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1 ｨ ｨｴ02ｨｦ ｨｪｨ ｨｮ ﾂｨｪ06ｨｦ ｨ ｨｺ02ｨｨ02ｨｦ ｨ ｨｺｨ 0102ｨｬｨｨｨｺｨ ｨ 0606ｨｬ II ｨｺ09ｨ 01ｨ 02ｨｨ06ｨｪｨ 05ｨｹｨｪｨ 07 08ｨｺｨ 0102ｨｬｨｨ07 00ｨｨｨｺ ｨｨｨｨ 2003

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3 ﾁ0308

4 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ 0903 ﾁ ｪ ｨｹｨ ｨ ｨｪ0609ｨ ｨ ｨｮ ﾂｨｪ04ｨｦ ｨｬｨ ｨｰ ｨｨ ﾂ0209ｨｺｨｨｨｦ 0202ｨｪｨｰ ｨｰｨｨｨｪ06ｨｨ ｨｺ09ｨ 01ｨｨ ｨｨ ｨｰ0607 ｪ ｨｪｨ ｨｨｨ ﾂｨ 09ｨｰ ｨｰ0802 ﾂｨ 06ｨｴ ｨｪｨ 08ｨｮ0302ｨｪｨｨ ｨｰ0606ｨｰ ｨｪｨｨ07. 02ｨｪ 08ｨ 0409ｨｨ09ｨ 02ｨｰ ｨｮ05ｨｹｨｰｨ ｨｰ02 04ｨ ｨｰ08ｨｮ01ｨｪ02ｨｪｨｨ07 ｨｬ0209ｨｰｨｪ06ｨｦ ｨｰ ｨｰ01ｨ ﾂｨｨ (ｨｪ02ｨｮ0106ｨ ｨｪｨ 07 06ｨ ｨｮ09ｨｹ, ｨｪ02ｨｮ0106ｨ ｨｪｨ 07 ｨｨ ｨｴｨ 07 ｨｰ ｨ, ｨｪｨｨ02 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 ｨｨ 0905ｨ 03ｨｪ0609ｨｰｨｨ 06ｨｺ08ｨｮ03ｨ 06ｨｴ02ｨｦ ｨｨ 0108.), ｨｪｨ 05ｨｨ ﾂｨｨ07 ｨｪ02ｨｺ06ｨｰ ｨ ｨ ｨ ｨｪｨｨｨｦ ( ｨｰ ｨｮ01ｨｨ09ｨｰ06ｨｦ 01ｨｨ09ｨｰ06ｨｪｨｨｨｨ, ｨｪ , ｨ 05ｨｺ ｨｨ04ｨｬｨ ) ｨｪ0609ｨｰｨｨ ｨ 0302ｨｪｨｪ04ｨｦ 00ｨｨ ｨｨ ｨｰ ｨｰ0802 ﾂｨ 02ｨｰ0907 ｨｺｨ ｨｺ ｨ 09ｨｰｨｪ ｨｪｨｨ ｨｰ05ｨｨ090609ｨｰｨｹ 09ｨｰ ｨ 09ｨｰ09ｨｮ02ｨｰ ｨｪｨｨｨｺｨｪ060902ｨｪｨｨ ｨ ｨｮ01ｨｨｨｰ020502ｨｦ 0008ｨｨｨ ｨｺ ｨ ｨ ｨ ｨｪｨｨｨｦ 09 ｨｺ0603ｨｮ, 09ｨｪｨｨ0302ｨｪｨｨ ｪ 09ｨ 03ｨｪ04ｨｦ 00ｨ ｨｺｨｰ ｨｨ05ｨ ｨｺｨｰｨｨｨｺ02 ｨｬｨｨｨｺ ｨ ｨｨｨ ｨｺｨｰｨｨ09ｨｪ04ｨｬｨｨ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ04ｨｬｨｨ ｨｰ09ｨ ｨｬｨｨ ｨｬ0209ｨｰｨｪ ﾂ02ｨｪｨｨ07 00ｨｨ ｨｨ ｨ ｨｰ ｨ 08ｨ ｨｰ04, ｨ ｨｴｨｨ ｨｬｨ 05ｨｹ010200ｨｨ ｨｬｨ ｨｹ ｪ ｨｪ060904ｨｦ ｨ 08ｨ ｨｰ 0105ｨｨｨｰ0205ｨｹｨｪ ｨｦ09ｨｰ09ｨｨ07, ｨｰｨ ｨｴｨｨｨｦ 0906ｨ 06ｨｦ ｨｹ, ｨ ｨｴｨｨｨｦ 3,7% ｨｬｨ 05ｨｹ010200ｨｨ01ｨ. 08ｨ 08ｨｬｨ ｨｺ ｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｺｨｰ ｨ 08ｨ ｨｰｨ ｨ ｨｪ ｨ ｨｪ0609ｨｰｨｹ ｨ ｨｰｨｹ 00ｨｮｨｪｨｺ02ｨｨ ｨｰ ｨｪ0204ｨ 09ｨｨ09ｨｨｨｬ06 06ｨｰ ｨｰｨｨ07ｨ ｨｨ ｨｺ080202ｨｨｨｨ, ｨ ｨｰｨ ｨｺ ｨｨｨｪ00ｨｨ02ｨｨ08ｨｮ06ｨｴｨｨｨｬｨｨ ｨｦ09ｨｰ09ｨ ｨｬｨｨ ｨ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ ｨｰ: ｨｬ04ｨｰｨｹ07 ｨｪ0600 ｨｰ ｨｦ ｨｦ 09 ｨｬ040506ｨｬ ｨｨ 0904ｨｰｨｨ08ｨ ｨｪｨｨ ｨｰ02ｨｪ0202ｨｬ ｨｪｨ ｨｮ ｨｨ ｨｬ020307ｨ 05ｨｹ ｨｪ0609ｨｰｨｨ ｨｪｨ ｨｪ060907ｨｰ ｨｰ06ｨｪｨｺｨｨｨｬ ｨｬ ｨｬｨ ｨｹ ｨ 08ｨ ｨｰ ｨ 0409ｨｰ ｨ 02ｨｰ, 06ｨ 08ｨ 04ｨｮ07 ｨｰ06ｨｪｨｺｨｮ06 ｨ ｨｰｨｪｨｮ ｨｪｨｺｨｮ. ﾁ ｨｬｨｨｨｪｨｮｨｰ ｨｪｨｺｨｮ 09ｨｬ0409ｨ 06ｨｰ ｨｰ ｨｦ ｨｦ ｨ ｨｪｨｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ ｨ 08ｨ ｨｰｨ, ｨｪｨｪ0402 ｨｮ ｨｨ02, 09ｨｰ08ｨ 01ｨ 06ｨｴｨｨ ｨ 0302ｨｪｨｪ04ｨｬ 00ｨｨ ｨｨ ｨｬ 09ｨｰ0607, 0706ｨｺｨ 04ｨ 05ｨｨ, ﾂｨｰ ｨｪ06ｨｦ ｨｮ ｨｰｨ ｨｰ06 ﾂｨｪ06, ﾂｨｰ06ｨ 04 09ｨｪｨｨ04ｨｨｨｰｨｹ 0706ｨｰ05ｨｨ090609ｨｰｨｹ ｨｺ0603ｨｨ ｨｨ ｨｮ09ｨｰ08ｨ ｨｪｨｨｨｰｨｹ 04ｨ 07ｨ ｨｰｨ ｨｪｨ ｨｪ02ｨｦ ｨｪｨｨ0302ｨｪｨｨ ｨｺｨｰｨ ｨｪｨ ｨｪ020902ｨｪｨｨ ｨ 08ｨ ｨｰｨ ｨｰ ｨｹ ﾂ02ｨｪｨｨ02 ｨｪ ｨ ｨｹ ｨｺｨ ｨｺｨｨｨｬｨｨ-05ｨｨｨ 06 ｨｪ ｨ ｨｰ0205ｨｹｨｪ04ｨｬｨｨ ｨｺｨｰｨ ｨｬｨｨ, ｨｪ02 06ｨｺｨ ｨ ｨｰ08ｨｨ02ｨ ｨｰ0205ｨｹｨｪ ｨｦ09ｨｰ09ｨｨ07 ｨｪｨ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨｨ02, ｨ ｨｨ0601ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ ｨｺｨ 04ｨ ｨｰ0205ｨｨ ｨｺ080609ｨｨ ｨｨ ｨ ｨｪｨ 05ｨｨ0404 ｨｬ06 ﾂｨｨ. 0308ｨｨ 0105ｨｨｨｰ0205ｨｹｨｪ06ｨｬ ｨｨ ｨｹ040609ｨ ｨｪｨｨｨｨ ｨ 08ｨ ｨｰｨ 09 06ｨｰ010205ｨｹｨｪ ｨｮ ﾂｨ ｨ 0409ｨｨ09ｨ 05ｨ 09ｨｹ 09ｨｮ010609ｨｰｨｹ ｨｺ0603ｨｨ ｨｰｨｨ ｨｺｨ 04ｨ ｨｪｨｨ02ｨｬ 0905ｨｮ03ｨｨｨｰ ｨｪｨｪｨ 07 ｨｨｨｪ01ｨｨ09ｨｨ01ｨｮｨ 05ｨｹｨｪｨ 07 ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ ｨｺ ｨｬｨ 05ｨｹ010200ｨｨ ｨ ｨｴｨｨｨｬ ｨｨｨｪ02ｨｪｨｨ07ｨｬ ｨ 08ｨ ｨｰ ｨｮ0106ｨ 02ｨｪ ｨｨｨｬ02ｨｪ02ｨｪｨｨｨｨ, ｨｪ02 06ｨ 05ｨ 01ｨ 02ｨｰ 09ｨｨ05ｨｹｨｪ04ｨｬ 04ｨ 07ｨ 0106ｨｬ, ｨｪ ｨｰｨ ｨｰ 0707ｨｰ02ｨｪ ｨｪｨ ｨｰ0205ｨｹｨｪ06ｨｬ ｨ 0205ｨｹ02 ｨｨ COMMON SUPERFICIAL FUNGAL INFECTIONS IN PATIENTS WITH AIDS Aly R. Department of Dermatology University of California ｪ San Francisco Medical Center 05ｨ ｨｪ-0808ｨ ｨｪ02ｨｨ09ｨｺ06, Superficial fungal infections such as seborrheic dermatitis,tinea pedis,tinea corporis, and onychomycosis are common in patients infected with human

5 130606ｨｬ II. 0105ｨ 09ｨ 1 5 immunodeficiency virus (HIV). In communities where HIV infections are frequent, some of these clinical presentations serve as markers of the stage of HIV infection. The diagnosis of superficial fungal infection in HIV-positive patients may be difficult because of atypical clinical manifestations. Therefore, to ensure a correct diagnosis, skin scrapings should be collected for potassium hydroxide preparations and cultures. Most forms of dermatophytosis in HIV-positive patients respond well to many topical antifungal agents, such as azoles, terbinafine, and ciclopirox olamine. If the disease is chronic and extensive, then systemic antifungal agents are effective ﾁ ｨｺｨ 01ｨｹ0209ｨ , 00ｨｨｨｪ060008ｨ ｨ ｨ ｨｪｨｺｨｰ-0302ｨｰ0208ｨ ｨｮ080009ｨｺｨｨｨｦ ｨｮ01ｨ 0809ｨｰ0902ｨｪｨｪ04ｨｦ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺｨｨｨｦ ｨｮｨｪｨｨ ｨｨｨｰ02ｨｰ ｨｨｨｬ02ｨｪｨｨ ｨ ｨｺｨ ｨ ｨ 05ｨ ｨｪｨｺｨｰ-0302ｨｰ0208ｨ ｨｮ ｨ ｨｪ0606 ﾂ02ｨｰ090208ｨｰｨｹ ｨｺｨ ｨｪｨ ｨ ｨ ｨｹ 0108ｨ ｨｬｨ ｨｰｨｨ ﾂ0209ｨｺ0602 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 ｨｨｨｬｨｬｨｮｨｪ06ｨｺ06ｨｬ0806ｨｬ02ｨｰｨｨ080609ｨ ｨｪｨｪ0401 ｨ 0605ｨｹｨｪ ｨｰ08ｨ ｨｪｨ ｨ ｨｪ ｨｰ06 ｨ ｨ ｨｪ ｨｰ09ｨｨ07ｨｬｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ ﾂ02ｨｪｨｨ ｨｨ ｨｰ08ｨ ｨｪ090705ｨ ｨｪｨｰｨ 02ｨｨｨｨ ｨｨ ｨｨ ｨｹ040609ｨ ｨｪｨｨｨｨ ｨｺ0608ｨｰｨｨｨｺ0609ｨｰ020806ｨｨ ｨｨ 0108ｨｮ00ｨｨ ｨｺｨ 0809ｨｰ ｨｪｨ 09ｨｰ0607ｨｴ ｨｬ07 ｨｰ ｨｨｨｬｨｬｨｮｨｪｨｪ ｨｺｨｰ ｨ 06ｨｰ 09 ｨｨｨｪ0002ｨｺ02ｨｨ02ｨｦ, ｨ ｨｪｨｪ06ｨｦ 00ｨｨ08ｨｮ0906ｨｬ 06ｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨ ﾁ ｨｺｨ (0006 ﾁ), ｨｺ06ｨｰ0608ｨ ｨｦ ﾂｨ ｨｰ ｨ 09ｨｪ06ｨｦ 0708ｨｨ- ﾂｨｨｨｪ06ｨｦ ｨｨｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨ ｨｰｨｪ06, ﾂｨｰ06 ｨｨｨｬ0202ｨｰ ｨｬｨ ｨ ｨｨｨｬ ｨｹ ｨｬ020301ｨｮ ｨｰ0607ｨｪｨｨ02ｨｬ ｨｨｨｬｨｬｨｮｨｪｨｪ06ｨｦ 09ｨｨ09ｨｰ02ｨｬ04 ｨｨ ｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ02ｨｦ ｨｪ0207ｨ ｨｰ060002ｨｪｨｪ06ｨｦ ｨｨ05ｨｨ ｨｰｨｮｨｪｨｨ09ｨｰｨｨ ﾂ0209ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｰｨｨ 08ｨｰｨ ｨｰｨｮｨｪｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｨ02 ｨｬｨｨｨｺ ｨ ｨｪｨｨ04ｨｬ04 ｨ ｨｺｨｰｨｨ09ｨｨ08ｨｮ06ｨｰ ｨｮ ｨｨ0701, ｨｮ0106ｨ ｨｪ ｨｪｨｨ01 ｪ 05ｨｰ06 ｨｨｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨｪ ｨｰ0607ｨｪｨｨ ｨｨ 0006 ﾁ-ｨｨｨｪ0002ｨｺ02ｨｨｨｨ ｨｮ0302 ｨｪｨ 08ｨ ｨｪｨｪｨｨ01 09ｨｰｨ 01ｨｨ ｨ ｨ ｨ ｨｪｨｨ07, 02ｨｴ ｨ 0409ｨｨｨｰｨｨ07 ｨｨｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨ ｨｰ ｨｨ04ｨｪｨ ｨｺｨｨ ｨｨｨｬｨｬｨｮｨｪ0609ｨｮ ｨｨｨｨ ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴｨｨｨｦ ｨｺｨ ｨｪ01ｨｨ ｨｨ , ｨｺ06ｨｰ ｨｪｨ ｨ ｨ 06ｨｰ ｨ 0302 ｨｮ ｨ 0605ｨｹｨｪ0401, ｨｪｨ ｨｴｨｨ ｨｪｨ ｨｺ06ｨｨｨｪｨｰ02ｨｪ09ｨｨ09ｨｪ06ｨｦ ｨｰｨｨ ｨｰ080609ｨｨ08ｨｮ09ｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ (HAART) ｨｰ ｨｪｨｨ07 ｨｪｨ 0905ｨｨ04ｨｨ09ｨｰ ｨ ﾂｨｺｨ 01 08ｨｰｨ (ｨｪｨ ｨｴ02ｨｺｨ 01, ｨｰ ｨｬ ｨｨ ｨｬ0700ｨｺ06ｨｬ ｨｪ02ｨ 02, ｨｪｨ 01, ｨｺ02 ｨｨ ｨｺ08ｨ 09ｨｪ06ｨｦ ｨｺｨ ｨｦｨｬ02 00ｨｮｨ ) ｨｪｨ 08ｨ 09ｨｰｨ 06ｨｰ 0706 ｨｬ ｨ 0409ｨｨｨｰｨｨ07 ｨｨｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨ ｨｨ ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪ ｨ 0302ｨｪ ｨｰｨｹ ｨｨ09ｨｪ ｨｪｨｪ0401 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨｨｦ 09 09ｨｰｨ 01ｨｨｨｨ ｨ. 00ｨ ｨｰ0208ｨｨｨ 0504 ｨｨ ｨｬ02ｨｰ ｨ ｨｴｨｨ ｨｪｨ ｨ ｨｬｨ ｨｮ05ｨ ｨｰ0608ｨｪ06ｨｬ 0502 ﾂ02ｨｪｨｨｨｨ 09 05ｨ ｨｪｨｺｨｰ- 0302ｨｰ0208ｨ ｨｮ080009ｨｺ06ｨｬ 0002ｨｪｨｰ ｨ 0608ｨｹｨ 02 ｨｨ ｨｨ05ｨ ｨｺｨｰｨｨｨｺ ｨｨ ｨｨｨｪ0002ｨｺ02ｨｨ06ｨｪｨｪ04ｨｬｨｨ 04ｨ ｨ ｨ ｨｪｨｨ07ｨｬｨｨ ｨｨ ｨｨｨｪ0002ｨｺ02ｨｨ06ｨｪｨｪ06ｨｦ ｨ 0605ｨｹｨｪｨｨ ｨｨｨｬ ｨｰｨｺｨｨｨｪｨ ｨｪｨ ｨｬｨｨ ｨ ｨｪ06 ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺ ｨ ｨ ｨｪｨｨ02 32 ｨ 0605ｨｹｨｪ ﾁ ｨｨｨｪ0002ｨｺ02ｨｨ02ｨｦ ｨｬ06ｨｰ0806ｨｬ ｨｰｨｨ 08ｨｰｨ (0905ｨｨ04ｨｨ09ｨｰ06ｨｦ ｨｴ02ｨｺ, ｨｰ ｨｨ

6 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ ｨｬ0700ｨｺ ｨｪ02ｨ ｨ, ｨｰ0607ｨｪｨｨ02 07ｨ ｨｪｨｰｨ ｨｨ ｨｺｨ ); ｨ ｨｪｨ 05ｨｨ04ｨｨ080609ｨ ｨｪ04 01ｨ ｨｪｨｪ0402 ｨｨ09ｨｰ0608ｨｨｨｨ ｨ ｨｪｨｨ (05ｨ ｨ 0608ｨ ｨｰ0608ｨｪ ｨｺｨ 04ｨ ｨｰ0205ｨｨ, ｨｪｨ 05ｨｨ ﾂｨｨ ｨｮ00ｨｨ ｨｮｨｰ09ｨｰ09ｨｮ06ｨｴｨｨ01 07ｨ ｨｰ ｨｨｨｦ), ｨ ｨｪｨ ｨｬｨｪ0204 ｨｨ 03ｨ 0506ｨ 04 ｨｪｨ ｨｬ06ｨｬ02ｨｪｨｰ 0609ｨｬ06ｨｰ08ｨ, ｨｪ ｨｨ0904 ﾂｨｺｨｨ, 01ｨ 08ｨ ｨｺｨｰ0208 ｨｮ010601ｨ 04ｨ ｨｰｨｹ06 08ｨｰｨ ｨｬ06ｨｰ0802ｨｪｨｪ0401 ｨｪｨ ｨｬｨｨ ｨ 0605ｨｹｨｪ0401 ｨ 0405ｨｨ ｨｰ04 ｨｬｨ 04ｨｺｨｨ ( ｨｰｨ ｨｪ01ｨ 08ｨｰｨｪ06ｨｦ ｨｬ02ｨｰ0601ｨｨｨｺ02) ｨｨ ｨｪ02ｨｪ06 ｨｬｨｨｨｺ080609ｨｺ0607ｨｨ ﾂ0209ｨｺ0602 (06ｨｺ08ｨ 09ｨｺｨ ｨ ｨｬｨｮ) ｨｨ ｨ ｨ ｨｺｨｰ0208ｨｨ ｨｨ ﾂ0209ｨｺ0602 ( ｨ 05ｨ ｨ ｨｮ0806) ｨｨ ｨ ｨｪｨｨ ｨｮ05ｨｹｨｰｨ ｨｰ04 ｨｨ ｨｨ01 06ｨ 09ｨｮ030102ｨｪｨｨ ｨ 0605ｨｹｨｪ0401: 15 ｨ 0405ｨｨ ｨｨｨｪｨｲ02ｨｺ02ｨｨ06ｨｪｨｪ04ｨｬｨｨ ｨｪｨ 08ｨｺ06ｨｬｨ ｨｪｨ ｨｬｨｨ (09 ｨｪｨ 09ｨｰ0607ｨｴ ｨｬ07 ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ02 06ｨｰ08ｨｨ02ｨ 06ｨｰ), 0609ｨｰｨ 05ｨｹｨｪ ｨ 08ｨ 04ｨｨ05ｨｨ09ｨｹ 0708ｨｨ ｨｺ06ｨｪｨｰｨ ｨｺｨｰｨ ｨｨ 06ｨ ｨ ｨｪｨｪ0401 ｨ ｨｬｨｮ03 ﾂｨｨｨｪｨ ｨｨ 0601ｨｪｨ 0302ｨｪｨｴｨｨｨｪｨ ｨ 09ｨｰ 14 ｨ 0605ｨｹｨｪ0401 ｨ ｨｰ ｨｰ,15 ｨ 0605ｨｹｨｪ ｨｰ ｨｨ ｨｰ ｨ 0605ｨｹｨｪ ｨｰｨ ｨｰ ｨｬ020301ｨｮｨｪｨ ｨｪ06ｨｦ ｨｺ05ｨ 0909ｨｨ00ｨｨｨｺｨ 02ｨｨｨｨ (CDC, 1993) ｨｮ 5 07ｨ 02ｨｨ02ｨｪｨｰ0609 ｨ 0405ｨ 09ｨｰｨ 01ｨｨ07 081, ｨｮ , ｨｮ 1 ｪ 001, ｨｮ 14 ｨｪｨ ｨ ｨ 05ｨ 09ｨｹ 09ｨｰｨ 01ｨｨ07 003, ｨｮ 1 ｪ 09ｨｰｨ 01ｨｨ07 003, ｨｮ 2 ｪ 09ｨｰｨ 01ｨｨ ｨｨ ｨｮ ｨｰｨ 01ｨｨ ｨ ｨｮ ｨ ｨｰｨｨｨｰｨ ｨｬｨｨ 00 ｨｨ 05 ｨｮ ｨ 0605ｨｹｨｪ0401 ｨ 0405ｨｨ ｨｰｨ ｨｺｨｨ02 04ｨ ｨ ｨ ｨｪｨｨ07 ｨｺｨ ｨｺ ｨｰｨｮｨ 0208ｨｺｨｮ050204, 07ｨｨ020506ｨｪ020008ｨｨｨｰ, 0902ｨ ｨｦｨｪ04ｨｦ ｨｬｨ ｨｰｨｨｨｰ. 0308ｨｨ 0609ｨｬ06ｨｰ ｨｰｨｨ 08ｨｰｨ ｨ 0405ｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ ｨｮ06ｨｴｨｨ02 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07: ｨ ｨｪ00ｨｮ050708ｨｪ04ｨｦ 0102ｨｦ05ｨｨｨｰ, 00ｨｨ ｨｬｨｨ ｨｨ04ｨｨ09ｨｰ06ｨｦ ｨｦ 0806ｨｰ060906ｨｦ ｨｰｨｨ, ｨｬ02ｨｬｨ 08ｨ ｨｪ0604ｨｪｨ ｨｬｨ ｨｺｨ ｨｪ01ｨｨ010604ｨ (ｨｪｨ 0502ｨｰ04 ｨ 0405ｨｨ 08ｨ 0405ｨｨ ﾂｨｪ06ｨｦ 09ｨｰ020702ｨｪｨｨ ｨ 0302ｨｪｨｪ0609ｨｰｨｨ 06ｨｰ ｨ ｨｪｨｨ ﾂ02ｨｪｨｪ ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ0401), ｨｨｨｪｨｪ04ｨｦ 0806ｨｬｨ 0609ｨｨ01ｨｪ04ｨｦ ｨｨｨｰ, ｨｰ06 ﾂ02 ﾂｨｪ0402 ｨｺ ｨｨ0405ｨｨ07ｨｪｨｨ07, ｨｮ ｨ ｨｰｨ ｨｦｨｺ060705ｨ ｨｺｨｨ ｨｮ05ｨｹｨｰｨ ｨｰ04 ｨｨ ｨ ｨｪｨｨ07: ｨｮ 22 07ｨ 02ｨｨ02ｨｪｨｰ0609 ｨ ｨｪｨ ｨｦ0102ｨｪ06: 05andida spp. 0708ｨｨ ｨ ｨ ｨｺｨｰ0208ｨｨ0609ｨｺ0607ｨｨ ﾂ0209ｨｺ06ｨｬ ｨｨ ｨ ｨ ｨｺｨｰ0208ｨｨ ｨｨ ﾂ0209ｨｺ06ｨｬ ｨｨ ｨ ｨｪｨｨ ｨｰｨ 05ｨｹｨｪ ｪ 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ ｨｬ 09 ｨｬｨ 04ｨｺ02 ｨｨ ｨｰｨ ｨｪｨ ｨ ｨ ｨｮ ｨ ｨｮ ｨｬ06ｨｰ0806ｨｬ 07ｨ 02ｨｨ02ｨｪｨｰ04 04ｨ ｨｪ0705ｨｨ ｨ ｨｪ06ｨｪｨｨｨｬｨｪｨｮ06 ｨ ｨｪｨｺ02ｨｰｨｮ ｨｪｨ 0609ｨｪ0609ｨ ｨｪｨｨｨｨ ｨｺ06ｨｰ060806ｨｦ ｨｬ ｨｪｨｨ05ｨｨ ｨｺｨ ｨｺ ﾂｨ 09ｨｰ06 05ｨｰｨ 0008ｨｮ0707ｨ 07ｨ 02ｨｨ02ｨｪｨｰ0609 ｨｮ01ｨ 03ｨｨ09ｨ 02ｨｰ 04ｨ ｨｰｨｹ06 08ｨｰｨ, ｨｪｨ 05ｨｨ ﾂｨｨ ｨｪ06ｨｦ 0708ｨｨ0904 ﾂｨｺｨｨ (ｨｰｨ ｨ ｨ ｨｺ06ｨｺｨｮ0802ｨｪｨｨ02), 07ｨ ｨｰ ｨｨｨｦ ｨｰ060806ｨｪ04 08ｨ 0405ｨｨ ﾂｨｪ ｨ ｨｪ0609 ｨｨ 09ｨｨ09ｨｰ02ｨｬ, ｨｮｨｴｨｨ02 03ｨ 0506ｨ 04 ｨｨ 03ｨ 0506ｨ 04 ｨｪｨ ｨｬ06ｨｬ02ｨｪｨｰ 0609ｨｬ06ｨｰ08ｨ. 00 ｨｪｨ 0302ｨｬ ｨｨ ｨ ｨｪｨｨｨｨ ｨ ｨｮ ｨ 02ｨｨ02ｨｪｨｰ ｨｰ0607ｨｪｨｨ02 00ｨｨ00ｨｨ02ｨｪ ｨｰｨｨ 08ｨｰｨ ｨ ｨｪ02ｨｮ ｨｰ090608ｨｨｨｰ0205ｨｹｨｪ04ｨｬ ｪ 07ｨ 02ｨｨ02ｨｪｨｰ04 ｨｪ ｨｮ050708ｨｪ06 ﾂｨｨ09ｨｰｨｨ05ｨｨ 04ｨｮｨ 04 ｨｨ ｨｪ02 ｨｨ ｨｹ040609ｨ 05ｨｨ ｨｪｨｨｨｰ0205ｨｹｨｪ ｨｰ09ｨ ｨ ｨｪｨ 02ｨｨｨｨ ｨｰｨｨ 08ｨｰｨ ｨｰ09ｨｨ02 05ｨｰ ｨｬ060005ｨｨ ｨｨｨｰｨｹ0907 ｨｨ ｨｨ01ｨｨ09ｨｨ080609ｨ ｨｰｨｹ 07ｨ ｨｰ ｨｨ ﾂ0209ｨｺｨｨ02 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 ｨｪｨ 0905ｨｨ04ｨｨ09ｨｰ06ｨｦ 06ｨ ﾂｨｺ ｨｰｨｨ 08ｨｰｨ ｨｦ ｨｨ ｨｪ ｨｮ050708ｨｪ04ｨｦ ｨｮ ｨ ｨｰｨｹ06 08ｨｰｨ ｨ 09ｨｰ09ｨｮ02ｨｰ ｨｺ060506ｨｪｨｨ04ｨ 02ｨｨｨｨ ｨ ｨｪ ｨｨｨ 0609 Candida, ｨｺ06ｨｰ ｨｨ ｨｰ ｨｺ ｨ ｨｰ ｨｬ ｨｪｨｨ07ｨｬ ｨｰ060906ｨｦ ｨｰｨｨ 0708ｨｨ 09ｨｪｨｨ0302ｨｪｨｪ06ｨｬ ｨｨｨｬｨｬｨｮｨｪｨｨｨｰ02ｨｰ ｨｰ06ｨｬｨｮ ｨｬ 07ｨ 02ｨｨ02ｨｪｨｰｨ ｨｬ ｨ 0405ｨ 06ｨ ｨｲ0709ｨｪ02ｨｪｨ 09ｨ 03ｨｪ0609ｨｰｨｹ ｨｨ 0708ｨ 09ｨｨ05ｨ ｨｮ010601ｨ 04ｨ ｨｰｨｹ06 08ｨｰｨ ｨ 08ｨｨｨｪ0002ｨ 05ｨｹｨｪ04ｨｦ ｨｺｨ ｨｪ01ｨｨ ｨ ｨｪｨｪｨｨｨｦ 0708ｨｨ04ｨｪｨ ｨｺ 0006 ﾁ ｨｨｨｪ0002ｨｺ02ｨｨｨｨ, ｨ ｨｪ0208ｨ 05ｨｨ04ｨ 02ｨｨ07- ｨｨｨｪ01ｨｨｨｺｨ ｨｰ0608, ｨｴｨ 06ｨｴｨｨｨｦ 08ｨ 0409ｨｨｨｰｨｨ ｨ. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, ｨｪ0206ｨ ｨｨｨｬ ｨｬ02ｨｪｨｪ ｨｪｨｨ02 ｨｨ 0502 ﾂ02ｨｪｨｨ02 ｨｺｨ ｨｪ01ｨｨ010604ｨ ｨｰｨｨ 08ｨｰｨ ｨｮ 0006 ﾁ ｨｨｨｪ00ｨｨ02ｨｨ080609ｨ ｨｪｨｪ ｨｰ0908ｨ ｨｴ02ｨｪｨｨ07 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｨ ｨ ｨｨ 0002ｨｪ0208ｨ 05ｨｨ04ｨ 02ｨｨｨｨ 0008ｨｨｨ ｨｺ060906ｨｦ ｨｨｨｪ0002ｨｺ02ｨｨｨｨ.

