LABIO21_5
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- のぶあき さわまつ
- 7 years ago
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3 Helicobacter hepaticus H.rodentium H.bilis Pasteurella multocida P.multocida Pasteurella multocida Rattus norvegicus LABIO 21 JULY
4 LABIO 21 JULY LEC 7 3 1,
5 TEXT 129 LABIO 21 JULY
6 LABIO 21 JULY LIF Thomson 2, LIF
7 MHC MHC MHC LABIO 21 JULY
8 LABIO 21 JULY
9 Hot Corner LABIO 21 JULY
10 LABIO 21 JULY
11 Hot Corner LABIO 21 JULY
12 LABIO 21 JULY
13 LABIO 21 JULY Hot Corner
14 SOT FDA San Francisco Moscone Convention Center 40 CRO in vitro in vivo in vivo 14 LABIO 21 JULY 2001
15 in vitro in vitro in vitro 1996 SOT Continuing Education Course Screening Pharmaco- /ToxicogenomicsCombinatorial ChemistryHigh-Throughput Screeningtoxicology Computational Toxicology FDA/CDER Dr. Contrera Bristol-Myers Squibb Dr. Durham IT Computer Quantitative Structure Activity Relationship: QSAR Computational Predictive Program LABIO 21 JULY
16 CleavelandWashington D.C. San Francisco San Francisco California whole body 16 LABIO 21 JULY 2001
17 Information on Overseas Technology Information Helicobacter hepaticus, H. rodentium H. bilis H. rodentium H. rodentium H. H. bilis bilis PCR Tac:SWfBR H. IgG hepaticus 82%H. rodentium 17 PCR H. hepaticus, H. rodentium H. bilis PCR ELISA IgG 88% H. bilis 94% H. hepaticus 98%H. rodentium 86%H. bilis 95% 1 PCR 6 H. hepaticus H. rodentium IgG ELISA 98%100% 34% 44% H. hepaticus H. rodentium PCR Information on Overseas Technology 60%44% H. hepaticus 43 H. hepaticus H. rodentium %81%H bilis 4 keyword LABIO 21 JULY
18 Information Pasteurella multocida P. multocida Information on Overseas Technology Pasteurella multocida PMT P. multocida CN PMT CN 24 PMT/CN PMT/CN PMT/CN PMT/CN Day 0 Day Day 56 P. multocida Day 60 Day keyword PMT/CN CN IgG IgM IgG IgAIgG g PMTCN PMT CN Information Pasteurella multocida Pasteurella multocida PMT PMTIPMT PMT IPMT IPMT ml P. multocida BT 10 IPMTg PMT ELISA BT IPMT 14PMT IgG IgA PMT 18 LABIO 21 JULY 2001
19 Information on Overseas Technology BTIPMT 21 PMT 28g Information PMT IPMT BT keyword P. multocida PMT Information on Overseas Technology PCR DNA 9510 ph DNA DNA PCR 19 PCR 89 keyword LABIO 21 JULY
20 Information on Overseas Technology Information (Rattus norvegicus) SHR QTL SHR F1 F1 SHR BC1 SHR F1 F1 F1 BC1 72 QTL BC D2Mit2 Fgg X SHR á keyword Information CO 2 10C57BL/6 n=40 CO 270% CO 2/30% O 270% CO 2/30% O 2 100% CO 2100% CO 2 100% CO 2 100% CO 2 70% CO 2/30% O 2 100% CO 2 MCV MCH CD8 + T CO 2 CO 2 / keyword 20 LABIO 21 JULY 2001
21 WHHL WHHLWatanabe Heritable HyperlipidemicRabbit origin Ch Ch 20 Ch Ch Ch 10 Mutant WHHL origin 1973 LABIO 21 JULY
22 Mutant Mutant Ch 40 Ch Ch F3 3 1 WHHL ,000 WHHL 3 6 WHHL F Mutant Ch WHHL 22 LABIO 21 JULY 2001
23 WHHL Data Data 1976 l,2 Ch 6 give Up 1979 Ch Mutant 6 HLR WHLWatanabe Hyperlipidemic Suggestion Heterozygote WHL 1980 Atherosclerosis Atherosclerosis WHL Heritable WHHL WHHL WHHL 4050 Texas Goldstein LDL Pathway LDL FH Ch LDL Ch Ch Ch FamiliaI Hypercholesterolemia: FH Ch Homozygote 20 LDL WHHL LABIO 21 JULY
24 WHHL LDL Goldstein WHHL 1985 WHHL NIH National Institute of Health WHHL WHHL WHHL WHHL 1990 WHHL WHHL 24 LABIO 21 JULY 2001
25 LABIO 21 JULY
26 26 LABIO 21 JULY 2001
27 ELISA Parainfluenza virus Type 3 Sendai virus Clostridium piliforme Tyzzer Sendai virus HI IFA HI PCR PCR PCR LABIO 21 JULY
28 Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books Books kgAdrenaline BOOK Epinephrine 1927 Adrenaline Adrenaline AdrenalineEpinephrine Adrenaline LABIO 21 JULY 2001
29 LABIO ,011 62,549( LABIO 21 No.5No LABIO 21 JULY
30 societies-j/alt/15.html Brisbane Australia Boston USA St. Louis Sydney, Australia. j 30 LABIO 21 JULY 2001
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ISSN 1345-9147 Japanese Society of Laboratory Animals LABIO 21 18 No. OCT. 2004 Tel. 03-3864-9730 Fax. 03-3864-0619 http://group.lin.go.jp/jsla/ E-mail: jsla@group.lin.go.jp 4 5 6 11 15 18 22 26 30 31
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No. 42 OCT. 2010 Tel. 03-5215-2231 Fax. 03-5215-2232 http://www.nichidokyo.or.jp/ E-mail: jsla@nichidokyo.or.jp 4 6 9 12 16 20 24 28 32 35 38 41 43 44 45 46 LABIO 21 OCT. 2010 3 LABIO 21 OCT. 2010 4 LABIO
ISSN 1345-9147 Japanese Society of Laboratory Animals LABIO 21 20 No. APR. 2005 Tel. 03-3864-9730 Fax. 03-3864-0619 http://group.lin.go.jp/jsla/ E-mail: jsla@group.lin.go.jp 4 5 7 8 11 18 21 26 33 35
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実験動物の微生物モニタリングに関する指針 公私立大学実験動物施設協議会平成 10 年 5 月 26 日制定平成 25 年 5 月 14 日改訂平成 27 年 4 月 10 日改訂 本指針は 公私立大学実験動物施設協議会 ( 協議会 ) 加盟各施設の実験動物の微生物学的検査体制の充実を目的として 各施
実験動物の微生物モニタリングに関する指針 公私立大学実験動物施設協議会平成 10 年 5 月 26 日制定平成 25 年 5 月 14 日改訂平成 27 年 4 月 10 日改訂 本指針は 公私立大学実験動物施設協議会 ( 協議会 ) 加盟各施設の実験動物の微生物学的検査体制の充実を目的として 各施設で飼育する実験動物の微生物学的清浄度の推奨基準を設け 動物実験の信頼性の向上を図ろうとするものである
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No. 46 OCT. 2011 Tel. 03-5215-2231 Fax. 03-5215-2232 http://www.nichidokyo.or.jp/ E-mail: jsla@nichidokyo.or.jp 4 6 9 13 18 23 28 31 35 38 39 40 41 43 44 45 46 LABIO 21 OCT. 2011 3 LABIO 21 OCT. 2011
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