労働 Health Care Quality Indicators Project - 6 data collection update report (OECD Health Working Paper No. 29) 5-Oct-7 HPV-18 ( 99 HPV 8 HPV 9 B B C

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2 労働 Health Care Quality Indicators Project - 6 data collection update report (OECD Health Working Paper No. 29) 5-Oct-7 HPV-18 ( 99 HPV 8 HPV 9 B B C 8 5 >5 1 1 / Baseline reference ( B 9.1 B 9 F.X. Bosch et all. in J. Clin Pathol 2 2

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4 HPV Assembly of Virus-Like ike Particle (VLP) HPV DNA L1 VLP HPV HPV mrna L1 19 HPV genotype Other Global cervical cancer coverage by HPV high risk (cumulative) Adapted from Munoz N et al. Int J Cancer 4; 111: most common s in squamous cell carcinoma by region All all cases Asia North America and Australia Africa Europe South and Central America Clifford et al, BJC, 3b 24 4

5 HPV8 6 (97.9 CI) HPV16 18 HPV Paavonen J et al. Lancet 7;369: E. M. de Villiers et al., Virology rs HPV-16 GMC EU/ml HPV Schwarz TF et al. J Clin Oncol 6;24(18S) Harper et al. Lancet 6; 367: Schwarz TF et al. J Clin Oncol 6;24(18S) sexual debut in Japan Data source: Survey of consciousness and behavior about sex in children and students, 2. Metropolitan sexual education society of children and students in elementary schools, junior high schools and high schools, Tokyo. 2. 5

6 ACIP Recommendation 6111 GARDASIL H 4 6,11,16,18 CDC s Vaccine for Children, VFC ( ) VFC CDC Advisory Committee for Immunization Practice, ACIP VFC 32 Ontario, Canada Government Will Offer HPV Vaccine To 8th Grade Girls August 3, 7 1: p.m. EST Valerie Chang - AHN News Writer Toronto, ON (AHN) - The province of Ontario will begin offering the human papillomavirus (HPV) vaccine to girls in the 8th grade, at no cost, starting this fall. HPV, which is sexually transmitted, causes cervical cancer. Girls in Ontario will have the option to get the Gardasil vaccine at no cost, but will not be required to do so. Public health nurses will provide the vaccine, which is comprised of a three-shot course of treatment, at schools. Gardasil prevents four strains of HPV that cause about 7 percent of cervical cancer cases. In announcing that it will provide HPV vaccines for girls, Ontario joins the province of Nova Scotia, which announced its vaccination program for 7th grade girls in June. Prince Edward Island also plans to offer the vaccine to 6th grade girls. Copyright AHN Media Corp - All rights reserved. Redistribution, republication. syndication, rewriting or broadcast is expressly prohibited without the prior written consent of AHN BCG B A HI b 2 6

7 CDC 34 1 Outbreak b Hib MMR* * MMR (Pw) (Pa) (Pa) B 1 BCG (<3) Hib Reference: Nature medicine Vo.11, No.4 S12(Table1) 7

8 Vaccine For Children Cervical Cancer Prevention Vaccinate your daughter, screen yourself! Dr.Kinny (USA) in EUROGIN 7, Monaco Thank you for your attention! 8

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HPV HPV HPV HPV 7 HPV 8 9 HPV 3 HPV HPV HPV , Becker Ajzen H 3 26 3 Journal of Junshin Gakuen University, HPV Faculty of Health Sciences Vol.3, March 2014 99 HPV Knowledge of and attitudes towards human papillomavirus vaccinations among mothers who have daughters

労 働 Health Care Quality Indicators Project - 6 data collection update report (OECD Health Working Paper No. 29) 5-Oct-7 HPV-18 ( 99 HPV 8 HPV 9 B B C

労働 Health Care Quality Indicators Project - 6 data collection update report (OECD Health Working Paper No. 29) 5-Oct-7 HPV-18 ( 99 HPV 8 HPV 9 B B C