml rpm 10 10ml 5 20ml 5 500ml( 16) 1000ml 100ml ml 5ml 6.2 (1) GC/MS ( 17) GC/MS -3
80 (2) (10 300mm 5g 1cm ) 1ml / 50ml( 18) (1 100)100ml( 19) 1ml / 30 10ml 1ml( 14) GC/MS ( 17) ( 20) ( 21) GC/MS ( 22) DEHA 1000mg/L (DEHA-d) 8 DEHA 100mg/L ( 0.1mg/L) ( -d 10) DEHA 1000mg/L ( 1 10mg/L) GC/MS ( 23) 30m 0.25mmi.d m 5% 50 (2 ) l 40cm ( ) 270 EI -4
81 70V ( 24) (m/ ) DEHA 129(147) (m/ ) DEHA-d8 137 (m/ ) -d DEHA 1 GC DEHA 5 DEHA -d10 1 GC DEHA -d10 5 DEHA DEHA-d8 6.7 ( 25) 1 GC DEHA 1 GC DEHA -d10 GC DEHA DEHA g/ml g/g (ng) (ml)/ ( l) 1/ (ml g) 1 GC DEHA DEHA-d8 DEHA-d 8 DEHA (DEHA-d 8) ( -d 10) (DEHA-d)
82 , -2- GPC DEHA DEHP DEHP 300 GC/MS DEHA EPA method506 PID EPA method525.2 GC/MS 1 5ml DEHA PCB 12 K.D. 5ml DEHA 0.25ml
83 DEHA 20 (10 300mm 5g 2cm ) 50ml (5 95)50ml g 5g (10 300mm 5g 5, ) 50ml (2 98)50ml 5g 5 95g 30 G 100g 2L 1L 30 1L 1L DEHA DEHA-d 8 -d10 DEHA 23 GC SIM 25-7
84 EPA:Method 8270B, US EPA 5. EPA:Method 525.2,USEPA 6. EPA:Method 506, USEPA -8
85 [a] (BaP) g/l 1 g/kg GC/MS-SIM ( 1 3) BaP GC/MS-SIM 4- ( ) ( 4) GC/MS-SIM GC/MS-SIM GC/MS-SIM ( 5) 1 L Na 2 SO ml 2 1 ml GC/MS 0.3 ml BaP 4- Na2SO4 GC/MS
86 Na2SO4 GC/MS Na2SO4 GC/MS Na2SO4 GC/MS (1) ( 6) ( 7) BaP ( 8) 4- ( 9) 1,3- (DPP) cis-1,2- (cis-dpcb) trans-1,2- (trans-dpcb) 2, (DPB) ( 10) 2,4, (TPH) (1'- ) (PPET; 4 ) 1,3,5- (TPCH) BaP-d12 -d10 -d10 1,2- -d14 d12( 11) 100 mg 100 ml BaP 100 ml 1000 g/ml 10 ml 100 ml 100 ml 1 ml 100 g ( 12) 100 mg 100 ml BaP-d ml 1000 g/ml
87 10 ml 100 ml 100 ml 1 ml 100 g ( 13) ( 1 cm 30 cm) 5 % ( 14) 5 g 2 cm 10 ml ( 7 mm) ( ) 2cm ( 15) 5% NaCl 5%(W/V) 1 M 28.1 g 500 ml (2) ( 1L ) ( 1L) ( ml) ) ( ml) ) ( ) KD GC/MS GC MS ( 16) (1) ( ) (4 ) ( ) (2) ( ) 1 L 2 L ( 17) 50 g 100 ml 5
88 100 ml 5% NaCl 50 ml 5 KD 5 ml ( 18) 1 ml ( 19) ( ) (a) BaP (b) 4-20 g 1 L ( 20) ( 2) 200 ml 10 g 20 ml 10 ( 21) 20 ml 10 ( 22) KD 5 ml 1 ml (c) ( 23) 20 g ( ) 200 ml ( 2) 1 M 100 ml ml 3000 rpm 10 5 % 400 ml 1 L 100 ml ml 5 % 50 ml 2 KD ( 18) 5 ml 1 ml ( ) (a) BaP (b) 4-20 g 100ml ( 2) 50 ml rpm ml 1 L 300 ml ( 21, 24) 10 g 20 ml ml 10 ( 22) ( 25) KD 5 ml 1 ml ( 23)
