|
|
- きみのしん いせき
- 7 years ago
- Views:
Transcription
1
2
3 or or
4
5 100, , , , , , , , ,
6
7
8
9 kg: 1g:
10 5 8 10
11
12 1 DNA
13 myc E1A myc E1A +ras ras myc E1A myc+ras E1A +ras ras
14
15
16
17
18 %
19
20
21 ml 1 1.4
22
23 (%) (Tobacco) 30 (Adult diet/obesity) 30 (Sedentary lifestyle) 5 (OccupaHonal factors) 5 (Family history of cancer) 5 (Viruses/other biologic agents) 5 (Perinatal factors/growth) 5 (ReproducHve factors) 3 (Alcohol) 3 (Socioeconomic status) 3 (Environmental polluhon) 2 (Ionizing/ultraviolet radiahon) 2 (PrescripHon drug/medical procedures) 1 (Salt/other food addihves/contaminants) 1 Harvard Center for Cancer Preven:on: Harvard Report on Cancer Preven:on, Volume 1: Causes of Human Cancer, Cancer Causes Control 1996 ;7:S3 S59.
24 N 3 / B2, B6, B12, C, D, E WHO technical report series 916. Diet, nutri:on and the preven:on of chronic diseases. WHO, Geneva, (2003)
25
26 BRCA1 D. D. 2
27 BRCA1 (mulhple endocrine neoplasia) MEN types 1, 2a, 2b p53 Li Fraumeni (Li Fraumeni syndrome) ( ) APC (Familial adenomatous polyposis) Rb
28 : 60% 40% (80% ) 10-20% 90% 60
29
30 95% 75 95% 95% (Environment and heritable factor in the causa:on of cohorts of twins from Sweden and Finland. N Eng J Med 343:78 85, 2000
31
32
33
34
35 肝転移と骨転移 肝転移 肝臓の両葉に白い結節状の転移巣が 多発している 肝不全になる 骨シンチにて脊椎および仙腸関節部に集積がある CTにて脊椎の溶骨を認め MRIにて脊椎に低信号 部を認める 脊椎の圧迫骨折や骨盤の骨折が起こ りやすい
36 stage 0 ( ) stage 1 ( ) stage 2 ( ) stage 3 ( ) stage 4 ( )
37
38
39
40
41 (%) (Tobacco) 30 (Adult diet/obesity) 30 (Sedentary lifestyle) 5 (OccupaHonal factors) 5 (Family history of cancer) 5 (Viruses/other biologic agents) 5 (Perinatal factors/growth) 5 (ReproducHve factors) 3 (Alcohol) 3 (Socioeconomic status) 3 (Environmental polluhon) 2 (Ionizing/ultraviolet radiahon) 2 (PrescripHon drug/medical procedures) 1 (Salt/other food addihves/contaminants) 1
42 N 3 / B2, B6, B12, C, D, E WHO technical report series 916. Diet, nutri:on and the preven:on of chronic diseases. WHO, Geneva, (2003)
43 g
44 1 2 BMI g [1 250ml 100ml 25ml ] 7 ( ) 1 80g g
45 500g
46 S 40 25
47 1990
48
49
50 X X X Randomize d Controlled Trial : RCT
51
52 (H. pylori) 490, (HPV) 550, (HBV, HCV) 90, (EBV) 99, (HHV 8) 54, , (HTLV 1) 2, (Liver flukes) 800 1,600, (1995 ) 9,000,
53 HP The Japan Gast Study Group
54 HP
55
56
57
58 Susceptible Intention-to-treat
59
60
23 3 11 14 46 9.0 7 10m 40.1m 15,883 2,681 25 4 10 39 40 800 180 24 2425 22 21 24 5 3 21 24 10,899 20,472 13,723 33,007 667 400 79,167 8,620 11,694 10,089 25,131 690 215 56,439 13,614 20,897 15,200 32,213
More information104 100 60 9,195,336 409 0.004 24 8 31 9,025,983 568 0.006 2012 8 31 6,634,686 956 ( 0.014 ) 2 2011 8 26
