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45 Minamata Disease

46 90 50ppm 4 D. Hunter R. Bomford D. Russell Quart. J. Med Hunter Russell Neurol. Neurosurg. Psychiat F. Henke O. Lubarsch 13 2 A. Pentschew Hunter Von Oettingen 1954 Hunter 2 Hunter 34 Hunter McAlpine Lancet 9 40

47 NIH National Institutes of Health Kurland NIH 41

48 ppm ,000ppm

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52 , ,500 6,500 46

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56 World Neurology

57 NIH T World Neurology Jernelov

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61 NIH PHS Public Health Service NIH

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63 ( ) ( ) ( ) ( )

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65 fetal congenital ppm

66 , ppm 4 80ppm 920ppm 430ppm 1855ppm 3 60

67

68 CH 3 HgSCH CH 3 HgCl PHS

69 WPCF 2 WPCF WPCF 63

70 , ppm ppm ,849 19,

71 ppm 1 60km WHO FAO 50ppm g/g 0.4ppm g/ml 0.3mg % 200ppm ppm 0.2 2ppm 50ppm 0.2ppm WHO/FAO 50ppm ppm 23 65

72 WHO 50 ppm 0.2 ppm 0.4 Tejning Bakir Kojima 0.2 mg/ / 0.3 mg 60 kg 5 g/kg/ WHO WHO ppm ppm 1 1kg 3 7 g ppm 82.6 ppm WHO 101 WHO ppm mg 3.3 g/kg 2003 FAO WHO JECFA g/kg / JECFA 2.0 g/kg / mg 50 kg ppm 0.3 ppm

73

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77 ISO 1) 2) 3) PCB 1) 71

78 2) 1) 2) 3) 72

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115 ) 2) PR 109

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125 ISO ISO International Standardize Organization ISO14000 JIS 3) )

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147 &A 1995 NHK NHK NHK

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