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1 Enterovirus Infection in Children Fukushima Medical University School of Medicine
2 CA1 CA19 CA4 CA3 PV3 CA13 CA18 CA17 CA24v CA11 CA15 CA20 CA24 CA21 CA22 E16 PV1 PV2 E31 E5 E15 E24 E6 E27 E18 E17 E13 CB1 E14 E32 E19 CB5 E7 E12 CB2 E11 E29 CB4 E1 E21 E9 E3 CB6 E26 E4 CA9 E30 EV69 E20 E25 CB3 E33 CA10 CA6 CA12 CA5 CA7 CA8 EV68 EV70 CA16 CA14 CA2 E2 EV71 C B D A Genetic distances Cluster
3 RS
4
5
6 C-1 C-4 C-2 C-2 C-3 C-1 C-1 B-1 B-3 B-4 B-5 Isolation number in Fukushima Isolation number in Japan
7 CV-A16 EV71(BrCr) India/R13223-IND-01 USA/2228-NY72/72 USA/6910-OK87/87 75 USA/2235-NY77/77 74 Kanagawa/V-3478/82 Kanagawa/V-4879/84 Bulgaria/258/75 Ehime/2118/78 95 Aichi/70 Nagoya-73 Nagoya/70 USA/1011-ND79/79 Aichi/3059/73 USA/2229-NY76/76 Ehime/209/78 USA/10181-MN78/78 USA/2231-NY77/77 Hungary-78 Kanagawa/V-4110/83 Kanagawa/V-4014/83 Kanagawa/V-4185/83 Fukushima/29/83 Fukushima/419/85 Fukushima/135/84 Aichi/3359/83 Taiwan/80/73 Taiwan/244/86 88 Taiwan/240/86 Taiwan/T86236a/86 Epsom/10620/99 97 Fukushima/10350/03 Kanagawa/HO793f/03 Kanagawa/HO793ts/03 Kanagawa/P-2265/03 Fukushima/10013/03 Fukushima/10100/03 Singapore/4915/99 Australia/4F/AUS/4/99 Malaysia/SK026/97 Malaysia/SK036/97 Kanagawa/V-14457/97 Singapore/3526/98 Malaysia/SK-EV006/97 SAR/MY104-9/97 Singapore/13/98 Fukushima/3302/93 Fukushima/1448/ /85 Kanagawa/V-4083/83 71 Ehime/0445/90 Fukushima/1478/89 Aichi/1/89 Kanagawa/V-9281/90 Kanagawa/V-7949/98 USA/7633-PA87/87 USA//7673-CT87/87 USA/8102-WA87/87 77 USA/1413-CA87/87 USA/MS/7423/87 Singapore/5511/00 Fukushima/10104/03 Kanagawa/HC29F/00 79 Kanagawa/P-530/00 Hyogo/1610/00 Fukushima/8269/00 Kanagawa/P-739/00 Kanagawa/P-583/00 Kanagawa/P-499/00 Fukushima/8272/00 Hyogo/1580/00 SAR/CN9502/00 93 SAR/S21082/00 Singapore/5536/00 SAR/CN0942/00 Singapore/2027/01 Singapore/5926/00 Singapore/5859/00 Taiwan/7008/98 Singapore/18/97 Osaka/C7/97 Kanagawa/V-14429/97 Taiwan/J1263P4/98 Taiwan/5929/98 Taiwan/1394/98 B-1 B-5 B-3 B-2 B-4 Group B
8 AY (97/ /99) Sweden (1999) AF (Berlin/8134/65) 79 AF (Potsdam/0412/76) Germany (1974,1976) AF (Halle/0352/74) E13-VP1 (Del Carmen) AF (Potsdam/0529/79) Germany AJ (CF957-95) AJ (CF ) France (1995) AF (42/99)Sweden AJ30925 (/pe/roma96) Italy (1996) AF (Dresden/420/01) AY (Kassel/310/01) AF (Krefeld/679/00) Germany (2001) AB (02-204SFH2) AB (02-206NPH3) AB (02-216SFR1) 52 AB (02-182NPR2) AB (02-185SFC2) Fukuoka (2002) AB (02-184SFC2) AB (02-205SFH2) AB (02-201FCC1) AB (ONO2-2R) Hiroshima (2002) AB (02-131SFR1) Fukuoka (2002) Fukushima AJ (CF ) France (2000) AF (Stuttgart/435/00) 38 AF (Magdeburg/377/01) 24 AF (Ulm/573/00) Germany ( ) 2 33 AF (Chemniz/501/00) 2 24 AY (Weissenfels/2000/DEU) AJ (CF ) AJ (CF ) France (2001) 0 1 AB (19/Fukushima/01) AY (KOR-E ) Fukushima (2001) 47 AY (KOR-E ) AY (KOR-E ) 13 AY268568(KOR-E ) AY (KOR-E ) AY (KOR-E ) 5 AY (KOR-E ) 28 AY (KOR-E ) AY (KOR-E ) Korea (2002) 2 AY (KOR-E ) 30 AY (KOR-E ) AY (KOR-E ) 0 AY (KOR-E ) 0 AY268578(KOR-E ) 0 AY (KOR-E AY (KOR-E ) 67 AY (KOR-E ) 0.10 Nucleotide distance 0.00 Virus () in CSF Virus () in CSF
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10 γ et al et al
11 et al et al Enterovirus Infection in Children Fukushima Medical University School of Medicine
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Pharmaceutical Segment 12 13 14 Pharmaceutical Segment 15 16 Pharmaceutical Segment 17 GERMANY CHINA JAPAN U.S.A. KOREA SINGAPORE 18 Pharmaceutical Segment 19 20 Pharmaceutical Segment 21 22 Pharmaceutical
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食品、飲料、製薬、医療用途向けシーリングソリューション
食品 飲料 製薬 医療用シーリングソリューション Your Partner for Sealing Technology 2 4 6 7 10 20 21 28 www.tss.trelleborg.com/jp 3 4 5 6 7 8 9 10 page 29 11 12 page 28 13 14 page 30 15 16 page 30 page 23 17 18 19 20 21 22 23