25 25 3 5 MMR 1 104 100 60 9,195,336 409 0.004 24 8 31 9,025,983 568 0.006 2012 8 31 6,634,686 956 ( 0.014 ) 2 2011 8 26 2012 8 31 1,032,660 132 ( 0.013 ) 3 2010 6 11 3 11 15.4 1 1 ( ) 12 2 2 3 ER ) (
More information環境報告書2015.indd
ENVIRONMENTAL and SOCIAL REPORT 2015 1 C O N T E N T S 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 1 2 4 5 6 7 8 14 18 20 22 24 25 28 29 2 1 37.1 62.9 2 3 1 4 2 5 6 3 1 4 1 2 7 8 8 5 1 9 2 10 10 2 11 2
More information小児感染免疫第23巻第1号
Vol. 23No. 163 42 HPV HPV 1113 HPV 42 HPV HPV HPV 1 1 510 1020 HPV 1020 510 HIV 0.1 0.005 HIV 2030 HIV 0.2 510 HPV 1020 15 HIV 2030 HIV HIV 0.2 0.1 Takeyuki Sato 2608677 181 64 2011 2 1 1518 6,000 513
More information- 1 - A B C D E or or D or or d - 2 - A p18 P19 P21-3 - - 4 - B 2001 P21 P18 P19-5 - - 6 - C P21-7 - - 8 - D P21-9 - P16-10 - E - 11 - RT-PCR - 12 - P16-13 - P21-14 - P16-15 - - 16 - - 17 - Yes No Yes
More information- 1 - 15 2030 4 21 21-2 - 2 1 21 21 4 22 31 10 5 26 ( JA ) - 3 - 4 21 7 9 9 34 1,386 1,003 94 58 1,155 60 25 33 1 3 2-4 - 12 17 60 7 7 12 H1217 4 7 30 34 19-5 - - 6 - (BMI*18.5) 20 15.2%30 8.% 20 86.4%30
More informationprogram_japanese
Eng Eng Eng - 40 - Eng Eng - 41 - Eng Eng - 42 - Eng - 43 - Eng - 44 - Eng Eng - 45 - Eng - 46 - - 47 - Eng - 48 - - 49 - - 50 - - 51 - - 52 - - 53 - - 54 - - 55 - - 56 - - 57 - - 58 - - 59 - - 60 - -
More information23 3 11 24 21 24 25 4 28 4 2 7 161 2,692 28 12 14 18 18 380 5 3 1 27 21 21 24 10,899 20,472 13,723 33,007 667 400 79,167 8,620 11,694 10,089 25,131 690 215 56,439 13,614 20,897 15,200 32,213 640 416 82,979
More informationHPV HPV HPV HPV 7 HPV 8 9 HPV 3 HPV HPV HPV , Becker Ajzen H
3 26 3 Journal of Junshin Gakuen University, HPV Faculty of Health Sciences Vol.3, March 2014 99 HPV Knowledge of and attitudes towards human papillomavirus vaccinations among mothers who have daughters
More information100% 6 1. ( ) 2. ( ) 3. () 11 12
(1) 1C24131 1.0 1 2 AB 1 1 ()3 120 C 100 (1) 1 2 3,, 1 4 14 2 4 21 3 4 28 4 5 12 5 5 19 6 5 26 7 6 2 8 6 9 9 6 16 10 6 23 11 6 30 3 100% 6 1. ( ) 2. ( ) 3. () 11 12 1 1C07011 1.0 1 2 AB 2,,,,, () 200 C
More informationuntitled
-- -- -3- % % % 6% % % 9 66 95 96 35 9 6 6 9 9 5 77 6 6 5 3 9 5 9 9 55 6 5 9 5 59 () 3 5 6 7 5 7 5 5 6 6 7 77 69 39 3 6 3 7 % % % 6% % % (: ) 6 65 79 7 3 36 33 9 9 5 6 7 3 5 3 -- 3 5 6 76 7 77 3 9 6 5
More informationuntitled
NO. 2007 10 10 34 10 10 0570-058-669 http://www.i-nouryoku.com/index.html (40 ) () 1 NO. 2007 10 10 2.2 2.2 130 70 20 80 30 () () 9 10 () 78 8 9 () 2 NO. 2007 10 10 4 7 3 NO. 2007 10 10 40 20 50 2 4 NO.