89 ( ) ( 5) 20 ml - (5:95 V/V) 100 ml ( 26 27) KD 5 ml 0.3 ml 10 l 1 L GC/MS ( 28) (3) (4) g/ml (5) ( ) GC/MS ( 29) (a) GC 50% ( mm m ) ( 30 32) 50 ( ) 20 / 300 (30 ) 250 ( 40 cm ) (1 ) (b) MS :EI 70eV 300 A 230 (c) ( 33 34) BaP 252 (250) 105 (182) (91) DPP 92(196) cis-dpcb trans-dpcb 104 (208) DPB 91 (208) TPH 91 (207) PPET 129 (207) TPCH 104 (208) BaP-d d d d ,2- -d d ( ) (6) 0.3 ml 10 l 1 l GC/MS
90 ( 26 34) (7) ( g/l) (ng) (ml) ( l) (L) 1) GC/MS [a] [e] 2-3- GC/MS SIM 2) GC/MS BaP BaP-d12 -d d5 1,2- -d14 3) (ODS) ( 1 m 450 ) 3000 rpm 10 4) 5) PR ( ) ( ) ( FL LC- Florigil 5 10 g ) ( 1 cm
91 30 cm) 7 g 2 cm ( ) 6) 7) ) BaP 9) 10) 11) -d8 -d10 -d10 p- -d14-13 C6 (HCB- 13 C6) 12) 13) SI (5 g) LC-Si (5 g) ( ) 14) 5 % C-200 ( ) g 5 ml ) 16) BaP 17) ( ) 3000 rpm 10 18) 30 19) 0.3 ml 10 l 20) 30 ml 21) 22) 20 g 500 ml ( 1b) 5 g 5 10 ml 90 23) BaP 24) 100 ml 300 ml 25) 26) -
92 (5:95 V/V) 27) GC/MS 28) 29) GC ) DB-17 TC-17 HP-50+ SPB-50 ( ) 31) PET DB-WAX ( ) 32) PET DB-1 HP-1 DB-5 HP-5 ( ) 33) 11 -d d d p HCB- 13 C ) BaP BaP-d12 -d d5 1,2- -d14 d10 d 12 1) 1 (1995). 2 (1991) (1989) (1981). 5 EPA: Method 8270B, US EPA. 6 EPA: Method 525, US EPA. 7 39, (1998). 8.
93 1, (DBCP) n g/l 1 g/kg GC/MS-SIM ( 1 3) GC/MS NaCl GC/MS NaCl (1) ( 4) DBCP n- ( 5) ml 100 ml DBCP n- 100 mg 100 ml ( 6) ml 100 ml mg 100 ml ( 7) ml 100 ml 10 ml 100 ml (2) ml ml ml 105 3
94 ( ml) ( 8) ( 9) ( 10 11) GC/MS GC MS (1) ( ) (4 ) ( ) (4 ) ( 12) (2) ( ) ( 13) ml 1 l ( ) 20 g 3000 rpm ml rpm ml rpm 10 (25 50 ml) ( 13) 9.4 ml 0.6 ml ml ml ( 14) 1 l ( ) GC/MS ( 15) (3)
95 (4) 10 ml 1 10 ml (100 g/ml) 1 50 g/ml (5) ( ) ( 16) 10 psi ( ) GC-MS (a) GC ( mm m m ) ( 17) 35 (3 ) 10 / 230 (7 ) 200 ( 40 cm/ ) (1 ) (b) MS EI 70eV 300 A 230 (c) DBCP 75 (157) 104 (78) n- 134 (91) ( ) (6) g/l ( 18) 1 l GC/MS (7) ( g/l) (ng) (ml)
96 1) GC/MS ( ) ( ) 1,2-1,1,1-1,1,2-1,1- cis-1,2- trans-1,2-1,2-1, ,4-2) SIM 3) % 4) 1 3 L 1/3 5) (1 mg/ml) 6) 7) 8) 9) 10) 11) ml ) 13) 30 % 14) 90% 9.4 ml 0.6 ml ml 15) GC/MS 16) 17) VOCOL Aquatic DB-624 DB-WAX DB-1301 ( ) 18)
97 1) 1 (1993). 2 (1994). 3 JIS K0125 (1990). 4, 7, (1997).
