Med. J. Kagoshima Univ., October, 2015 Reduced port surgery にて腹腔鏡下盲腸切除術を施行した虫垂粘液嚢胞腺腫の一例 新田吉陽 馬場研二 益満幸一郎 盛真一郎 有留邦明 夏越祥次 鹿児島大学大学院医歯学総合研究科腫瘍学講座消化

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Reduced port surgery にて腹腔鏡下盲腸切除術を施行した 虫垂粘液嚢胞腺腫の一例 新田吉陽 馬場研二 益満幸一郎 盛真一郎 有留邦明 夏越祥次 鹿児島大学医学雑誌 2015 年 10 月

2015 10 Med. J. Kagoshima Univ., October, 2015 Reduced port surgery にて腹腔鏡下盲腸切除術を施行した虫垂粘液嚢胞腺腫の一例 新田吉陽 馬場研二 益満幸一郎 盛真一郎 有留邦明 夏越祥次 鹿児島大学大学院医歯学総合研究科腫瘍学講座消化器 乳腺甲状腺外科学分野 連絡先新田吉陽 890-8544 鹿児島市桜ヶ丘 8-35-1 鹿児島大学大学院医歯学総合研究科腫瘍学講座消化器 乳腺甲状腺外科学分野 TEL : 099-275-5361 / FAX : 099-265-7426 A Case Report of Appendiceal Mucinous Adenoma Resected by Reduced Port Surgery Yoshiaki Shinden*, Kenji Baba, Koichiro Masumitsu, Shinichiro Mori, Kuniaki Aridome, Shoji Natsugoe Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences (Received July. 30; Revised Aug. 18; Accepted Sept. 19) *Address to Correspondence Yoshiaki Shinden Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan Tel.: +81-99-275-5361; Fax: +81-99-265-7426 E-mail: yoshinden@gmail.com Abstract Mucinous cystadenoma of the appendix is a relatively rare disease that is a variant of appendiceal mucocele. Because of the risk for peritoneal pseudomyxoma by rupture of appendiceal mucocele, careful maneuvering is required during surgical resection. Although there are many case reports of laparoscopic surgery for appendix mucocele, there are only a few reports of reduced port surgery (RPS). We report a case of mucinous cystadenoma of the appendix that was safely resected by RPS. A 73-year-old man was diagnosed as having mucinous cystadenoma of the appendix and underwent laparoscopic-assisted partial cecectomy. RPS is satisfactorily feasible for the resection of an appendiceal mucocele that requires a precise surgical maneuver. Key words: Appendiceal mucocele, Mucinous cystadenoma of the appendix, Reduced port surgery

34 緒言 1 2 3 4 5 Reduced port surgery RPS 6 7 RPS 5 8 RPS 症例 73 CEA volcano sign 1 2 3cm 3 CT 4 MRI 3cmT2 5 25mm EZ Hakko 5mm 2 5mm RPS 6 7 8 8 考察 0.2~0.4 3 9 9 20 30 1 4, 10 CT 11 1 12 13 2 3 4 8 4 8 8

Reduced port surgery 35 図 1 : Colonoscopy There is a lesion resembling a submucosal tumor in the cecum. The tumor exhibits the volcano sign in the appendiceal opening (white arrows). 図 2 : Endoscopic ultrasonography A cystic lesion is noted in the lumen. No tumorous tissue is present in the cystic lesion.

36 図 3 : Barium enema examination A 3-cm spherical lesion with smooth margins is noted in the cecum. The appendix is not visualized on radiologic examination. 図 4 : Computed tomography Fluid accumulation and expanded appendix is noted. No enhanced cystic component is present.

Reduced port surgery 37 図 5 : Magnetic resonance imaging (T2-weighted image, coronal plane) A 3-cm cystic structure is noted in the ileocecal region. No solid component is present within the cyst. 図 6 : Surgical wounds The EZ access port was inserted through the umbilicus, and a 5-mm port was inserted into the right lower quadrant of the abdomen.

38 図 7 : Macroscopic image of the resected specimen A spherical tumor is present in the expanded root of the appendix. 図 8 : HE-stained pathologic photomicrograph Papillary proliferation of a hyperplastic glandular duct with slight atypia is noted.

Reduced port surgery 39 3 13 5 4 13 RPS RPS RPS single port surgery SPS needle scopic surgery 7 RPS RCT SPS SPS 15 RPS SPS RPS 結論 RPS RPS 文献 1. 9. 2008; 105 40-46. 2 Moreno SG, Shmookler BM, Sugarbaker PH. Appendiceal mucocele; Contraindication to laparoscopic appendectomy. Surgical endoscopy 2009; 12 : 1177-1179. 3 Dhage-Ivatury S, Sugarbaker SG. Update on the surgical approach to mucocele of the appendix. Journal of the American College of Surgeons 2006; 202 : 680-684. 4,,,,,. 9. 2012; 73 395-399. 5,,,,,.. FRONTIER 2012; 5: 74-79. 6,,,,,. reduced port surgery. 2013; 67: 237-240. 7,. Reduced Port Surgery. 2013; 2013-'14: 169-173. 8 Fujino S, Miyoshi M, Noura S, Shingai T, Tomita Y, Ohue M et al. Single-incision laparoscopic cecectomy for low-grade appendiceal mucinous neoplasm after laparoscopic rectectomy. World journal of gastrointestinal surgery 2014; 6: 84-87. 9,,,,,. 11. 2003; 64: 673-677. 10,,. 1. 2010; 72: 1113-1116. 11,,.. 2002; 47: 534-538. 12 Panarelli NC, Yantiss RK. Mucinous neoplasms of the appendix and peritoneum. Archives of pathology & laboratory medicine 2011; 135: 1261-1268. 13 Khan MR, Ahmed R, Saleem T. Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature. Journal of medical case reports 2010; 4: 129. 14,,,,,.. 2011; 16: 337-341. 15 Frutos MD, Abrisqueta J, Lujan J, Abellan I, Parrilla P. Randomized prospective study to compare laparoscopic appendectomy versus umbilical single-incision appendectomy. Annals of surgery 2013; 257: 413-418.