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1 3M TM Chlorhexidine Gluconate IV Securement Dressings Tegaderm TM CHG Support CRBSI Prevention

2 TegadermTM CHG Dressing 2w/w% 60% N. Safdar, Intensive Care Med

3 Guideline Centers for Disease Control and Prevention CDC Healthcare Infection Control Practice Advisory Committee HICPAC, Guideline for the Prevention of Intravascular Catheter-Related Infections 2011, , ,

4 7 days 5 10mm Mean Log Count log(10)cfu/cm M.H.BashirAmerican Journal of Infection Control Zone of Inhibition Beyond Gel Pad(MM) Days Debra L SchwabInfusion Nurses Society INS in Vitro test w/w% 0% 100% 200% Change

5 GRAM POSITIVE ZOI GRAM NEGATIVE & YEAST ZOI AVERAGE ZONE GEL DIAMETER 24 MM faecalis Wound Isolate #23 faecalis faecalis 7080 faecium(mdr)51559 faecium(vre) Corynebacterium diphtheriae aureus Nasal Isolate #849 aureus (MRSA)USA 800 aureus (MRSA)USA 500 aureus (MRSA)USA 600 epidermidis epidermidis epidermidis epidermidis epidermidis epidermidis(mrse) epidermidis(mrse) nasal isolate #492 aureus aureus (MRSA/GRSA)33592 aureus (MRSA)USA 100 aureus (MRSA)USA 300 AVERAGE ZONE Acinetobacter baumannii GEL DIAMETER MM Candida albicans Candida albicans Proteus mirabilis Proteus mirabilis Escherichia coli Klebsiella pneumoniae Klebsiella pneumoniae Enterobacter cloacae Acinetobacter baumannii BAA-747 Acinetobacter baumannii BAA-747 Pseudomonas aeruginosa Pseudomonas aeruginosa Pseudomonas aeruginosa Pseudomonas aeruginosa 9027 Pseudomonas aeruginosa J. P. Hensler Europian Congress of Clinical Microbiology and Infectious Diseases ECCMID Effective Against Most Common Pathogens Causing CRBSIs

6 1657R 1658R 1659R 1660R Please Recycle. Printed in Japan Copyright M. All Rights Reserved. HPM-442-F IT

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