食用以外に利用される豚について 齋藤敏樹 ( 日本生物科学研究所 ) Saitoh, T. (2009). Nutlization of a swine other than food ALL about SWINE 35, 14-20 1 2 3 3 12 160 180 kg 12 60 80 kg 12 30 kg NIBS Fig. 1 1995 2007 Table 1 2007 1,300 NIBS Fig. 2 PubMed 1995 1998 2001 2004 2007 10,034,695 762 2,079 22,646 1,951 9,812,055 1,677 3,081 17,634 1,584 8,708,608 2,744 1,829 17,838 2,155 8,812,943 15,232 1,358 12,759 2,248 6,208,830 23,682 1,301 12,376 3,462 2008 All about SWINE No. 35 2009 14
2NIBS 1967 1988 CSK 3 20kg 10 1998 NIBS SLA DRBI(D/DDQA(D/D DQBSO9 S10/S10 Table 2 22 1,2 E 1 2 1,2,5 2,5 15
Vol.20, No.6, 2008 Fig. 3 6 20 kg Table 3 21 114 4.4 3.4 5 4 NS Table 4 5 Table 6 7 EDTA 2K 8 20.5 2.3 52 114.0 1.5 40 4.4 1.5 40 3.4 1.3 g n=32 452.0 95.5 n=32 403.0 75.3 3 n=9 5 n=9 7 n=9 10 n=9 WBCx10 2 counts/l 114 16 109 8 129 21 99 16 RBCx10 4 counts/l 861 72 892 73 877 80 898 135 HGBg/dL 14.4 1.0 15.9 0.7 15.3 0.7 16.9 1.6 HCT% 47.0 2.8 49.9 2.3 47.9 2.1 MCVfL 55 4 56 4 55 5 MCHpg 16.8 1.3 18.0 1.5 17.5 1.7 MCHC% 30.6 0.5 31.9 0.7 31.9 0.6 3 n=9 5 n=9 7 n=9 10 n=9 WBCx10 2 counts/l 125 24 122 21 118 17 108 14 RBCx10 4 counts/l 840 57 943 95 924 47 888 77 HGBg/dL 13.4 0.7 16.9 0.6 15.7 0.9 16.8 1.4 HCT% 44.4 1.8 52.9 2.1 49.6 2.9 MCVfL 53 3 56 4 54 4 MCHpg 16.0 1.1 18.0 1.8 17.0 1.1 MCHC% 30.1 0.8 31.9 1.0 31.6 0.4 All about SWINE No. 35 2009 16
17 3 n=9 5 n=9 7 n=9 10 n=9 LDHIU/L ASTIU/L ALTIU/L ALPIU/L LAPIU/L -GTIU/L UNmg/dL CREmg/dL GLUmg/dL TBmg/dL Camg/dL IPmg/dL UAmg/dL TCHOmg/dL FCHOmg/dL E/T TGLmg/dL PLmg/dL NEFAmEq/dL TPg/dL ALBg/dL A/G 868 52.0 67.0 685 163.0 97.96 5.2 0.504 105 0.344 11.65 9.51 2 82.3 19.4 0.76 40.0 104 0.216 5.98 4.18 2.33 162 15.4 14.6 238 32.3 33.23 1.4 0.057 20 0.087 0.57 0.98 2 10.4 3.2 11.2 6 0.096 0.26 0.22 0.24 735 57.7 52.8 517 189.2 108.84 3.9 0.615 92 0.478 12.05 7.98 0.135 55.5 14.6 0.73 22.3 68 0.166 7.39 4.46 1.55 117 15.4 9.9 185 36.7 31.93 1.3 0.119 8 0.074 0.33 0.49 0.092 17.5 4.2 0.02 11.6 18 0.059 0.34 0.33 0.28 678 66.7 40.1 465 209.0 136.72 6.2 0.813 94 0.410 12.06 7.83 0.070 57.9 13.8 0.76 21.0 67 0.169 7.66 4.62 1.55 210 41.7 7.9 169 38.5 36.92 1.2 0.145 12 0.078 0.43 0.65 0.071 14.5 3.2 0.02 