CAST Na Vaughan Williams Sicilian Gambit 1996 Sicilian Gambit CD-ROM CD-ROM J-GAMBIT 1Sicilian Gambit CD-ROM
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1 Guidelines for Drug Treatment of Arrhythmias (JCS 2004) a 1Sicilian Gambit 2J-GAMBIT Circulation Journal Vol. 68, Suppl. IV,
2 CAST Na Vaughan Williams Sicilian Gambit 1996 Sicilian Gambit CD-ROM CD-ROM J-GAMBIT 1Sicilian Gambit CD-ROM Sicilian Gambit Cardiac Arrhythmia Suppression TrialCAST 1 Sicilian Gambit Sicilian Gambit Sicilian Gambit - Sicilian Gambit CD-ROM 1 Sicilian Gambit 1056 Circulation Journal Vol. 68, Suppl. IV, 2004
3 3 CD-ROM Sicilian Gambit 2 Vaughan Williams Singh Vaughan Williams 3 Sicilian Gambit 2 PQQRSQT Na Na fastintermediateslow fast drug slow drug Ca K If Vaughan Williams NaK 3 Sicilian Gambit Vaughan Williams K 10 K 4 Sicilian Gambit J-GAMBIT J-RHYTHM Ia Ib Ic 1 Circulation Journal Vol. 68, Suppl. IV,
4 ATP 2 1 Na Fast Med Slow A A A I A A A A A Ca K If M 2 A 1 Na-K ATPase PR QRS JT AI 2 CD-ROM CD-ROM 1 Sicilian Gambit CD-ROM Japanese Guideline for Arrhythmia Management By Individual TherapyJ-GAMBIT 2 12 PAF PVC PAF 274 PVC PAF % CD-ROM 168 CD-ROM PVC % PAF PVC 1058 Circulation Journal Vol. 68, Suppl. IV, 2004
5 4 CD-ROM PAF 79 %PVC 71 % CD-ROM PAF 6 PVC 5 CD-ROM Sicilian Gambit 2 PAF PAF CD-ROM PVC PVC PVC CD-ROM 3 1 slow kinetics Na fast kinetics Na K Na Ca K 5 2 Ccr 50 mlmin Scr 1.3 mgdl Ccr mlmin Scr mgdl 2312 Ccr 20 mlmin Scr 2.0 mgdl mgdl 23 Circulation Journal Vol. 68, Suppl. IV,
6 mgdl mgdl 67 4 FDA Na slow drug 1 slow drug Na intermediate drug slow drug intermediate drug intermediate drug slow drug intermediate drug DC Ca K Na 1060 Circulation Journal Vol. 68, Suppl. IV, 2004
7 1 Ca Ca AHA cm 2 QOL INR Circulation Journal Vol. 68, Suppl. IV,
8 Na : Na Na Na 11 Brugada ST K Na slow Na intermediate K Na intermediate Na intermediate 1062 Circulation Journal Vol. 68, Suppl. IV, 2004
9 CTAF AFFIRM Na K Na Na Na K 2 M2 Na Brugada Na 3 20 Type 1 21 Type DC R 50 J DC Type Type 2 19 Type 1 K Circulation Journal Vol. 68, Suppl. IV,
10 DC DC Na intermediateslow drug DC 4 K Na intermediateslow drug 90 % 20 5 WPW % Circulation Journal Vol. 68, Suppl. IV, 2004
11 80 mmhg DC Valsalva 24 Ca 5 mg 10 mg 5 ATP10 mg % 25 Na 4060 % 26 DC 2 Na Ca WPW K 3 6 QRS Ca Ca Ca Ca Circulation Journal Vol. 68, Suppl. IV,
12 RBBB LAD LBBB RAD Ca Na slow Na intermediatefast Ca Na slow Na intermediatefast Na slow Na intermediatefast DAD DAD Na 2 48 Lown Grade 1 Grade 2-5 Na Circulation Journal Vol. 68, Suppl. IV, 2004
13 5 1 Na slow Na fastintermediate a aca K Na fastintermediate a Na fastintermediate a Na slow Na fastintermediate Na fast Na intermediate Na ACE A- ICD 3031 slow kinetic Na ICD fastintermediate kinetic Na Fast kinetic drug ACE A- Na 32 MADIT- ICD ACE A- 6 1 Circulation Journal Vol. 68, Suppl. IV,
14 DC 6 1 RBBBLAD Na LBBBRAD ATP Na Na DC RBBB LAD LBBB RAD ATP Na a DC a 1068 Circulation Journal Vol. 68, Suppl. IV, 2004
15 2 7 ICD ICD fast-intermediate kinetic Na K 37 ICD ICD ACE A- ICD VT CAST slow drugs ACE A- EPS ICD Circulation Journal Vol. 68, Suppl. IV,
16 ICD 7 38 QRS QRS QT QT torsade de pointestdp QT QT 39 QT 1 3 QT QT DC 3 DC ACLS DC, DC QT QT 8 DC 3 DC ACLS QT DC DC QT Mg QT QT 1070 Circulation Journal Vol. 68, Suppl. IV, 2004
17 9 QT QT ICD IDC QT QT Brugada QT ICD ICD ICD ICD ICD 41 QT QT Brugada ICD mgkg mgkg 3 A Circulation Journal Vol. 68, Suppl. IV,
18 ATP 48 Ca 49 Na WPW Na WPW Ca Na DC Jkg 10 DC ATP* Na DC 1072 Circulation Journal Vol. 68, Suppl. IV, 2004
19 Ca Ca ATP Na K 52 Ca QT torsade de pointestdp 1 a b 200 d 2 RBBBLAD Ca Na 51 LBBBRAD 50 Ca Na Na RBBBLAD Ca Na LBBBRAD Na 54 Ca Na c 200 Circulation Journal Vol. 68, Suppl. IV,
