第17回環境イオ学研究所・第11回研究推進委員会合同セミナー特別講演

Size: px
Start display at page:

Download "第17回環境イオ学研究所・第11回研究推進委員会合同セミナー特別講演"

Transcription

1 Worcester Marshall Medal 1998 Distinguished Andrologist Award 1999 Carl G. Hartman Award 2000 Pioneer Award

2 µm cell 4-cell 3 1 2

3 E.B.Wilson Cell in Development and Heredity 6 germ cell germ cell 6 germ cell germ cell 7 7 germ cell A. Weismann 3

4 8 germ cell Weismann 9 germ cell germ cell germ-cell Germ cell 11 4

5 Rhizocephala) 12 germ cell 1 1 Austin 5

6 Chang Thibault 3 Ph.D. M.C. Chang Chang Ph.D. Ph.D. postdoctral fellow 2 1 post doc Dr. Chang "Well You did a good work with fish." Dr. Chang Cambridge (Ph.D.) Cambridge 15 Chang

7 Worcester Foundation Chang New England Dr. Chang Dr. Chang Dr. M.C. Chang Foundation 1 Yanagimachi Ryuzo Ryu Dr. Chang "Yana" "OK" Yana Dr. Chang "Yana, There are 5 working days a week. You must use 3 days for this project. remaining 2 days for what you want to do." You may use the 7

8 3 bread & butter 2 3 Dr. Chang 4 16 Dr. Chang "Ask a simple, important question" 17 In vitro fertilization IVF: 2 Edwards IVF IVF

9 µm Dr. Chang Dr. Austin 1952 "capacitation" capacitation in vitro capacitation in vitro Nature Nature Dr. Chang 20 IVF Edwards in vitro capacitation encourage 21 (30 Dr. M.C. Chang Dr. Pincus 60 Dr. Pincus Harvard " " Harvard Worcester Foundation Chang

10 Dr. Pincus (Ph.D.) Dr. Rock (M.D.) Ph.D. M.D. IVF Ph.D. (Dr. Edwards). M.D. (Dr. Steptoe) Ph.D. M.D. 1+1=2 3 4 Dr. Chang 22 4 Dr. Chang Dr. Pincus Dr. Chang Dr. Pincus 1 22 "Yana " postdoctral fellow Lalor Foundation Vanderbilt Dr. Noyes IVF medical school

11 Hawaii Medical School Capacitation 26 capacitation

12 "workaholic" 40 essence Happy face Happy face 2n capacitation 29 12

13 C "Yana " (intra- cytoplasmic sperm injection: ICSI)

14 (ICSI) 33 IVF ICSI ICSI IVF IVF ICSI IVF IVF ICSI ICSI assisted fertilization 1997 Dolly Dolly -cell 4-cell Dolly Dolly Dolly Wilmut 2 14

15 Dolly 6 Science review "This is not a subject of generally interest." Nature Nature editor 3 OK 3 3 Mentor 35 15

16

17 excellent 17

18 "very boring" Nature accept 18

19 "so what!?" "Give and take" 41 "Yana " Native 19

20 2006 ES Dr. Hwang ( ) National Academy of Sciences "My beautiful wife " "My stupid wife" cooking authorship 10 PNAS ( accept 20

21 #42 Dr. Hwang NIH grant NIH NIH NIH grant 44 Study Section Reproductive Biology Section NIH grant grant 1 3 grant Primary (Principle) reviewer Secondary reviewer Discussant Study Section NIH /2 Study Section 43 21

22 1 NIH Study Section 45 NIH grant D.C. Study Section 46 22

23 Ph.D. M.D. 1/ A grant 3 Chairman A propose Nepotism chairman 3 23

24 chairman "Vote" NIH 5 3 NIH 1.0 grant grant grant grant grant grant 48 important question " " 48 " 24

25 " NIH "Asking an important question?" important question 7 NIH 49 "Clear vision" 49 grant grant NIH Study Section 25

26 NIH

0 Speedy & Simple Kenji, Yoshio, and Goro are good at English. They have their ways of learning. Kenji often listens to English songs and tries to remember all the words. Yoshio reads one English book every

More information

†ı25”Y„o-PDF.ren

†ı25”Y„o-PDF.ren 12,000 10,000 8,000 6,000 4,000 2,000 0 1998 1999 2000 2001 2002 2003 2004 1,200 1,000 800 600 400 200 0 1998 1999 2000 2001 2002 2003 2004 $ "! ''" '' ''$ ''% ''& '''! " ' & % $ "! ''" ' '$ '% '& ''!