7 130606ｨｬ II. 0105ｨ 09ｨ ﾁ ｨ 08ｨ ｨ ｨ ｨｪ , ｨｨｨｰ , ｨｪｨｺ ｨｮ0909ｨｺｨ 07 ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺｨ 07 ｨ ｨｺｨ 0102ｨｬｨｨ ｨｨ070506ｨｬｨｪ ｨ 08ｨ ｨ ｨｪｨｨ07 00ｨｨｨｪ09ｨｺ, ｨ 08ｨｮ09ｨｹ 01ｨ ｨｨｨ ﾂｨ 09ｨｰ04ｨｬ 05ｨｰｨｨ ｨｨ ﾂ0209ｨｺｨｨｨｬ 00ｨ ｨｺｨｰ060806ｨｬ 06ｨｪｨｨ0106ｨｬｨｨｨｺ ｨ 08ｨｮ09ｨｨ ｨ 0405ｨｨ ｨｬｨ ｨｰ0600ｨｨｨｰ04, ｨｪｨ ｨｺ06ｨｰ ｨｨ ｨｪｨｨｨｨ ｨｬｨｨｨｺ ｨｨ ﾂ0209ｨｺ ｨｨ ｨ ｨｪｨｨ ｨｨ010601ｨｨ050609ｨｹ 98% ｨｮ ﾂｨ ｨｪｨｨ0106ｨｬｨｨｨｺ0604ｨ ｨｨ 09 05ｨｰｨｨｨｬ 09 ｨｺｨ ﾂ0209ｨｰ ｨｰｨｨ06ｨｰ080607ｨｪ ｨｰ09ｨ ﾂ02ｨｪｨｨ07 06ｨｪｨｨ0106ｨｬｨｨｨｺ ｨｰ02 ﾂ02ｨｪｨｨ ｨｪｨｨ ｨｰ ｨｪｨ 04ｨｪｨ ﾂｨ ｨｮｨｪ00ｨｨ09ｨｰｨ ｨｰｨｨｨｺ 0008ｨｨ ｨｮ05ｨｹ09ｨｨｨｪ. 01ｨ 04ｨｪｨ ﾂｨ 02ｨｬｨ ｨ ｨｺ060502ｨ ｨ 05ｨ 09ｨｹ 06ｨｰ ｨｰｨ ｨ 0502ｨｰ06ｨｺ 09 09ｨｮｨｰｨｺｨｨ ｨｨ 04ｨ 09ｨｨ090205ｨ 06ｨｰ 09ｨｰ020702ｨｪｨｨ ｨ 0302ｨｪｨｨ07 ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪ, ｨｪｨ 05ｨｨ ﾂｨｨ ｨｮｨｰ09ｨｰ09ｨｮ06ｨｴｨｨ01 04ｨ ｨ ｨ ｨｪｨｨ07 ｨｨ ｨｪ0609ｨｨｨｬ0609ｨｰｨｨ 0502 ﾂ02ｨｪｨｨ ｨｦ ｨｬ ｨ 08ｨ ｨｰ ｨｪｨ 04ｨｪｨ ﾂｨ 05ｨｨ ｨｪ0209ｨｪ06, 09ｨｰ060806ｨｦ ｪ ﾂ ｨｪｨｹ, ｨ 04ｨ ｨｰ02ｨｬ 2 08ｨ 04ｨ 09 ｨｪ ｨｰ08ｨ 09ｨｰｨ ｨｪｨｨ ｨｪ0600ｨｰ02ｨｦ. 0308ｨｨ 09ｨｮｨｰ06 ﾂｨｪ06ｨｦ ｨｰｨ ｨ 0502ｨｰｨｺｨｨ ｨ 08ｨ ｨｰ ｨｪｨ 04ｨｪｨ ﾂｨ 05ｨｨ ｨｪ0209ｨｪ ｨｹ ｨｨ ﾂ02ｨｪｨｨ07. 01ｨ ｨｮ ｨｨ ｨｮ05ｨｹ09ｨｨｨｪ06ｨｬ ｨ 0605ｨｹｨｪ04ｨｬ ｨｪｨ 04ｨｪｨ ﾂｨ 05ｨｨ 09ｨｨｨｰｨ ｨｬｨｨｨｪ04 08, 001, 006, 05, ｨｮ010608ｨ 0903ｨｨ080706ｨｴｨｨ ｨｰ09ｨ ｪ ｨｺ09ｨ ｨｪｨｰｨｨｨｪ0605ｨ ｨｪｨｨｨｺ06ｨｰｨｨｨｪｨ ｨｰ ｨｨ05ｨｨ 07ｨｨ080806ｨｺ09ｨ ｨｪ, 0700 ﾁ ｨｪｨ ｨｪｨｨ ﾂｨｪ ｨｨｨｬ07ｨ ｨｰｨｨ ﾂ0209ｨｺｨｨ02 00ｨ ｨｪ0005ｨｨｨｨ 07ｨ 08ｨ ｨｰ02ｨ 08ｨ 05ｨｹｨｪ06 ｨｨ05ｨｨ ｨｨｨｪ01ｨｮｨｺｨｰ06ｨｰ0208ｨｬｨｨ ｨｪｨｨ ﾂｨｪ06ｨｦ 06ｨ 05ｨ 09ｨｰｨｨ. 07 ﾂｨｨｨｰ0409ｨ 07 00ｨｮｨｪ00ｨｨ09ｨｰｨ ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｺｨｰ 0008ｨｨ ｨｮ05ｨｹ09ｨｨｨｪｨ, 06ｨ ｨｴ ﾂ02ｨｪｨｨ ﾂ02ｨｰｨ 05ｨｨ 09 ｨｬ0209ｨｰｨｪ04ｨｬｨｨ 0502 ﾂ02ｨｪｨｨ02ｨｬ ｨｰｨｪ ﾂ02ｨｪｨｨ02 09ｨｺ0506 ﾂｨ 0506 ｨｪｨ ｨｪｨｨ02 ｨｺ0208ｨ ｨｰ0605ｨｨｨｰｨｨ ﾂ0209ｨｺｨｨ ｨ 09ｨｰ040802ｨｦ ｨｨ ｨｮ06ｨｴ ﾂ02ｨｪｨｨ02 ｨｪ0600ｨｰ ｨ, ｨｺ ｨｨ01ｨｨｨｦｨｪ ｨｰ090506ｨｦｨｺｨｨ 0507ｨｨ010208ｨｬｨｨ09ｨ ｨｪｨ 05ｨ 0106ｨｪ0701 ｨｨ ｨ ｨｮ06ｨｴｨｨｨｬ 0502 ﾂ02ｨｪｨｨ02ｨｬ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ﾂ02ｨｪｨｨ02 ｨｪ0600ｨｰ02ｨｦ ｨｨ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｪｨ ﾂｨｨｨｪｨ 05ｨｨ 09 ｨｦ0601ｨｪ ｨｨｨｰ0409ｨ ｨｪｨｨ07 ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪ06ｨｺ ｨｨ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06 2, 5 ｨｨ 10%-ｨｪ06ｨｦ ｨｦ0601ｨｪ06ｨｦ ｨｪｨ 09ｨｰ06ｨｦｨｺ06ｨｦ 09 ｨｰ02 ﾂ02ｨｪｨｨ ｨｪ02ｨｦ. 01ｨ ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪｨｺｨｨ ｨ 09ｨｰ0408ｨｹ ｨｪｨ ｨｺ05ｨ ｨ 05ｨｨ ｨｮ0802ｨ 0705ｨ 09ｨｰ, ｨｨ040006ｨｰ ｨｪｨｪ04ｨｦ ｨｨ09ｨｨ: ｨｺｨ 08ｨ ｨ ｨｬｨｨ01ｨ ｪ 16 00, 05ｨ ｨｪ0605ｨｨｨｪｨ ｪ 14 00, ｨｪ06ｨｦ ｨｮｨｺ09ｨｮ09ｨｪ06ｨｦ ｨｺｨｨ090506ｨｰ04 ｪ 2 00, 07ｨ 08ｨ 0000ｨｨｨｪｨ ｪ 3 00 ｨｨ 01ｨｨ09ｨｰｨｨ0505ｨｨ080609ｨ ｨｪｨｪ06ｨｦ ｪ ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ ｨｪｨ ｨｺ05ｨ 01ｨｺｨｨ ｪ 5 09ｨｮｨｰ06ｨｺ ｨｪ07ｨｰｨｨ07 ｨｮ0802ｨ 0705ｨ 09ｨｰｨ ｨｨ050609ｨｹ ｨｮ01ｨ 0502ｨｪｨｨ02 08ｨ 04ｨｬ0700 ﾂ02ｨｪｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ ｨｪ0600ｨｰ020906ｨｦ 0705ｨ 09ｨｰｨｨｨｪｨｺｨｨ ｨｬｨ ｨｪｨｨｨｺ0608ｨｪ04ｨｬｨｨ ｨｴｨｨ07 ﾂｨｨｨｺｨ ｨｬｨｨ, ｨｮ06ｨｴ02ｨｦ ｨｦ0601ｨｪ06ｨｦ ｨｨｨｰｨｺ06ｨｦ 09 ｨｰ02 ﾂ02ｨｪｨｨ ｨｪ02ｨｦ ｨｨ ｨｪｨ ｨｪｨｨ02ｨｬ ｨｮ0802ｨ 0705ｨ 09ｨｰｨ ｨｪｨ 5 09ｨｮｨｰ06ｨｺ. 01ｨ ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪｨｺｨｨ 09ｨｰ0607 ｨｮ0802ｨ 0705ｨ 09ｨｰ ｨｪｨ ｨｺ05ｨ ｨ ｪ 5 08ｨ 04, ｨｪｨ ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪｨｺｨｨ ｨｺｨｨ09ｨｰ02ｨｦ ｪ 3 08ｨ 04ｨ ｨｪ02ｨｦ ｨｪｨ ｨｺ05ｨ 01ｨｺｨｨ ｨｨ ﾂｨｨ09ｨｰｨｺｨｨ ｨｪｨ ｨｪ0600ｨｰ ｨｰｨｹ ｨｰ08ｨ 09ｨｰｨ ｨｪｨｨ07 ｨｪ0600ｨｰ020906ｨｦ 0705ｨ 09ｨｰｨｨｨｪｨｺｨｨ 0005ｨ 04ｨｪ06ｨｦ 07ｨｨ0702ｨｰｨｺ06ｨｦ ｨｺｨ 07ｨ 05ｨｨ ｨｺｨ 0705ｨｨ 08ｨ 09ｨｰ090608ｨ, ｨｨｨｬ0206ｨｴ ｨｰｨ 09: 09ｨ 05ｨｨ02ｨｨ ｨｦ ｨｺｨｨ090506ｨｰ04 ｪ 7 00, ｨ 02ｨｪ0406ｨｦｨｪ06ｨｦ ｨｺｨｨ090506ｨｰ04 ｪ 3 00, ｨｮｨｺ09ｨｮ09ｨｪ06ｨｦ ｨｺｨｨ090506ｨｰ04 80% ｨｨ 0907ｨｨ08ｨｰｨ 05ｨｰｨｨ % ｨｨ 01ｨｨｨｬ02ｨｺ09ｨｨ01ｨ ｪ ﾁ ｨｺｨｮｨｪ ｨｪｨ ｨｪ020902ｨｪｨｨ07 08ｨ 09ｨｰ090608ｨ ｨｪ0600ｨｰ0209ｨｮ ｨ 09ｨｰｨｨｨｪｨｺｨｮ ﾂｨｨｨｴｨ 05ｨｨ. 00ｨｬ0209ｨｰ06 08ｨ 09ｨｰ090608ｨ ｨｪｨ ｨｪ06 ﾂｨｹ ｨｪｨ ｨｪ0600ｨｰ ｨ ｨｬ0603ｨｪ06 ｨｪｨ ｨｺ05ｨ ｨ ｨｰｨｹ ｨｬｨ 04ｨｹ ｨｮ06ｨｴ ｨｰｨ 09ｨ : 09ｨ 05ｨｨ02ｨｨ ｨｦ ｨｨ ｨ 02ｨｪ0406ｨｦｨｪ06ｨｦ ｨｺｨｨ090506ｨｰ , 07ｨ 08ｨ 0000ｨｨｨｪｨ ｨｨ ｨｪ02 ﾂｨｪ ｨｬｨ 0905ｨ ｪ ｨｨ 09ｨｺ09ｨ ｨｬ0604ｨｪ06 ｪ 00ｨｨ070208ｨｰ080600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨｬ02 ｨｬｨｨｨｺ0604ｨ 09ｨｰ0607 ｨｨ ｨｺｨｨ09ｨｰ02ｨｦ ｨｨ05 ｨｨ0601ｨｪｨｮ ｨｨｨｰｨｺｨｮ 0507ｨｨ010208ｨｬｨｨ09ｨ, ｨ 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨｺ0208ｨ ｨｰ0605ｨｨｨｰｨｨ ﾂ0209ｨｺ ｨｰ09ｨ ｨｨ ｨｹ040609ｨ 05ｨｨ 20%-ｨｪ04ｨｦ ｨ 02ｨｪ0406ｨｦｨｪ06 ｪ 09ｨ 05ｨｨ02ｨｨ ｨｦ ｨｺ ｨｨｨｦ, ｨｺ06ｨｰ060804ｨｦ ｨｪｨ ｨｪ0609ｨｨ05ｨｨ ｨｪ02ｨｰ060509ｨｰ04ｨｬ ｨｬ ｨｪｨ ｨｺ0603ｨｮ 1 08ｨ ｨｪｨｹ ｨｪ02 ｨ ｨｪ02ｨｦ ｨｪｨ ｨｺ0603ｨｮ ｨｺｨｨ09ｨｰ02ｨｦ ｨｨ ｨｪ02ｨｦ ｨｪｨ ｨｺ0603ｨｮ 09ｨｰ ｨｺ06ｨｪ ﾂｨ ｨｪｨｨ02ｨｬ 06ｨｰ090506ｨｦｨｺｨｨ 09 ﾂｨｨｨｰｨ 05ｨｨ ｨｬ06ｨｬ02ｨｪｨｰ ｨｪ ｨｰ09ｨｰｨ 09ｨ ｨｪｨｨ ｨｨ010208ｨｬｨｨ09ｨ 09 06ｨ 05ｨ 09ｨｰｨｨ 0707ｨｰ06ｨｺ ｨｨ ｨｺ ｨｪ ｨｺ06-

8 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ 09ｨｰ02ｨｦ ｨｪｨ 09ｨｰ0607ｨ 01 ｨｨ 09 06ｨ 05ｨ 09ｨｰｨｨ 00ｨｨ0706ｨｰ02ｨｪｨ 08ｨ ｨｨ ｨｺ ｨｰｨｪ0401 ｨｺ0609ｨｰ02ｨｦ ｨｪｨ ｨｺｨｨ09ｨｰ ｨｨ ｨｨ0102ｨ 05ｨｹｨｪ06ｨｦ 06ｨｰ090506ｨｦｨｺ ｨｨ010208ｨｬｨｨ09 06ｨｰ09ｨｰｨ 02ｨｰ 0705ｨ 09ｨｰ06ｨｬ 09 09ｨｨ ﾂｨ ｨｰ06ｨｺ03 ｨｨ 00ｨｪ0609ｨｺ ｨｨｨｺｨ 02ｨｨｨｨ ｨｺ ｨｨ07 09 ｨｬ020307ｨ 05ｨｹ ｨｺ05ｨ 01ｨｺｨｨ ｨｨｨｰ0907 ｨｪ02 ｨ ｨ ｨｨ 0507ｨｨ010208ｨｬｨｨ09 06ｨｰ090506ｨｨ ｨｪ ｨｪ0609ｨｰｨｹ06 ｨｨ 06ｨｰ09ｨｰｨ 02ｨｰ 09 ｨｰ08ｨｮ0106ｨｬ, ｨｪｨ 04ｨｪｨ ﾂｨ 06ｨｰ ｨｬ0405ｨｹｨｪ06 ｪ ｨ ｨｪｨｪ06 ﾂｨｺｨｨ ｨｨ 06ｨｰ090506ｨｨ0903ｨｨｨｦ ｨｨ010208ｨｬｨｨ ｨｰ ｨｪ06 06ｨ ｨ 06ｨｰ ｨ 05ｨｹｨｪ02ｨｦ0302ｨｬ ｨｺ0603ｨｮ 05ｨ 0106ｨｪ02ｨｦ ｨｨ ｨｰ090506ｨｦｨｺｨｨ 09 ｨｰ02 ﾂ02ｨｪｨｨ02 ｨｬ ｨ 09ｨｬｨ ｨ 06ｨｰ 5% ｨｨ0601ｨｪ06ｨｦ ｨｪｨ 09ｨｰ06ｨｦｨｺ06ｨｦ ｨｨ 3%-ｨｪ06ｨｦ ｨ 02ｨｪ0406ｨｦｨｪ06 ｪ 09ｨ 05ｨｨ02ｨｨ ｨｦ ｨｬｨ 04ｨｹ06. 01ｨ ｨ ｨｪｨｨ02 04ｨ 987 ｨ 0605ｨｹｨｪ04ｨｬｨｨ, ｨｮ ﾂｨｨ0903ｨｨｨｬｨｨ 0502 ﾂ02ｨｪｨｨ ｨｰ06ｨｦ ｨｬ02ｨｰ0601ｨｨｨｺ02, ｨｨ ｨｰ ｨｨｨｰｨｹ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｮ 86% ｨｹ040609ｨ ｨｪｨｨ02 ｨ ｨｺｨｰｨｨ09ｨｪ ｨｬ02ｨｪｨｪ0401 ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ0609, ｨｪｨ 0708ｨｨｨｬ0208, ｨｪｨｨ040608ｨ 05ｨ, ｨｬ060302ｨｰ ｨｨｨｰｨｹ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 0502 ﾂ02ｨｪｨｨ07. 