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Feature Article Imaging of minuscule amounts of chemicals, Scannimg Chemical Microscope --- Increasing analysis information through imaging --- Abstract We have developed a Scanning Chemical Microscope for observing microscopic ph distribution. This microscope employs a two-dimensional ph sensor based on an electrochemical-semiconductor principle, which functions as an array of sensing parts. Each ph value is measured, converted, and then displayed as a ph image. Chemical imaging using this new microscope is expected to contribute to various fields of research. Some examples of imaging are introduced together with a set-up of the instrument. 22 No.18 March 1999

Technical Reports 23

a) b) 24 No.18 March 1999

Technical Reports a) 0 min 3 min 6 min 9 min 12 min 15 min 18 min 21 min ph ph=7.0 24 min 27 min 30 min 33 min 36 min 39 min 42 min ph=4.6 b) 0 min 3 min 6 min 9 min 12 min 15 min 18 min 21 min 24 min 27 min ph 9.0 2.4 30 min 33 min 36 min 39 min 42. min 45 min 48 min 51 min 54 min 57 min a) b) 10.3 5.5 25

a) b) c) a) b) 26 No.18 March 1999

Technical Reports 27