GL_小川(聡)班_D.indd
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1 J-RHYTHM Pill-in-the-pocket Up-stream Circulation Journal Vol. 72, Suppl. IV,
2 Sicilian GambitSicilian Gambit CAST Sicilian Gambit Sicilian Gambit Sicilian Gambit Sicilian Gambit CD-ROM ACC/AHA/ESC Sicilian Gambit Sicilian Gambit 1random Na K Na K reentry vulnerable parameter Na K Na K 2 Na Na down regulation Na K K down regulation Sicilian Gambit J-RHYTHM J-RHYTHM 1640 Circulation Journal Vol. 72, Suppl. IV, 2008
3 Na Na-K Ca K If M2 A1 Fast Med Slow ATPase PR QRS JT A A A A I A A A A ATP Circulation Journal Vol. 72, Suppl. IV,
4 Sicilian Gambit Sicilian Gambit Sicilian Gambit Sicilian Gambit Marshal 1642 Circulation Journal Vol. 72, Suppl. IV, 2008
5 CaK renin-angiotensin systemras RAS K WPW PAI- focal mechanismmultiple wavelets random reentry Focal mechanism fibrillatory conduction focal mechanism Circulation Journal Vol. 72, Suppl. IV,
6 leading circle reentryanisotropic reentry spiral reentry AllessieAtrial fibrillation AFbegets AF CaCa down regulationna gap junction renin-angiotensin-aldosteroneraa 3 QOL 1644 Circulation Journal Vol. 72, Suppl. IV, 2008
7 . V f QOL QOL Maze Radial up-stream J-RHYTHM.. up-stream angio tensinreceptor Circulation Journal Vol. 72, Suppl. IV,
8 ARB ARB angiotensin converting enzymeace-i ACE-IARB NYHA Na ACE-IARB 1646 Circulation Journal Vol. 72, Suppl. IV, 2008
9 WPW RR msec Ca ARBACE-I up-stream ACE-IARB lone. PIAFAFFIRMRACESTAF QOL PIAFAFFIRMRACE STAF AFFIRM Circulation Journal Vol. 72, Suppl. IV,
10 AFFIRM J-RHYTHM J-RHYTHM J-RHYTHM, soft endpoint QOL. AFFIRM AFFIRM Na Na.. AFFIRM.. Ca.J-RHYTHM Sicilian Gambit. 4 CHADS /. QOL Circulation Journal Vol. 72, Suppl. IV, 2008
11 Circulation Journal Vol. 72, Suppl. IV,
12 QOL J-RHYTHM Na 16 INR.. TIA CHADS Congestive heart failurehypertensionage Diabetes MellitusStroke/TIA fractional shortening25 A 1-1.INR2.03.0A INR2.03.0A 2. 1INRINR1INRC a 1. 1 INR2.03.0A 2. INR2.03.0B INR C 4. A 5. 70INR C 6. C 7. C b mg 75mg C 2. C INR 75mgINR INR 3. 60C 4. INR2.03.0INR C 5. C 1. C 2. A 1650 Circulation Journal Vol. 72, Suppl. IV, 2008
13 INR Stroke/TIA CHADS 6 INR.. INR.INR. INR.. TIA 2 75 %FS25% 70 INR INR INR.. TIA 238 PT-INR.. ACUTE INR B APTT1.5 2 C INR C a C 2. TEE B 2-1. TEE APTT1.52 B 4 INR C 2-2. TEE 3 INR C 3. C b 3 a Circulation Journal Vol. 72, Suppl. IV,
14 a 1. INR B a 1. B 2. C 3. C C APTT APTT INR C 6. 7 C b 1. C K 4 INR a, 5 1. C 2. KC 3. C a 1. C 2. INR K C b 1. C 1652 Circulation Journal Vol. 72, Suppl. IV, 2008
15 a SPORTIF Xa a C C C C 1. C / / / J-RHYTHM AHA/ACC/ESC -Ca Na Lundstrom /mg/ /p.mg/ /p.ca Ca DAAF trial Circulation Journal Vol. 72, Suppl. IV,
16 Na J-RHYTHM Na WPW Na Ca KNa Ca Ca a7 Ca Na/K Na/KI 1654 Circulation Journal Vol. 72, Suppl. IV, 2008
17 Ca mg.mg/kg.mg/kgmg.mg mg WPWNa K 7 Na slow kinetic M 8 6 Na BrugadaST QOL Electrical Conversion / po 8 mgqt mg mg mgmg mg mg mg PV Isolation Ablate &Pace Ablate&Pace * 1 150mg 3 1mg/kg/10 300mg 3 1.4mg/kg/25 450mg 3 300mg 2R*3 1 2mg/kg/5 200mg 2 1 2mg/kg/10 *R:R Circulation Journal Vol. 72, Suppl. IV,
18 up-stream ACE-IARB Pill-in-the-pocket pill-in-the-pocket QT Brugada down-stream upstream upstream Ca AAT Ca PLC PKCMAPK AT Ca A Erk ACE-IARB up-stream ACE-IARB ARB ARB ACE-I 1656 Circulation Journal Vol. 72, Suppl. IV, 2008
19 meta-analysis ACE-I ARB ACE-I ARB ARB J-RHYTHM ARB Ca QOL up-stream CRP CRP ACE-IARB upstream CARTO complexed fractionated atrial electrogramcfae mm Circulation Journal Vol. 72, Suppl. IV,
20 c 1658 Circulation Journal Vol. 72, Suppl. IV, 2008
METs WPW QT LQTS 9Brugada 0 METs 30 Circulation Journal Vol. 67, Suppl. IV,
2002002 Guidelines for Exercise Eligibility at Schools, Work-Sites, and Sports in Patients with Heart Diseases (JCS 2003) JR 2 3 2 3 2 2 3 2 2 3 Circulation Journal Vol. 67, Suppl. IV, 2003 309 2002002
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J Arrhythmia Vol 23 (Suppl) 2007 PD-I-1 OACIS 95% 6.4 (1.5 27.8 4.3 (1.0 18.5), 0.2 (0.05 0.93), respectively MADIT LVEF 30% 192 2.0 12.4% 24 3.1% MADIT 12.1% p=.001), ICD direct PCI OACIS (Osaka Acute
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QT QT QT QT Brugada Brugada Brugada Brugada Brugada Brugada QT QTQTc Torsade de pointes T-wave alternans Notched T wave in leads Circulation Journal Vol. 71, Suppl. IV, 2007 1257 TdP QT Na + ICD QT QT
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