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Transcription:

Post-Polio Syndrome; PPS 2008 2 23

PoliomyelitisPolio PPS

18 BC1580 BC1350 30nm

Iron Lung 1930 1916 27,363 7,179 26.2% Rancho Los Amigos National Rehabilitation Center

Incidence Rates of Poliomyelitis in Japan Compliled by Polio Association (President Mariko Koyama: koyama@mrg.biglobe.ne.jp) Sources: White Papers from Ministry of Health and Welfare, and et al. A. Kawakita, Infantile paralysis (1961), Iwanami Paperback Edition Year No. of Patients Disease Rate* No. of Deceased Mortality Rate* Fatality Rate 1947 275 (3) -- 1,009 -- -- 1948 993 1.2 775 1 78.0 1949 3,127 3.8 1,074 1.3 34.3 1950 3,212 3.9 775 0.9 24.1 1951 4,233 5.0 570 0.7 13.5 1952 2,317 2.7 508 0.6 21.9 1953 2,286 2.6 441 0.5 19.3 1954 1,921 2.2 442 0.5 23.0 1955 1,314 1.5 314 0.4 23.9 1956 1,498 1.7 290 0.3 19.4 1957 1,718 1.9 255 0.3 14.8 1958 (1) 2,610 2.8 243 0.3 9.3 1959 2,917 3.1 201 0.2 6.9 1960 5,606 6.0 319 0.3 5.7 1961 (2) 2,436 2.6 188 0.2 7.7 1962 289 0.3 58 0.1 20.1 1963 139 0.1 27 0.05 19.4 1964 84 0.06 24 0.03 28.6 1965 76 0.05 28 0.05 36.8 1966 33 0.02 17 0.02 39.4 1967 26 0.02 16 0.02 15.4 1968 20 0.01 13 0.01 65.0 1969 16 0.01 12 0.01 75.0 1970 8 0.0 11 0.01 -- Sub-total 37154 7,610 1971 6 0.0 8 0.01 -- 1972 7 0.0 1 0.0 14.3 1973 6 0.0 4 0.0 66.7 1974 4 0.0 2 0.0 50.0 1975 4 0.0 3 0.0 75.0 Polio Survivors 1916 27,363 7,179 26.2 1961 *Disease Rate & *Mortality rate: 1/100,000 (1) Administration of Salk vaccine was started (2) Urgent administration of Sabin vaccine Rancho Los Amigos National Rehabilitation Center (3) Official poliosurveillance first started from September 1, 1947 (4) Last patients from the wild-type virus in Japan

Incidence Rates of Poliomyelitis in Japan Compliled by Polio Association (President Mariko Koyama: koyama@mrg.biglobe.ne.jp) Sources: White Papers from Ministry of Health and Welfare, and et al. A. Kawakita, Infantile paralysis (1961), Iwanami Paperback Edition Year No. of Patients Disease Rate* No. of Deceased Mortality Rate* Fatality Rate 1971 6 0.0 8 0.01 -- 1972 7 0.0 1 0.0 14.3 1973 6 0.0 4 0.0 66.7 1974 4 0.0 2 0.0 50.0 1975 4 0.0 3 0.0 75.0 1976 0 0 0 0 0 1977 0 0 0 0 0 1978 0 0 0 0 0 1979 0 0 0 0 0 1980 2 (4) 0.0 0 0 0 1981 2 0.0 0 0 0 1982 1 0.0 0 0 0 1983 0 0 0 0 0 1984 0 0 0 0 0 1985 1 0.0 0 0 0 1986 0 0 0 0 0 1987 2 0.0 0 0 0 1988 0 0 0 0 0 1989 0 0 0 0 0 1990 0 0 0 0 0 1991 0 0 0 0 0 1992 0 0 0 0 0 1993 3 0.0 0 0 0 1994 1 0.0 0 0 0 1995 1 0.0 0 0 0 1996 0 0 0 0 0 1997 0 0 0 0 0 1998 0 0 0 0 0 Total 37,194 7,628 *Disease Rate & *Mortality rate: 1/100,000 1916 27,363 7,179 26.2 (1) Administration of Salk vaccine was started (2) Urgent administration of Sabin vaccine (3) Official poliosurveillance first started from September 1, 1947 Rancho Los Amigos National Rehabilitation Center (4) Last patients from the wild-type virus in Japan