More informationuntitled
---------- - 1 - ----- 1 Q1 5 Q2 5 Q3 5 Q4 6 Q5 6 Q6 7 Q7 7 Q8 7 Q9 8 Q10 : 8 10 Q1 10 Q2 11 Q3 11 12 Q4 12 Q5 HBs HBc _12 Q6 HBe 12 Q7 13 Q8 NAT 15 Q9 15 Q10 15 Q11 HBs 16 Q12 HBV DNA 16 Q13 17-2 - Q14
More information医療レーザー脱毛の威力と限界
.... mm. CT WH W H W H W H... kcalkcal. 1. cal kcal 1 6 2 3. 4. 5. 1 6 6. B6 B12 B. BMI BMI30 C. D. kg mm . CT WH W H W H W H... kcalkcal . 1. cal kcal 1 6 2 3. 4. 5. 1 6 6. B6 B12 B. BMI BMI30 C. D.
More information卵巣癌の治療
K-net:2008.7.17 85 90 8 10 20 (FIGO) a (FIGO) b (FIGO) c (FIGO) a (FIGO) b (FIGO) c (FIGO) (FIGO) (FIGO) Risk factors Preventive factors Risk factors 35 PCO, Preventive factors? Relative risk
More informationWHO Library Cataloguing in Publication Data 2003, Wilkinson,Richard Marmot,Michael Social determinants of health SDH The social gradient Stress Early life Social exclusion Work Unemployment Social support
More information2
( ) 1 1 2 3000 2500 2000 1500 1000 500 0-500 -1000-1500 18 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 3 3 1980 ( ) 1980 43 87 33 10 10 2001 80 07 58.6
More information94.7 H22 H22 140,000 120,000 3.31 3.24 3.02 2.85 116,435 122,529 126,317 3.5 3 100,000 80,000 77,498 93,159 105,099 112,878 2.73 2.62 2.51 2.5 2 60,000 40,000 20,000 23,412 28,790 34,786 39,571
More informationuntitled
P125(2) ()()()() ()()() ()()()()()()() 1 - - - - - - - - - - - - - - -1 - - - 105 105 105120 105120 105120 105120 105120 90 90 90 90 90 105 105 105 105 105120 105120 105120 105120 90 90 90 90 85 85 85
More information2 4 5 6 7 8 9 HP 10 11 12 14 15 , 16 17 18 19 20 21 22 24 25 26 27 28 29 30 31 34 35 36 37 38 39, 40 41 42 43 44 45 46 47 48 49 50 51 52 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 1 70 71 72
More information平成16年度外務省事後評価実施計画策定について
2005 1 HP http://www.mofa.go.jp/mofaj/area/n_korea/index.html http://www.mofa.go.jp/mofaj/area/n_korea/abd/rachi_mondai.html HP http://www.mofa.go.jp/mofaj/area/n_korea/abd/6kaigo3_gh.html http://www.mofa.go.jp/mofaj/press/danwa/17/dga_0414b.html
More informationリコー工業所有権紹介|リコーテクニカルレポートNo.23
138 Ricoh Technical Report No.23, SEPTEMBER, 1997 Ricoh Technical Report No.23, SEPTEMBER, 1997 139 140 Ricoh Technical Report No.23, SEPTEMBER, 1997 Ricoh Technical Report No.23, SEPTEMBER, 1997 141 142
More information日本医師会雑誌第131巻第10号
B C 100 12 11 13 3 C 4 C Q&A B C 54 B B B B Q&A B B HBV 20 HBV B B B B HBV HBV HBV HBV 2 HBV HBV HBV A HBV HBV HBV HBV HBV Q37 HBV HBV HBV 1015 B B B Q51 B HBV B B HBV B HBV HBV HBV B B B HBV B HBV HBV
More informationuntitled
186 17 100160250 1 10.1 55 2 18.5 6.9 100 38 17 3.2 17 8.4 45 3.9 53 1.6 22 7.3 100 2.3 31 3.4 47 OR OR 3 1.20.76 63.4 2.16 4 38,937101,118 17 17 17 5 1,765 1,424 854 794 108 839 628 173 389 339 57 6 18613
More informationuntitled
1. 3 14 2. 1 12 9 7.1 3. 5 10 17 8 5500 4. 6 11 5. 1 12 101977 1 21 45.31982.9.4 79.71996 / 1997 89.21983 41.01902 6. 7 5 10 2004 30 16.8 37.5 3.3 2004 10.0 7.5 37.0 2004 8. 2 7 9. 6 11 46 37 25 55 10.