More information

76

76 ! # % & % & %& %& " $ 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 % & &! & $ & " & $ & # & ' 91 92 $ % $'%! %(% " %(% # &)% & 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 !$!$ "% "%

More information

IN137718TY.indd

IN137718TY.indd 2007-2008 2007-2008 SHIGA UNIVERSITY OF MEDICAL SCIENCE ACTIVITY DIGEST % " # $ % & & '! 1 2 3 4 5 95% 98% 95% 96.4% 100% 92.6% 89.1% 91.4% 81.5% 91.8% 93.2% 91.7% 90.0% 88.3% 78.1% 97.1% 98.4% 100% 100%

More information

4 2 1 2 61 280 351 The Way We Are5 1 1 2 3 no.51 20017 2 2276 35 5 5 TJF 5 5 TJF

4 2 1 2 61 280 351 The Way We Are5 1 1 2 3 no.51 20017 2 2276 35 5 5 TJF 5 5 TJF ISSN 0919-7265 2001 7 no.51 TJF 4 2002!3 p.8!3 p.10 i p.16 TJF p.12 2001456 TJF p.15 4 2 1 2 61 280 351 The Way We Are5 1 1 2 3 no.51 20017 2 2276 35 5 5 TJF 5 5 TJF no.51 20017 3221 52 TJF NETNative English

More information

;; ; ;; ;;; ; ;; ;; ;; ; ;; ; ;; ; ;;;; ;; ;;;;;;; ;;;;;;;; ;;;;;;;;; ;;;;;;; ;;;;;;; ;;;;;;; ;;;;;;;; Harvard

More information

資料4:家族形成のための生殖医療(石原委員資料)

資料4:家族形成のための生殖医療(石原委員資料) 資料 4 ICMART (Interna.onal Commi3ee Monitoring ART) IFFS (Interna.onal Federa.on of Fer.lity Socie.es) 30/10/18 2009Infer.lity (clinical defini.on): a disease of the reproduc.ve system defined by the failure

More information

篇 S-V / S-V-C / S-V-O / S-V-O-O / S-V-O-C IA 25 Mike Lawson 1 1 Students will improve their ability to use English in a professionally relevant manner by practicing a process of speech outline

More information

紀要1444_大扉&目次_初.indd

紀要1444_大扉&目次_初.indd 1. Hi, How are you? / What s up? / How s it going? A / Nice talking to you. 2. Oh really? / That s great! / That s A, B interesting! / Are you serious? / Sounds good. / You too! / That s too bad. 3. Sorry?

More information

”Y‰Æ”ЛïŸ_‘W40−ª3/ ‰{fic

”Y‰Æ”ЛïŸ_‘W40−ª3/ ‰{fic Assisted Reproductive Technology ART ART In Vitro Fertilization- Embryo Transfer IVF-ET,ART, ART ART ART IVF-ET IVF-ET IVF-ET IVF-ET IVF-ET ART ART ART IVF- ET, ART ART IVF-ET ART Ovarian Hyper Stimulation

More information

IF_SUPRECUR_N29

IF_SUPRECUR_N29 ! @ # $ % ^ & * ( ) _ + )# ! a s d a s d f g h a s d @ a s d a s # a s d f g h j $ a s d f g h a s d % a s a a s a s a s d f g ^ a s a s a s & a s d f a s d f g h a s d f g a s d f g a s d a s d * s

More information

! " # $ % & ' ( ) +, -. / 0 1 2 3 4 5 6 7 8 9 : ; < = >? @ A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [ ] ^ _ ` a b c d e f h i j k l m n o p q r s t u v w x y z { } ~ This product is

