Mechanism of Action of Electrogenic (Na, K)-ATPase Plasma membrane (Na, K)-ATPase transports 3 Na + out of and 2 K+ into the cell, and thus the pump i
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1 Mechanism of Action of Electrogenic (Na, K)-ATPase Plasma membrane (Na, K)-ATPase transports 3 Na + out of and 2 K+ into the cell, and thus the pump is electrogenic. This review describes experiments on topical aspects of the cation movement mechanism of (Na, K)-ATPase, putting emphasis on electrogenic properties, reconstitution, and cation occlusion or deocclusion from the transport enzyme molecule. Key words : (Na, K)-ATPase, Electrogenic pump, Reconstitution, Cation occlusion, Amine inhibition
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