SMXA-5

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1 2 Key words 2 Type 2 diabetes Insulin resistance Impairement of insulin secretion Spontaneously diabetic model animal high-fat diet diabetogenic gene

2 SMXA-5

3 3 SM.A-T2dm2sa SMXA-5 SM/J A/J 2 HND Horio-Niki diabetic 4 HND 5 HND C57BL/6J(B6) 6 (A) 12 (B)

4 6 HND C57BL/6J(B6) 7

5 Diabetogenic factors of type 2 diabetes Studies in spontaneously diabetic animal models Type 2 diabetes, Insulin resistance, Impairement of insulin secretion, Spontaneously diabetic model animal, High-fat diet, Diabetogenic gene Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University Key words

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