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1 Kwansei Gakuin University Rep Title ヒトにおける免疫反応の古典的条件づけ Author(s) Doe, Nobutaka, 土江, 伸誉 Citation 人文論究, 51(4): Issue Date URL Right

究, 51(4): 142-159 Issue Date 2002-02-10 URL http://hdl.

2 psychoneuroimmunology Ader & Cohen, 1993 ; Ader, Felton, & Cohen, 1990, , 2001 e.g., Apanius, 1998 ; Baron, Cutrona, Hicklin, Russel, & Lubaroff, 1990 ; Calabrese, Kling, & Gold, 1987 ; Herbert & Cohen, 1993 ; Jemmott & Locke, 1984 ;

3 Jemmott & Magloire, 1988 ; O Leary, 1990 e.g., Ader & Cohen, 1975, 1982, 1985, 1986 ; Gorczynski, 1990 ; Krank & MacQueen, 1988 ; MacQueen, Marshall, Perdue, Siegel, & Bienenstock, 1989 ; MacQueen & Siegel, 1989 ; O Reilly & Exon, 1986 ; Solvason, Ghanta, & Hiramoto, 1988 ; Solvason, Ghanta, Lorden, Soong, & Hiramoto, 1991 ; Wayner, Flannery, & Singer, 1978 e.g., Buske-Kirschbaum, Kirschbaum, Stierle, Jabaij, & Hellhammer, 1994 ; Smith & McDaniel, Ader & Cohen 1975 conditioned stimulus, CSunconditioned stimulus, US

4 Solvason et al 1988 CS US natural killer, NK NK Ader & Cohen 1975e.g., Ader, et al., 1990 ; Alvarez-Borda, Ramiraez-Amaya, Perez-Montfort, & Bermudez-Rattoni, 1995 ; Dunn, 1989 ; Kelley & Dantzer, 1986 ; Kelley, Dantzer, Mormede, Salmon, & Aynaud, 1985 ; Rogers, Reich, Strom, & Carpenter, CS s-iga secretory immunoglobulin A TUA trimethylundecylenic aldehyde s-iga B

; Kelley & Dantzer, 1986 ; Kelley, Dantzer, Mormede, Salmon, & Aynaud, 1985 ; Rogers, Reich,

5 s-iga s-iga US TUA Kirk-Smith, Van Toller, & Dodd, 1983 CS TUA CSKirk-Smith, et al 1983 TUA Solvason, et al 1988 CS 4 1 s-iga s-iga US e.g., Dalahanty, Dougall, Schmitz, Hawken, Trakowski, Jenkins, & Baum, 1996 ; Naliboff, Benton, Solomon, Morley, Fahey, Bloom, Makinodan, & Gilmore, 1991 ; Ohira, Watanabe, Kobayashi, & Kawai, 1999 ; Pike, Smith, Hauger, Nicassio, Patterson, & McClintick, e.g., Caudell & Gallucci, 1995 ; Landmann,

s-iga US e.g., Dalahanty, Dougall, Schmitz, Hawken, Trakowski, Jenkins, & Baum, 1996 ; Naliboff, Benton,

6 Muller, Perini, Wesp, Erna, & Buhler, 1984 e.g., Sieber, Rodin, Larson, Ortega, & Cummings, 1992e.g e.g., Matthews, Caggiula, McAllister, Berga, Owens, Flory, & Miller, 1995 ; Mills, Dimsdale, Nelesen, & Dillon, s-iga POMS Profile of Mood States

7 McNaire, Lorr, & Droppleman, s-iga enzyme linked immunosorbent assey, ERISA s-iga Kvale & Brandtzaeg, Figure 1 s-iga s-iga ps.01 8 s-iga POMS D , A-H , F Figure 1 s-iga MT STATVTR

Brandtzaeg, 1986 2 Figure 1 s-iga s-iga ps.

8 , C ps.05 D , F F ps.05 s-iga 1 s-iga US s-iga US 5 2 s-iga 1 20 s-iga 20 2 s-iga

9 , 15, 25, POMS 1 2 Figure 2 s-iga 15, 25, 35 s-iga 5 ps ps.05 s-iga 15 s-iga e.g., Graham, Bartholomeusz, Taboonpong, & LaBrooy, 1988 ; Jemmot & Magloire, s-iga POMS 1

10 Figure 2 s-iga s-iga TUA CS US s-iga s-iga

11 TUA CS-US 25 CS 20 TUA CS/US m 5 A4 TUA 0.2 ml TUA 50 cm TUA 1, Kirk-Smith, et al

12 CS-US CS CS/US CS/US 1 2 POMS 3 1, 2 2 Figure 3 1 CS-US s- IgA p.05 CS CS /US CS-US 1 s-iga 1, 2 TUA s-iga 2 CS-US Figure 3 s-iga

