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9 1) Ogawa, H., Lazarus, G. S., Hopsu-Havu, K.: The Biological Role of Proteinases and their Inhibitors in Skin, Univ. Tokyo Press (1985) 2) Sottrup-Jensen, L., Stepanik, T. M., Kristen sen,t., Wierzbicki, D. M., Jones, C. M., Lon blad,p. B., Magnusson, S., Petersen, T. E.: J. Biol. Chem., 259, (1984) 3) Kan, C. -C., Sjolomon, E., Belt, K. T., Chain, A. C., Hiorns, L. R., Fey, G.: Proc. Natl. Acad. Sci. USA, 82, (1985) 4) Sottrup-Jensen, L., Sand, O., Kristensen, L., Fey, G. H.: J. Biol. Chem., 264, (1989) 5) Eccleston, E. D., Howard, J. B.: J. Biol. Chem., 260, (1985) 6) Delain, E., Barray, M., Tapon-Bretaudiere, J., Pochon, F., Marynen, P., Cassiman, J. -J., Ber ghe,h. V., Leuven, F. V.: J. Biol. Chem., 263, (1988) 7) Moestrup, S. K., Gliemann, J.: J. Biol. Chem., 264, (1989) 8) Strickland, D. K., Ashcom, J. D., Williams, S., Burgess, W. H., Migliorini, M., Argraves, W.

10 26) Ž Ä E c r Æ : _ W, 48, (1991)27) Sottrup- Jensen, L.: J. Biol. Chem., 264, (1989)28) Feinman, R. D., (ed.): Chem Marynen, P., Devriendt, K., Van den Berghe, H., Cassiman, J. J.: FEBS Lett., 262, (1990) 24) Philip, A., O'Connor-McCourt, M. D.: J. Biol. Chem., 266, (1991) Mori, T., Miyamoto, Y., Iijima, N., Kitabata ke,k., Kohsaka, S.: Brain Res., 567, (1991) 19) Armstrong, P. B., Mangel, W. F., Wall, J. S., Hainfield, J. F., Van Holde, K. E., Ikai, A., Quigley, J. P.: J. Biol. Chem., 266,

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