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1 Six years of experiences at the U.K. MRC Laboratories, The Gambia, in West Africa Koya ARIYOSHI Jonathan Weber Medical Research Council MRC Laboratories, The Gambia HIV Virologist/Immunologist MRC MRC MRC MRC km Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University ( Sakamoto, Nagasaki) 5

2 134 m HIV HIV CD4 HIV HIV-2 200km 1990 HIV 6

3 135 HIV-2 HIV HIV-2 HIV-2 HIV-2 1 MRC MRC Brian Greenwood 10 1 Plasmodium falciparum A Hill HLA HLA I B53 7

4 mg/kg cm RSV HIV HIV-1 HIV-1 Magnesium Trisilicate 8

5 137 WHO UNICEF Greenwood MRC Hilton Whittle Whittle H.C., Ariyoshi K., Rowland-Jones S.: HIV-2 and T cell recognition. Curr Opin Immunol. : , Hill A.V., Allsopp C.E., Kwiatkowski D., et al.: Common west African HLA antigens are associated with protection from severe malaria. Nature : , Whittle H.C., Inskip H., Hall A.J., et al.: Vaccination against hepatitis B and protection against chronic viral carriage in The Gambia. Lancet : , Mulholland K., Hilton S., Adegbola R., et al.: Randomised trial of Haemophilus influenzae type-b tetanus protein conjugate vaccine for prevention of pneumonea and meningitis in Gambian infants. Lancet : ,

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