Title Author(s) 日本における受精卵診断をめぐる論争 (1990 年代 ) - 争いの経過 - 利光, 恵子 Citation 医療 生命と倫理 社会. 7 P.67-P.85 Issue Date 2008-03-20 Text Version publisher URL https://doi.org/10.18910/12560 DOI 10.18910/12560 rights
1990 preimplantation genetic diagnosis: PGD 1 1990 1998 2 1999 2004 7 1 3 2004 (2008 1 ) 2005 2005 2006 2 12 67
1990 1 2 1970 1997 1998 2000 2001 2001 1996 2006 1 1990 2008 1989 2 1991 Gary 1991 1992 4 22 1993 7 8 X 3 1996 2000:53-84 1995 3 9 X 3 3 24 1995.3.10 1995.3.10 68
4 3 24 1999 1995 9 11 2000:549 12 1995.9.12 1995.9.12 1995.10.25 10 23 19 1995.10.24 X 3 11 12 1995.12.15 1994 10 1993 69
5 1996 5 31 9 1996.6.1 1997 2 5 22 1997.2.11 2 18 26 34 1 2 3 4 4 1997.2.19 2 19 52 2 22 70
1997.2.23 1997.3.15 1997 5 6 3 3 12 8 4 1998 2 SOSHIREN 3 3 14 1 3 31 1997 5 4 1998.4.1 1998 4 10 1998.4.10 60 4 18 5 9 6 10 2 1997 7 24 13 2 71
66 10 2 1998 6 27 1998.6.28 98.6.28 9 10 7 25 34 8 1998.9.20 1998.7.261998.8.7 98.8.5 12 12 9 1999 1 28 2000 1999.1.29 1999.1.29 2 17 74 1999 2 17 10 1999 5 24 2000 2 26 2000 1999 5 11 72
11 6 19 1999.6.20 2000 5 29 2000 9 11 2000.9.14 2003 1 2002b:203 2002a:538 2003 9 9 2004 1 5 2004 2 2004 7 1 73
2004 7 23 1990 1990 1997:3 1994:15 1997:3 1-6 2004 7 74
2008 970 1995 3 19951998 4 2006:78 1 2 3 4 1997 2 18 1 3 1 2 75
1997.2.19 12 1997 2 52 1997 2 19 1999 1 74 1999 2 17 1 1998 3 14 1998:427 1-6 1999 2000 76
1 2007:649 2006:178 1989 Handyside 1989 X Handyside et al 1990 Handyside et al 1992 Munne 19931999 FISH 13 ESHRE PGD Consortium Steering Committee 1999; Verlinsky et al 2004 14 3000 Sermon et al 2007 15 1991 1993 2004 2 1997 2 98 4 1998 7 2006 2 16 77
17 4 17 ESHER PGD Consortium X ESHER PGD Consortium 1999 18 19 policy making 1999:16 1989:43-50 2006:174-178 1990 1990 2004 7 23 2005 78
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1 19962004 19961998 2004 200320052006 1994 1999 2004 2006 2005 20002001a2001b 2002 5 2006 1996 1997 1998 19981999 1999 2001 2002 2005 2 Jones Institute 1991:352 3 X X X 1 X 4 1995.3.25 4 5 5 95 97 2 97 3 99 4 99 5 2000 7 2000 8 6 1998.5.31 7 98 6 24 1998:39-49 8 SOSHIREN DPI DNA 83
9 8 98.12.12 1999.1.19 10 11 FISH 12 2 1998 6 10 1998:925 13 FISHfluorescence in situ hybridization DNA DNA 14 Munne PGD preimplantation genetic screening PGS PGD for aneuploidy screening PGDAS) International Working Group for Preimplantation Genetics 1997 377 X 4 3 3 1998:63-68ESHRE PGD Consortium 1997 1 1998 9 392 X 1998 PGS 3 15 p53verlinsky et al 2001a Rechitsky et al 2002 Verlinsky et al 2002 Verlinsky et al 2001b 2006:154 84
16 http://www.jsog.or.jp/about_us/view/html/kaikoku/h18_7_chakushouzen-kenkai.html 17 17 4 http://www.jsog.or.jp/about_us/minutes/pdf/gijiroku/h17_04riji.pdf 18 ESHER PGD Consortium 1997 1 1998 9 392 29 PCR 4 ESHER PGD Consortium 1999 19 1990 1997 7 98 10 99 5 2005 1990 85