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8 Imamura, C Imamura, 2008 TRPM8 Chen, 2009; Zhang, 2012Chen, 2009 Noguchi, 2013) Yamagishi, TRPM8 C Imamura, 2013 Zhang,2006; Imamura, 2008 ATP Imamura, 2009 C C Imamura, 2013

9 BNP /24 / / BNP 20pg/ml 36 G7.5g/ 3 / F20mg / 1G F AFG B BNP Wilcoxon A 21 B 15 1I-PSS F G 2.3 vs 2.9, p=0.032; 3.0 vs 3.3, p= I-PSS PSQI 3 F G 7.2 vs 6.4, p=0.022; 1103mL vs 975mL, p= F G 3.3 vs 3.9, p<0.001; 793mL vs 897mL, p<0.0015hus F vs G, 0.37 vs 0.47, p<0.001; 168 vs 135, p= BNP neural cross-talk Neural cross-talk nonneural cross-talk cross-talk Cross-talk

10 1TUR-P 2 1TUR-P 142 TUR-P 3.0gr gr p=0.043, Chi-square test, Odds ; %CI; TUR-P LUTS QOL

11 74 2 CT IVP cc 22 PSA IPSS cm 66kg

12 80 JCHO g Gy/35 /7 1 66Gy/33 /6.5 IPSS QOLOABSS Gy/9 42Gy/21 24Gy/ IPSS QOL OABSS g/ IPSSQOL 1 30 IPSS IPSS-QOLBII scoreufm 8-OHdG hanp.ipssipss-qolbii scorenpi 1

13 NO NO Kito Y, Teramoto N. Effect of HangeshashintoTJ-14and Keishi-ka-shakuyaku-toTJ-60on contractile activity of circular smooth muscle of the rat distal colon. Am J Physiol Gastrointest Liver Physiol. 303: G g OABSS ml 1 QOL QOL ml42cmH2O ml 550ml 110cmH2O

14 CPPS CPPS POP-Q stage1 2 CPPS Visual analogue scalevas CPPS OABSS VAS P=0.018 OABSS P=0.173 OABSS CPPS mg 1 20mg g mg 50g 1 40mg 4

15 R CPDX-PR ; CPDX-PR100mg 2 1 A 2; 1 2.5gr. x 3 x4 B 3; 1 2.5gr. x 3 x4 C VAS0-10 [ ] 1 WBC<5-10/hpf E.coli77 E.coli5 LVFX K.pneumoniae6 P.mirabilis, S.marcescens 1 CPDX-PR ANOVA 1 21/3070.0%, 18/ %, 23/3076.7%A,B,C 4 23/3076.7%, 22/3073.3%, 28/3093.3%8 22/3073.3%, 23/3076.7%, 26/3086.7% 1 22/3073.3%,24/3080.0%, 27/3090.0%4 25/3083.3%, 26/3086.7%, 28/3093.3%8 23/3076.7%, 24/3080.0%, 27/3090.0% C 8

16 Gold standard A B ) retrospective g 5 2 retrospective % % % 1 retrospective : 89-92, 2013.

17 69 20 H H mg4T1x 330mg3T OHDF 4 ABH 21P PQB250ml/m QD500ml/m 40L NaKt/V1.29 ESA T 0.25 g OD30 O200 H H kg 40 5 H H ED 90 ED IMRTLDRHDR ED 75 PDE ED IIEF IIEF IIEF IIEF IIEF IIEF5 PSA ED

18 LOH PDE PDE CT CT 4 CT 6 12 IgA 3 3

19

200 30 984 1 1854 1713 1000 1008 ED ADL/QOL The European Working Group on Sarcopenia in Older People EWGSOP Asian Working Group for Sarcopenia AWGS D C Zhang, 2006 C Imamura, 2008 ATP Imamura, 2009 Imamura,

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4 100g 100g 10 20 30 40 50 60 70 80 4 5 7 9 12 15 19 24 60 100 10 80 100 20 10 5 20 195 20-1- 60 60 15 100 60 100 15 15 15 100 15 15 60 100 10 60 100 100 15 10 10 60 100 15 10 15 10 5-2- 80 80 24 100 80 100 24

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