加藤茂孝先生
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1 Shigetaka KATOW WHO TV WHO modern_media@eiken.co.jp RIKEN Center of Research Network for Infectious Diseases (Jimbocho 101 Bldg. 8th fl Kandajimbo-cho, Chiyoda-ku, Tokyo)
2 WHO 6 influenza influence in flow Smith, W. et al.: A virus obtained from influenza patient. Lancet, J. Natl. Inst. Public Health 3,
3 BC Thuchydides 1985 Langmuir 4 2 BC Langmuir, A.D. et al.: The Thuchydides Syndrome. New Eng J Med, 3131, Fields Virology. 5 th ed. D.M. Knipe et al. ed., Lippincott, Williams and Wilkins
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5 R.Pfeiffer Haemophilus influenzae B Hib B B
6 2008 Hib AIDS HIV V B Hib HIV 1933 Smith W 1 A A B 1940 Francis T C 1949 Taylor RM A, B, C A 2 1 HAHemagglutinin 16 1 NANeuraminidase 9 HA NA = HA NA H1N1 H5N1 B B HA 1 NA 1 HA Victoria 2 A H1 H2 C N A B C A 1 RNA 8 1 RNA DNA DNA RNA A
7 A RNA 8 4 RNA A H3N H1N1 H2N2 H3N H1N1 A 20 H1N1 H2N2 H3N21977 A 1 H1N A A AH1N1 A 2 1 2WHO AH3 AH1 BAH3 AH1 B , Beveridge W.I, B.: Influenza : The last great plague. London, Heinenmann
8 H1N H1N A H5N WHO H5N1 H5N H5N1 Cumulative Number of Confirmed Human Cases of Avian Influenza AH5N1Reported to WHO 9 December 2010http:
9 H5N HA H5 H7 1 HA HA H5N H5N1 8 H5N1 4 4 H5 4 International Epizootic OfficeOIE 5, Shinya, K., M. Ebina, S. Yamada, M. Ono, N. Kasai, and Y. Kawaoka. Avian flu : influenza virus receptors in the human airway. Nature :
10 H1N RNA 3 5, i 1933 ii iii A B 2009 iv v 1 80
11 ,000 5,000 1 F Alfred W. Crosby, 2004
12 WHO H1N PCR 14 Teiichiro Shiino et al.: Molecular Evolutionary Analysis of the Influenza AH1N1pdm, May-September, 2009 : Temporal and Spatial Spreading Profile of the Viruses in Japan. 56, e11057, June2010
13 A H1N1A H3N2 B A H1N1 H1N1 3 WHO RNA RNA P. Palese M Enami and P Palese : High-efficiency formation of influenza virus transfectants. J Virol. 5: Neumann, G. et al. Generation of influenza A viruses entirely from cloned cdnas. Proc Natl Acad Sci USA :
14 2009 2,
15 5 ACIP Advisory Committee for Immunization Practices all Japan CDC SARS CDC J.L.Gerberding B CDC
16 CDC Julie Louise Gerberding ACIP 17 GDP R.E. Neustadt, H. V. Fineberg
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