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1 81 J u l y 2010
2 81 J u l y 2010
3 Cosmo Bio News No.81 1
4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 F 4 2 Cosmo Bio News No.81
5 347 bfbfbf B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 B 4 C 4 B B 4 Hycult Biotech TEL FAX Cosmo Bio News No.81 3
6 4 Cosmo Bio News No.81
7 347 PCR - TCRExpressKit + DNA (spectratyping) PCR - + V 1 V 2 V 3 V 4 V V V 7 V 8 V 1 V 2 V 3 V 4 V V V 7 V 8 V 9 V 11 V 12 V 13 V 14 V 1 V 1 V 17 V 9 V 11 V 12 V 13 V 14 V 1 V 1 V 17 V 18 V 20 V 21 V 22 V 23 V 24 V 8* V 18 V 20 V 21 V 22 V 23 V 24 V 8* Distances %) CDR3 Size (Amino Acid) % 90.00% 80.00% 70.00% 0.00% 0.00% 40.00% 30.00% 20.00% 10.00% 0.00% TCR V families CDR3 size % 90.00% 80.00% 70.00% 0.00% 0.00% 40.00% 30.00% 20.00% % 0.00% TCR V families Pre Immunization Post Immunization 2D figure 3D figure Distances %) Pre Immunization Post Immunization CDR3 length (AA) CDR3 size CDR3 length (AA) TEL FAX Cosmo Bio News No.81
8 F E E E Cosmo Bio News No.81
9 Average arhtritis score rear paws Day 1M - PBS (2mg mab) 4M - Dexa Average paw thickness Day 1M - PBS (2mg mab) 4M - Dexa C 4 TEL FAX Cosmo Bio News No.81 7
10 f f 8 Cosmo Bio News No.81 TEL FAX
11 P10 P13 P14 P1 P23 P24 Cosmo Bio News No.81 9
12 N ew Products & Topics 10 Cosmo Bio News No.81
13 347 C C C C C C C C C C C C O + FeIV S H2O H + R H O FeIII S 7 2e -,2H + oxidase shunt b (1-) OH O FeIII S H2O H + H H O FeIII S 1 H2O2 RH FeIII S 2 autoxidation peroxide shunt shunt 4 (1-) O a (2-) O O FeIII O S FeIII e - H + S e - 3 FeII S 4 O2 TEL FAX Cosmo Bio News No.81 11
14 N ew Products & Topics Chemdea íí C C C C C C C C C C NEW C C NEW C C 12 Cosmo Bio News No.81
15 Cosmo Bio News No.81 TEL FAX
16 N ew Products & Topics c c c F F F F F F F F F F 14 Cosmo Bio News No.81
17 TEL FAX Cosmo Bio News No.81 1
18 N ew Products & Topics e 1 Cosmo Bio News No.81
19 TEL FAX Cosmo Bio News No.81 e e e he
20 N ew Products & Topics e 18 Cosmo Bio News No.81
21 347 TEL FAX Cosmo Bio News No.81 19
22 N ew Products & Topics E E E E 20 Cosmo Bio News No.81
23 347 e e e e e e e F B E TEL FAX Cosmo Bio News No.81 21
24 N ew Products & Topics b 3 e e e F 4 22 Cosmo Bio News No.81
25 Cosmo Bio News No.81 TEL FAX c be b
26 N ew Products & Topics E R 24 Cosmo Bio News No.81 F F E E E TEL FAX
27 Hope in the Laboratory vol.39 EB-2 18 COSMO BIO NEWS EB-2 19 COSMO BIO NEWS EB-2 20 COSMO BIO NEWS A 18A 19A Cosmo Bio News No.81 2
28 E B B B B B B B B B B B B E B B B E C B B B E B B B B B B B B B B B B B B B C C B B B B B B B B B B B B B B B B B B B B B B B B B B C B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B C B B B B B B B B B B B C B B B B B B C B B B B B B B B B B E B B B B C B B B B B B B B B B B B B 2 Cosmo Bio News No.81
29 E B B B B B C B B C B C B B B B B B B B C B B B B C B E B B B B B B B E B B B E E B B B E B B B B B B C B B B B B B B B B C B B B B B B C B E B B B B E B B B E C B B E B B B B B C B B B B B B B B B B B B B E B E B B B B B B B B B B B B B E B B B B B B B B F C B E B B B B B B B E B B B B B B B B B B B B B B TEL FAX Cosmo Bio News No.81 27
30 Catch up! O.D.490nm CONC. (mol/l) NO2-Guanine NO2-cGMP NO2-Xanthine NO2-Guanosine Br-cGMP Br-Guanosine Guanosine Xanthine cgmp Control B B Catch up! E E E E E E E E E E E E 28 Cosmo Bio News No.81
31 347 Catch up! E F F Catch up! TEL FAX B 4 TEL FAX Cosmo Bio News No.81 29
32 Catch up! A B (Anti-Drug-Antibodies, ADA) ELISA BD 4 BD 4 30 Cosmo Bio News No.81
33 347 Catch up! B C Catch up! AF AF 4 AF 4 AF 4 B 4 4 TEL FAX Cosmo Bio News No.81 31
34 e 32 Cosmo Bio News No.81
35 TEL FAX Cosmo Bio News No.81 33
36
CONTENTS November 2007 No.6 1 6 8 1 16 18 18 19 2 26 10 19 11 20 12 21 12 22 13 22 13 23 1 2 1 2 1 16 16 2 17 26 18 18 27 28 30 32 32 33 Cosmo Bio New
http://www.cosmobio.co.jp November 2007 No. 6 13-00162-2-20 URL : http://www.cosmobio.co.jp/ TEL : 03632-9610FAX : 03632-9619 TEL : 03632-9620 CONTENTS November 2007 No.6 1 6 8 1 16 18 18 19 2 26 10 19
H1-2_4_P01.qxd
77 November 2009 77 November 2009 Cosmo Bio News No.77 1 2 Cosmo Bio News No.77 367 b b Cosmo Bio News No.77 3 Cosmo Bio News No.77 367 e h e b Cosmo Bio News No.77 F B 3 E 6 Cosmo Bio News No.77 367 B
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