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再生医科学研究所年報 Annual Report of the Institute for Frontier Medical Sciences Kyoto University

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Institute for Frontier Medical Sciences 4 外科 内科治療アシストのための生体材料 本研究分野は 高分子 金属 セラミックス およびそれらの複合材料を医療に応用していくという 本研究所 の前身である生体医療工学研究センターの材料科学研究の流れを引いている その中で 生体内で吸収する性質を もつ高分子材料を中心として 外科 内科治療の補助のための生体材料の研究開発を行っている 上記の研究内容について 材料科学的な観点から 基礎および応用研究を行っている 得られた研究成果を基に 様々な生体組織 臓器 皮膚 骨 心臓冠動脈 脂肪 軟骨 神経 歯周組織 毛髪 心筋 腎臓など の再生誘 導のメカニズムの解明 その臨床応用 あるいは DDS 技術 方法論を用いた薬物治療 予防 診断などについて 医学部 歯学部 獣医学部 企業との共同研究を通した 応用研究を展開している 加えて 得られた材料や技術 の生物医学の基礎研究への応用についても共同研究を通して検討を進めている The main objective of our department is to investigate and develop methods, procedures, and technologies which are applicable to basic and clinical medicines as well as basic researches of biology and medicine from the viewpoint of material sciences. The materials to use in the body and to contact biological substances, like proteins and cells, are defined as biomedical materials and biomaterials. In our department, various types of biodegradable and non-biodegradable biomaterials of polymers, metals, ceramics, and their composites, are being designed and created aiming at their clinical applications as well as the development of experimental tools necessary for basic researches of medicine and biology which scientifically support clinical medicine. We are actively proceeding research and development R & D of biomaterials to assist reconstructive surgery and apply to drug delivery systems DDS for improved therapeutic efficacy. However, it is often difficult for patients to improve their Quality of Life QOL only by the therapeutic procedure of reconstructive surgery because the biomaterials applied are of poor biocompatibility and functional substitutability. For organ transplantation, 33 生体組織工学研究部門

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