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1 32, 21-25, 2012 CASLE cm 1 2 CEA 3 4 CEA cm

2 ; cm 4. ; 2. ; 3. ; 5. 2 ; 120 ng/ml Mφ 6 7, 8 9

3 23 6. ; 9. ; 7. ; 10. ; CK3 CK3

4 24 1, % 4,5 0.2% PAS MUC1 MUC2 MUC5AC MUC6 CD Ultimobranchial body Thymic remnants Solid cell nests Parafollicular cells Teratoma Thyroglossal duct remnants Metaplasia of normal, inflamed, or neoplastic follicular cells

5 Muc1 2 1 Diaz - Perez R et al : Primary mucinous adenocarcinoma of the thyroid. Cancer 38 : , Mizukami Y et al : Mucin - producing poorly differentiated adenocarcinoma of the thyroid. A case report. Pathol Res Pract 186 : , : Shimaoka K et al : Metastatic neoplasms in the thyroid gland. Cancer 15 : , : 30 : , : Grawitz 2 39 : , : 45 : , : 1 35 : , : 1 42 : , Baloch ZW et al : Tumor - to - tumor metastasis to follicular variant of papillary carcinoma of thyroid. Arch Pathol Lab Med 123 : , Kasantikul V et al : Adenosquamous carcinoma of the thyroid : a case report and review of the literature. J Med Assoc Thai 78 : , : 1 54 : , Misonou J et al : Adenosquamous carcinoma originating from the thyroid gland report of a case and review of the literature. Gan No Rinsho 32 : , Minagawa A et al : A case of primary mucoepidermoid carcinoma of the thyroid : molecular evidence of its origin. Clin Endocrinol 57 : , Bakri K et al : Adenosquamous carcinoma of the thyroid after radiotherapy for Hodgkin s disease. A case report and review. Cancer 52 : , Mizukami Y et al : Primary mucin - producing adenosqua mous carcinoma of the thyroid gland. Acta Pathol Jpn 37 : , Nicolaides AR et al : Adenosquamous carcinoma of the thyroid gland. J Laryngol Otol 103 : , LiVolsi VA et al : Squamous cells in the human thyroid gland. Am J Surg Pathol 2 : , 1978

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24 24 1) Hales M, Resenau W, Okerlund MD, et al: Carcinoma of the thyroid with a mixed medul lary and follicular pattern: morphologic, im munohistochemical, and clinical laboratory studies. Cancer 50: 1352-1359,

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表 1. 乳 頭 癌 の 特 殊 型 ( 取 扱 い 規 約 第 7 版 ) 乳 頭 癌 Papillary carcinoma 特 殊 型 Variants 1) 濾 胞 型 乳 頭 癌 Papillary carcinoma, follicular variant 2) 大 濾 胞 型 乳 頭 山 梨 大 学 医 学 部 人 体 病 理 学 講 座 Variants of papillary thyroid carcinoma Department of Pathology, Faculty of Medicine, University of Yamanashi Naoki Oishi and Tetsuo Kondo 甲 状 腺 乳 頭 癌 は, 腫 瘍 細 胞 の 特 徴 的 な 核

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