98 1, (DBCP) n g/l 1 g/kg GC/MS-SIM ( 1 3) GC/MS GC/MS GC/MS (1) ( 4) DBCP n ml 100 ml 1 ml 100 ml (2) 5 25 ml ( 5) ( 6) GC/MS GC MS
99 (1) ( ) ( ) (2) ( ) 5 25 ml 1 l ( ) 9.8 ml 0.2 ml ml ( 7) 1 l ( ) 20 g 3000 rpm ml rpm ml rpm 10 (25 50 ml) 9.8 ml 0.2 ml ml ( 7) 1 l ( ) GC/MS ( 8 10 (3) (4) (5) ( ) ( 8 10)
100 ( GC-MS (a) GC ( mm m m ( 11) 40 (5 ) 7 / 230 (5 ) 180 ( 40cm/ ) (b) MS EI 70eV 300 A 230 (c) DBCP 75 (157) 104 (78) n- 134 (91) ( ) (6) ng ( 12) 1 l GC/MS (7) ( g/l) (ng) (ml) 1) GC/MS 2) SIM 3) GC/MS ( ) ( ) 1,2-1,1,1-1,1,2-1,1- cis-1,2- trans-1,2-1,2-1, ,4-4)
101 5) 6) 7) 90% 9.8 ml 0.2 ml 5 25 ml 8) 9) GC/MS 10) 11) VOCOL Aquatic DB-624 DB-WAX DB-1301 ( 1) 12) 1) 1 61 (1987). 2 (1993). 3 (1994). 4 JIS K0125 (1990). 5 EPA: Method 624, US EPA.
102 N- 1) 2) 1) GC/MS HPLC GC/MS 2) 0.01~0.05µg/l 0.5~50µg/kg GC/MS SIM GC/MS SIM GC/MS SIM a) b) -d 10 -d 10 -d 12 -d 12 c) d) 600 C 4 e) % f) a) b) - IX-1 -
103 c) (ODS) 200-1,000mg 5ml 5ml 5ml d) e) 3ml 1g f) 3ml g g) KD h) i) j) 1µm k) / (GC/MS) a) SS 50µg/ml 1µm 5% l 50g 50ml ml 100ml 4 KD 2ml 3) 200ml 4) b) 1µm 5-10ml 500ml 10ml 10ml 10 3ml 20% / 10ml 2ml 5ml 2ml - IX-2 -
104 - IX-3-10~25g 25ml ,000rpm % 400ml 1l 50ml ml 100ml 10 30g 50ml KD 2ml KD 10ml 250ml 5% 5~10ml/min 10ml 10 3ml 20% / 10ml 2ml 5ml 2ml 5) 10~25g 50ml ,000rpm 15 50ml 1l 30ml 5 30ml 5 5ml 5% 500ml 50ml 10 50ml 40 C 10ml 10ml 2ml 5) 5% 5.2
105 10ml 5~10ml 1ml 2 10ml 20% 10ml 2ml Envi-Carb 3ml 0.25g 20% 10ml 50% 5ml 2ml 130 C 10g 1.0 ~1.5 30cm 2g 10ml 2ml 100ml 20% 2ml 0.5ml GC/MS 100µg/ml 1.0µg/ml 6) 0-1.0ml 0.5ml 0.5ml -d 10 -d 10 -d 12 -d µg/ml 6) - IX-4 -
106 a) GC/MS (GC) 0.25mm 30m 0.25µm 50 C 1min -20 C/min-200 C -5 C/min-280 C(5min) min 40-50cm/sec (MS) 280 C 270 C 70eV 300µA (EI) MS DFTPP (decafluorotriphenylphosphin) PFTBA(Perfluorotributylamine) PFK Perfluorokerosene MS (M/Z) IS-1 -d IS-2 -d IS-3 -d IS-4 -d (215) IS (188) IS (186) IS (291) IS (115) IS (127) IS (202) IS (335) IS (144) IS (181) IS-4 - IX-5 -
107 (167) IS-4 (2 ) (167) IS-4 (2 ) (163) IS (212) IS-1 b) 2µl GC/MS c) 2µl GC/MS d) C µg/l S abs ng V conc ml V inj GC/MS µl V spl ml GC/MS 5 (s) 3s (µg/l kg) 10s (µg/l kg) C( µ g / l) = S ( ng) Vconc( ml) 1,000 abs V ( µ l) V 10 1 ±20% 2 10% 2 30% inj spl ( ml) - IX-6 -