05ｨｨ09ｨｰ02ｨｬｨｪ0402 ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺｨｨ ｨｰｨｨ07ｨ ｨｰ0208ｨ ｨｨｨｪｨ 00ｨｨｨｪｨ ｨｨ ｨｨｨｰ08ｨ ｨｺ06ｨｪｨ ｨ ｨｪ02 ｨｰ0802ｨ ｨｮ06ｨｰ ｨｪｨｨ07 ｨｬ0209ｨｰｨｪ ﾂ02ｨｪｨｨ07, ｨｪ ｨｺｨ 0609ｨｰｨ 06ｨｰ0907 ｨｬｨ ｨｰｨｮ07ｨｪ04ｨｬｨｨ ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ09ｨ ｨｪｨ ｨｪｨｨ07 ｨｨ04 ｪ 04ｨ ｨｺ06ｨｦ 09ｨｰ06ｨｨｨｬ0609ｨｰｨｨ, ｨｨ 09 ﾂ02ｨｬ ｨ 00ｨ 02ｨｬｨ 07 ｨｪｨ ｨｬｨｨ ｨｬ02ｨｰ0601ｨ 0502 ﾂ02ｨｪｨｨ07 06ｨｪｨｨ0106ｨｬｨｨｨｺ ｨ 02ｨｰ 09 ｨｮ ｨｬ ｨｨ ｨｹ040609ｨ ｨｰｨｹ ｨｺ0603ｨｪ06 ｪ 0902ｨｪ ｨｨ ﾂ0209ｨｺｨｨ01 ｨｮ ﾂ ｨｪｨｨ ｨ 08ｨｮ09ｨｨ. COMBINATION THERAPY IN ONYCHOMYCOSIS MANAGEMENT Baran E. Department of Dermatology and Venerology ｨ 09, ｨｹ03ｨ Introduction: A combined approach to onychomycosis management is becoming more and more popular. The complementarity of both antifungal activity and topical and oral administration of antifungal agents seems to be the most rational. Objective: Assessment of the efficacy, tolerability and patient satisfaction of amorolfine 5% nail lacquer (Loceryl06) combined with an oral antifungal in patients with toenail onychomycosis with matrix involvement. Patients and methods: A multicentre study of 218 patients was conducted for 12 months. All patients received both amorolfine lacquer once weekly for 12 months and an oral antifungal of researcher ｯs choice: either terbinafine 250 mg once per day for 3 months (AT group), itraconazole 200 mg twice per day in pulse therapy for 3 months (AI group) or fluconazole 300 mg once per week for 6 months (AF group).oral pentoxiphyline 400 mg twice per day for three months was optional. Global cure has been defined as remaining of maximum 10% of initial lesions and negative culture examination. Tolerability was assessed for the topical and oral antifungal separate. Patient ｯs satisfaction score was based on the opinion of the individual patients. Results: There was a 77,06% of global cure independently of the oral antifungal used (76,25% in the AT group, 79,41% in the AI group and 71,43% in the AF

9 130606ｨｬ II. 0105ｨ 09ｨ 1 9 group). There was no higher efficacy noted in patients receiving pentoxi phyline. Both topical amorolfine and the oral antifungals were very well tolerated. The most importantly, the majority of patients were satisfied of the treatment. Conclusions: The combination of topical amorolfine with oral antifungal (terbinafine, itraconazole or fluconazole) is an effective and very well tolerated onychomycosis therapy ﾁ ﾁ ( ) ｨ ｨｰｨｺｨ , 01ｨ 07ｨ 0802ｨｪｨｺ , ｨ , 0609ｨ ｨｪ ｨ ｨ ｨｬｨ ｨｰ060902ｨｪ ｨｨｨｨ , ｨｪ01ｨｨ0907ｨ ｨｪ ｨｺ09ｨ ｨｹｨｪ06ｨｦ ｨｰ, 09 01ｨ 09ｨｪ0609ｨｰｨｹ06 04ｨ ｨ ｨ ｨｪｨｨ07 6 ｨｬ , ｨｪｨ ｨ ｨ ｨｰ02 ﾂ02ｨｪｨｨ ｨｬ ｨｨｨ 00ｨｪ060406ｨｬ: 04ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪｨ ｨｬｨ 08ｨｮｨ ｨｨｨｰｨｨｨｨ ｨｺ0603ｨｨ, ｨｺ06ｨｰ060804ｨｦ ｨ ｨｰ ｨｪ 05ｨ ｨ 0608ｨ ｨｰ0608ｨｪ ﾂｨｨｨｰ0409ｨ 07 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ0609ｨｰｨｹ ｨ : 05ｨｨ0206, ｨｰｨｮ050609ｨｨｨｴ02, ｨｪｨｨ02 ｨｨ ｨｪｨｨ03ｨｪｨｨ02 ｨｺ06ｨｪ02 ﾂｨｪ0609ｨｰｨｨ, ｪ ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨ ｨｰ0208ｨ 07ｨｨ07 09ｨｨ09ｨｰ02ｨｬｨｪ04ｨｬ 06ｨｰ02 ﾂ0209ｨｰ0902ｨｪｨｪ04ｨｬ ｨ 08ｨ ｨｰ06ｨｬ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ06ｨｬ ｨｺ0609ｨｰｨ ｨｰ06ｨｬ (080506ｨｺ06ｨｪｨ ｨｬ), 06ｨｰｨｪ060907ｨｴ02ｨｬｨｮ0907 ｨｺ ｨｺ05ｨ 0909ｨｮ ｨｰ08ｨｨｨ ｨｹｨｪ ｨｰｨｨ ｨｨｨ ｨｺ ｨｰ ｨｪｨ 0302ｨｬ ｨｪｨ ｨ ｨｪｨｨｨｨ ｨ 0605ｨｹｨｪ06ｨｦ ｨｬｨｮ03 ﾂｨｨｨｪｨ ｨｰ, 0708ｨｨｨｪｨｨｨｬｨ ｨｺ0609ｨｰｨ ｨｰ ｨｬ ｨ ｨｪｨｹ ｨｪ0209ｨｪ06 09 ｨｰ02 ﾂ02ｨｪｨｨ ｨｪ02ｨｦ ｨｪ0609ｨｨｨｬ0609ｨｰｨｹ 0502 ﾂ02ｨｪｨｨ07 ｨ 0405ｨ ｨｦ, ｨｺｨ ｨｺｨｨ01-05ｨｨｨ ｨｪ02ｨｪｨｨｨｦ ｨｪ ｨｪ ｨｪｨ 3-ｨｦ 0102ｨｪｨｹ 0502 ﾂ02ｨｪｨｨ ｨ 08ｨ ｨｰ06ｨｬ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ06ｨｬ ｨｨ09 ﾂ ｨｮ01, 0508ｨｨｨｰ02ｨｬｨ ｨｰ0604ｨｪ ﾂｨ 00ｨｨ 09ｨｰｨ 05ｨｨ ｨ ｨｪ0202, ｨｬ0205ｨｺ060705ｨ 09ｨｰｨｨｨｪ ﾂｨ ｨｰ0602 ｨｨ 06ｨｰ08ｨｮｨ 0209ｨｨ01ｨｪ ｨｮ0302ｨｪｨｨ02 09 ｨｪｨｨ ｨｪｨ - ﾂｨｨｨｰ0205ｨｹｨｪ06ｨｦ 09ｨｰ020702ｨｪｨｨ ｨｮｨｬ02ｨｪｨｹ03ｨｨ050609ｨｹ; ｨｪｨ 05ｨ 0106ｨｪ0701 ｨｺｨｨ09ｨｰ02ｨｦ ｨｺ0603ｨ 09ｨｰｨ 05ｨ ｨｬ0700 ﾂ02, 0505ｨ 09ｨｰｨｨ ﾂｨｪ0202, 0708ｨｨ06ｨ ｨ ｨｦ 06ｨｰｨｰ02ｨｪ06ｨｺ 09ｨｬ0209ｨｰ ｨ ｨｰ060006, ｨｰ0802ｨｴｨｨｨｪ ｨｪ0609ｨｪ06ｨｬ 04ｨ 0507ｨｨｨｰ0205ｨｨ04ｨｨ080609ｨ 05ｨｨ09ｨｹ, ｨｮ0302ｨｪｨｨ02 ｨｰｨ ｨｺ ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06 ｨｮｨｬ02ｨｪｨｹ03ｨｨ050609ｨｹ. 08 ｨｺ06ｨｪ02ｨｮ 2-01 ｨｪ ｨｹｨｪ ｨｺｨｮ0809ｨ 0502 ﾂ02ｨｪｨｨ ｨ ｨｪｨｨ07 ｨｪｨ ｨｺ ｨｨ02ｨ, ｨｰｨｮ050609ｨｨｨｴｨ ｨｨ ｨｺ06ｨｪ02 ﾂｨｪ0609ｨｰ02ｨｦ 06ｨｺ06ｨｪ ﾂｨ ｨｰ0205ｨｹｨｪ ｨ 0502ｨｺ05ｨｨ, 0609ｨｰｨ 05ｨ 09ｨｹ 05ｨｨ03ｨｹ ｨｮｨｬ020802ｨｪｨｪｨ 07 04ｨ 09ｨｰ06ｨｦｨｪｨ ｨｨｨｰ02ｨｬｨ 09 08ｨ 04ｨｬ04ｨｰ04ｨｬｨｨ 0008ｨ ｨｪｨｨ02ｨ ｨｬｨｨ 09 07ｨ ｨ ｨｪｨｪ ｨｺ05ｨ 01ｨｺｨ 01 ｨｨ ｨｪｨ ｨｪ0701; ｨｪｨ 05ｨ 0106ｨｪ0701 ｨｺｨｨ09ｨｰ02ｨｦ ｨｨｨｪ00ｨｨ05ｨｹｨｰ08ｨ 02ｨｨｨｨ ｨｨ ｨｰ0802ｨｴｨｨｨｪ ｨｪ02 ｨ , ｨｪ ｨ ｨｪ ｨｹ ｨｮｨｬ020802ｨｪｨｪ0602 ｨｬ0205ｨｺ060705ｨ 09ｨｰｨｨｨｪ ﾂｨ ｨｰ ｨｮ0302ｨｪｨｨ02. 09ｨ ｨ 0608ｨ ｨｰ0608ｨｪ06: 09 ｨ ｨｪｨ 05ｨｨ ｨｨｨ 04 ｨｪ02 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ ｨｰｨｬ02ｨｪ ｨ 08ｨ ｨｰｨ, ｨｪｨ 0006ｨｪ ｨ 06ｨｴ ｨ ｨ ｨｪｨｨｨｦ, 06ｨｰｨｬ02 ﾂ02ｨｪ ｨｬ02ｨｪｨｪ ｨｪｨｨ02 ｨｮｨｬ020802ｨｪｨｪ ｨｮ01ｨ ｨｪｨ ｨｪ0701 ｨｨ ｨ ｨ ｨｪ04ｨｦ ｨ ｨｪｨｨｨｦ ｨｨ 04ｨｮ01ｨ ｨｪｨ 09ｨｰｨｮ07ｨｨ05 ﾂ ,5 ｨｬ ｨ ｨｺ06ｨｪ ﾂｨ ｨｪｨｨ07 ｨｺｨｮ0809ｨ 0502 ﾂ02ｨｪｨｨ ｨｺ0609ｨｰｨ ｨｰ06ｨｬ 09 ｨｺｨｮ ｨｦ ｨｬ00. 09ｨ ｨ 0608ｨ ｨｰ0608ｨｪ06: ｨ ｨｪｨ 05ｨｨ0404 ｨｪｨ 0008ｨｨｨ ｨｰｨ 09ｨ 05ｨｨ09ｨｹ 09ｨｰ06ｨｦｨｺ06 06ｨｰ08ｨｨ02ｨ ｨｰ0205ｨｹｨｪ04ｨｬｨｨ ｨｪｨ ｨｬ ｨｰ070302ｨｪｨｨｨｨ 0502 ﾂ02ｨｪｨｨ07 ｨｨ ｨｪｨ ｨ ｨｪｨｨ07. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, 0708ｨｨ 0502 ﾂ02ｨｪｨｨｨｨ 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ0401 ｨｬｨｨｨｺ ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ, 0706ｨｺｨ 04ｨ ｨｪ ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 09ｨｨ09ｨｰ02ｨｬｨｪ0401

