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- さあしゃ あみおか
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1 (DDS)( ) DDS Drug Delivery System (pulmonary drug-delivery) Aradigm AERx AERx 3 3 Novo Nordisk NEDO AERx
2 1 Aradigm AERx (a) (b) (Aradigm Web ) (a) (b) Nektar 4 (Exubera) Nektar (inhaled amikacin) Alkermes 5 AIR Alkermes AIR Aerogen 6 SC GE 3M 7 6, M (3M Web ) 4 Nektar 5 Alkermes 6 Aerogen 7 3M iontech/ 2
3 Alexza Pharmaceuticals 8 Staccato ,000 (agitation) (Staccato loxapine) 3 Next Safety (2) (surface modification) Abbott ABSORB 13 Abbott Lancet ABSORB 3 Abbot ABSORB (Abbot Web ) REVA Medical Alexza Pharmaceuticals 9 Next Safety DES (Drug eluting stent) 13 Abbott ABSORB Press_Release_0588.htm 14 REVA Medical 3
4 15 MIV Therapeutics (3) (Ophthalmic delivery) InSite Vision 18 DuraSite AzaSite AzaSiteDuraSite (blepharoconjunctivitis) AzaSite Plus InSite Vision AzaSite ( ) (Insite Vision Web ) MIV Therapeutics 17 (bioavailability) 18 InSite Vision 4
5 Novagali Pharma 19 Novasorb Eyeject Nova63035 FDA IND 20 (4) (Iontophoresis) 21 Vyteris 22 Vyteris Smart Patch Smart Patch 5 vyteris LidoSite ( ) ( ) LidoSite (vyteris Web ) Alza 23 E-TRANS Transdermal 3 IOMed Novagali Pharma 20 IND (investigational new drug) INDA Investigational New Drug Application IND FDA Vyteris 23 Alza 24 IOMed 5
6 Hybresis 25 Ocuphor (5) Abraxis Bioscience FDA ABRAXANE ABRAXANE 27 (mucus layer) Elan Drug Technologies nm 6cm 2 12cm 2 24cm 2 6 (GRAS:Generally Regarded As Safe) (Elan Drug Technologies Web ) Abraxis Bioscience Elan Drug Technologies 6
7 Elan (NanoCrystal) Paliperidone Palmitate (NDA) FDA 4 29 NEC (6) (open a door) NEDO No
8 (7) Osel ) 2) MucoCept Osel 2 3 CDACTIN-O CDACTIN-O MIYA-BM Osel Biophage Pharma 35 Biophage Pharma (8) (Gene therapy vectors) 36 Calando Pharmaceuticals RNAi RNAi FDA (IND) sirna 33 Osel 34 (microflora) 35 Biophage Pharma =12&Itemid=
9 Neurologix FDA 2 Oxford BioMedica 38 LentiVector Oxford BioMedica TroVax 3 T 5T4 MVA 5T4 7 TroVax TroVax 5T4 5T4 T TroVax 5T4 MVA T 5T4 (Oxford BioMedica Web ) 37 Neurologix 38 Oxford BioMedica 9
10 Benda Pharmaceutical 39 Ebei GMP 40 Ebei Gendicine p53 (9) (nanoencapsulation) 41 (flash nanoprecipitation) (NIST) NISTI 2008 (microfluidics) Benda Pharmaceutical GMP: Good Manufacturing Practice Microfluidics cm 44 Point of care (POC) 10
11 (SRI Consulting Business Intelligence Explorer Program) NEDO 11
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ISSN 1348-5350 2008.7.2 BIWEEKLY 1025 NEDO 海外レポート 212-8554 神奈川県川崎市幸区大宮町 1310 ミューザ川崎セントラルタワー http://www.nedo.go.jp Ⅰ. テーマ特集 - ライフサイエンス バイオテクノロジー - 1. 薬剤送達システム (DDS) の開発 商品化状況 ( 世界 ) 1 2. パーソナライズドメディスン (
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