108 2,4,5-2 4-D 2,4-2,4,5-T 0.05µg/l 5~10µg/kg ph2 GC/MS SIM 1N - 1:9 ph2 20% / GC/MS a) 2,4- (2,4-D) b) 2,4,5- (2,4,5-T) c) -d 10 d) 2,4- e) f) g) 600 C 4 h) N- -N - -N- i) j) k) l) a) b) c) d) e) f) g) h) 3ml 0.5 1g : i) / (GC/MS) - IX-7 -
109 - IX ) 1l 25g 20% ph2 100ml ml 25 C 2) 10ml 1N 10ml 10ml 70 C 15 3) 100ml 30ml 5 4) 20% ph2 30ml 10 30ml 25 C 1) 2) 3) 2,4-D 2,4,5-T 4) 10~25g 50ml 2,4-20µg/ml 0.1ml 1N - 1:9 20ml ,000rpm 10 1N - 1:9 20ml 2 25 C + 5ml 1N 10ml 70 C ml 30ml 5 20% ph2 20% 50ml 10 20% 50ml 3 20% 25 C 10~25g 2,4-20µg/ml 0.1ml 1N - 1:9 30ml ,000rpm %
110 0.5ml / 1ml 5) d µg/ml 10µl 5) N- -N - -N- 10% / 5ml 20% 5ml 0.5ml ,4-D 2,4,5-T 100mg 100ml 1,000µg/ml 10µg/ml -d 0.5µg/ml a) GC/MS (GC) 0.25mm 30m 0.25µm 50 C 1min -20 C/min-200 C -5 C/min-280 C(5min) min 40-50cm/sec (MS) 280 C 270 C 70eV 300µA (EI) m/z188 -d 10 - IX-9 -
111 m/z ,4-D-Me m/z ,4,5-T-Me b) 0-1.0µg/ml 5 0.5ml / 1ml 1 0.5ml -d µg/ml 10µl 2µl GC/MS c) 2µl GC/MS d) C µg/l S abs ng V conc ml V inj GC/MS µl V spl ml GC/MS 5 (s) 3s (µg/l kg) 10s (µg/l kg) C( µ g / l) = S ( ng) Vconc( ml) 1,000 abs V ( µ l) V 10 1 ±20% 2 10% 2 30% inj spl ( ml) - IX-10 -
112 2- MBC: Methylbenzinidazol-2-yl carbamate MBC 0.1µg/l 2µg/kg 20µg/kg MBC 1.52 /MBC GC/MS 0.1N ph2 GC/MS 0.1N a) 98% b) -d 10 c) d) e) 600 C 4 f) N- -N - -N- g) h) PCB i) j) a) b) c) d) e) KD f) g) / (GC/MS) - IX-11 -
113 - IX l 50g 50ml ml 1) ml 100ml 0.1N 50ml 5 5N 0.2N ph ml 50ml 5 50ml 50ml KD 3-5ml 1) 200ml 2) N- -N - -N- 10% / / 10 25g 50ml ,000rpm 10 50ml 40 C 0. 1N 30ml 50ml 200ml 5 50ml 40 C 50ml 100ml 0.1N 30ml 5 0.1N 20ml 5 5N 0.2N ph6.4 50ml 5 30ml g 50ml ,000rpm 10 50ml 30ml 2 40 C 0.1
114 0.1N 30ml 50ml 0.5ml / 1ml 2) 1 -d µg/ml 0.2ml mg 100ml 1,000µg/ml 1ml 0.2N 50ml 100ml 5 5N 0.2N ph g 20ml MBC 100ml 2 100ml 10µg/ml MBC ml 0.5ml / 1ml 1 -d µg/ml 0.2ml MBC 1.52 a) GC/MS (GC) 5% 0.25mm 30m 0.25µm 50 C 1min -20 C/min-200 C -5 C/min-280 C(5min) min 40-50cm/sec (MS) 280 C 270 C 70eV 300µA (EI) m/z188 -d 10 m/z MBC-Me - IX-13 -
115 b) 2µl GC/MS c) 2µl GC/MS d) C( µ g / l) = S ( ng) Vconc( ml) 1,000 abs V ( µ l) V ( ml) C µg/l S abs ng V conc ml V inj GC/MS µl V spl ml GC/MS 5 (s) 3s (µg/l kg) 10s (µg/l kg) 10 1 ±20% 2 10% 2 30% inj spl 3- -1,2,4- - IX-14 -