10 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ ｨ 08ｨ ｨｰ0609 ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ ｨｨ09ｨｰ02ｨｬｨｪ04ｨｦ 06ｨｰ02 ﾂ0209ｨｰ0902ｨｪｨｪ04ｨｦ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ ｨｺ0609ｨｰｨ ｨｰ (080506ｨｺ06ｨｪｨ ), 06ｨｰｨｪ060907ｨｴｨｨｨｦ0907 ｨｺ ｨｺ05ｨ 0909ｨｮ ｨｰ08ｨｨｨ ｨｹｨｪ ｨｰｨｨ ｨｨｨ ｨｺ ｨ 08ｨ ｨｰ0609, ｨｪ 03ｨｨ0802 ｨｨ ｨｹ040609ｨ ｨｰｨｹ ｨ ｨｺｨｰｨｨｨｺ ｨｬｨ ｨｰ ｨ ﾂ02ｨｪｨｨ07 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ0401 ｨｬｨｨｨｺ ﾁ ｨ ｨｰｨｺｨ , 01ｨ 07ｨ 0802ｨｪｨｺ , 0406ｨｬｨｨｨｪ , ｨ , ｨ ｨ , ｨｨｨｬ02ｨｪｨｨ ｨｪｨｺ ｨｺ09ｨ 00ｨｨｨｺ ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｰ ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ06ｨｦ 07ｨ ｨｰ ｨｨ02ｨｦ ﾂ ｨｺｨ. 02ｨｪｨｨ ｨｰｨ ｨｰ 06ｨｺ % 09 06ｨ ｨｴ02ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ ｨ ｨ ｨ 02ｨｬ0609ｨｰｨｨ ｨｬｨ ｨｰ0604ｨ ｨｬｨｨ, ｨｰ06ｨｬｨｮ 09ｨｪ ｨｪｨｨ ﾂ02ｨ ｨｪｨｮ ｨ ｨｺｨｰｨｨｨｺｨｮ ｨｪ ｨｬ ｨｰ0208ｨ 07ｨｨｨｨ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺｨ ｨｬｨｨ ｨｺｨ ｨｺ 09ｨｨ09ｨｰ02ｨｬｨｪ060006, ｨｰｨ ｨｺ ｨｨ ｨｬ0209ｨｰｨｪ ｨｨｨｬ02ｨｪ02ｨｪｨｨ ｨｰｨ ｨｰ0907 ﾂ ﾂｨ ｨｦｨｪ06 ｨ ｨｺｨｰｨｮｨ 05ｨｹｨｪ06ｨｦ 04ｨ 01ｨ ﾂ02ｨｦ ｨｹ06 ｨｨ04ｨｮ ﾂ02ｨｪｨｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 06ｨｰ02 ﾂ0209ｨｰ0902ｨｪｨｪ ｨｺ0609ｨｰｨ ｨｰｨ (0805ｨｮｨｺ06ｨｪｨ ) 09 ｨｰ0208ｨ 07ｨｨｨｨ 08ｨｮｨ ｨｨｨｰｨｨｨｨ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｪｨ ｨ ｨ 05ｨｨ 48 ｨ 0605ｨｹｨｪ ｨ 09ｨｰ ｨｰ (0302ｨｪｨｴｨｨｨｪ ｪ 31, ｨｬｨｮ03 ﾂｨｨｨｪ ｪ 17) ｨ 0605ｨｹｨｪ0401 ｨ 0405ｨ ｨ 0302ｨｪｨ ｨｰ0605ｨｹｨｺ06 ｨｺ0603ｨ 09ｨｰ0607, ｨｬ020307ｨ 05ｨｹ ｨｺ05ｨ 0106ｨｺ 09ｨｰ0607, ｪ 09 07ｨ ｨｰ ｨｨ- ﾂ0209ｨｺｨｨｨｦ ｨ 0405ｨ ﾂ02ｨｪｨ ｨｺ0603ｨ 07ｨ ｨｺ05ｨ 0106ｨｺ ｪ 0002ｨｪ0208ｨ 05ｨｨ040609ｨ ｨｪｨｪｨ ｨｬｨ 04ｨ ｨ ｨ ｨｪｨｨ ｨ 0605ｨｹｨｪ0401 ｨｪｨ ｨ ｨ 05ｨ 09ｨｹ 01ｨｨ0900ｨｨ010806ｨｰｨｨ ﾂ0209ｨｺｨ ｨｬｨ 08ｨｮｨ ｨｨｨｰｨｨｨｨ, ｨｮ 0609ｨｰｨ 05ｨｹｨｪ0401 ｪ ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ04ｨｦ 00ｨｨ070208ｨｺ0208ｨ ｨｰ0604 ｨｨ ｨｬｨｮｨｺ0609ｨｨ01ｨｪ ｨｮ0302ｨｪｨｨ02. 00ｨ 03ｨｪ06 06ｨｰｨｬ02ｨｰｨｨｨｰｨｹ, ﾂｨｰ ｨｨ ｨ 0302ｨｪｨｨｨｨ ｨｺ0603ｨｨ 07ｨ ｨｺ05ｨ 0106ｨｺ, ｨ ｨｰｨ ｨｺ ｨｨ 0002ｨｪ0208ｨ 05ｨｨ040609ｨ ｨｪｨｪ06ｨｦ ｨｬ02 08ｨｮｨ ｨｨｨｰｨｨｨｨ 07ｨ ｨｰ ｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｪｨ ｨｺ ｨ ｨ 00ｨ ｨｨｨｬｨｬ02ｨｰ08ｨｨ ﾂｨｪ06. 02ｨ 09ｨｪ0609ｨｰｨｹ 04ｨ ｨ ｨ ｨｪｨｨ ｨｰｨ ｨ 06ｨｰ 2 ｨｪ ｨｹ 0106 ｨｪ0209ｨｺ0605ｨｹｨｺｨｨ ｨｰ. 9 ｨ 0605ｨｹｨｪ ｨｪ ｨｬ02ｨｪｨｪ06 09ｨｰ08ｨ 01ｨ 05ｨｨ ｨｪｨｨ ﾂ0209ｨｺ06ｨｦ 05ｨｺ0402ｨｬ06ｨｦ, 5 ｪ ｨｨｨ 0406ｨｬ, 3 ｪ ｨｺ08ｨ 09ｨｪ04ｨｬ ｨｺｨｨｨｬ 05ｨｨ03ｨ 02ｨｬ ｨ 0605ｨｹｨｪ ｨｪ0106ｨｺ08ｨｨｨｪ ｨｬ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪ 09ｨ 01ｨ 08ｨｪ04ｨｦ 01ｨｨｨ ｨ 02ｨｰ. 12 ｨ 0605ｨｹｨｪ ｨｬ ﾂ02ｨｪｨｨ07 08ｨｮｨ ｨｨｨｰｨｨｨｨ ｨｨ ｨｹ040609ｨ 05ｨｨ 08ｨ 0405ｨｨ ﾂｨｪ0402 ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨ ﾂ0209ｨｺｨｨ02 ｨｬｨ 04ｨｨ ｨｬ02ｨｪｨｪ04ｨｬ ｨｮ ｨｬ ｨ 0605ｨｹｨｪ ｨｨ ｨｬｨｨｨｺ080609ｨｺ0607ｨｨ ﾂ0209ｨｺ06ｨｬ ｨｨ ｨ ｨｪｨｨｨｨ ﾂｨ ｨ 0302ｨｪｨｨ07 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ ｨｬｨｨ020205ｨｨｨｦ 0008ｨｨｨ ｨ ｨ 0605ｨｹｨｪ ｨｨ ｨｺｨｮ05ｨｹｨｰｨｮ08ｨ 05ｨｹｨｪ06ｨｬ ｨｨ ｨ ｨｪｨｨｨｨ 06ｨｰｨｬ02 ﾂｨ ｨｰ Trichophyton rubrum ｨｺ0609ｨｰｨ ｨｰ ｨｪｨ 04ｨｪｨ ﾂｨ 05ｨｨ ｨｬ ｨ ｨｪｨｹ, ｨｰ02 ﾂ02ｨｪｨｨ ｨｪ ｨｹ ｨｬ02 ｨｰ060006, ｨｪｨ 03ｨｨｨｬ ｨｪｨ ｨ ｨｪｨｨ02ｨｬ ｨｪｨ ｨｨ050609ｨｹ 65 ｨｬｨｮ03 ﾂｨｨｨｪ, ｨ 0605ｨｹｨｪ0401 ｨｺｨ ｨｪ01ｨｨ010604ｨｪ04ｨｬ ｨ ｨ 05ｨ ｨｪ ｨｰｨｨｨｰ06ｨｬ ｨ 09ｨｰ ｨｰ ｨｪｨｨ ｨｰ0806ｨｦ ｨｬ06ｨｦ (0208) 04ｨ ｨ ｨ ｨｪｨｨ07, ｨｺｨｮ0809ｨ ｨ ｨｪｨｰｨｨｨ ｨｨ06ｨｰｨｨｨｺ06ｨｰ0208ｨ 07ｨｨｨｨ ｨ ｨｨ ｨｪｨｨ ﾂ0209ｨｺ06ｨｦ ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴ02ｨｦ ｨｬ06ｨｦ (090408) ｪ 36 ﾂ ｨｺ ｨ 02ｨｨ02ｨｪｨｰ ｨ ｨ 05ｨ ｨｪ ｨｰｨｨｨｰｨ ｨ 0405ｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ04 08ｨ 0405ｨｨ ﾂｨｪ0402 ｨｨｨｪ0002ｨｺ02ｨｨ06ｨｪｨｪ ｨ 05ｨｨｨｰ0205ｨｹｨｪ ｨ ｨ ｨ ｨｪｨｨ07 ｨｮ ｨｪｨｨｨｰｨ 05ｨｹｨｪ ｨｰ08ｨ ｨｺｨｰｨ (02ｨｨ09ｨｰｨｨｨｰ04, ｨｮ0802ｨｰ ｨｰｨ ｨｰｨｨｨｰ04, ｨｰｨ ｨｰ ｨｨｨｺｨｮ05ｨｨｨｰ04, 0507ｨｨ01ｨｨ01ｨｨｨｬｨｨｨｰ04), ｨｮ 6 ﾂ ｨｺ 05ｨｰ06ｨｦ 0008ｨｮ ｨｪ0106ｨｺ08ｨｨｨｪ ｨｬ ｨｪ 09ｨ 01ｨ 08ｨｪ04ｨｦ 01ｨｨｨ ｨ 02ｨｰ ｨ 0605ｨｹｨｪ ｨｺ06ｨ ｨ ｨｺ0603ｨｨ ｨｺｨｨ ｨｨ

11 130606ｨｬ II. 0105ｨ 09ｨ 1 11 ｨｺ08ｨ ｨｦｨｪ02ｨｦ ｨｰｨｨ ﾂ0502ｨｪｨ 0708ｨｨ ｨｬｨｨｨｺ080609ｨｺ0607ｨｨ ﾂ0209ｨｺ06ｨｬ ｨｨ ｨ ｨｪｨｨｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ ｨｨｨ ｨ Candida ｨｺ0609ｨｰｨ ｨｰ ｨｪｨ 04ｨｪｨ ﾂｨ 05ｨｨ ｨｮ06ｨｴ02ｨｦ ｨｬ02: ｨｪｨｹ ｪ 150 ｨｬ00 09ｨｪｨｮｨｰ08ｨｹ 0601ｨｪ06ｨｺ08ｨ ｨｰｨｪ06, ｨｪｨｹ 0502 ﾂ02ｨｪｨｨ07 ｪ ｨｬ ｨ ｨｮｨｰｨｺｨｨ ｨｪ0609ｨｨｨｬ0609ｨｰｨｹ ｨｺ0609ｨｰｨ ｨｰｨ ｨｮ ｨ 02ｨｨ02ｨｪｨｰ ｨｮｨ ｨｨｨｰｨｨ02ｨｦ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｨ ｨｺｨ ｨｪ01ｨｨ010604ｨｪ04ｨｬ ｨ ｨ 05ｨ ｨｪ ｨｰｨｨｨｰ06ｨｬ ｨ 0405ｨ ｨｦ ｨ 0302ｨｪｨｪ ｨ 06 ﾂｨｪ ｨｪｨｨｨｦ 0708ｨｨ ｨｨ02ｨｬ02 ｨｮ ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ09ｨ 07ｨ 02ｨｨ02ｨｪｨｰ0609 ｨｪ02 06ｨｰｨｬ02 ﾂｨ ｨｹ. 0201ｨｪｨ ｨｺ06, ｨｮ 06ｨｰ010205ｨｹｨｪ0401 ｨ 0605ｨｹｨｪ ｨｨ02ｨｬｨ ｨ 08ｨ ｨｰｨ ｨｪｨ ｨ ｨ 05ｨｨ09ｨｹ ｨｪｨｨ07 01ｨｨ09ｨｺ06ｨｬ000608ｨｰｨ ｨｰ060806ｨｪ ｨ ｨｪ ｨｨ0102 ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06ｨｦ ｨｰ0603ｨｪ06ｨｰ04, ﾂｨｮ0909ｨｰ09ｨ ｨｰ ｨｰｨｨ ｨ ｨｰ06ｨ ｨｨ05ｨｨｨ 08ｨｪ06ｨｦ 0406ｨｪ02. 07ｨｺｨ 04ｨ ｨｪｨｪ ｨ 06 ﾂｨｪ ｨｪｨｨ07 ｨｨ09 ﾂ0204ｨ 05ｨｨ 0907ｨｮ09ｨｰ07 1,5-2 ﾂｨ 09ｨ ｨｨ02ｨｬｨ ｨｺ0609ｨｰｨ ｨｰｨ ｨｨ ｨｪ02 ｨｰ0802ｨ 0609ｨ 05ｨｨ ｨｰｨｬ02ｨｪ ｨｮ05ｨｹｨｰｨ ｨｰ ｨｪｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ ｨｮ ｨｪｨ ｨ ｨ 02ｨｬ ｨ 02ｨｨ02ｨｪｨｰ ｨｮｨ ｨｨｨｰｨｨ02ｨｦ ｨｨ ｨｺｨ ｨｪ01ｨｨ ｨｬ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨ ｨｰｨｨ00ｨｪｨｮｨｰ06 ｨｺ05ｨｨｨｪｨｨｨｺ06-05ｨｰｨｨ ｨｨ- ﾂ0209ｨｺ0602 ｨｨ ﾂ02ｨｪｨｨ02. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, ｨ 08ｨ ｨｰ ｨｺ0609ｨｰｨ ｨｰ ｨｰ ｨｺｨｰｨｨ09ｨｪ04ｨｬ ｨｰ0906ｨｬ 0502 ﾂ02ｨｪｨｨ07 08ｨｮｨ ｨｨｨｰｨｨｨｨ 0005ｨ 01ｨｺ06ｨｦ ｨｺ0603ｨｨ ｨｨ ｨｺｨ ｨｪ01ｨｨ010604ｨｪ ｨ 0302ｨｪｨｨｨｦ ｨｺ0603ｨｨ ﾂ0502ｨｪｨ ｨ ｨｰｨｺｨ , ｨ ｨ ｨｬｨ ｨｰ060902ｨｪ ｨｨｨｨ ｨｺ09ｨ ｨｪｨ 03ｨｨｨｬ ｨｪｨ ｨ ｨｪｨｨ02ｨｬ ｨｪｨ ｨｨ050609ｨｹ 495 ｨ 0605ｨｹｨｪ ｨｨｨ 0406ｨｬ (0302ｨｪｨｴｨｨｨｪ ｪ 254, ｨｬｨｮ03 ﾂｨｨｨｪ ｪ 241) ｨ 0405ｨｨ ｨｪ04 06ｨｪｨｨ010601ｨｨ09ｨｰ080600ｨｨｨｨ, ｨｰｨ ｨｪｨｪ ｨｪ0600ｨｰ020904ｨｬ 00ｨｨ070208ｨｺ0208ｨ ｨｰ060406ｨｬ ﾂｨ 09ｨｰｨｨ ﾂｨｪ04ｨｬ ｨｨ05ｨｨ ｨｰ06ｨｰｨ 05ｨｹｨｪ04ｨｬ, ｨ ｨｰｨ ｨｺ ｨｪｨｨ010605ｨｨ04ｨｨ0906ｨｬ). 