Incidence Rates of Poliomyelitis in Japan Compliled by Polio Association (President Mariko Koyama: koyama@mrg.biglobe.ne.jp) Sources: White Papers from Ministry of Health and Welfare, and et al. A. Kawakita, Infantile paralysis (1961), Iwanami Paperback Edition 1916 27,363 7,179 26.2 Rancho Los Amigos National Rehabilitation Center

1927-1931 Jonas Salk 1952 Albert Sabin 1957 1961 1916 27,363 7,179 26.2 March of Dimes) 1961 Rancho Los Amigos National Rehabilitation Center

1 1960,,,. 1960 12 20 1916 27,363 7,179 26.2 1,641, 106 1960 1 5,606 Rancho Los Amigos National Rehabilitation Center

2 1960 2003 8 1916 27,363 http://www.geocities.jp/hokukaido/mother/index.htm 7,179 26.2 Rancho Los Amigos National Rehabilitation Center

( 1961 6 7 8 1 1,000 35 9

3 1961 1961 2,436 1962 1963 1916 27,363 7,179 26.2 70 1980 2 Rancho Los Amigos National Rehabilitation Center

PPS 1916 27,363 7,179 26.2 Rancho Los Amigos National Rehabilitation Center L. Halstead National Rehabilitation Hospital, Halstead L.S.

1916 27,363 7,179 26.2 Rancho Los Amigos National Rehabilitation Center

PPS USA 250,000 Germany 40,000 Japan 40,000 France 25,000 Australia 16,000 Canada 12,000 UK 12,000 1 ~2 4 8 PPS Source: WHO & March of Dimes (2005)

1916 27,363 7,179 26.2 Rapid-fatigue Unaccustomed fatigue( ) Rapid-fatigue Unaccustomed fatigue Rancho Los Amigos National Rehabilitation Center

PPS 86-87 71-86 71-79 69-87 50-77 29-56 28-39 64-85 61-83 16-62 1916 27,363 7,179 26.2 Rancho Los Amigos National Rehabilitation Center Lauro S. Halstead Managing Post-Polio

1991 1984 4 1988 4 1916 27,363 7,179 26.2 1991 6 1985-1991 242 3012 50 5 40 Rancho Los Amigos National Rehabilitation Center ALS

S 1765 9 18 44 1989 1995-2003 Rapid-fatigue PPS MRI 6 EMG NCS PPS,

OSCEOSCE 1 17 18 OSCE Objective Structured Clinical Examination OSCE 1975 OSCE

2 2007 6

3 2008 1 27 1 2 OSCE

2008 1 47 A4 100 3 1-6-5-602 1,300 550

Lauro S.Halstead, M. D. A4 227 B5 122

2008 2 12 WHO ()

1 PPS or MRI 1 PPS PPS PPS PPS

2 PPS PPS 1 1 / -

3 PPS PPS NHK PPS A.

4 PPS PPS PPS PPS

5 100 1 PPS 3

1 1995 12 PPS 2000 2004

2 PPS 34 30008 4 700013 5 5000 101 2000 PPS

3 PPS PPS PPS PPS

4 1,300 550 3 OSCE A4

(1) 2001/07 2001/10 2002/01 2002/04 2002/01 2003/01 2003/04 2003/04 2003/08 2003/11 2004/02 2004/08 2004/11 2005/02

(2) 2005/05 2005/08 TEKES 2005/12 2006/03 2006/04 2006/07 2006/11 2007/03 AKA 2007/07 PPS) 2007/10

1 2007 2006 AKA

2

3 Jacquelin Perry, MD, DSc (Hon) Medical Consultant, Post- Polio Service, Rancho Los Amigos National Rehabilitation Center 2001 Kirsten Götz-Neumann Perry Gunnar Grimby, M.D., professor emeritus and former head of the Department of Rehabilitation Medicine at Sahlgrenska University Hospital in Göteborg, Sweden 2004 PPS

4 HAL HAL

5 44,,

Dr. R. Bruno

Dr. J. Silver Dr. L. Halstead

J. K.