More information

Juntendo Medical Journal

Juntendo Medical Journal * Department of Health Science Health Sociology Section, Juntendo University School of Health and Sports Science, Chiba, Japan (WHO: Ottawa Charter for Health promotion, 1986.) (WHO: Bangkok Charter

More information

10 2000 11 11 48 ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) ( ) CU-SeeMe NetMeeting Phoenix mini SeeMe Integrated Services Digital Network 64kbps 16kbps 128kbps 384kbps

More information

untitled

untitled -1- -2- -3- -4- -5- OPERATION 44.4% 20.4% 14.8% 20.4% RECEIVING OPERATION CALLING OTHERS -6- (Evaluation) (Synthesis) (Analysis) (Application) (Comprehension) (Knowledge) -7- Level 3 Level 2 Level 1 Level

More information

財政金融統計月報第720号

財政金融統計月報第720号 ! # " $ % &! # % " $ &! # % " $ &! # %! # % " $ & " $ &! # % " $ & !!!!!!! !!!!!!! ! # " $ ! # " $ ! " # $! " # $ ! # " $ ! # $& %" !

More information

[2] 1. 2. 2 2. 1, [3] 2. 2 [4] 2. 3 BABOK BABOK(Business Analysis Body of Knowledge) BABOK IIBA(International Institute of Business Analysis) BABOK 7

[2] 1. 2. 2 2. 1, [3] 2. 2 [4] 2. 3 BABOK BABOK(Business Analysis Body of Knowledge) BABOK IIBA(International Institute of Business Analysis) BABOK 7 32 (2015 ) [2] Projects of the short term increase at present. In order to let projects complete without rework and delays, it is important that request for proposals (RFP) are written by reflecting precisely

More information

S1460...........\1.E4

S1460...........\1.E4 3 4 3 4 5 3 4 5 3 4 3 4 3 3 3 3 4 3 4 3 3 4 4 3 3 3 3 4 3 4 3 3 3 3 3 3 4 3 4 3 4 5 4 3 5 4 3 3 4 5 3 4 5 4 3 4 3 3 4 3 4 3 3 3 3 3 4 3 3 4! "! " " 0 6 ! " 3 4 3 3 4 3 ! " 3 3 4 5 4 5 6 3 3

More information

-----------------------------------------------------------------------------------------1 --------------------------------------------------------------------------------------1 -------------------------------------------------------------------------------------1

More information

›¼’à”v“lŠÍ1−ª

›¼’à”v“lŠÍ1−ª 3 1 1 2 3 4 5 6 7 8 8 10 12 14 16 18 20 22 24 2 1 2 3 4 5 6 7 8 9 10 11 12 26 28 30 32 34 36 38 40 42 44 46 48 50 4 3 1 2 3 4 5 52 54 56 58 60 6 62 7 8 9 10 64 66 68 70 72 5 1 1 4 2 5 6 6 7 1 8 1 9 2 10

More information

1 2 3 4 1 2 3 4 1 2 3 4 12 3 4

1 2 3 4 1 2 3 4 1 2 3 4 12 3 4 1 2 3 4 5 6 1 2 3 4 5 6 1 2 1 2 1 2 1 2 1 2 3 4 12 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 12 3 4 1 2 3 4 5 6 7 8 1 2 3 46 7 1 2 3 4 5 6 7 1 2 3 4 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 16 7 8 92 3 46 7 :

More information

- 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10 - 11 2-12 - 1 - 2 - 3 - 4 - 5 - 6 - 7 - 1 - 2 - 3 6 1 1-4 - 5 - 6 - 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 130 3 130 5 2 50 1.5 48 59 62 63-9 - 1 - 2 - 3 () - 4 - 5 -

More information

C 1) 2) 3) 4) 5) 6) 7) 8) 9)