116 1µg/l 1µg/kg ph4.0 ODS HPLC- 2% o- HPLC 40% HPLC a) (amitrol) 3- -1,2-,4-98% b) (fluorescamine) (fluram) c) 0.1M (ph9.5)50ml o- 5ml(5ml 270mg o- ) 2-0.2ml 2-50µl d) 60g 16.4g 600ml ph e) f) 700 C 4 g) h) No.5C 5 C i) ODS j) k) AG50W-X8 l) IRC-50 a) b) c) d) e) f) g) - IX-15 -
117 5 C 20ml 50ml 2ml (ph4.0) 1) 0.2% - 4ml 2) 2 20 C 50ml 17g 1N 1ml 5-10ml ODS 2ml 2ml 3, 4) 1) ph ) 0.2% - 4ml 15-30% 0.2% - 3) o- o- 1 R-NH 2 - o- 4) g 50ml 2% 10ml 10 3,000rpm 5 No.5C 2 100ml 0.1M ph9.0 10ml 20ml 50ml o- 1ml 10 O- 10ml ml 10 25g 20ml 5 5 3,000rpm 10 40% 20ml 50ml 20ml 5 / 100ml 10ml 1ml 75 C 30 10ml 5) 10ml 2.8% 12ml n- 30ml 45 5ml 6) 5ml 50ml 2.8% 35ml n- 100ml 0.1M 2ml 1ml 0.2% / 0.1ml 1 0.1M 0.5ml HPLC - IX-16 -
118 6) 10mm 300mm µm 1ml 5ml 7) µm 5ml 1N 2.8% 1N mg 100ml 1,000µg/ml 5µg/ml 5 a) HPLC- ODS 5mm 15cm 5µm 40 C 9% - 10:9 2ml/min 395nm 480nm b) 10ml 1ml 1ml ph ml 0.2% - 0.4ml 2 20 C 10ml 0.5µg/ml 20µl HPLC -20 C 1 o- c) 20µl HPLC d) C( µ g / l) = S ( ng) Vconc( ml) 1,000 abs V ( µ l) V ( ml) C µg/l S abs ng inj spl - IX-17 -
119 V conc ml V inj HPLC µl V spl ml HPLC 5 (s) 3s (µg/l kg) 10s (µg/l kg) 10 1 ±20% 2 10% 2 30% N- 0.03µg/l 2µg/kg 1µg/kg N- CH 3 NH 2 o- OPA OPA 10% 10% HPLC - IX-18 -
120 a) 99% b) c) d) e) o- 2- f) g) 650C 24 h) i) j) k) l) 99.99% a) b) c) d) KD e) f) g) HPLC l l 100g 70g 50 ml ml 100ml 2, 3, 30 C 4) 1µg/ml / 1:9 1ml 5) 1) 200ml 2) 30 C 3) KD 4) 50ml 5% - IX-19 -
121 - IX-20-1g 10ml 10% 20ml 5) HPLC 10 25g 100ml 50ml ,000rpm 10 50ml 10% 500ml l 50ml 5 l 50ml 50ml 5 50ml 2 10ml 30 C 10~12mm 300mm 5% 1g 2cm 10ml 50ml 10% / 20ml 1ml 1µg/ml : 1:9 1ml mg 100ml 1000µg/ml 1: µg/ml µg/ml 10 a) HPLC ODS (1:9)
122 1ml/min 40 C 1 50mM 100 C 0.4ml/min 2 o- / 50 C 0.4ml/min 345nm 450nm b) 20µl HPLC c) 20µl HPLC d) C µg/l S abs ng V conc ml V inj HPLC µl V spl ml HPLC 5 (s) 3s (µg/l kg) 10s (µg/l kg) C( µ g / l) = S ( ng) Vconc( ml) 1,000 abs V ( µ l) V 10 1 ±20% inj spl ( ml) - IX-21 -
123 2 10% 2 30% 1) (1993).. 2) (1983) 1- (NAC). 57, pp , ( 58 5 ) 3) (1988) (BPMC MTMC PHC MIPC X MC NAC methyl 2-benzimidazol carbamate). 62, pp83-99, ( 63 6 ) 4) (1992). 3, pp35-54, ( 4 6 ) 5) (1993) P (MEP) (MPP) (EDDP) EPN (PMP) α- (α-cvp) β- (β-cvp). 4, pp65-94, ( 5 6 ) 6) (1994). 5, pp35-55, ( 6 6 ) 7) (1996) 2,4- p-t-. 7, pp , ( 8 6 ) 8) (1984) 3- -1,2,4-. 58, pp , ( 59 5 ) 9) (1992). 3, pp55-68, ( 4 6 ) 10) (1994) N-. 35, ) (1977). 2, GC/MS LC/MS GC/MS/MS - IX-22 -
