PM2.5 2.5 µm PM2.5 1950 1979 CLRTAP 13 EANET2001 1972 SPM 10 µm µm PM2.5 PM2.5 SPM 1997 PM2.5 PM2.5 PM2.5 PM2.5 PM2.5 SPM PM2.5 PM2.5 PM2.5 PM2.5 PM2.5 PM2.5 PM2.5 15 2
Particulate Matter; PM 2.5 µm PM2.5 3
4 T Th T Th1 Th2Th1 IFN- IL-12 Th2IL-4 IL-13B IgE IgG1Th2 IL-5 Th1 Th2 Th2 PM2.5 Diesel Exhaust Particles; DEP DEP DEP Th2 IgE IgG1 DEP Th2 DEP DEP DEP [a] Benzo[a]pyrene; BaPBaP DEP Th1/Th2
BaP IgG1 BaP Th2 2010 BaP (A)-(C) Vehicle( ) (A) (OVA) ((B) ) BaP (C) (B) OVA ((C) OVA+BaP 20 (pmol/ / ) )) (D) OVAOVA+BaP 20 **; P<0.01, vs. Vehicle( ), #; P<0.05, vs. OVA 19 21 5
6 PM2.5 115 201 0.5 111 5
0.008 L/min2 Mei http:// www.nies.go.jp/risk/mei/mei002_12.html PM2.5 11 HEPA HO-1 20 nm 4 10 8 /cm 2 RT- PCR HO-1 PM2.5 7
PM2.5 1 1 PM2.5 PM2.5 PM2.5 PM Particulate Matter 2.5 2.5 µm mm 1000 PM2.5 2.5 µm 5 µm 2.5 µm 2.5 PM2.5 PM2.5 PM2.5 2.5 µm 2009 PM2.5 PM2.5 15 µg/m 3 35 µg/m 3 EU WHO PM2.5 600 24 1970 1200 PM2.5 PM2.5 EC PM2.5 21 PM2.5 http:// www.nies.go.jp/whatsnew/2013/20130221/ 20130221.html PM2.5 2013 36 PM2.5 24 169 8
PM2.5 PM2.5 35 µg/m 3 31 69.8 µg/m 3 36 16 35 µg/m 3 31 31.0 2011 2012 2013 4.0 2012 3.5 2011 1.0 PM2.5 PM2.5 PM2.5 PM2.5 70 µg/m 3 PM2.5 70 µg/m 3 PM2.5 PM2.5 PM2.5 10 PM2.5 1970 9
PJ3 G-CIEMS Grid-Catchment Integrated Environmental Modeling System; http://www.nies.go.jp/rcer_expoass/ gciems/gciems.htmlvol.30 No.5 FATE Finely-Advanced Transboundary Environmental model FATE persistent organic pollutants; POPs POPs POPs POPs PCBs DDT POPs 12 2004 24POPs POPs POPs BOX 10 FATE POPs FATE 5 POPs 2.520 1.0 50POPs - 10
FATE POPs FATE H25 ; http://www.cger.nies.go.jp/ja/activities/supporting/supercomputer/index.html POPs - - FATE FATE PCB153 0-200 m 2007 11
POPs 2008 FATE POPs POPs 2013 10 FATE 12
28 25 10 25 80 http://www.nies.go.jp/saigaikenkyu/saigaikenkyu_all.pdf 13
( ) 14
50, 25-27, 2013 20133150 Down-flow hanging sponge(dhs) Earozoru Kenkyu, 27(4), 350-356, 2012 30 3 SOA SOA SOA http://www.nies.go.jp/ kanko/kenkyu/setsumei/r-191-2006.html http://www.nies.go.jp/kanko/kenkyu/setsumei/r-205-2010.html 2000 In-situ growth rate of Microcystis spp. and their growth-limiting factors: use of cellular RNA content (Limnology, 12(3), 235-243, 2011) RNA(rRNA)(in-situ) rrna 15
1 20112012 10 2011 URL http://www.nies.go.jp/kanko/annual/ae19.pdf G-CIEMS 2001 GIS G-CIEMS URL http://www.nies.go.jp/kanko/kankyogi/50/02-03.html 35µg/m 3 PM2.5 30 PM2.5 31 GOSATCAI 201319 CAI M.Y. 305-8506 16 2 TEL 029-850-2343 E-mail pub@nies.go.jp http://www.nies.go.jp/kanko/news/