13 s-iga p.05cs-us CS/US CS CS/US 2 s-iga CS-US 2 s-iga POMS 2 CS-US A-H D C T-A CS- US 2 CS-US s-iga 2 2 POMS TUA CS-US CS/US TUA CS

14 7 Ader & Cohen 1975 US US s-iga s-iga

15 8 e.g., Buske-Kirschbaum et al., 1994 ; Ghanta, Hiramoto, Solvason, Soong, & Hiramoto, 1990 ; Halley, 1991 References Ader, R., & Cohen, N Behaviorally conditioned immunosuppression. Psychosomatic Medicine, 37, Ader, R., & Cohen, N Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus. Science, 215, Ader, R., & Cohen, N CNS-immune system interactions : Conditioning phenomena. Behavioral and Brain Science, 8, Ader, R., & Cohen, N Conditioned responses are indeed conditioned. Behavioral and Brain Science, 9, Ader, R., & Cohen, N Psychoneuroimmunology : Conditioning and stress. Annual Review of Psychology, 44, Ader, R., Felten, D. L., & Cohen, N Psychoneuroimmunology 3rd ed New York, Academic Press. Ader, R., Felten, D., & Cohen, N Interactions between the brain and the immune system. Annual Review of Pharmacology and Toxicology, 30, Alvarez-Borda, B., Ramirez-Amaya, V., Perez-Montfort, R., & Bermudez-Rattoni, F Enhancement of antibody production by a learning paradigm. Neurobiology of Learning and Memory, 64,

Behavioral and Brain Science, 8, 379 394. Ader, R., & Cohen, N. 1986 Conditioned responses are indeed conditioned. Behavioral and Brain Science, 9, 760 763. Ader, R., & Cohen, N. 1993 Psychoneuroimmunology : Conditioning and stress.

16 Apanius, V Stress and immune defense. Advances in the study of behavior, 27, Baron, R. S., Cutrona, C. E., Hicklin, D., Russel, D. W. & Lubaroff, D. M Social support and immune function among spouses of cancer patients. Journal of Personality and Social Psychology, 59, Buske-Kirschbaum, A., Kirschbaum, C., Stierle, H., Jabaij, L., & Hellhammer, D Conditioned manipulation of natural killer NK cells in humans using a discriminative learning protocol. Biological Psychology, 38, Caudell, K. A., & Gallucci, B. B Neuroendocrine and immunological responses of women to stress. Western Journal of Nursing Research, 17, Calabrese, J. R., Kling, M. A., & Gold, P. W Alterrations in immunocompetence during stress, bereavement, and depression : Focus on neuroendocrine regulation. American Journal of Psychiatry, 144, Dalahanty, D. L., Dougall, A. L., Schmitz, J. B., Hawken, L., Trakowski, J. H., Jenkins, F. J., & Baum, A Time course of natural killer cell activity and lymphocyte poliferation in response to two acute stressors in healthy men. Health Psychology, 15, Dunn, A. J Psychoneuroimmunology for the psychoneuroendrocrinologist : A review of animal studies of nervous system-immune system interaction. Psychoneuroendrocrinology, 14, Ghanta, V. K., Hiramoto, R. N., Solvason, H. B., Soong, S-J., & Hiramoto, R. N Conditioning : A new approach to immunotherapy. Cancer Research, 50, Gorczynski, R. M Conditioned enhancement of skin allografts in mice. Brain, Behavior, and Immunity, 4, Graham, N. M. H., Bartholomeusz, R. C. A., Taboonpong, N. & LaBrooy, J. T Does anxiety reduce the secretion rate of secretory IgA in saliva? Medical Journal of Australia, 148, Halley, F. M Self-Regulation of the immune system through biobehavioral strategies. Biofeedback and Self-Regulation, 16, Herbert, T. B., & Cohen, S Stress and immunity in humans : a metaanalytic review. Psychosomatic Medicine, 55, Jemmot, J. B. 3 rd. & Locke, S. E Psychosocial factors, immunologic media-

, & Hellhammer, D. 1994 Conditioned manipulation of natural killer NK cells in humans using a discriminative learning protocol. Biological Psychology, 38, 143 155. Caudell, K. A., & Gallucci, B. B. 1995 Neuroendocrine and immunological responses of women to stress.

