肺癌第42巻第6号

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1 REPORT n n5 5 6 c-stage 5 c-stage IAn687.5c-STAGE IBn665c-STAGE IIAn69 7.8c-STAGE IIBn793c-STAGE IIIAn3853.6c-STAGE IIIBn c-STAGE IVn69.9 p-stage 5 p-stage IAn79.p-STAGE IBn88 6p-STAGE IIAn658.6p-STAGE IIBn785.p-STAGE IIIAn337 8.p-STAGE IIIBn759p-STAGE IVn ;: Lung Cancer in Japan : Analysis of Lung Cancer Registry for Resected Cases in 99 Japanese Joint Committee of Lung Cancer Registry Takayuki Shirakusa President, The Japan Lung Cancer Society Koichi Kobayashi President, The Japanese Association for Chest Surgery Summary Lung cancer cases78 casesthat were surgically resected during 99 were registered and collected for analysis. The survival rate for the total cases was 5.9. The 5-year survival rate was 8. in malen59and 6 in femalen5. The 5-year survival rates by c-stage were: c-stage IAn68, 7.5;c-STAGEIBn66, 5 ; c-stage IIAn69, 7.8; c-stage IIBn793, ; c-stage IIIAn385, 3.6; c-stage IIIBn 395, 7.6;c-STAGEIVn6, 9.9. The 5-year survival rate by p-stage was: p-stage IAn, 79.; p-stage IBn88, 6; p-stage IIAn6, 58.6; p-stage IIBn785,.; p-stage IIIAn337, 8.; p-stage IIIBn759, ;p-stageivn75, 9.3. Of the surgically resected cases, the most frequent histological type was adenocarcinoma at 55.7; next, squamous cell carcinoma, 33., large cell carcinoma 3.6, and small cell carcinoma 3.. Operative death amounted to cases., hospital deaths to cases.7.operationhospital death mortality rate in surgically resected cases was 3..JJLC. ;: Reprints: Tomoyuki Goya, Japanese Joint Committee of Lung Cancer Registry, Department of Surgery, School of Medicine, Kyorin University, 6-- Shinkawa, Mitaka, Tokyo 8-86, Japan. The Japan Lung Cancer Society Japanese Journal of Lung CancerVol, No 6, Oct, 555

2 ctnm ptnm TNM 997 TNM Table.Age distribution Year old Default Total Cases A total of cases were entered in this registry, and classified according to age distribution TNM cTNMT 9cTNMN ctnmm c-stage cm d3pm 5 ptnmt 6pTNMN 7pTNMM 8p-STAGE 9 33a3p UICC-TNM Table.Survival rates for 738 cases Year Survival rate Y 8. Y 7.3 It was possible to calculate survival time in 788 cases, and of these, prognosis articles of not available amounted to 5 cases. In the remaining 738 cases, survival analysis was performed. Calculation of the survival time was set from the operation date to the final confirmed surviving date. Deaths in the prognosis article were designated as death cases in the calculation of the survival curve, whereas survivors and unknown cases were designated as censored cases. 3Y 6.3 Y 56. 5Y Japanese Journal of Lung CancerVol, No 6, Oct,

3 Kaplan-Meier Figure Survival rates for 738 cases survival probability years Excel SPSS ver SAS version Table Table, Figure n Table3.Survival rates according to sexn 779 Sex Male Femal Cases n 59 n 5 Y 8. 9 Y Y Y Y Of the 738, 59 cases were excluded in which sex and/or c-stage articles were not available, and survival rates of 779 cases were calculated Table.Number of cases according to sex and clinical stagen 779 c-stage A B A B A B Unknown Total Male Female Total Of the 738, 59 cases were excluded in which sex and/or c-stage articles were not available, and 779 cases were analyzed Japanese Journal of Lung CancerVol, No 6, Oct, 557

4 Figure Survival rates according to sex n779 Figure 3 Survival rates according to c-stage n768 survival probability Female n=5 Male n= years survival probability.6 IB IIA IIIA years IA IIB IIIB IV 3 5 Table5.Suvival rates accordng to c-stagen 768 c-stage A B A B A B Total Cases Y Y Y Y Y Of the 738 cases, there were cases in which the c-stage was not available; cases in which the c- STAGE= amounted to cases; and those in which the c-stage was unknown amounted to 8 cases. These 7 cases were excluded and the survival rates according to c-stage were calculated in 768 cases Table6.Survival rates according to p-stagen 77 p-stage A B A B A B Total Cases Y Y Y Y Y Of the 738 cases, p-stage not available was 7 cases; p-stage=, 9 cases; p-stage unknown, 35 cases, totaling 9 cases. These cases were excluded, and the survival rates according to p-stage were calculated in 77 cases Japanese Journal of Lung CancerVol, No 6, Oct,

5 Figure Survival rates according to p-stage n77 Table7.Histological distribution survival probability.6 IV IIIB IB IIA IIIA IA IIB Histologic type Adenocarcinoma Squamous cell carcinoma Large cell carcinoma Small cell carcinoma Adenosquamous cell carcinoma Carcinoid Adenoid cystic carcinoma Cases years 3 5 Mucoepidermoid carcinoma Others 9 33 Default 8 Total The cases were classified according to histological type. Figure 5 Survival rates according to histological type survival probability.6 Adenoca.n=6 Squamouscell ca.n= Largecellca.n=66 Smallcellca.n=8 Adenosquamousca.n=85 years 3 5 n5 5 6 Table 3 Table Figure c-stage Table 5 Figure 3 5 c-stage IAn687.5 c-stage IBn665c-STAGE IIAn69 7.8c-STAGE IIBn793c-STAGE IIIA n3853.6c-stage IIIBn3957.6c- STAGE IVn69.9 p-stage Table 6 Figure 5 p-stage IAn79. p-stage IBn886p-STAGE IIAn6 58.6p-STAGE IIBn785.p-STAGE IIIA n3378.p-stage IIIBn759p- STAGE IVn759.3 Table 7 Figure Figure Japanese Journal of Lung CancerVol, No 6, Oct, 559

6 Figure 6 Survival rates according to left or right lung n785 survival probability years 3 Right n= 5y-Survival 5.8 Left n=963 5y-Survival5.9 Of the 738 cases, laterality not available amounted to 6 cases; unknown, 9 cases; others, 8 cases; totaling 53 cases. These cases were excluded, and the survival rates according to laterality were calculated in 785 cases. 5 3 MountainChest. 997; : Mountain CT Mountain c-stage IA 5 Mountain p-stage IA 5 Mountain STAGE IB STAGE IIA TNM staging 989 UICC-TNM STAGE I STAGE II STAGE IIIA, IIIB JA JR 56 Japanese Journal of Lung CancerVol, No 6, Oct,

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12 5. ptnmt 7. ptnmm T 3 M T M T T T 77 Tis TX p-stage p-stage p-stage 3 6. ptnmn A B A N 6 6 B 8 N A N 66.9 B N NX # # #3 #3a #3p # #5#6#7#8#9### # # #3 #3a #3p # #5 # #7 #8 #9 # # # Japanese Journal of Lung CancerVol, No 6, Oct,

Table 1. Numbers of Cancerous Pleurisy Cases According to Primary Site Table 2. Histological Type of Lung Carcinoma with Cancerous Pleurisy at Autopsy

Clinicopathological Studies on Cancerous Pleurisy, with Emphasis on Extra-Pulmonary Malignancy Table 1. Numbers of Cancerous Pleurisy Cases According to Primary Site Table 2. Histological Type of Lung