AG 1/16 AA ALDH ALDH-E2 ALDH-E a2001b ALDH-E ALDH-E2 ALDH-E2 ALDH-E2 ALDH-E2 ALDH-E ALDH-E ALDH-E2 3,
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1 5 2Bulletin of Tokyo University and Graduate School of Social Welfare pp65-71 (2015, 3) %2037.7% 4 7.5% % % % ALDH-E ; Ehrig et al., ADHMEOS 2 ALDH -CoA -CoA ALDH-E a GG 1 AG 2 AA ALDH-E2 GG 65
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3 顔貌とアルコールパッチテスト反応 調査方法 程度を観察し 引き続いて 10 分後に 発赤の程度を再観察 調査は 201X 年 11 月に実施した した 調査対象の学生に 馬場 1999 に基づいて独自に作成し 発赤の程度は 発赤なし 1 点 やや発赤 10 分後に発赤 た縄文人および弥生人の顔貌の特徴に関する質問紙 表 1 が強まる 2 点 顕著な発赤 3 点 の 3 段階で評価した を手渡し 15 項目の質問に対してどちらに近いか また 質問紙に印刷された顔サンプルのどれに類似しているか 事前の説明は行わずに 任意の自己評価によって回答して 説明と同意 個人情報の保護 対象者には 本研究の趣旨 結果の評価および論文や学 もらった 会発表の際の利用 さらに個人情報の取り扱い方法を記載 質問紙に対する回答時間内に 後述するアルコールパッ した文章を質問紙と同時に配布し また 回収された回答 チテストを実施し 皮膚の発赤の有無を観察した さらに 用紙の保管と研究がまとまった段階での破棄などについ 回答用紙を提出する際に頭のサイズを測定し 縦 前後 お て 口頭による補足説明を行い 調査協力の同意を得た よび横 左右 の長さの比を算出した なお 本論文の作成に当たり 関係者以外には得られた 情報から個人の特定ができないよう 可能な限り配慮した アルコールパッチテスト 統計処理 アルコールパッチテストは 栗原 2000 の手順と判定方 法に従って行った カットバンの脱脂綿部分に消毒用エタ 15 項目の質問への回答結果 頭のサイズ 縦と横の比 ノール 約 70 重量 を数滴垂らし 前腕の肘関節部の皮膚 顔サンプルとの類似性とアルコールパッチテスト結果と に貼ってもらった 7 分後にカットバンを剥がして発赤の の相関性を検討した 質問に対する回答では 左側 縄文 表 1 調査対象者に配布した質問紙 チェックリストは馬場 1999 のリストを基に作成 顔貌の CG は東京大学工学部原島研究室より 67
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5 N= N= ALDH-E ALDH-E ALDH-E /4 10 ALDH-E ALDH-E2 ALDH-E2ALDH-E ALDH-E2 ALDH-E ALDH- E
6 ALDH-E2 1986:.,. 1999: : Ehrig, T., Bosron, W.F. and Li, T.K. 1990Alcohol and aldehyde dehydrogenase. Alcohol Alcohol. 25, :. 50, :. 63, a:. 864, b:. 36, : :. 55, :. 40, : 54, :.,. 2006: :. 31, :.,, pp :.,, pp : ALDH2. 42, :. 35,
7 Are There any Correlations between the Face Profiles and the Results of Ethanol Patch Test in Japanese? Hisashi KURIBARA Junior College, Tokyo University of Social Welfare, Sano-cho, Isesaki-city, Gunma , Japan Abstract : The purpose of this study was to assess the relationship between the face profiles of Japanese (Jomon type and Yayoi type) and the results of ethanol patch test (non flash, mild flash and flash) in university students (53 males and 202 females). The proportions of non flash and mild flash + flash (male: 54.7% and 45.3%, respectively, female: 60.4% and 59.6%, respectively) were almost the same as the standard proportion. In males, although the correlation coefficients between the results of ethanol patch test and face profiles were greater than 0.25 in the items of eyebrow (0.286) and cheekbone (0.251), and smaller than in earlobe (-0.511), shape of mouth (-0.282) and ratio of longitude and side of head (-0.324). However, the absolute values of correlation coefficient for other items were smaller than 0.25 in both males and females. These results suggest that the prediction of acetaldehyde dehydrogenase (ALDH-E2) activity is hard from the face profiles, namely Jomon type and Yayoi type. (Reprint request should be sent to Hisashi Kuribara) Key words : Face profiles of Japanese, Alcohol patch test, Old Mongoloid (Jomon type), Neo Mongoloid (Yayoi type) 71
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