A () () () () - 1 -
A B C (PP)() B 11 (11p) (S-S) C ()C CPR CPR C peptide immunoreactivity C CPR () () B GLUT TCA ATP - 2 -
ATP K (VDCC) Ca () - 3 -
GLUT () K 80 () (GIF) GIFGastric inhibitory polypeptide B and/or - 4 -
()() A B B () () 10 1.5 HLA- () B ICA (islet cell antibody, ) IAA (insulin autoantibodies, ) GAD (glutamic acid decarboxylase) GADB () - 5 -
GLUT4 B B 9597 HLA - 6 -
170mg/dl (10 )126mg/dl ()200mg/dl 75gOGTT200mg/dl () OGTT(oral glucose tolerance test) 75g 3060 IRI(immunoreactive insulin) CPR CPR 1.03.5mg/mL 50120µg/ - 7 -
IRI () HOMA-R(homeostasis model assessment-r) (mg/dl)iri(u/ml)405 3.0 HbA C 12 4.35.8 1.5-AG - 8 -
- 9 -
- 10 -
- 11 -