C 1) 2) 3) 4) 5) 6) 7) 8) 9) 130603 (1-3) C 1) 2) 3) 4) 5) 6) 7) 8) 9) C 1) 2) 3) DNA 4) DNA RNA 5) 6) PCR 7) DNA C Cyclops Odlilon Redon, The Cyclops, 1914 WAGR www.wagr.org WAGR www.wagr.org Cell 126, 663-676, 2006 Wikipedia

More information

<95AA8E718CA4838C835E815B835937308D862E696E6464>

<95AA8E718CA4838C835E815B835937308D862E696E6464> 8 70 September 2014 Inokuchi sensei played an outstandingly important role in scientific and research relations between Japan and the UK in the important area of the Molecular Sciences, often when linked

More information

[109-126]藤原武男

[109-126]藤原武男 - - Humane Vitae human individual human person individual person p individual person individual human person.. active brain Mayo Clinic Takeo Fujiwara In order to discuss the concept of the beginning

More information

07_高平小百合.indd

07_高平小百合.indd 2014 pp. 103 125 13 2 4 2 T 2 24 10 3 2012 61 2 1997 2004 2008 2015 2 17 103 2014 20132000 2009 2011 2011 2013 2013 1997 90 20 3 5 10 50 2013 2007 2009 2008 2009 2011 2009 5 2008 4 2008 2010 2011 104 2

More information

An Empirical Study on Media Frames: How the Newspapers Covered "All Five Walks" in the Summer High School Baseball Tournament in 1992. IBARAGI Yoshiko Recently the role of "media frames" in the process

More information

Title 社 会 化 教 育 における 公 民 的 資 質 : 法 教 育 における 憲 法 的 価 値 原 理 ( fulltext ) Author(s) 中 平, 一 義 Citation 学 校 教 育 学 研 究 論 集 (21): 113-126 Issue Date 2010-03 URL http://hdl.handle.net/2309/107543 Publisher 東 京

More information

1 48

1 48 Section 2 1 48 Section 2 49 50 1 51 Section 2 1 52 Section 2 1 53 1 2 54 Section 2 3 55 1 4 56 Section 2 5 57 58 2 59 Section 2 60 2 61 Section 2 62 2 63 Section 2 3 64 Section 2 6.72 9.01 5.14 7.41 5.93

More information

Section 1 Section 2 Section 3 Section 4 Section 1 Section 3 Section 2 4 5 Section 1 6 7 Section 1 8 9 10 Section 1 11 12 Section 2 13 Section 2 14 Section 2 15 Section 2 16 Section 2 Section 2 17 18 Section

More information

2 3 4 5 6 7 8 9 10 11 Licca is always with you 12 13 14 16 17 18 19 20 21 22 23 24 25 26 27 28 30 30 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31 31

More information

●70974_100_AC009160_KAPヘ<3099>ーシス自動車約款(11.10).indb

●70974_100_AC009160_KAPヘ<3099>ーシス自動車約款(11.10).indb " # $ % & ' ( ) * +, -. / 0 1 2 3 4 5 6 7 8 9 : ; < = >? @ A B C D E F G H I J K L M N O P Q R S T U V W X Y " # $ % & ' ( ) * + , -. / 0 1 2 3 4 5 6 7 8 9 : ; < = > ? @ A B

More information

005 1571 1630 17 1546 1601 16 1642 1727

005 1571 1630 17 1546 1601 16 1642 1727 I Takamitsu Sawa / 1561~1626 004 2010 / No.384 005 1571 1630 17 1546 1601 16 1642 1727 006 2010 / No.384 confirm refute verify significant 1902 1994 piecemeal engineering 1958 historicism 20 007 1990 90

More information

橡100ninnokoe

橡100ninnokoe Question 1 Question 2 Question 3 Question 4 Question 5 Question 6 Question 7 Question 8 Question 1 Question 2 Question 3 Question 2 Question 1 Question 3 Question 5 Question 4 Question 6 Question 7

More information

1 Question 1

1 Question 1 1 Question 1 2 2 Question 3 3 Question 4 4 Question 5 5 Question 6 6 Question 7 Question 8 8 Question 9 9 Question 10 10 Question 11 11 Question 12 12 Question 13 13 Question 14 14 Question 15 15 Question