17 tion, and human susceptibility to infectious disease : How much do we know? Psychological Bulletin, 95, Jemmot, J. B. 3 rd. & Magloire, K Academic stress, social support, and secretory immunoglobulin A. Journal of Personality and Social Psychology, 55, Kelley, K. W., & Dantzer, R Is conditioned immunosuppression truly conditioned? Behavioral and Brain Science, 9, Kelley, K. W., Dantzer, R., Mormede, P., Salmon, H., & Aynaud, J. M Conditioned taste aversion suppresses induction of delayed-type hypersensitivity immune reactions. Physiology and Behavior, 34, Kirk-Smith, M. D., Van Toller, C., & Dodd, G. H Unconscious odour conditioning in human subjects. Biological Psychology, 17, Krank, M. D., & MacQueen, G Conditioned compensatory responses elicited by environmental signals for cyclophosphamide-induced suppression of the immune system. Psychobiology, 16, Kvale, D., & Brandtzaeg, P An enzyme-linked immunosorbent assay for differential quantitation of secretory immunoglobulins of the A and M isotypes in human serum. Journal of Immunological Methods, 86, s-iga Landmann, R. M. A., Muller, F. B., Perini, C. H., Wesp, M., Erna, P., & Buhler, F. R Changes of immunoregulatory cells induced by psychological and physical stress : Relationship to plasma catecholamines. Clinical and Experimental Immunology, 58, MacQueen, G. M., Marshall, J., Perdue, M., Siegel, S., & Bienenstock, J Pavlovian conditional of rat mucosal mast cells to secrete rat mast cell protease II. Science, 243, MacQueen, G. M. & Siegel, S Conditional immunomodulation following training with cyclophosphamide. Behavioral Neuroscience, 103, Matthews, K. A., Caggiula, A. R., McAllister, C. G., Berga, S. L., Owens, J. F., Flory, J. D., & Miller, A. L Sympathetic reactivity to acute stress and immune response in women. Psychosomatic Medicine, 57, McNaire, D. M., Lorr, M., & Droppleman, L. F Profile of Mood States. San Diego : Educational and industrial testing service. Mills, P. J., Dimsdale, J. E., Nelesen, R. A., & Dillon, E Psychologic charac-

1986 Is conditioned immunosuppression truly conditioned? Behavioral and Brain Science, 9, 758 760. Kelley, K. W., Dantzer, R., Mo

18 teristics associated with acute stressor-induced leukocyte subset redistribution. Journal of Psychosomatic Research, 40, Naliboff, B. D., Benton, D., Solomon, G. F., Morley, J. E., Fahey, J. L., Bloom, E. T., Makinodan, T., & Gilmore, S. L Immunological changes in young and old adults during brief laboratory stress. Psychosomatic Medicine, 53, S , Ohira, H., Watanabe, Y., Kobayashi, K., & Kawai, M The type A behavior pattern and immune reactivity to brief stress : change of volume of secretory immunoglobulin A in saliva. Perceptual and Motor Skills, 89, O Leary, A Stress, emotion, and human immune function. Psychological Bulletin, 108, O Reilly, C. A., & Exon, J. H Cyclophosphamide-conditioned suppression of the natural killer cell response in rats. Physiology and Behavior, 37, Pike, J. L., Smith, T. L., Hauger, R. L., Nicassio, P. M., Patterson, T. L., & McClintick, C Chronic life stress alters sympathetic, neuroendocrine, and immune responsitivity to an acute psychological stressor in humans. Psychosomatic Medicine, 59, Rogers, M. P., Reich, P., Strom, T. B., & Carpenter, C. B Behaviorally conditioned immunosuppression : Replication of a recent study. Animal Learning and Behavior, 12, Sieber, W. J., Rodin, J., Larson, L,. Ortega, S., & Cummings, N Modulation of human natural killer cell activity by exposure to uncontrollable stress. Brain, Behavior, and Immunity, 6, Smith, G. R., Jr., & McDaniel, S. M Psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans. Psychosomatic Medicine, 45, Solvason, H. B., Ghanta, V. K., & Hiramoto, R. N Conditioned augmentation of natural killer cell activity : Independence from nociceptive effects and dependence on interferon-beta. Journal of Immunology, 15, Solvason, H. B., Ghanta, V. K., Lorden, J. F., Soong, S. J. & Hiramoto, R. N A behavioral augmentation of natural immunity : Odor specificity sup-

Ohira, H., Watanabe, Y., Kobayashi, K., & Kawai, M. 1999 The type A behavior pattern and immune reactivity to brief stress : change of volume of secretory immunoglobulin A in saliva.

19 ports a Pavlovian conditioning model. International Journal of Neuroscience, 61, , Wayner, E. A., Flannery, G. R., & Singer, G The effects of taste aversion conditioning on the primary antibody response to sheep red blood cells and brucella abortus in the albino rat. Physiological Behavior, 21, IgA 1, POMS

1978 The effects of taste aversion conditioning on the primary antibody response to sheep

04-p45-67cs5.indd

04-p45-67cs5.indd Journal of Sport and Exercise Psychology Motivation in sport and exercise. Journal of Sport and Exercise Psychology Journal of Applied Sport Psychology Psychological Review International Journal of Behavioral