More information23 3 11 21 24 28 4 31,371 20,822 34,511 21,720 12,278 9,574 7,502 137,778 1 69 83.49% 70 15.55% 0.96 3.61% 40 1.19% 1055 29.65% 28 10 1 2 230,250 43,150 656 138,000 137,832 137,820 121,000 30,000 246,800
More information16 41 17 22 12 10
1914 11 1897 99 16 41 17 22 12 10 11 10 18 11 2618 12 22 28 15 1912 13 191516 2,930 1914 5,100 43 1.25 11 14 25 34364511 7.54 191420 434849 72 191536 1739 17 1918 1915 60 1913 70 10 10 10 99.5 1898 19034.17.6
More information製品案内 価格表 2014/4/1
4 (17) 3 43 5/20370/ 231(504,150) 11 12 10 14-16 10 3 100 17 100kg 5-6 3 13 3 18 18 # # # # #$$ %&$ ' ()* +,-% ' #). +,-%'% / ' # # #$ %&&&'( %)* +'(#$ #$ %&&&'( ++,-). +'(#$ #$ /'( + /0)- +'(#$ %&&&'(
More information3.ごみの減量方法.PDF
- 7 - - 8 - - 9 - - 10 - - 11 - - 12 - ( 100 ( 100 - 13-123,550,846 111,195,762 92,663,135 ( 12 25 37 49.2 16 33 49 65.6 15 30 44 59.0 2.5kg) ( 5kg) ( 7.5kg) ( k ( 123,550,846 111,195,762 92,663,135 (
More information.o...EPDF.p.indd
Social and Environmental report 28 1 2 3 5 7 9 11 12 17 18 19 22 24 25 26 27 28 29 3 2 3 4 5 6 7 4 1 2 5 3 6 8 9 1 1 2 3 4 11 12 1 2 3 4 13 14 1 2 3 4 5 6 7 8 15 16 17 1 2 3 18 19 1 2 3 4 2 21 1 2 3 4
More information養育費相支セ_NL04.indd
Family Problems Information Center 4 N E W S L E T T E R 2010.8 N E W S L E T T E R 2 0 1 0. 8 4 N E W S L E T T E R 2 0 1 0. 8 Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 4 4 Family Problems Information Center URL http://www1.odn.ne.jp/fpic/youikuhi/index.html
More informationidwr2008_21
VanC 521 0.63 0.24 2.12 2.27 1.07 0.98 1.75 0.70 27.24 0.76 1.16 0.35 1.26 0.71 2SD 1SD 1SD 2SD A SD 0.21 0.58 3.02 7.02 1.89 0.70 0.20 0.72 0.11 0.37 0.43 0.04 0.79 0.39 5515 6.19 Streptococcus pyogenes
More information10Disclosure_H0104_0618
01 SHIZUOKA BANK GROUP REPORT 2010 SHIZUOKA BANK GROUP REPORT 2010 02 03 SHIZUOKA BANK GROUP REPORT 2010 SHIZUOKA BANK GROUP REPORT 2010 04 05 SHIZUOKA BANK GROUP REPORT 2010 06 SHIZUOKA BANK GROUP REPORT
More informationサイトメトリー12-1.indd
Cell Growth Inhibition and Apoptosis in Cancer Cells Kazuki Omoteyama, Shoichi Inoue and Alaa-eldin Salah-eldin Department of Environmental Medicine and Informatics, Graduate School of Environmental Earth
More information1