124 , 150g, 50ml 1.0l 0.5 1l 0.5l SS:50mg/l 10, 2 GC/MS IS: phenanthrene-d 10, fluoranthene-d 10 chrysene-d 12, perylene-d 12, 25ml 3, 10 25g, 3,000rpm, %, 400ml, 50ml 2, 10, 10ml, 250ml 10ml 20% / 10ml, 50ml 2 50% / 10ml,, 10~25g 10 3,000rpm, 10 5%, 500ml, 50ml 2, 30ml 3, ml 20% / 100ml 1 - IX-23 -
125 ,, 25g 100ml 2, 10ml 1N, 10ml, 10ml 1l, 30ml ph, 20%, 10 20%, 30ml 2, 25 70, 15, 5 ph 2, 10, 0.5ml /, 1ml GC/MS, 1, 5ml 20% /, 5ml IS: 2,4-1N / 1:9, 20ml 2 IS: -d g, 10 3,000rpm, 10, 10ml 1N, 10ml 20% /,, 10ml 20% 5ml 2 ph 2 70, 15, 0.5ml /, 1ml, 10 IS: 2,4-1N / 1:9, 20ml g, IX-24 -
126 NaCl, 150g, 50ml, 10 20ml, 1, 10, 50ml 3 0.1N, 50ml 5N 0.5N, 10 20ml, 50ml 2, 5 ph (6.5),50ml 2 GC/MS, 1 IS: phenantherene-d 10, 0.5mg/ml, 0.2ml 10 25g, rpm, N, 30ml, 50ml 0.1N, ml 5N 0.5N, 50ml 2 ph (6.5) GC/MS IS: -d10,50ml 2 30ml 2, 10 25g rpm, N, 30ml, 50ml 0.1N, 30+20ml 5N 0.5N ph (6.5), 50ml 2 GC/MS IS: -d IX-25 -
127 , No.5C, 17g 1N, 1ml, 2ml ODS, 5-10ml/min, 20ml 2M ph4.0, 2ml 0.2%, 4ml!! ph !! 20, 2!!!! HPLC-, 2ml ODS 9% - (10:9) 395nm, : 480nm 2%, 20ml g O-, 1ml, 2ml, M (ph9.0), 10ml No.5C (ph4.0), 2ml 0.2%, 5ml, 17g 1N, 1ml, 2ml HPLC-, 20ml 40%, 2 4 ODS, 5-10ml/, g, 100ml, 10ml, 5ml, 1ml 70, 30 50ml 50ml 2 n- 10ml, 2.8% 12ml n-, 100ml 50ml, 2.8% 35ml 0.05M, 2ml 0.25% /, 0.1ml 0.1M, 0.5ml HPLC- ODS - IX-26 -
128 , 100g, 100ml, 1l, 10 3, 50ml 2, 50ml IS: 1mg/l, 1ml HPLC - [ 10%, 500ml 10~25g, 10 HPLC - IS: 1mg/l, 1ml 10ml 10% / 10ml, 50ml 2 10%, 500ml 10~25g, 10 10ml 10% / 10ml HPLC - IS: 1mg/l, 1ml 5 - IX-27 -
129 X-1
130 X-2
131 X-3
132 X-4
133 X-5
134 X-6
135 X-7 +
136 XI-1 -
137 XI-2
138 XI-3
139 XI-4
140 XI-5
141 XI-6
142 XI-7
143 XI-8
144 XI-9
145 XI-10
外因性内分泌攪乱化学物質調査暫定マニュアル（水質、底質、水生生物）
(PCB) 1 ng/l (µg/kg, wet) (µg/kg) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001) 1 (0.001) 10 (0.01) 1 (0.001)
外因性内分泌攪乱化学物質調査暫定マニュアル（水質、底質、水生生物）
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外因性内分泌攪乱化学物質調査暫定マニュアル（水質、底質、水生生物）
