J-RHYTHM Pill-in-the-pocket Up-stream Circulation Journal Vol. 72, Suppl. IV, 2008 1639
Sicilian GambitSicilian Gambit CAST Sicilian Gambit Sicilian Gambit Sicilian Gambit Sicilian Gambit CD-ROM ACC/AHA/ESC Sicilian Gambit Sicilian Gambit 1random Na K Na K reentry vulnerable parameter Na K Na K 2 Na Na down regulation Na K K down regulation Sicilian Gambit J-RHYTHM J-RHYTHM 1640 Circulation Journal Vol. 72, Suppl. IV, 2008
Na Na-K Ca K If M2 A1 Fast Med Slow ATPase PR QRS JT A A A A I A A A A ATP Circulation Journal Vol. 72, Suppl. IV, 2008 1641
Sicilian Gambit Sicilian Gambit Sicilian Gambit Sicilian Gambit Marshal 1642 Circulation Journal Vol. 72, Suppl. IV, 2008
CaK renin-angiotensin systemras RAS K WPW PAI- focal mechanismmultiple wavelets random reentry Focal mechanism fibrillatory conduction focal mechanism Circulation Journal Vol. 72, Suppl. IV, 2008 1643
leading circle reentryanisotropic reentry spiral reentry AllessieAtrial fibrillation AFbegets AF CaCa down regulationna gap junction renin-angiotensin-aldosteroneraa 3 QOL 1644 Circulation Journal Vol. 72, Suppl. IV, 2008
. V f QOL QOL Maze Radial up-stream J-RHYTHM.. up-stream angio tensinreceptor Circulation Journal Vol. 72, Suppl. IV, 2008 1645
ARB ARB angiotensin converting enzymeace-i ACE-IARB NYHA Na ACE-IARB 1646 Circulation Journal Vol. 72, Suppl. IV, 2008
WPW RR msec Ca ARBACE-I up-stream ACE-IARB lone. PIAFAFFIRMRACESTAF QOL PIAFAFFIRMRACE STAF AFFIRM Circulation Journal Vol. 72, Suppl. IV, 2008 1647
AFFIRM J-RHYTHM J-RHYTHM J-RHYTHM, soft endpoint QOL. AFFIRM AFFIRM Na Na.. AFFIRM.. Ca.J-RHYTHM Sicilian Gambit. 4 CHADS /. QOL 5 1648 Circulation Journal Vol. 72, Suppl. IV, 2008
Circulation Journal Vol. 72, Suppl. IV, 2008 1649
QOL J-RHYTHM Na 16 INR.. TIA CHADS Congestive heart failurehypertensionage Diabetes MellitusStroke/TIA 1. 7535fractional shortening25 A 1-1.INR2.03.0A 1-2.2 INR2.03.0A 2. 1INRINR1INRC a 1. 1 INR2.03.0A 2. INR2.03.0B 3. 6574 INR2.03.0 C 4. A 5. 70INR1.62.6 C 6. C 7. C b 1. 100mg 75mg C 2. C INR 75mgINR2.03.0 INR 3. 60C 4. INR2.03.0INR2.53.5 C 5. C 1. C 2. A 1650 Circulation Journal Vol. 72, Suppl. IV, 2008
INR2.0 3.0 Stroke/TIA CHADS 6 INR.. INR.INR. INR.. TIA 2 75 %FS25% 70 INR2.0 3.0 70 INR1.6 2.6 1 2 6574 INR.. TIA 238 PT-INR.. ACUTE 1. 48 3 4 INR2.03.070 1.62.6B 2. 48 APTT1.5 2 C INR2.0 3.0701.62.64 3. 48 C a 1. 48 C 2. TEE B 2-1. TEE APTT1.52 B 4 INR2.0 3.070 1.6 2.6C 2-2. TEE 3 INR2.03.0 701.62.6 4 C 3. C b 3 a Circulation Journal Vol. 72, Suppl. IV, 2008 1651
a 1. INR B a 1. B 2. C 3. C 4. 35 C APTT1.52.5 46 APTT INR 5. 1014 314 C 6. 7 C b 1. C K 4 INR a, 5 1. C 2. KC 3. C a 1. C 2. INR K C b 1. C 1652 Circulation Journal Vol. 72, Suppl. IV, 2008
a SPORTIF Xa a 1. 13 C 2. 1433 C 3. 3436 C 4. 3436 C 1. C / / / J-RHYTHM AHA/ACC/ESC -Ca Na Lundstrom /mg/ /p.mg/ /p.ca Ca DAAF trial Circulation Journal Vol. 72, Suppl. IV, 2008 1653
Na J-RHYTHM Na WPW Na Ca KNa Ca Ca a7 Ca Na/K Na/KI 1654 Circulation Journal Vol. 72, Suppl. IV, 2008
Ca mg.mg/kg.mg/kgmg.mg mg WPWNa K 7 Na slow kinetic M 8 6 Na BrugadaST QOL Electrical Conversion / po 8 mgqt mg mg mgmg mg mg mg PV Isolation Ablate &Pace Ablate&Pace * 1 150mg 3 1mg/kg/10 300mg 3 1.4mg/kg/25 450mg 3 300mg 2R*3 1 2mg/kg/5 200mg 2 1 2mg/kg/10 *R:R Circulation Journal Vol. 72, Suppl. IV, 2008 1655
up-stream ACE-IARB Pill-in-the-pocket pill-in-the-pocket QT Brugada down-stream upstream upstream Ca AAT Ca PLC PKCMAPK AT Ca A Erk ACE-IARB up-stream ACE-IARB ARB ARB ACE-I 1656 Circulation Journal Vol. 72, Suppl. IV, 2008
meta-analysis ACE-I ARB ACE-I ARB ARB J-RHYTHM ARB Ca QOL up-stream CRP CRP ACE-IARB upstream CARTO complexed fractionated atrial electrogramcfae mm Circulation Journal Vol. 72, Suppl. IV, 2008 1657
c 1658 Circulation Journal Vol. 72, Suppl. IV, 2008