1 2 3 4 5 0% 20% 40% 60% 80% 100% 6 7 8 0% 20% 40% 60% 80% 100% 9 0% 20% 40% 60% 80% 100% 10 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 2529 (n=17) 3034 35 (n=21) (n=17) 2529 (n=19) 3034 35 (n=34) (n=64)
More informationBAANs理論に基づく保健指導プログラム暫定版
WHO 4 5 10% L- -3 RNA L - 1960-3 RNA mrna Bio Activating Advanced Nutrients BAANs BAANs BAANs BAANs L- (NO) -3 EPA, DHA) RNA RNA DNA TNF- PAI-1 ( ) BAANs 40 50% 20% 1Kg 7,000Kcal 50Kcal 11 50Kcal
More information.,,,.,,,,,.,,,, Inoue,.,,,,.,.,,.,,,.,.,,,.,,,,,.,,.,,.,,,.,,,,
J. of Population Problems. pp.,,,,.,,,.,,,.,,,,.,,,.,,,.,.,, p..,.,.,,.,,, .,,,.,,,,,.,,,, Inoue,.,,,,.,.,,.,,,.,.,,,.,,,,,.,,.,,.,,,.,,,, .,.,,,.,.,,,,,.,,,,.,, Giddens, Chaney,,,,.,,,.,,,,.,.,,.,,.,.,,.,..,
More informationuntitled
2011 59 2 193 203 c 2011 1975 2005 1 2 1 2011 1 17 5 23 5 30 Joinpoint 1975 2005 31 2000 2005 1.7 1999 2005 2.8 Joinpoint 1. 1981 1 30 30 Joinpoint Kim et al., 2000 Joinpoint 1975 2005 2. 1975 2005 Matsuda
More informationVSR-100(01).g
REMOTE ON OFF VOL 3V IR Controlled Speaker-Level In-Wall Volume Control 3V 9 0 8! 9 7 6 1 2 3 4 5 6 9 9 0 1 2 3 4 5 6 7 8 9 0! X8 X4 X2 X1 X8 X4 X2 X1 REMOTE ON OFF VOL 1 2 3 REMOTE ON OFF VOL G0709-1
More information1 5 6 2 3 7 8 4 5 9 10 6 7 11 12 8 1 2 3 4 5 6 7 1989 25.0% 19901999 6 2000 15.0% 9 13 1 2 3 4 5 50 2 5180 45.0% 81 35.0%, 5.0% + +, 5.0% +, 1, 5 +, 3 14 10 0% 20% 40% 60% 80% 100% n=20 3 5 2 n=20 55.0%
More information2001 2003 2005 2006 2007 2008
2001 2003 2005 2006 2007 2008 60 etc. http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm http://nosmoke.hp.infoseek.co.jp/yuugaibussitu.htm 23.5% 2.8% 2.8% 3.4% 30.3% 9.9% 11.5% 15.8% AAN 65
More informationuntitled
HCV 150 HCV 13 3 13 4 13 8 14 2 14 2 14 8 15 3 15 8 17 3 7 8 18 3 ----- i Q1 1 Q2 1 Q3 1 Q4 2 Q5 3 Q6 3 Q7 3 Q8 4 Q9 4 Q10 : 5 6 Q1 6 Q2 7 Q3 7 8 Q4 8 Q5HCV 8 Q6HCV 9 Q7HCV 9 Q8NAT 10 Q9 10 Q10 11 Q11
More informationuntitled
Conditions of Social Innovation: Tow Case Studies of Reconstruction Project in Minami-Sanriku Yanyan Li 2015 4 NHK GRA 1 1000 2015 89 Komazawa Journal of Sociology No.48, 2016 2011 4 20112015 2 4 2011
More information5 ex. neo^r ex. P. ips induced Pluripotent Stem cells 4 ES ex. ex. DNA