N- 1) 2) 1) GC/MS HPLC GC/MS 2) 0.01~0.05µg/l 0.5~50µg/kg GC/MS SIM GC/MS SIM GC/MS SIM a) b) -d 10 -d 10 -d 12 -d 12 c) d) 600 C 4 e) 1 99.999% f) a) b) - IX-1 - c) (ODS) 200-1,000mg 5ml 5ml 5ml d) e)
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3--2-3-Iodo-2-propynyl butylcarbamate (IPBC) Carbamic acid, butyl-, 3-iodo-2-propynyl ester Iodocarb CAS 55406-53-6 C 8 H 12 NO 2 I C (g/cm 3 ) (mmhg) log P ow 281.09 (280.9910) 64 68 1.51 1.57 (20 C)
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2,2-2,2 -Iminodiethanol Diethanol amine CAS 111-42-2 C 4 H 11 NO 2 105.1356-105.0790-28 C 1) 1.0881 g/cm 3 1)
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2,4-2,4-Dimethylaniline 2,4-2,4-Xylidine CH 3 CH 3 CAS 95-68-1 C 8 H 11 N 121.18 121.0892-14.3 C 2) 214 C 2) 0.9723 g/cm 3 2) 0.133 mmhg (25 C) 1) 1390 mg/l (25 C) 1) 3.710 3 mg/l 25 C WSKOWWIN 5) 6.0710
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Welcome to the 2012 New Catalogue 1 2012 PRODUCTS TABLE OF CONTENTS DFP-CVS-B10 5 DFP-CVS-B1 7 DF-CVS-A10 9 DF-CVS-A5 11 DF-CVS-B10 13 DF-CVS-C10 15 PCB-CVS-A10 PCB-CVS-A5 PCB-CVS-B10 17 19 21 DFP-LCS-B
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Simplify Sample Preparation [ SAMPLE PREPARATION SOLUTIONS ] [ OASIS SAMPLE-EXTRACTION PRODUCTS ] LC-MS HPLC UPLC 1 [ SAMPLE PREPARATION SOLUTIONS ] [ OASIS SAMPLE-EXTRACTION PRODUCTS ] 2 [ OASIS SAMPLE-EXTRACTION
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LC/MS/MS による類分析 日本ウォーターズ株式会社 15 Waters Corporation 1 対象化合物 - クロロ (-CPh) 4-クロロ (4-CPh),4- ジクロロ (,4-DPh),6- ジクロロ (,6-DPh),4,6- トリクロロ (,4,6-TPh) 15 Waters Corporation 1 サンプル調製 ( 検量線 標準液 ) 5 標準溶液添加 (,,4,,,5uL)
表 1. HPLC/MS/MS MRM パラメータ 表 2. GC/MS/MS MRM パラメータ 表 1 に HPLC/MS/MS 法による MRM パラメータを示します 1 化合物に対し 定量用のトランジション 確認用のトランジションとコーン電圧を設定しています 表 2 には GC/MS/MS
ACQUITY UPLC TM /MS/MS と GC/MS/MS によるベビーフード中の残留農薬の分析 No. 720007 20001436J 概要 EU の Baby Food Directive 2003/13/EC 1) では ベビーフード中の使用が禁止されている残留農薬について明示しています その濃度が 0.003mg/kg を超えているのか あるいは 0.004-0.008mg/kg
ソリッドコアUHPLCカラムとUHPLCシステム、質量分析計を利用した違法薬物の高速スクリーニング分析
UHPLCUHPLC Application Note CC2999 Vanquish Accucoreopiates benzodiazepines amphetamines Thermo Scientific Accucore Vanquish C18 UHPLC1.5 m Vanquish UHPLC 47 UHPLC Vanquish UHPLC Accucore Vanquish UHPLC