20 DC Na QRS RBBBLAD Ca LBBBRAD ATP Na Na Na DC RBBBLAD Ca Na 51 LBBBRAD Ca Na 51 Ca K T DC RBBBLAD Na fast LBBBRAD Ca Na intermediateslow ATP Na intermediateslow Na intermediateslow DC 1074 Circulation Journal Vol. 68, Suppl. IV, 2004
21 QT Tdp QT 3 Ca DC 2 Jkg Sicilian Gambit J-RHYTHM Circulation Journal Vol. 68, Suppl. IV,
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23 Lancet 1997; 349: Gorgels AP, van de Pool A, Hofs A, et al. Comparison of procainamide and lidocaine in terminating sustained monomorphic ventricular tachycardia. Am J Cardiol 1996; 78: The CASCADE investigators. Randomized antiarrhythmic drug therapy in survivors of cardiac arrestthe CASCADE study. Am J Cardiol 1993; 72: The Antiarrhythmics versus Implantable Defibrillators AVIDInvestigators. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med 1997; 337: Gregoratos G, Cheitlin MD, Conill A, et al. ACCAHA Guidelines for Implantation of Cardiac Pacemakers and Antiarrhythmic Devices: Executive Summary. A report of the American College of CardiologyAmerican Heart Association Task Force on Practice Guidelines. Circulation 1998; 97: Pacifico A, Hohloser SH, Williams JH, et al. Prevention of implantable-defibrillator shocks by treatment with sotalol. N Engl J Med 1999; 340: :.:, :,., 1996; p Schwartz PJ, Priori SG, Napolitano C. The long QT syndrome. Cardiac Electrophysiology. From Cell to Bedside. Third edition.editors: ZipesJalife Saunders p Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 3: adult basic life support. The American Heart Association in collaboration with the International Liaison Committee on Resuscitation. Circulation 2000; 102: I-22-I-59 41,,,.. Jpn Circ J 2001; 65(Suppl V): Priori SG, Aliot E, Blomstrom-Lundqvist C, et al. Task force on sudden cardiac death of the European Society of Cardiology. Eur Heart J 2001; 22: ,,,.. Jpn Circ J 2001; 65(Suppl V): Benditt DG, Benson DW Jr, Kreitt J, et al. Electrophysiologic effects of theophylline in young patients with recurrent symptomatic bradyarrhythmias. Am J Cardiol 1983; 52: Alboni P, Ratto B, Cappato R, et al. Clinical effects of oral theophylline in sick sinus syndrome. Am Heart J 1991; 122: Atarashi H, Endoh Y, Saitoh H, et al. Chronic effects of cilostazol, a new antithrombotic agent, in patients with bradyarrhythmias. J Cardiovasc Pharmacol 1998; 31: ,,,. 2000; 16: Losek JD, Endom E, Dietrich A, et al. Adenosine and pediatric supraventricular tachycardia in the emergency department: Multicenter study and review. Ann Emerg Med 1999; 33: ,,,. verapamil. 1995; 11: Janousek J. Paul T for the working group on pediatric arrhythmias and electrophysiology of the association of European pediatric cardiologists: Safety of oral propafenone in the treatment of arrhythmias in infants and childreneuropean retrospective multicenter study. Am J Cardiol 1998; 81: Fish FA, Gillette PC, Benson DW Jr for the pediatric electrophysiology group: Proarrhythmia, cardiac arrest and death in young patients receiving encainide and flecainide. J Am Coll Cardiol 1991; 18: Maagnes P, Tipple M, Fournier A. Effectiveness of oral sotalol for treatment of pediatric arrhythmias. Am J Cardiol 1992; 69: Leenhardt A, Lucerty V, Denjoy I, et al. Cathecholaminergic polymorphic ventricular tachycardia in children. A 7-year follow-up of 21 patients. Circulation 1995; 91: Sumitomo N, Harada K, Nagashima M, et al. Catecholaminergic polymorphic ventricular tachycardia: Electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden death. Heart 2003; 89: Guccione P, Paul T, Garson A Jr. Long term follow-up of amiodarone therapy in the young. J Am Coll Cadiol 1990; 15: Moss AJ, Zareba W, Schwartz PJ, et al. Effectiveness and limitation of beta-blocker therapy in congenital long-qt syndrome. Circulation 2000; 101: Circulation Journal Vol. 68, Suppl. IV,
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