More information

Mike Lawson Basing class activities on various cross-cultural themes, the objective of this course is to improve students practical levels of reading and listening comprehension and their abilities to

More information

医学教育研究とは 2011_10_14 v1

医学教育研究とは 2011_10_14 v1 - - how to overview - overview - - - - - Harden RM (1986). Medical Education, 20: 522-531 PBL Description: What was done? 64% Justification: Did it work? 29% Clarification: Why or how did it work 7% Cook

More information

DEIM Forum 2009 E

DEIM Forum 2009 E DEIM Forum 2009 E5-3 464-8601 1 606-8501 464 8601 1 E-mail: lifushi@arch.itc.nagoya-u.ac.jp, mayumi@mm.media.kyoto-u.ac.jp, {hirano,kajita,mase}@itc.nagoya-u.ac.jp Abstract Study on a Recipe Recommendation

More information

2013 Vol.1 Spring 2013 Vol.1 SPRING 03-3208-2248 C O N T E N T S 2013 03-3208-2248 2 3 4 7 Information 6 8 9 11 10 73 94 11 32 37 41 96 98 100 101 103 55 72 1 2 201345135016151330 3 1 2 URL: http://www.wul.waseda.ac.jp/clib/tel.03-3203-5581

More information

untitled

untitled Show & Tell Presentation - 170 - Presentation 1) Choose 1 topic 2) Write the reasons why you chose the topic. 3) Think about 3 points for the topic. Class No Name What would you like to do after graduation?

More information

P

P 03-3208-22482013 Vol.2 Summer & Autumn 2013 Vol.2 Summer & Autumn 90 527 P.156 611 91 C O N T E N T S 2013 03-3208-2248 2 3 4 6 Information 7 8 9 10 2 115 154 10 43 52 61 156 158 160 161 163 79 114 1 2

More information

- 1 - - 2 - 10.8 24.9 24.6 28.1 38.1 43.8-3 - - 4 - - 5 - - 6 - - 7 - - 8 - 2 3-9 - - 10 - - 11 - - 12 - - 13 - - 14 - - 15 - - 16 - - 17 - - 18 - - 19 - - 20 - - 21 - - 22 - - 23 - - 24 - - 25 - - 26

More information

untitled

untitled Four Corners Game ALT ALT spring, summer, autumn, winter When is your birthday? Which season do you like? Which season do you like? Which season do you eat this? Merry Christmas! present,snowman,two/threeballs

More information

MC-440 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67

More information

-2-

-2- Unit Children of the World NEW HORIZON English Course 'Have you been to?' 'What have you done as a housework?' -1- -2- Study Tour to Bangladesh p26 P26-3- Example: I am going to Bangladesh this spring.

More information

108 528 612 P.156 109

108 528 612 P.156 109 2012 Vol.2 Summer & Autumn 03-3208-2248 108 528 612 P.156 109 C O N T E N T S 2012 03-3208-2248 2 3 4 6 Information 7 8 9 2 114 154 156 158 160 161 163 9 43 52 61 79 113 1 2 2012 7 1 2 3 4 5 6 7 8 9 10

More information

:- Ofer Feldman,Feldman : -

:- Ofer Feldman,Feldman : - - -- E-mail: nkawano@hiroshima-u.ac.jp : - :- Ofer Feldman,Feldman : - : : : Mueller : - Mueller :.. : ... :........ .. : : : - : Kawano & Matsuo: - : - : - : : No. Feldman, Ofer (), The Political

More information

*MJ-S100B

*MJ-S100B MJ-S100B This appliance is designed for domestic use in Japan only and cannot be used in any other country. No servicing is available outside of Japan. !! &' $ $ $ & ' ' %! ! # "!! $ ' !! # ! "!! ! '

More information

*MJ-H100DX

*MJ-H100DX MJ-H100DX This appliance is designed for domestic use in Japan only and cannot be used in any other country. No servicing is available outside of Japan. ' ' $ % $ % & &' & "#!! ! "#! ' # $% " "# ' &! '