4 MZ DZ MZ DZ ex.mz 0.8 DZ 0.4 2 ex. 0.8 ex. MZ 0.8 DZ 0.6 ex. MZ 0.8 DZ 0.1 E LDL E2 E3 E4 128 152 E2 CC E3 CR E4 RR 10 ex. G6PD CYP CYP P CYP CYP CYP3 CYP CYP 5 ex. neo^r ex. P. ips induced Pluripotent
More informationPowerPoint プレゼンテーション
核医学の画像所見からみた骨転移 神奈川核医学研究会東海大学医学部付属病院放射線技術科山下高史 本日の内容 1. 骨転移が分かる核医学検査の基礎 2. 核医学画像における骨転移の見方 3. 骨シンチ vs DWIBS 4. 骨シンチ使用されている主な解析ソフト 1. 骨転移が分かる核医学検査の基礎 骨シンチ ( 99m Tc-HMDP( クリアホ ーン )/MDP) 18 FDG-PET(PET/CT)
More informationJAGES 1 http://www.mlit.go.jp/common/000135841.pdf http://www.mhlw.go.jp/file/04-houdouhappyou-12004000-shakaiengokyoku-shakai-fukushikibanka/270624houdou.pdf_2.pdf 21 59 10 vs 9 8,500 8,000 7,500 7,000
More informationSBSGroup_CSR_h01-h04_0820CS5.ai
CSR Report 2015 SBS GROUP CSR REPORT 2015 1 CSR Report 2015 Contents 3 11 19 22 5 7 15 17 21 2 SBS GROUP CSR REPORT 2015 3 4 SBS GROUP CSR REPORT 2015 5 6 SBS GROUP CSR REPORT 2015 7 8 SBS GROUP CSR REPORT
More informationP r o g M e d suppl ProgressinMedicineVolsuppl. 第9回アミオダロン研究会講演集 12月3日 12月4日 12月6日 12月25日 12月8日 2004年1月5日 図5 胸部X線とCTの経過 図6 退院7カ月後の胸部X線写真とCT 200 4年8月 期に行う必要があった 最終的には マイコプラズマ抗体が51 2倍と著増し ており ペニシリン系抗生物質およびミノサイクリン
More informationJ. Jpn. Acad. Nurs. Sci., Vol.25, No.1, pp.13-22, 2005 Decision Making under the Uncertainty; Process of Decision from Diagnosis to Preventive- Operat
J. Jpn. Acad. Nurs. Sci., Vol.25, No.1, pp.13-22, 2005 Decision Making under the Uncertainty; Process of Decision from Diagnosis to Preventive- Operation in Patient with Asymptomatic Cerebrovascular Diseases
More information2007 Environmental Report 1. 2. 3. 4. 5. 2 CONTENTS 4 6 8 10 Topic 01 2007 11 12 Topic 02 Topic 03 14 16 17 18 Topic 04 Topic 05 Topic 06 Topic 07 19 19 20 20 Topic 08 Topic 09 21 22 23 24 24 24 25 26
More informationReviews Original Case reports 0.2 0.5 1.0 2.0 0.77 0.64 0.67 0.56 0.81 1.02 1.01 1.14 USA HIP Sweden Malmö Östergötland Kopparberg Stockholm Gothenburg UK Edinburgh Canada NBSS-1 RR=0.82 (0.72-0.95)
More informationscience
science IT PERSON TO PERSON EU IT IT WHO TV I T Harvard University Brigham and Women s Hospital, Renal Division UCSF CT MRI IT 1 40 17 3 27 Winslow 1949 Impact Factor 50 1 16 1 NIH Samuel W. Cushman
More information