日本化学療法学会雑誌第54巻第1号
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1 Chlamydophila pneumoniae Chlamydophila psittaci Mycoplasma pneumoniae Legionella pneumophila C. pneumoniae C. psittaci C. pneumoniae C. psittaci M. pneumoniae M. pneumoniae C. psittaci L. pneumophila C. psittaci Key words Chlamydophila pneumoniae Chlamydophila psittaci Mycoplasma pneumoniae Legionella pneumophila I C. pneumoniae C. psittaci M. pneumoniae L. pneumophila L. pneumophila C. pneumoniae C. psittaci M. pneumoniae
2 Table. Criteriaforthediagnosisofpneumonia(accordingto theu.s.fdaguidelinesissuedin998) * Patientsinwhom infiltrativeimagesareseeninachestx-ray photographandabnormalityisseeninatleastitemsofthefollowingsymptoms,findingsorhematologicaltestvalues. Cough Appearanceoraggravationofpurulentsputum Raleorfindingsuggestiveofpneumosclerosisinauscultation Dyspneaorfrequentbreathing Pyrexia(> 38 )orhypothermia(< 3 ) Peripheralwhitebloodcelcountincreased(>,/mm 3 ) orstabneutrophilcountincreased(> %) orwhiteblood celcountdecreased(<,/mm 3 ) Hypoxemia(PaO< 6Tor) tonsilitis 4 7.3% 3 3.4% %.9% 6 7.4% 7 8.% 7.% 4 9.4% 3 6.% 4.% Table. Determinationmethodandjudgmentcriteria Determinationitem C.pneumoniaeIgG(MIF) C.pneumoniaeIgM(MIF) C.psitaciIgG(MIF) C.psitaciIgM(MIF) M.pneumoniae(CF) M.pneumoniae(PA) L.pneumophila(IFA) InfluenzavirustypeA InfluenzavirustypeB Judgmentwith singleserum times 3times times 3times 64times 3times 6times Judgmentwith pairedserums L. pneumophila II Table3. Distributionofinfectiousdiseasesaccordingtogeographicarea / Pneumonia/ Pneumonia Numberof patients 4 9.6% % 4.% % % % %.4%.%.% % 6 6.3% % % %.4% 9 3.8% 3.% 39 3.% % 7 8.6%.7% 4 3.6% 3.9% 8 Sendaidistrict 87 Nigatadistrict Okayamadistrict 4 Nagasakidistrict 39.%.% 7.%.% 8 34.% 6 4.9% 3 Total
3 Table4. Rateofpatientspositiveforatypicalpathogensaccordingtoclinicaldiagnosis Clinicaldiagnosis Numberof patients C.pneumoniae C.psitaci Nameofatypicalmicroorganism C.pneumoniae C.psitaci C.psitaci M.pneumoniae M.pneumoniae L.pneumophila Pneumonia tonsilitis / Pneumonia/ %.6% 33.7% 6.% 7.4% 6.3% %.8% 3.4% 3.%.8%.%.6% 4.%.% NT NT NT Total %.3% 8.%.% 8.% Table. Caseswithpairedserasamples with3samples withsamples withsample Sendaiarea Nigataarea Okayamaarea Nagasakiarea (6%) 34(39%) 7(97%) 3(84%) 34(4%) 43(49%) ( %) (%) ( %) (%) ( %) 6( 6%) Total 3 399(7%) 4(%) 9( %) C. pneumoniae C. psittaci C. pneumoniae C. psittaci M. pneumoniae M. pneumoniae C. psittaci L. pneumophila L. pneumophila C. psittaci C. pneumoniae C. pneumoniae C. pneumoniae C. psittaci M. pneumoniae C. psittaci C. psittaci C. psittaci C. psittaci β β
4 Table6. PatientprofilesofC.psitaci-positivecases Clinicaldiagnosis Age Sex Typeofantibiotics Dailydose Period Eficacy Severity Pet,, (injection) (oral) (oral) (injection) 4mg 4mg 3mg 6mg 4mg 4mg mg 3mg 3mg 3mg 3mg 3mg 4mg 3mg 3mg 3mg 3mg 3mg,mg g mg 3mg 3mg 3mg g days 8days 7days 8days 3days 8days days 3days days 7days 3days days days day days 7days day Poor Severe Severe β III C. pneumoniae C. psittaci M. pneumoniae L. pneumophila M. pneumoniae C. pneumoniae C. psittaci C. pneumoniae M. pneumoniae C. psittaci M. pneumoniae C. pneumoniae M. pneumoniae β
5 β C. psittaci C. psittaci C. psittaci C. psittaci β β C. pneumoniae C. pneumoniae
6 Chlamydophila pneumoniae Chlamydophila psittaci Mycoplasma pneumoniaelegionella pneumophila C. pneumoniae C. psittaci M. pneumoniae L. pneumophila L. pneumophila C. psittaci
日本化学療法学会雑誌第57巻第6号
Streptococcus pneumoniae Haemophilus influenzae Moraxella catarrhalis S. pneumoniae S. pneumoniae β β H. influenzae S. pneumoniae H. influenzae M. catarrhalis Key words Otalgia Fever Item Crying,Iritation,
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日本化学療法学会雑誌第56巻第S-1号
Key words Streptococcus pneumoniae µ µ H F Cl H H N N H N F COOH O Fig.1. Sitafloxacinstructure. I γ S. pneumoniae Haemophilus influenzae Table1. Observationandtestschedule Observation/Tests Informedconsent
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日本化学療法学会雑誌第58巻第2号
Key words β Candida Table1. MCFGCPAstudygroup Investigator (representative) YoshitsuguMiyazaki NaoyukiMiyashita RyoichiAmitani KenjiOgawa AtsuyukiKurashima ToshiroKiguchi MichiakiMishima YuichiInoue HiroshiSaito
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日本化学療法学会雑誌第56巻第1号
β β β β β Streptococcus pneumoniaehaemophilus influenzaemoraxella catarrhalismycoplasma pneumoniaechlamydia pneumoniae β Key wordsβ mys nilc laci ngis Table. Assessmentschedule Parameters Patientcharacteristics
日本化学療法学会雑誌第55巻第S-1号
µ µ Key words Streptococcus pneu- moniae S. pneumoniae µ µ I γ H H C HN F F O N O CO H H C SO H H O Fig.. ChemicalstructureofGRNX. γ γ II Haemophilus influenzae Pseudomonas aeruginosa Streptococcus intermedius
日本化学療法学会雑誌第59巻第5号
Streptococcus pneumoniae Haemophilus influenzae Moraxella catarrhalis S. pneumoniae H. influenzae M. catarrhalis S. pneumoniae H. influenzae M. catarrhalis S. pneumoniae H. influenzae M. catarrhalis S.
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日本化学療法学会雑誌第54巻第S-1号
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日本化学療法学会雑誌第56巻第3号
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日本化学療法学会雑誌第57巻第4号
Streptococcus pneumoniae Haemophilus influenzae β β Key words I β Enterococcus faecium Pseudomonas aeruginosa Streptococcus pneumoniae S. pneumoniae Haemophilus influenzae S. pneumoniae H. influenzae Table.
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日本化学療法学会雑誌第60巻第4号
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