0308ｨｨ 05ｨｰ06ｨｬ 01ｨｨｨ 00ｨｪ ｨｪｨｨ0106ｨｬｨｨｨｺ0604 ｨ ｨｰ ｨｪ 05ｨ ｨ 0608ｨ ｨｰ0608ｨｪ ｨｮ ﾂｨ 0701, ﾂｨｰ ｨｰｨ 09ｨｨ % ｨｮ ｨ 0605ｨｹｨｪ ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪｨｪ04ｨｬ 06ｨｪｨｨ0106ｨｬｨｨｨｺ060406ｨｬ 06ｨｰｨｬ02 ﾂｨ ｨｹ ｨ ｨｰ ｨｰ02 ﾂ02ｨｪｨｨ ｨｨｨ 04ｨ 09 ﾂｨ 09ｨｰ04ｨｬｨｨ 06ｨ 0609ｨｰ0802ｨｪｨｨ07ｨｬｨｨ, ｨ 06ｨｴ ｨｰｨｨ ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ ｨｨ ｨｬ0209ｨｰｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ ｨｨ04 ｨｪｨｨ01 ｨ ｨｪ ｨｨｨ ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨ 08ｨｰ08ｨｨｨｰ, ｨｮ 0601ｨｪ ｪ ｨｨ09ｨｰ ｨ 0502ｨｪｨｨ ｨｹｨｪ ｨｪｨｨ0106ｨｬｨｨｨｺ060406ｨｬ ｨ 0405ｨｨ 08ｨ 04ｨ ｨｨｨｰ04 ｨｪｨ ｨｰ08ｨｨ 0008ｨｮ ｨｮ0707ｨ (89 ﾂ ｨｺ) ｨｮ ﾂｨｨ05ｨｨ 0502 ﾂ02ｨｪｨｨ02 09ｨｨ09ｨｰ02ｨｬｨｪ04ｨｬ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺ06ｨｬ ｨｰ0208ｨ ｨｨｨｪｨ 00ｨｨｨｪ06ｨｬ ｨｰｨ ｨｪ01ｨ 08ｨｰｨｪ06ｨｦ ｨｬ02 (250ｨｬ ｨ 08ｨ ｨｰｨ, 0601ｨｨｨｪ 08ｨ ｨｮｨｰｨｺｨｨ, 09 ｨｰ02 ﾂ02ｨｪｨｨ02 ｨｰ ｨｬ ), ｨｮ0707ｨ (15 ﾂ ｨｺ) ｨｮ ﾂｨ 05ｨｨ ｨｰ0208ｨ ｨｨｨｪｨ 00ｨｨｨｪ ﾂ02ｨｰｨ ｨｪｨｨｨｨ 09 ｨｨｨｬｨｬｨｮｨｪｨｪ06ｨｬ0601ｨｮ0507ｨｰ060806ｨｬ ｨｨ06ｨｺ09ｨｨ0106ｨｪｨｨ02ｨｬ ｨｬ00 09ｨｪｨｮｨｰ08ｨｨｨｬ ﾂｨｪ06, ﾂ ｨｪｨｹ, ｨｪｨ ｨｺｨｮ ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｦ, ｨｮ0707ｨ (15 ﾂ ｨｺ) ｨｮ ﾂｨ 05ｨｨ ｨｰ0208ｨ ｨｨｨｪｨ 00ｨｨｨｪ ﾂ02ｨｰｨ ｨｪｨｨｨｨ 09 ｨｪｨ ｨｪ020902ｨｪｨｨ02ｨｬ ｨｪｨ ｨｪ0600ｨｰ ｨ 09ｨｰｨｨｨｪｨｺｨｨ 8% 05ｨ ｨｺｨ 09ｨ ｨｰ08ｨ 0002ｨｪ (1-ｨｦ ｨｬ ｨｪ0209ｨｪ06, 2-ｨｦ ｪ 2 08ｨ 04ｨ 09 ｨｪ , ｨｬ ｨ ｪ 1 08ｨ ｨｪ ). 07 ｨ 0605ｨｹｨｪ ｨｦ 0008ｨｮ ｨｨ ｨｺ06ｨｪｨｰ080605ｨｹｨｪ06ｨｬ ｨｨ ｨ ｨｪｨｨｨｨ ﾂ ｨｬ ｨ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨ 07 ｨｨ ｨｬｨｨｨｺ ｨｨ ﾂ0209ｨｺｨ 07 ｨｨ ﾂ02ｨｪｨｪ0609ｨｰｨｹ ｨ 0405ｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪｨ ｨｮ 78 (85%), ｨｬｨｨｨｺ ｨｨ ﾂ0209ｨｺｨ 07 ｨｮ 3-01, ｨｺｨｰｨ ｨｪ02 ｨｪｨ ｨ ｨ ｨｹ ｨｮ 8-ｨｬｨｨ 07ｨ 02ｨｨ02ｨｪｨｰ ｨｰ060806ｨｦ 0008ｨｮ (15 ﾂ ｨｺ) ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨ 07 ｨｨ ｨｬｨｨｨｺ ｨｨ ﾂ0209ｨｺｨ 07 ｨｨ ﾂ02ｨｪ-

12 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ ｨｪ0609ｨｰｨｹ ｨｮ09ｨｰｨ ｨｪ ｨｪｨ ｨｮ ﾂｨ 0701 (95%), 0502 ﾂ02ｨｪｨｨ02 ｨｪ ｨｨｨｪ ｨｮ05ｨｹｨｰｨ ｨｰ0609 ｨｮ 0601ｨｪ ｨ 0605ｨｹｨｪ ｨｰ0802ｨｰ02ｨｦ 0008ｨｮ ｨｮ ｨ 0605ｨｹｨｪ ｨｰｨｬ02 ﾂｨ ｨｹ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺ0602 ｨｨ ｨｬｨｨｨｺ ｨｨ ﾂ0209ｨｺ0602 ｨｨ ﾂ02ｨｪｨｨ02. 01ｨ 0006ｨｪ ｨｪｨｪ06ｨｦ 09ｨ ｨｪｨ 02ｨｨｨｨ ｨｨｨ ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｮ ｨｪｨ ｨ ｨ 02ｨｬ0401 ｨ 0605ｨｹｨｪ ｨｨ06ｨ ｨ ｨ 0608ｨｰｨｨ09ｨｪ04ｨｦ 01ｨ 08ｨ ｨｺｨｰ ｨｪｨｨ04ｨｨ050609ｨｹ ﾂｨｨ ｨｨ01ｨｨ (09 1,5 08ｨ 04ｨ ), ｨｮ0105ｨｨｨｪｨｨ ｨｬ ｨｨ01ｨｨ09ｨｪ04ｨｦ ｨｨ0601 ( ｨ ), ｨｮｨｬ02ｨｪｨｹ03ｨｨ05ｨ 09ｨｹ ｨｴｨ 01ｨｹ ｨｨ 0609ｨｰ0806ｨｰｨ ｨｨｨ ｨｰｨｨ ﾂ0209ｨｺ ｨ (ｨｨｨｪ0102ｨｺ09 PASI 09ｨｪｨｨ04ｨｨ ,5-2 08ｨ 04ｨ ), ｨｮ06ｨｴｨｨ02 06ｨ 0609ｨｰ0802ｨｪｨｨ ｨｺｨｮ07ｨｨ080609ｨ 05ｨｨ09ｨｹ. 0308ｨｨ ﾂ02ｨｬ ｨｰ0208ｨ ｨｰｨｨ ﾂ0209ｨｺｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｨｨ ｨｰｨｨ ﾂ0209ｨｺ ｨ ｨ 0405ｨ ｨ ｨ 0302ｨｪｨ ｨｮ ｨ 0605ｨｹｨｪ ｨｰ060806ｨｦ 0008ｨｮ070704, ｨｺ0806ｨｬ02 ｨｰ060006, ｨｮ ｨｪｨｨ01 ｨｰｨ ｨｺ ｨｰｨｬ02 ﾂｨ 05ｨ 09ｨｹ ｨｪ0608ｨｬｨ 05ｨｨ04ｨ 02ｨｨ07 ｨｨｨｬｨｬｨｮｨｪｨｪ ｨｨ ﾂ0209ｨｺｨｨ ｨｺｨ 04ｨ ｨｰ020502ｨｦ. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, ｨｮ ｨ 0605ｨｹｨｪ ｨｨｨ 0406ｨｬ 0708ｨｨ ｨｪｨ 05ｨｨ ﾂｨｨｨｨ 06ｨｪｨｨ0106ｨｬｨｨｨｺ0604ｨ, 04ｨ ｨ ｨ ｨｪｨｨ ｨｰ02ｨｺｨ 02ｨｰ ｨｰ ｨｨ 01ｨｮ ｨ 02ｨｰ ｨｰｨ ｨｪ01ｨ 08ｨｰｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ. 00 ｨｰ ｨｬ ｨｨ 09ｨ ｨｪｨ 02ｨｨｨｨ ｨｬｨｨｨｺ06ｨｰｨｨ ﾂ0209ｨｺ06ｨｦ ｨｨｨｪ0002ｨｺ02ｨｨｨｨ, 09ｨｨ09ｨｰ02ｨｬｨｪ04ｨｬｨｨ ｨ ｨｪｨｰｨｨｨｬｨｨｨｺ06ｨｰｨｨｨｺｨ ｨｬｨｨ ｨｪｨ ｨ ｨ 02ｨｰ ｨｨｨｦ ｨｰ0208ｨ ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｺｨｰ ｨｺｨ ｨｺ 09 06ｨｰｨｪ060302ｨｪｨｨｨｨ ｨｬｨｨｨｺ06ｨｰｨｨ ﾂ0209ｨｺ060006, ｨｰｨ ｨｺ ｨｨ ｨｨｨ ｨｰｨｨ ﾂ0209ｨｺ ｨ. 03ｨｴ02 ｨ ｨ 0302ｨｪｨｪ04ｨｬ 0502 ﾂ02ｨ ｨｪ04ｨｦ ｨｮ05ｨｹｨｰｨ ｨｰ 09ｨｰｨ ｨｪ0609ｨｨｨｰｨｹ ｨｨ 0601ｨｪ ｨｬ02ｨｪｨｪ06ｨｬ ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨｨｨｨ ｨｨｨｬｨｬｨｮｨｪ06ｨｬ0601ｨｮ0507ｨｰ0608ｨ ｨｨ06ｨｺ09ｨｨ0106ｨｪｨｨｨｦ ｨｨ05ｨｨ ｨｬ0209ｨｰｨｪ06ｨｬ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨｨｨ 05ｨ ｨｺｨ 09ｨ ｨｰ08ｨ 0002ｨｪ. 02ｨ ｨｪｨｪ ｨｬ ﾂ02ｨｪｨｨ07 ｨｬ0603ｨｪ ｨｺ06ｨｬ02ｨｪ010609ｨ ｨｰｨｹ ｨ ｨｨ0806ｨｺ ｨｨｨｬ02ｨｪ02ｨｪｨｨ ｨｨ 06ｨｪｨｨ0106ｨｬｨｨｨｺ ｨｮ ｨ 0605ｨｹｨｪ ｨｨｨ 0406ｨｬ ﾁ , ｨ ｨｰ040803ｨｨｨｪｨ ｨ ｨ ｨｬｨ ｨｰ060902ｨｪ ｨｨｨｨ 08ｨ 04ｨ ｨｪ09ｨｺ06ｨｦ ｨ 04ｨ ｨｪｨｹ ｨｪｨｨｨｰｨ 05ｨｹｨｪ04ｨｦ ｨｺｨ ｨｪ01ｨｨ (070108) ｨｰ ｨｨ0806ｨｺ06 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｪ04ｨｬ 04ｨ ｨ ｨ ｨｪｨｨ02ｨｬ, ｨｺ06ｨｰ ｨｪｨｨ ｨ 08ｨ ｨｺｨｰ0208ｨｪ ｨｪｨｨ ﾂ0209ｨｺ ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴ0202 ｨｰ02 ﾂ02ｨｪｨｨ02 ｨｨ ｨｪｨｨ02 ｨｮ09ｨｰ06ｨｦ ﾂｨｨ090609ｨｰｨｨ ｨｺ ｨｰ0208ｨ 07ｨｨｨｨ ｨｺ ｨｹ ｨｮ 0302ｨｪｨｴｨｨｨｪ 0102ｨｰ ｨｪ ｨ 09ｨｰｨ, 09ｨｰ08ｨ 01ｨ 06ｨｴｨｨ ｨｪｨｨ- ﾂ0209ｨｺｨｨｨｬｨｨ ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ ｨ ｨｪｨｨ07ｨｬｨｨ ｨ ｨｪ0609 ｨｬｨ ｨｰｨ 04ｨ ( ), ｨｨ0008ｨ 02ｨｰ ｨｪｨｪｨｮ ｨｹ ｨｬｨｨ080609ｨ ｨｪｨｨｨｨ ｨｮｨｺｨｰｨｨ09ｨｪ ｨｰ0208ｨｹ ﾂ02ｨｰｨ ｨｪｨｨｨｨ ｨｮ00ｨｨｨｬｨｨ ｨｨｨｪ0002ｨｺ02ｨｨ07ｨｬｨｨ, ｨ 09ｨ 02ｨｬ04ｨｬｨｨ ｨｬ 07ｨｮｨｰ02ｨｬ ｨｨ05ｨｨ ｨｨ0102ｨｪｨｰｨｪ06ｨｦ ｨｦ, ｨｪ ｨｪｨ ｨｬｨｨ ｨｮ 26,0% (626) ｨｨ ｨ ｨ ｨｪｨｪ ｨ 02ｨｨ02ｨｪｨｰ06ｨｺ, 09ｨｰ08ｨ 01ｨ 06ｨｴｨｨ , ｨｮ ﾂｨ 09ｨｰｨｨ ｨｺ06ｨｰ ｨｨｨｬ0205ｨｨ09ｨｹ ｨ 0502ｨｬ ｨｮｨｺｨｰｨｨ09ｨｪ ｨｹ ｨｰ08ｨｮｨｺｨｰｨｮ ｨｪｨ ｨｪ02-albicans ｨｮ ｨｪｨｨｨｰｨ 05ｨｹｨｪ04ｨｦ ｨｺｨ ｨｪ01ｨｨ010604, 06ｨ ｨｮ ｨｪｨｪ04ｨｦ C. tropicalis, C. krusei, C. kefyr ｨｨ C. glabrata 0708ｨｨ010601ｨｨ050609ｨｹ 14,2% (89), 0708ｨｨ ﾂ02ｨｬ 09 55,1% 06ｨｪ ｨｨ09ｨｰ08ｨｨ080609ｨ ｨｺｨ ｨｺ ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴｨｨｨｦ. 0805ｨｨｨｪｨｨ ﾂ0209ｨｺｨ ｨ ｨｺｨｰｨｨｨｺｨ 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ02ｨｰ 06 ｨｰ06ｨｬ, ﾂｨｰ06 ｨｨｨｬ02ｨｪｨｪ06 ｨｮ 01ｨ ｨｪｨｪ ｨ 02ｨｨ02ｨｪｨｰ06ｨｺ ﾂｨ ｨｴ ｨｨ09ｨｰ08ｨｨ08ｨｮ06ｨｰ ｨｮ ﾂｨ ｨｨ ｨｰ0608ｨｪ ｨｨｨｪ00ｨｨ02ｨｨ080609ｨ ｨｪｨｨ07 ｨｨ05ｨｨ ｨｨ01ｨｨ ｨ ｨｪｨｨ ｨｬ02 ｨｰ060006, ｨｮ ｨｪｨｨ01 ｨｪ ｨｺ06 ｨｪｨ ｨ ｨ 06ｨｰ0907 ｨｪｨ 08ｨｮ0302ｨｪｨｨ ｨｨ09ｨｰ02ｨｬ02 ｨｬｨｪ060006ｨｮ080609ｨｪ ｨ ｨｪｨｰｨｨ00ｨｮｨｪ00ｨ 05ｨｹｨｪ ｨ ｨ 08ｨｹ0208ｨ, ｨｺ0605ｨｨ ﾂ0209ｨｰ0902ｨｪｨｪ0402 ｨｨ ｨｺｨ ﾂ0209ｨｰ0902ｨｪｨｪ0402 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ ｨｨ 06-ｨｺ0502ｨｰ06 ﾂｨｪ06ｨｦ 09ｨｨ09ｨｰ02ｨｬｨ 01 ｨｨｨｬｨｬｨｮｨｪｨｨｨｰ02ｨｰｨ, 06ｨｰｨｺ0506ｨｪ02ｨｪｨｨ07