7.3 14 0.040 0.38 0.35 0.26 571 59.5 37.5 451 229.9 167.28 7.7 0.811 99 0.196 11.09 6.91 0.041 46.8 12.2 0.74 14.8 56 0.135 7.65 4.32 1.30 137 18.2 6.2 145 43.6 35.33 1.3 0.143 14 0.050 0.44 0.69 0.041 12.0 2.8 5.7 12 0.047 0.39 0.22 0.12 3 n=9 5 n=9 7 n=9 10 n=9 LDHIU/L ASTIU/L ALTIU/L ALPIU/L LAPIU/L -GTIU/L UNmg/dL CREmg/dL GLUmg/dL TBmg/dL Camg/dL IPmg/dL UAmg/dL TCHOmg/dL FCHOmg/dL E/T TGLmg/dL PLmg/dL NEFAmEq/dL TPg/dL ALBg/dL A/G 839 48.4 68.9 600 129.2 92.67 6.5 0.450 107 0.305 11.83 8.74 3 98.2 22.5 0.77 36.1 136 0.170 6.01 4.01 2.04 143 10.1 12.8 164 15.7 23.98 1.0 0.060 22 0.128 0.51 0.74 5 14.9 3.8 13.9 18 0.042 0.25 0.14 0.35 905 65.0 54.6 583 135.3 124.94 11.4 0.714 84 0.426 12.61 9.14 0.104 98.5 22.9 0.77 33.0 125 0.215 7.17 4.57 1.77 237 30.4 8.0 182 29.2 32.39 3.1 0.083 10 0.080 0.41 0.87 0.084 9.2 2.3 12.0 8 0.058 0.41 0.28 0.21 857 67.7 56.6 486 130.9 148.72 11.6 0.852 64 0.410 12.38 10.07 0.188 98.6 23.9 0.76 38.9 115 0.207 8.25 4.87 1.45 141 29.1 12.4 220 34.8 50.41 2.3 0.100 11 0.055 0.30 1.02 0.079 11.5 3.0 18.1 6 0.030 0.51 0.30 0.18 711 51.6 43.9 413 120.4 143.80 11.8 0.909 77 0.212 11.73 6.73 0.091 81.3 21.1 0.74 40.9 109 0.163 8.19 4.66 1.34 87 9.7 7.3 266 21.2 58.24 2.2 0.101 9 0.038 0.36 0.69 0.050 14.4 3.4 0.02 20.2 14 0.026 0.54 0.13 0.17 日本 SPF 豚研究会 All About Swine, 35, 14-20 (2009)
n=5 n=5 CYPnmol/mg protein ERODVmax, nmol/mg/min TBHVmax, nmol/mg/min MDZHVmax, nmol/mg/min EROD 0 TBH MDZH 4 0.47 0.13 0.037 0.025 0.258 0.140 0.545 0.204 0.45 0.08 0.337 0.252 0.364 0.063 1.54 0.31 x10 2 counts/l 1 1 x10 4 counts/l 850 1,100 CYP -0- EROD -4- MDZH Vmax Table 8CYP Vmax 3 Galactose-1.3-galactose GALKODAF MCP Table 9 GALKO DAF MCP Table 9 Swine leukocyte antigensla SLA SLA SLA NIBS SLA All about SWINE No. 35 2009 18
Agene additionkogene knockout (Somatic cell nuclear transfer. Advances in experimental medicine and biology, Vol.591, 2007, Springer) Fig. 4 X MRI Fig. 5a c NIBS MRI WEB 19
All about SWINE No. 35 2009 20
日本 SPF 豚研究会 All About Swine, 36, 36 (2010) AAS 35 2009.9 Nutlization of a swine other than food Utilization of a swine other than food All about SWINE No. 36 2010 36