第17回環境イオ学研究所・第11回研究推進委員会合同セミナー特別講演
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- つかさ あきくぼ
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1 Worcester Marshall Medal 1998 Distinguished Andrologist Award 1999 Carl G. Hartman Award 2000 Pioneer Award
2 µm cell 4-cell 3 1 2
3 E.B.Wilson Cell in Development and Heredity 6 germ cell germ cell 6 germ cell germ cell 7 7 germ cell A. Weismann 3
4 8 germ cell Weismann 9 germ cell germ cell germ-cell Germ cell 11 4
5 Rhizocephala) 12 germ cell 1 1 Austin 5
6 Chang Thibault 3 Ph.D. M.C. Chang Chang Ph.D. Ph.D. postdoctral fellow 2 1 post doc Dr. Chang "Well You did a good work with fish." Dr. Chang Cambridge (Ph.D.) Cambridge 15 Chang
7 Worcester Foundation Chang New England Dr. Chang Dr. Chang Dr. M.C. Chang Foundation 1 Yanagimachi Ryuzo Ryu Dr. Chang "Yana" "OK" Yana Dr. Chang "Yana, There are 5 working days a week. You must use 3 days for this project. remaining 2 days for what you want to do." You may use the 7
8 3 bread & butter 2 3 Dr. Chang 4 16 Dr. Chang "Ask a simple, important question" 17 In vitro fertilization IVF: 2 Edwards IVF IVF
9 µm Dr. Chang Dr. Austin 1952 "capacitation" capacitation in vitro capacitation in vitro Nature Nature Dr. Chang 20 IVF Edwards in vitro capacitation encourage 21 (30 Dr. M.C. Chang Dr. Pincus 60 Dr. Pincus Harvard " " Harvard Worcester Foundation Chang
10 Dr. Pincus (Ph.D.) Dr. Rock (M.D.) Ph.D. M.D. IVF Ph.D. (Dr. Edwards). M.D. (Dr. Steptoe) Ph.D. M.D. 1+1=2 3 4 Dr. Chang 22 4 Dr. Chang Dr. Pincus Dr. Chang Dr. Pincus 1 22 "Yana " postdoctral fellow Lalor Foundation Vanderbilt Dr. Noyes IVF medical school
11 Hawaii Medical School Capacitation 26 capacitation
12 "workaholic" 40 essence Happy face Happy face 2n capacitation 29 12
13 C "Yana " (intra- cytoplasmic sperm injection: ICSI)
14 (ICSI) 33 IVF ICSI ICSI IVF IVF ICSI IVF IVF ICSI ICSI assisted fertilization 1997 Dolly Dolly -cell 4-cell Dolly Dolly Dolly Wilmut 2 14
15 Dolly 6 Science review "This is not a subject of generally interest." Nature Nature editor 3 OK 3 3 Mentor 35 15
16
17 excellent 17
18 "very boring" Nature accept 18
19 "so what!?" "Give and take" 41 "Yana " Native 19
20 2006 ES Dr. Hwang ( ) National Academy of Sciences "My beautiful wife " "My stupid wife" cooking authorship 10 PNAS ( accept 20
21 #42 Dr. Hwang NIH grant NIH NIH NIH grant 44 Study Section Reproductive Biology Section NIH grant grant 1 3 grant Primary (Principle) reviewer Secondary reviewer Discussant Study Section NIH /2 Study Section 43 21
22 1 NIH Study Section 45 NIH grant D.C. Study Section 46 22
23 Ph.D. M.D. 1/ A grant 3 Chairman A propose Nepotism chairman 3 23
24 chairman "Vote" NIH 5 3 NIH 1.0 grant grant grant grant grant grant 48 important question " " 48 " 24
25 " NIH "Asking an important question?" important question 7 NIH 49 "Clear vision" 49 grant grant NIH Study Section 25
26 NIH
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