13 130606ｨｬ II. 0105ｨ 09ｨ 1 13 ｨｮ080609ｨｪ02ｨｦ ｨｬ06ｨｪ ｨｰ 01ｨｨｨ 07ｨ 0406ｨｪｨ ｨｪ0608ｨｬ04, ﾂｨｰ06 06ｨ ｨｮ ｨｨ09ｨ 02ｨｰ ｨｬ0603ｨｪ0609ｨｰｨｹ ｨ ｨｨｨｨ 09 09ｨｨ0102 ｨ ｨｨｨｨ ｨｨ 08ｨ 0409ｨｨｨｰｨｨ07 ｨｰｨｺｨ ｨｪ ｨ ｨｺ02ｨｨｨｦ, 0708ｨｨｨｪ02ｨｨ07ｨｨｨ 05ｨｹｨｪ06 06ｨｰ05ｨｨ ﾂｨ 06ｨｴｨｨ ｨｰ0607ｨｪｨｨ07 ｨｺｨ ｨｪ01ｨｨ0106ｨｪ0609ｨｨｨｰ0205ｨｹ09ｨｰ09ｨ ｨｨ ｨｺｨ ｨｪ01ｨｨ010607ｨ ｨｰｨｨｨｨ 06ｨｰ ｨｺｨ ｨｪ01ｨｨ010604ｨ ｨｨ ｨｴｨｨ ｨｨ ﾂｨｨｨｪ06ｨｦ 0105ｨｨｨｰ0205ｨｹｨｪ ｨｨ09ｨｮｨｰ09ｨｰ09ｨｨ ｨ ｨｮ01ｨｨｨｰ020502ｨｦ ｨ ｨｪｨｨ04ｨｬ ｨｹ040609ｨ ｨｪｨｨ02 ｨｪｨ ｨｮ 09 ｨ ｨｨ09ｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨ02ｨｦ (09ｨｨ09ｨｰ02ｨｬｨｪ ｨｰｨｨ0906ｨｺｨ ｨｪ01ｨｨ010604ｨｪ ｨ 08ｨ ｨｰ04) ｨｨ05ｨｨ 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨｬ06ｨｪ06ｨｰ0208ｨ 07ｨｨｨｨ ｨｪｨｨ07 ｨｨｨｪｨ ｨｺｨｰｨｨ09ｨｨ080609ｨ ｨｪｨｪ ｨ ｨｺｨｰ06ｨ ｨ ｨｺｨｰ0208ｨｨｨｦ (09ｨ ｨｺ02ｨｨｨｪｨ ｨｺ06ｨｰ08ｨｨ010609ｨ ｨｺ) ｨｰ, 0706 ｨｪｨ 03ｨｨｨｬ 01ｨ ｨｪｨｪ04ｨｬ, 09 98,6% ｨｨ 81,3% 0905ｨｮ ﾂｨ ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06 ｨｮ09ｨｰ08ｨ ｨｪｨｨｨｰｨｹ ｨｬｨｨｨｺ06ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰ ｨ 0502ｨｪｨｨ ｨｰｨ ｨｪ ｨｪｨｨ ｨｨｨｰ0205ｨｹｨｪ ｨｺｨｰｨ, ｨｪｨｨ07 06ｨｰ ｨｰ ﾂ02ｨｰ ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｦ ,5 ｨｬ ｨｺ06ｨｰ08ｨｨ010609ｨ ｨｺｨ, ｨｰ 09 ﾂｨｨｨｰｨ ｨｰｨｹ 01ｨ ｨｪｨｪ04ｨｦ ｨ 08ｨ ｨｰ ｨｦ ｨ 05ｨｹｨｰ0208ｨｪｨ ｨｰｨｨ0906ｨｦ 0708ｨｨ 0904ｨ ｨｬ02ｨｰ0601ｨ ｨｰ0208ｨ 07ｨｨｨｨ 0302ｨｪｨｴｨｨｨｪ 0102ｨｰ ｨｪ ｨ 09ｨｰｨ, 09ｨｰ08ｨ 01ｨ 06ｨｴｨｨ ｨｨ ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴｨｨｨｬ ｨｮ ｨｪｨｨｨｰｨ 05ｨｹｨｪ04ｨｬ ｨｺｨ ｨｪ01ｨｨ ｨｬ ﾁ ｨｮ , 00ｨ 03ｨ ｨｨｨｪ , ﾁｨｨ09ｨｰ07ｨｺ0609ｨ , 08ｨ ｨｮｨｺ ｨｪｨｰ08ｨ 05ｨｹｨｪ04ｨｦ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｺ0603ｨｪ ｨｪ ｨｨ ﾂ0209ｨｺｨｨｨｦ 01ｨｨ0907ｨ ｨｪ ｨｺ09ｨ 04ｨ 04ｨｪ ｨｰｨｪ04ｨｦ 05ｨｨ03ｨ ｨｦ ｨｰ ｨｪｨｨｨｬ ｨｨ04 ｨｪｨ ｨｨｨ ﾂｨ 09ｨｰ ｨｰ0802 ﾂｨ 06ｨｴｨｨ ｨ ｨ ｨ ｨｪｨｨｨｦ ｨ ｨｺｨｰｨｨｨｺ ｨ ﾂｨ ｨｬｨ ｨｰ ｨｪ ｨ. 05ｨ ｨｪ ｨｬ07 ｨｪｨ ｨ ｨ 02ｨｰ ｨｰ 04ｨ ｨ ｨ 02ｨｬ0609ｨｰｨｨ ｨｨ 09 ﾂｨ 09ｨｰ04ｨｬ, ｨｦ ｨｪ0206ｨ 0609ｨｪ0609ｨ ｨｪｨｪ04ｨｬ 0708ｨｨ02ｨｬ06ｨｬ ｨ ｨｪｨｰｨｨｨ ｨｨ06ｨｰｨｨｨｺ0609, ｨｮ01ｨｮ ｨｪｨｨ02ｨｬ 05ｨｺ ｨｨ ﾂ0209ｨｺ06ｨｦ 06ｨ 09ｨｰｨ ｨｪ0609ｨｺｨｨ, 0708ｨｨ02ｨｬ06ｨｬ ｨ 08ｨ ｨｰ0609,09ｨｪｨｨ03ｨ 06ｨｨ01 ｨｨｨｬｨｬｨｮｨｪｨｨｨｰ02ｨｰ, 08ｨ ｨｰ08ｨ ｨｪ02ｨｪｨｨｨｨ ｨｪｨ 08ｨｺ06ｨｬｨ ｨｪｨｨｨｨ ｨｨ ｨｰ06ｨｺ09ｨｨｨｺ06-ｨｬｨ ｨｪｨｨｨｨ, 0006 ﾁ-ｨｨｨｪ0002ｨｺ02ｨｨｨｨ ｨｨ 0108ｨｮ00ｨｨｨｬｨｨ 0708ｨｨ ﾂｨｨｨｪｨ ｨｬｨｨ ｨ ｨｮ01ｨｨｨｰ0205ｨｹ 08ｨ 04ｨｪ ｨｰｨｪ (06ｨｰ08ｨｮｨ 0209ｨｨ01ｨｪ060006) 05ｨｨ03ｨ ｨｨ09ｨ 05 Robin ｨｮ ｨｨ 01ｨ 05 02ｨｬｨｮ ｨｪｨ 0409ｨ ｨｪｨｨ02 Malassezia furfur (furfur ｪ 06ｨｰ08ｨｮｨ ｨｨ) ｨｮ ｨ 0405ｨｨ 0607ｨｨ09ｨ ｨｪ ｨｨ ﾂ0209ｨｺｨｨ02 ｨｨ 0609ｨ 05ｨｹｨｪ ｨｬ ｨｨｨ ｨ. 00 ｨｪｨ 09ｨｰ0607ｨｴ ｨｬ07 09 ﾂｨｨｨｰｨ 02ｨｰ0907, ﾂｨｰ06 06ｨ 02 08ｨ 04ｨｪ0609ｨｨ01ｨｪ0609ｨｰｨｨ ｨｰ ｨ 0405ｨｨ ﾂｨｪ04ｨｬｨｨ 09ｨｰｨ 01ｨｨ07ｨｬｨｨ 09 03ｨｨ04ｨｪ02ｨｪｨｪ06ｨｬ 02ｨｨｨｺ ｨｨｨ ｨ. 06ｨｪｨｰ02ｨｪ09ｨｨ09ｨｪ0609ｨｰｨｹ 04ｨ ｨｪｨｨ07 ｨｺ0603ｨｨ P orbiculare (ovale) 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ 00ｨｮｨｪｨｺ02ｨｨ06ｨｪｨ 05ｨｹｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 09ｨ 05ｨｹｨｪ , ﾂｨｰ ｨ ｨｪ ｨｨ070600ｨｨ05ｨｹｨｪ04ｨｬｨｨ ｨｦ09ｨｰ09ｨ ｨｬｨｨ. ｨ ｨｴ ｨ ｨ ｨ ｨｪｨｨ02 08ｨ 0409ｨｨ09ｨ 02ｨｰ ｨ 09ｨｰ ｨｰ ｨｰｨｪ060302ｨｪｨｨ02 ｨｬ020301ｨｮ 0302ｨｪｨｴｨｨｨｪｨ ｨｬｨｨ ｨｨ ｨｬｨｮ03 ﾂｨｨｨｪｨ ｨｬｨｨ ｨｰｨ ｨｰ 2: ｨ ｨ 00ｨ 06ｨｴｨｨｨｬｨｨ 00ｨ ｨｺｨｰ0608ｨ ｨｬｨｨ ｨｰ0907: ｨｪｨｨ ｨ ｨｨ, ｨｪｨｪｨ ｨｰ05ｨｨ090609ｨｰｨｹ ｨｨ ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ02 01ｨｨｨｬｨｨ ﾂ0209ｨｺ ｨｰｨ 09ｨ 0706ｨｰｨ, ｨ 0409ｨ ｨｪｨｨ ｨ 08ｨｺ06ｨｬ ｨｺ05ｨｨｨｬｨ ｨｰ02, 07ｨ ｨｰ ｨｨ07 09ｨｪｨｮｨｰ0802ｨｪｨｪｨｨ ｨ ｨｪ0609 ｨ ｨｰｨ ｨｺ ｨｪ02ｨｰｨｨ ﾂ0209ｨｺｨ ｨ ｨｪｨｪ0609ｨｰｨｹ ｨｪｨｨｨｺｨｪ060902ｨｪｨｨ0604ｨ ｨ ｨ ｨｪｨｨ ｨ 09ｨｰ09ｨｮ02ｨｰ ｨ ｨｪｨｰｨｨｨ ｨ ｨｺｨｰ0208ｨｨｨ 05ｨｹｨｪｨ 07 ｨｨ05ｨｨ ｨｺ0608ｨｰｨｨｨｺ0609ｨｰ020806ｨｨ01-ｨｪｨ 07 ｨｰ0208ｨ 07ｨｨ07, 05ｨｪ0106ｨｺ08ｨｨｨｪｨｪｨ 07 07ｨ ｨｰ ｨｨ07, ｨｪｨｨ ﾂ0209ｨｺｨｨ02 04ｨ ｨ ｨ ｨｪｨｨ ｨｮ0106 ﾂｨｪ06-ｨｺｨｨ0302 ﾂｨｪ ｨｰ08ｨ ｨｺｨｰｨ ｨ ｨｰｨ ｨｺ ｨｰ0607ｨｪｨｨ ｨｨ ﾂｨｪ060006ｨｨ 09ｨｰ0608ｨｨ ﾂｨｪ ｨｨｨｬｨｬｨｮｨｪ ｨｨ02ｨｨｨｰｨ ｨ ｨｨｨｬ06 06ｨｰｨｬ02ｨｰｨｨｨｰｨｹ ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ0709 ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺ06ｨｦ 09ｨｨｨｬ07ｨｰ06ｨｬｨ ｨｰｨｨｨｺ02,

14 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ ｨｬｨｨｨｺ ｨｨｨｨ ｨｨ ｨｨ02 04ｨ ｨｪ ｨｬ07 ( ｨｪｨｨ02 09ｨｰ0208ｨｰ ｨｬ, ｨ ｨｰｨｨ07ｨｨ ﾂｨｪ06ｨｦ 0506ｨｺｨ 05ｨｨ04ｨ 02ｨｨｨｨ ｨ ｨｪｨｨｨｦ ( ｨｨ 09 ｨ ｨｺｨｰｨｮｨ 05ｨｹｨｪ0609ｨｰｨｹ ｨ 0502ｨｬ04 08ｨ 0408ｨ ｨ 06ｨｰｨｺｨｨ 08ｨ 0405ｨｨ ﾂｨｪ0401ｨｬ02ｨｰ ﾂ02ｨｪｨｨ07 08ｨ 04ｨｪ ｨｰｨｪ ｨｨ03ｨ 07 ｨｪｨ ｨｬｨｨ ｨ 0405ｨ ｨｪｨ 08ｨ ｨ 06ｨｰｨ 0706 ｨｨ ｨ ｨｪｨｨ ｨ 09ｨｪｨｨｨｰ0205ｨｹｨｪ06ｨｦ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ ｨｬ0209ｨｰｨｪ ﾂ02ｨｪｨｨ07 2% ｨｺ0802ｨｬ06ｨｬ 0001ｨｨ040608ｨ 0503 (070806ｨｨ ｨｨｨｰ0205ｨｹ- ｨｺ06ｨｬ07ｨ ｨｪｨｨ07 08ｨｪ090902ｨｪ-09ｨｨ05ｨ 00 (09 ｨｺｨ ﾂ0209ｨｰ0902 ｨｬ06ｨｪ06ｨｰ0208ｨ 07ｨｨｨｨ ｨｨ ｨｺ06ｨｬｨ ｨｨｨｪｨｨ080609ｨ ｨｪｨｪ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ (ｨｪｨ 08ｨｮ03ｨｪｨ 07 ｨｰ0208ｨ 07ｨｨ07 ｨｺ0802ｨｬ06ｨｬ 0001ｨｨ040608ｨ ﾂ02ｨｰｨ ｨｪｨｨｨｨ ｨｨ02ｨｬ06ｨｬ ｨｪｨｨ040608ｨ 05ｨ 09 09ｨｨ0102 ｨｰｨ ｨ 0502ｨｰ06ｨｺ 09 09ｨｮｨｰ06 ﾂｨｪ06ｨｦ ｨｬ00 09 ｨｰ02 ﾂ02ｨｪｨｨ ｨｪ02ｨｦ ﾂ02ｨｪ06 22 ｨ 0605ｨｹｨｪ0401, ｨｨ ｨｺ06ｨｰ ｨｪｨｴｨｨｨｪ ｨｨ 7 ｨｬｨｮ03 ﾂｨｨｨｪ ｨ 09ｨｰ02 06ｨｰ ｨｰ. 0205ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ 04ｨ ｨ ｨ ｨｪｨｨ ｨｰｨ 09ｨｨ05ｨ 06ｨｰ 4 ｨｬ ｨｰ, 0706 ﾂｨｰｨｨ ｨｮ ｨ 0605ｨｹｨｪ ｨｬｨ ｨｰ0604 ｨｨｨｬ ｨｪｨｨ ﾂ0209ｨｺｨｨｨｦ, ｨｨ01ｨｨ09ｨｨ08ｨｮ06ｨｴｨｨｨｦ 01ｨ 08ｨ ｨｺｨｰ ｨｨ 06ｨ ｨ ｨｪｨｨｨｨ ｨｮｨｰ09ｨｰ09ｨｮ06ｨｴｨ 07 05ｨｪ0106ｨｺ08ｨｨｨｪｨｪｨ 07 07ｨ ｨｰ ｨｨ ｨｪｨ ｨｮ 9 07ｨ 02ｨｨ02ｨｪｨｰ0609, ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 09 ｨｨｨｬｨｬｨｮｨｪ060008ｨ ｨｬｨｬ02 (ｨｮｨｬ02ｨｪｨｹ0302ｨｪｨｨ ｨｨｨｬ000602ｨｨｨｰ0609 ｨｨ ｨｪｨｨ02 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 00-05ｨｨｨｬ000602ｨｨｨｰ0609) ｨｮ 19 ｨ 0605ｨｹｨｪ ｨｨｨ 00ｨｪ0604 ｨ ｨｰｨ ｨｪ ｨｪｨ 0609ｨｪ0609ｨ ｨｪｨｨｨｨ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨｨ ｨｪｨｨｨｦ, ｨｰ ｨｪ ｨｬｨｨｨｺ080609ｨｺ0607ｨｨ ﾂ0209ｨｺｨｨ, ｨ 06ｨｦ 09ｨ 05ｨｹ040208ｨ ｨ ｨｰｨ ｨｺ ｨ 08ｨ ｨｺｨｰ0208ｨｪ04ｨｬ ﾂ02ｨｪｨｨ02ｨｬ09 05ｨｮ ﾂｨ 01 05ｨ ｨｬ ｨｮ01ｨ ｨｺ ｨｪｨ ｨ ｨｪｨｨ ｨｰｨ 09ｨｨ05 11 ｨｬ ｨｨｨｺ ｨｨ ﾂ0209ｨｺ0602 ｨｨ ﾂ02ｨｪｨｨ02 ｨｪｨ 09ｨｰｨｮ07ｨｨ0506 ｨ 0409ｨｰ ( ｨｪ02ｨｬ ｨｪｨ 15 01ｨｪ02ｨｦ (ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609, ｨｮ ﾂｨ 0903ｨｨ01 ｨｺ06ｨｬｨ ｨｨｨｪｨｨ080609ｨ ｨｪｨｪ ﾂ02ｨｪｨｨ ｨｬ02 ｨｰ060006, ｨｨ01ｨｨ ｨ ｨ ｨ ｨｪｨｨ07 ﾂｨ ｨｴ ｨｰ0802 ﾂｨ 05ｨｨ09ｨｹ ｨｮ ｨ 0605ｨｹｨｪ0401,070605ｨｮ ﾂｨ 0903ｨｨ01 ｨｰ0605ｨｹｨｺ06 ｨｪｨ 08ｨｮ03ｨｪ ﾂ02ｨｪｨｨ02 (ｨｮ 0601ｨｪ ｨ 02ｨｨ02ｨｪｨｰｨ,070605ｨｮ ﾂｨ ｨｨ09ｨｰ02ｨｬｨｪｨｮ06 ｨｰ0208ｨ 07ｨｨ06 ｨｨ ｨｮ 8 07ｨ 02ｨｨ02ｨｪｨｰ0609, ｨｮ ﾂｨ 0903ｨｨ01ｨｰ0605ｨｹｨｺ06 ｨｪｨ 08ｨｮ03ｨｪ ﾂ02ｨｪｨｨ02) 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ ｨｪｨ ｨｬｨｨ ｨ ｨｪ ｨｪ0206ｨ ｨｨｨｬ0609ｨｰｨｨ ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨｨ07ｨｺ06ｨｬ070502ｨｺ09ｨｪ ｨｨ09ｨｰ02ｨｬｨｪ ｨｰｨｨ06ｨｰ080607ｨｪ ﾂ02ｨｪｨｨ07 08ｨ 04ｨｪ ｨｰｨｪ ｨｨ03ｨ ｨｨ 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨｨｨ ｨｰ0902ｨｰ09ｨｰ09ｨｮ06ｨｴｨｨ ｨｰｨｨ ｨｺｨ 04ｨ ｨｪｨｨｨｦ ｨｮ , ﾂ02ｨｪｨｺ , ﾁｨｮ05ｨｺ0609ｨ , 01ｨ ｨｰ080609ｨ ｨｨｨｪｨｨｨｺ ｨｨ ﾂ0209ｨｺｨ 07 05ｨ ｨ 0608ｨ ｨｰ08ｨｨ07 ｨｺ0603ｨｪ ｨｪ ｨｨ ﾂ0209ｨｺ ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺ ｨｨ0907ｨ ｨｪ090208ｨ ｨｬｨｨｨｰ02ｨｰｨ ｨ ｨ ｨｪ02ｨｪｨｨ ｨｺ ｨｺ09ｨ 0108ｨｨｨ ｨ Candida 03ｨｨ0806ｨｺ06 08ｨ ｨｰ08ｨ ｨｪ02ｨｪ ｨｨ , 09ｨ ｨｨｨｰｨｨ08ｨｮ06ｨｰ ｨｪｨ ｨｺ ｨｨ 0905ｨｨ04ｨｨ09ｨｰ ｨ ﾂｨｺｨ ｨｰ ｨｰｨｺｨｨ, ｨｪ0609ｨ, 07ｨｨｨｴ0209ｨ 08ｨｨｨｰ0205ｨｹｨｪ060006, ｨｬ06 ﾂ ｨｰ08ｨ ｨｺｨｰ0609 ﾂ ｨｺｨ, ｨｹ ｨ ｨｨｨ ｨｪｨｰ06ｨｬ ｨｪ0608ｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｬｨｨｨｺ ｨｨ 0708ｨｨ ｨｪｨｪ0401 ｨｮ ｨｨ0701 ｨｬ0600ｨｮｨｰ 0708ｨｨ06ｨ 0802ｨｰｨ ｨｰｨｹ 07ｨ ｨｰ060002ｨｪｨｪ ｨｦ09ｨｰ09ｨ. 00 ｨｪｨ 0302ｨｦ 05ｨ ｨ 0608ｨ ｨｰ0608ｨｨｨｨ ｨｨｨｰ ｨｨｨ 00ｨｪ0609ｨｰｨｨｨｺｨ , 09 ｨｰ06ｨｬ ﾂｨｨ ｨｪｨｨｨｰｨ 05ｨｹｨｪ ｨｺｨ ｨｪ01ｨｨ010604ｨ. 00ｨ ｨｰ0208ｨｨｨ 0506ｨｬ ｨｨ ｨ ｨｪｨｨ ｨｮ03ｨ ｨｰ ｨｺ06ｨ ｨｨ04ｨｨ09ｨｰ06ｨｦ 0905ｨ 00ｨ 05ｨｨｨｴｨ, 09ｨｮ05ｨｹ0904, ｨｮ0802ｨｰ0804, 06ｨｺ08ｨｮ03ｨ 06ｨｴ02ｨｦ ｨｺ0603ｨｨ ｨｨ ｨ ｨｪｨｨ ｨｬｨｨｨｺ080609ｨｺ060706ｨｬ ｨｬｨ ｨｰ0208ｨｨｨ 05 06ｨｺ08ｨ 03ｨｨ09ｨ 02ｨｰ ｨ ｨｬｨｮ ｨｨ05ｨｨ ｨｬ02ｨｰｨｨ0502ｨｪ060904ｨｬ 09ｨｨｨｪｨｨｨｬ. 0308ｨｨ ｨｨ04ｨｮ ﾂ02ｨｪｨｨｨｨ ｨｬｨ 04ｨｺ ｨｰｨｬ02 ﾂｨ 06ｨｰ ｨｪｨ 05ｨｨ ﾂｨｨ ｨｺ0502ｨｰ06ｨｺ ｨｨ05ｨｨ ｨｬｨｨ020205ｨｨ07, 06ｨ 08ｨ ｨｴｨ 06ｨｰ 09ｨｪｨｨｨｬｨ ｨｪｨｨ02 ｨｪｨ ｨｺ0605ｨｨ ﾂ0209ｨｰ ｨｦｨｺ0602ｨｨｨｰ0609, ｨｰｨ 09 ｨ ｨ ｨｺｨｰ0208ｨｨｨ 05ｨｹｨｪ06ｨｦ

15 130606ｨｬ II. 0105ｨ 09ｨ ｨｨ ｨｨ ｨ ｨｪｨｨｨｨ 7935 ｨｬｨ 04ｨｺ0609 (4711 ﾂ ｨｺ) ｨｮ 0008ｨｨｨ ｨ Candida ｨ 0405ｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ04 ｨｮ 211 ﾂ ｨｺ (4,5%), ﾂｨ ｨｴ02 ｨｮ 0302ｨｪｨｴｨｨｨｪ (92,2%). 02ｨ 04 ﾂｨｪ06 ｨｪｨ 05ｨｨ ﾂｨｨ ｨｺ0502ｨｰ06ｨｺ ｨｨ ｨｬｨｨ020205ｨｨ ｨ 08ｨ ｨｰ ｨ 02ｨｰ ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ04ｨｬ 0502ｨｦｨｺ0602ｨｨｨｰ060406ｨｬ ( ｨｦｨｺ0602ｨｨｨｰ ｨｪｨｨ07) ｪ 69,1%. 0201ｨｪｨ ｨｺ06 ｨｮ ﾂｨ 09ｨｰｨｨ 07ｨ 02ｨｨ02ｨｪｨｰ ｨｰｨ ｨｨｨｪ0002ｨｺ02ｨｨ07 ｨｪ ｨ 02ｨｰ ｨ 0302ｨｪｨｪ06ｨｦ ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨ02ｨｦ. 00ｨ ｨｰ0208ｨｨｨ 05, 09 ｨｺ06ｨｰ060806ｨｬ ｨｰ ｨｨ ｨｨ ｨｬｨｨ020205ｨｨｨｦ, ﾂｨ ｨｴ ｨｨｨｰ 09ｨｬ0203ｨ ｨｪｨｪｨｮ ｨｮ ｨ 05ｨ 01ｨ ｨｪｨｨ02ｨｬ 07ｨ 0506 ﾂ02ｨｺ ｨｦｨｪｨ (82,4%) ｨｨｨ 05ｨｹｨｪ06 ｨｪ02 06ｨｰ ｨｨ09ｨ 05ｨｨ 0906 ﾂ02ｨｰｨ ｨｪｨｨ02 Candida ｨｮ00ｨｨｨｬｨｨ ｨｨ 0505ｨｨｨｬｨｨｨｪｨ 02ｨｨ06 Candida ﾂ02ｨｪｨｨ ｨｰｨｨ ｨｨｨ ｨｺ060904ｨｬｨｨ ｨ 08ｨ ｨｰｨ ｨｨｨｬｨｨ. 0201ｨｪｨ ｨｺ06 ｨｮ 0006 ﾁ ｨｨｨｪ00ｨｨ02ｨｨ080609ｨ ｨｪｨｪ ｨ 02ｨｨ02ｨｪｨｰ0609 ( ) 06ｨｰｨｬ02 ﾂｨ 05ｨｨ 09ｨｰ06ｨｦｨｺ0602 ｨｪｨ 05ｨｨ ﾂｨｨ ﾂｨｺｨｮ06ｨｴｨｨ ｨｺ0502ｨｰ06ｨｺ ｨｨ ｨｬｨｨ020205ｨｨ07 09 ｨｨ ｨｮ02ｨｬ06ｨｬ ｨｬｨ ｨｰ0208ｨｨｨ ｨｰ02 ﾂ02ｨｪｨｨ02 3 ｪ 01 ｨｬ ﾂｨｪ06ｨｦ ｨｰｨｨ ｨｨｨ ｨｺ060906ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ ﾂ02ｨｪｨｺ , ｨｮ , ﾁｨｮ05ｨｺ0609ｨ , 01ｨ ｨｰ080609ｨ ｨｨｨｪｨｨｨｺ ｨｨ ﾂ0209ｨｺｨ 07 05ｨ ｨ 0608ｨ ｨｰ0608ｨｨ07 ｨｺ0603ｨｪ ｨｪ ｨｨ ﾂ0209ｨｺ ｨｨ0907ｨ ｨｪ090208ｨ ｨｬｨｨｨｰ02ｨｰｨ ｨ ｨ ｨｪ02ｨｪｨｨ ｨｺ ｨｺ09ｨ 0108ｨｨｨ ｨ Candida 03ｨｨ0806ｨｺ06 08ｨ ｨｰ08ｨ ｨｪ02ｨｪ ｨｨ , 06ｨｪｨｨ 04ｨ ｨｰ ｨｺ0603ｨｮ ｨｨ 0905ｨｨ04ｨｨ09ｨｰ ｨ ﾂｨｺｨｨ 0806ｨｰ ｨｰｨｺｨｨ, ｨｪ0609ｨ, 07ｨｨｨｴ0209ｨ 08ｨｨｨｰ0205ｨｹｨｪ ｨｰ08ｨ ｨｺｨｰｨ ﾂ ｨｺｨ. ﾁｨ 09ｨｰ06 09ｨ ｨｨｨｰｨｨ08ｨｮ06ｨｰ ｨｪｨ 0905ｨｨ04ｨｨ09ｨｰ ｨ ﾂｨｺｨ 01 ｨｬ06 ﾂ ｨｰ08ｨ ｨｺｨｰｨ ﾂ ｨｺｨ, ｨｹ ｨ ｨｨｨ ｨｪｨｰ06ｨｬ ｨｪ0608ｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｬｨｨｨｺ ｨｨ 0708ｨｨ ｨｪｨｪ0401 ｨｮ ｨｨ ｨｨ06ｨ 0802ｨｰｨ 06ｨｰ 07ｨ ｨｰ060002ｨｪｨｪ ｨｦ09ｨｰ09ｨ. 00 ｨｪｨ 0302ｨｦ 05ｨ ｨ 0608ｨ ｨｰ0608ｨｨｨｨ ｨｨｨｰ ｨｨｨ 00ｨｪ0609ｨｰｨｨｨｺｨ , 09 ｨｰ06ｨｬ ﾂｨｨ ｨｪｨｨｨｰｨ 05ｨｹｨｪ ｨ ｨｪ01ｨｨ010604ｨ. 00ｨ ｨｰ0208ｨｨｨ 0506ｨｬ ｨｨ ｨ ｨｪｨｨ ｨｮ03ｨ ｨｰ ｨｺ06ｨ ｨｨ04ｨｨ09ｨｰ06ｨｦ 0905ｨ 00ｨ 05ｨｨｨｴｨ, 09ｨｮ05ｨｹ0904, ｨｮ0802ｨｰ0804, 06ｨｺ08ｨｮ03ｨ 06ｨｴ02ｨｦ ｨｺ0603ｨｨ ｨｨ ｨ ｨｪｨｨ ｨｬｨｨｨｺ080609ｨｺ060706ｨｬ ｨｬｨ ｨｰ0208ｨｨｨ 05 06ｨｺ08ｨ 03ｨｨ09ｨ 02ｨｰ0907 ｨｬ02ｨｰｨｨ0502ｨｪ060904ｨｬ 09ｨｨｨｪｨｨｨｬ ｨｨ05ｨｨ ｨ ｨｬｨｮ. 0308ｨｨ ｨｨ04ｨｮ ﾂ02ｨｪｨｨｨｨ ｨｬｨ 04ｨｺ ｨｰｨｬ02 ﾂｨ 06ｨｰ ｨｪｨ 05ｨｨ ﾂｨｨ ｨｨ ｨｺ0502ｨｰ06ｨｺ ｨｨ05ｨｨ ｨｬｨｨ020205ｨｨ07, 06ｨ 08ｨ ｨｴｨ 06ｨｰ 09ｨｪｨｨｨｬｨ ｨｪｨｨ02 ｨｪｨ ｨｺ0605ｨｨ ﾂ0209ｨｰ ｨｦｨｺ0602ｨｨｨｰ0609, ｨｰｨ 09 ｨ ｨ ｨｺｨｰ0208ｨｨｨ 05ｨｹｨｪ06ｨｦ ｨｨ ｨｨ ｨ ｨｪｨｨｨｨ 7563 ｨｬｨ 04ｨｺ0609 (4117 ﾂ ｨｺ) ｨｮ 0008ｨｨｨ ｨ Candida ｨ 0405ｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ04 ｨｮ 168 ﾂ ｨｺ (4,1%), ﾂｨ ｨｴ02 ｨｮ 0302ｨｪｨｴｨｨｨｪ (ｨｮ 95,2%). 02ｨ 04 ﾂｨｪ06, ｨｪｨ 05ｨｨ ﾂｨｨ ｨｺ0502ｨｰ06ｨｺ ｨｨ ｨｬｨｨ020205ｨｨ ｨ 08ｨ ｨｰ ｨ 02ｨｰ ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ04ｨｬ 0502ｨｦｨｺ0602ｨｨｨｰ060406ｨｬ ( ｨｦｨｺ0602ｨｨｨｰ ｨｪｨｨ07) ｪ 72,1%. 0201ｨｪｨ ｨｺ06 ｨｮ ﾂｨ 09ｨｰｨｨ 07ｨ 02ｨｨ02ｨｪｨｰ ｨｰｨ ｨｨｨｪ0002ｨｺ02ｨｨ07 ｨｪ ｨ 02ｨｰ ｨ 0302ｨｪｨｪ06ｨｦ ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨ02ｨｦ. 00ｨ ｨｰ0208ｨｨｨ 05, 09 ｨｺ06ｨｰ060806ｨｬ ｨｰ ｨｨ ｨｨ ｨｬｨｨ020205ｨｨｨｦ ﾂｨ ｨｴ ｨｨｨｰ 09ｨｬ0203ｨ ｨｪｨｪｨｮ ｨｮ ｨ 05ｨ 01ｨ ｨｪｨｨ02ｨｬ 07ｨ 0506 ﾂ02ｨｺ ｨｦｨｪｨ (87%) ｨｨｨ 05ｨｹｨｪ06 ｨｪ02 06ｨｰ ｨｨ09ｨ ｨｹ 0906 ﾂ02ｨｰｨ ｨｪｨｨ02 Candida ｨｮ00ｨｨｨｬｨｨ ｨｨ 0505ｨｨｨｬｨｨｨｪｨ 02ｨｨ06 Candida ﾂ02ｨｪｨｨ ｨｰｨｨ ｨｨｨ ｨｺ060904ｨｬｨｨ ｨ 08ｨ ｨｰｨ ｨｬｨｨ. 0201ｨｪｨ ｨｺ06 ｨｮ 0006 ﾁ ｨｨｨｪ00ｨｨ02ｨｨ080609ｨ ｨｪ-