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1 3 / 70 4 / 70 SAS Enterprise Guide (SAS / SAS Enterprise Guide ) Kengo NAGASHIMA Laboratory of Biostatistics, Department of Parmaceutical Technochemistry, Josai University / 70 2 / 70 SAS SAS (Statistical Analysis System), 100, 45,000,, SAS, SAS

2 7 / 70 8 / 70 SAS Enterprise Guide, Windows SAS, SAS,,,, SAS SAS Enterprise Guide SAS: SAS Enterprise Guide:, SAS SAS Enterprise Guide... 5 / 70 6 / 70 SAS Enterprise Guide PC SAS Enterprise Guide 4.2 SAS Enterprise Guide

3 11 / / 70,,, : :, : :, :, :,, 9 / / 70 [ ],

4 15 / / 70 ( tamo.xls (Excel ) ) SAS 13 / 70 :,, 14 / 70,

5 19 / / 70,,, Excel 17 / 70 (.xls) 18 / 70 Excel, SAS ( )

6 23 / / ,, % % 3.5% ( ) 368/1215=30.3%, 253/760=33.3% -3.0% ( ) 464/2549=7.2%, 424/2352=10.7% -3.5% 464/2549=18.2%, 424/2352=18.0% 21 / 70,,, (1) [ ] [ ] [ ] [ ] [ ] ( & ) 22 / 70

7 27 / / 70 (2) [ ], [ ] OK [ ], [ ] [ ] 464/2549=18.2%, 424/2352=18.0% 25 / 70 [ 1] [ 1 ] ] [ ] [ ] [χ 2 ] [ ] [ ] 26 / 70, (α = 0.05 ) H 0 : H 1 : P-value=0.873, α = 0.05

8 31 / / 70 [ 1] [ 1 ] [ ] [ ] [ ] [2 2 ] [ ] [ ] =0.0018, 95% 0, 29 / 70,,, (1) 30 / 70 [ ] [ ], [ ] ( & ) [ ]

9 35 / / 70 (2) [ ], [ ] [ ], [ ] [ ] 368/1215=30.3%, 253/760=33.3% 96/1334=7.2%, 171/1592=10.7% (1) [ ] [ ] [ ] 33 / 70 [ ], [ ] [ ] ( & ) [ ] [ ] (2) 34 / 70 [ ] [ ], [ ] [ ] [ ] [ ] [Wald ] [ ]

10 39 / / 70 (1) logit(p ) =β + β x 1+ β x 2 (2) 0.25, P-value=0.0017, α = , 95% [0.669, 0.912], 37 / / 70 2,,,,, (, ), ( ) [ ] [ ] [ ],,,

11 43 / / [4] [5] [ ] (1) [ ] [ ] [ ] [ ], 10,, 2, [byouin.xls] 1 41 / / 70 (2) [ 10 ] [ ], [ ] [ ] & [ ] [ ], [ ], [ ] [ ] (3) [ ],

12 47 / / : 6.3, 1.75 : 10.1, : 50.4, 8.79 : 45.6, : 74.9, 12.9 : 81.7, , 10, 45 / / 70 t (1) [ ] [ ] [t ] [2 t ] [ ] 10 10, 10,

13 t (2) [ 10, (Log)] [ ], [ ] [ ] & [ ] [ ] [ Q Q ] [ ] t ( 10 (Log)) H 0 :, 10 (Log) H 1 :, 10 (Log) t ( 10 ) 49 / 70 P-value<0.0001,,, 10 (Log) 50 / 70 t ( 10 ) H 0 :, 10 H 1 :, 10 Q Q, 51 / 70 P-value=0.06,,, / 70

14 (1) [ ] [ ] [ ] [ 10 ] [ ], [ ] [ ] & [ ] (2) [ ] [Wilcoxon] [ ] 53 / 70 H 0 :, 10 H 1 :, 10 [1] Der G, Everitt BS. Basic statistics using SAS Enterprise Guide : a primer. SAS Publishing, / 70 [2] ( ), SAS Institute Japan ( ). SAS SAS Enterprise Guide., [3] [4]. 19 ( ) [5] P-value=0.04,,, / / 70

15 59 / / 70, [ ] [ ] :, 57 / / 70 [ ] [ ] [ ] [ ] [RTF] RTF, Word &

16 63 / / 70 [ ] [ ] [RTF] [ ] ( ) : sas/odsstyle/ods_style.html BarrettsBlue Listing Journal 61 / / 70 (1) [ ] [ ] [ ] (2) [ ] [ ] [OK]

17 67 / / 70 SAS [ ] [ ] [ ] Mantel Haenszel,, [ 2] [ 2 ] [ ] [ ] [CMH ] [ ] [ ] SAS SAS 65 / / 70, Mantel Haenszel (α = 0.05 ) H 0 :, H 1 :, (1) [ ] [ ] [ ] [WORK] [ ] P-value=0.0009, α = 0.05

18 (2), [x] [y] [n] [ ], (3) [ ] [ ] [ ] [x] [y] [n] [ ] 3 69 / / 70

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