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1

2 Contents

3 1. growth hormone deficiency : GHD10,00015,000 2

4 GH T3T4 1 GHRHGHIH -CIGF-1 -CIGF-1 3

5 1 GHRH GHIH GH TSH LHFSH -C IGF-1 -C IGF-1 T3T4 4

6 23 8 5

7

8 3. 1 SD2 1. 2SD SD2 1 2SD SD1 22SD 7

9 Suwa, S et al : Clin Pediatr Endocrinol 1992, 11, cm -2SD cm cm -2SD cm -2.5SD cm -2.5SD cm -1.5SD cm/ -1.5SD cm/

10 cm 2SD 9

11 X X -C 10

12 MRICT %

13 L-DOPA L-DOPA ng/mL 12

14 ng/mL ng/mL 3. 5ng/mL ng/ml SD 11.5SD ng/mL 13

15

16

17 16

18 cm1 12.0cm 2.0cm 2.0cm 1.8cm 1.4cm 1.2cm 1.0cm

19 2.5SD 1 6.0cm 2.0cm 2 3cm 156.4cm145.4cm 18

20 TEL/FAX TEL/FAX TEL/FAX TEL/FAX

21 TEL/FAX

22 9. X

23

24 Copyright c 2008 Merck Serono Co., Ltd. All rights reserved. Reproduction in whole or in part without permission is prohibited.

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