More information

動 作 動 詞 の have 食 べる 受 ける なら 現 在 進 行 形 になれる d We are having lunch in the classroom. [ 和 訳 ]( 私 たちは 今 教 室 で 昼 食 を 食 べている[ところだ]) e He is having the math

動 作 動 詞 の have 食 べる 受 ける なら 現 在 進 行 形 になれる d We are having lunch in the classroom. [ 和 訳 ]( 私 たちは 今 教 室 で 昼 食 を 食 べている[ところだ]) e He is having the math 1-25 現 在 進 行 形 (1) ~しているところだ が 現 在 進 行 形 be 動 詞 am, are, is と 現 在 分 詞 のセット 現 在 進 行 形 は 主 語 に 合 った 現 在 形 の be 動 詞 (am are is)と 現 在 分 詞 (ing 形 )をセットで 使 う 和 訳 は 現 在 進 行 形 なら ~している ~しているところだ ~しつつある にし 動 かす

More information

…O…›…fi…V…b…v›ï‘ê.Qx

…O…›…fi…V…b…v›ï‘ê.Qx 900 915 90 945 1000 1015 100 1045 1100 1115 110 1145 1,2 2 2 1 2 Department of Anatomy and Histology, University of Sydeney 1 2 1 2 2 1 1 1 2 NIDCR, NIH, USA 1 1 2 2 2 1 1 2 NIDCRNIHUSA 1 2 1 1 University

More information

MJ-H100BX

MJ-H100BX MJ-H100BX This appliance is designed for domestic use in Japan only and cannot be used in any other country. No servicing is available outside of Japan. ' $ % $ % $ &'! %! %! ! &! " ' # "# $ $ ! $ ' $

More information

Professor of Epidemiology and Nutrition, Harvard School of Public Health Personal History 1945 Born in Hart, Michigan, USA 1970 M.D. University of Mic

Professor of Epidemiology and Nutrition, Harvard School of Public Health Personal History 1945 Born in Hart, Michigan, USA 1970 M.D. University of Mic The Search for Optimal Diets: A Progress Report Commemorative Lecture at the Twenty-Fifth Honda Prize Awarding Ceremony on the 17th November 2004 in Tokyo Walter C. Willett Professor of Epidemiology and

More information

2002 31 3 4 5 6 10 12 15 1 18 19 20 1

2002 31 3 4 5 6 10 12 15 1 18 19 20 1 2002 31 3 4 5 6 10 12 15 1 18 19 20 1 2002 31 2 21 NATO 22 NATO 23 1 24 25 26 27 2 Soviet Industrial Location: A Reexamination 28 29 Department of History and Classics, University of Alberta 30 31 2 2002

More information

1986 NHK 2000 2004 NTT NTT CONTENTS 01 03 05 07 09 11 4 1 13 2 14 34 15 17 19 21 SNS 1 4 12 34 4 23 25 1 26 27 29 01 School of Information and Communi

1986 NHK 2000 2004 NTT NTT CONTENTS 01 03 05 07 09 11 4 1 13 2 14 34 15 17 19 21 SNS 1 4 12 34 4 23 25 1 26 27 29 01 School of Information and Communi 1986 NHK 2000 2004 NTT NTT CONTENTS 01 03 05 07 09 11 4 1 13 2 14 34 15 17 19 21 SNS 1 4 12 34 4 23 25 1 26 27 29 01 School of Information and Communication 02 Point 1 P.1112 2011 Point 2 P.1316 Point

More information

鹿大広報149号

鹿大広報149号 No.149 Feb/1999 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Learned From Japanese Life and Experiences in Kagoshima When I first came to Japan I was really surprised by almost everything, the weather,

More information

専門力_総合力

専門力_総合力 Program for Leading Graduate Schools Program for Leading Graduate Schools INTRODUCTION 04 CONTENTS 10 15 23 24 30 32 33 34 36 38 39 DATA 40 42 44 Program for Leading Graduate Schools What is a DOCTOR??

More information