EHS EHS 197 EHS 215 EHS P.4 2EHS 49% 214 CO2 3 GHG CO2 -CO2 6 3 417 CO23 -CO2 75 15 1 13 14 13 14 13 14 13 14 13 14 144 1 23 1 29 32 46 7.5 215 5 1 11 12 13 14 15 CO2 CO2 CO2 214 CO2GHG m 3 1, 5, 6,161 4,89 1 11 12 13 14 P.46 P.48 38 Takeda CSR Data Book 215
KEY FIGURES 19% 2% 214 CO2 25 214 21 18% 214 PRTR 21 127 214 22 22CO2 NOxSOx CO22525% 22 CO2 25 25% 22 25 2% NOx 75% SOx 6% 3% FUTURE OUTLOOK 3 22 EHS P.88 Takeda CSR Data Book 215 39
EHS 197 Takeda Environment Action Tree 212 Global One TakedaEHS EHS EHS 215 EHS 23 TEA Tree Message Patient TrustReputation Business E H S EHS EHS EHS215 CO2222525% Shinji Honda 4 Takeda CSR Data Book 215
EHS 3 EHS EHS EHS 213EHS 214 EHS EHS EHS 214EHS Takeda CSR Data Book 215 41
21 21522 P.58 212LIME 1 3 15 5 6 7 8 CO2 SOx 5-14 12-14 LIME 1 LIMELife-cycle Impact assessment Method based on Endpoint modeling 9 1 11 12 13 14 9 12 13 14 1,8 Message & EHS 215 Safe Takeda GMSO Thomas Wozniewski 42 Takeda CSR Data Book 215
1995 3 2 9, 949 1,531 123 166 7 963 Co., Ltd. Pvt. Ltd. S.p.A. GmbH GmbH Pharma Ltda.ISO141 25 1,171 21441215331 25 39 51 3,199 ISO141 Co., Ltd. Pvt. Ltd. S.p.A. GmbH GmbH Pharma Ltda. 12 2 CDP2141 96 18 2151 5432 SNAM SRI 198 214 1232 Takeda CSR Data Book 215 43
EHS 16 214 EHS EHS 213EHS 214 67 214EHS Process Mass IntensityPMI 1 CMC PMI 2 1 1kg 2 Inc. S.p.A. Pvt. Ltd. AS Pharma Sp.z o.o. Pharma Ltda. Pharma S.A. 44 Takeda CSR Data Book 215
Takeda s Voice 22 Pharma Ltda. 214 215 Pharma Ltda. Luiz Antonio da Rocha Takeda CSR Data Book 215 45
CO21974 CO2 -CO2 6 516 1974 4 399 44 418 417 423 387 3 262 CDP 1 1 CDP 19% 214 CO2 25 CO2215 2518 22 CO2 CO222 2525 CO2215 1993% CO222 1994% 214 2131511 214 CO227199 35% 214CO2421 16.4225.425 19% 5 1 11 12 13 14 15 2 CIS P.38 CO2 214 421kWh 2136 CO2 46 Takeda CSR Data Book 215
214 S.p.A. GmbH Pvt. Ltd. CII 214 211 28 1% 214 68% CO2 21 1 CO2 49% 214 CO2 3 GHG 212 12 3 CO2 P.38 CO23 CO2 214 2% 4% 2% 1-CO2 1 6% 29-CO2 9% 46-CO2 27% 144-CO2 3 49% 1 19% 2 32% 1: 2: 3: P.88 Takeda CSR Data Book 215 47
7 G l o b a l Water Tool 1 3 1 WBCSD 22 25 3 1 A B A C B C m 3 1, 5, 6,161 4,89 1 11 12 13 14 212WET 2 P.88 2 WETWhole Effluent Toxicity 48 Takeda CSR Data Book 215
2.2% 214 127 214 212 213 214 2.3% 2.3% 2.2% 19392 1996 1212 1933 8 2,82,214 12715 2175 3 26 P.54 http://www.takeda.co.jp/kyoto/ Takeda CSR Data Book 215 49
5 Takeda CSR Data Book 215 1993 211215 21 5 214 222153% 35 212% 29 5 12 11 1 5 25 14 13 44 35 1.9 25,643 35 12,869 17,362 22 27 54 7,475 6,936 458 5,533 539 2,685 255 2,43 8,218 1,385 214 21 211 212 213 2,855 5,333 9,97 69 399 873 1,448 585 22,153 3,175 4,7 9,843 777 582 837 1,424 744 22,83 5,164 5,851 8,818 757 376 784 1,49 816 23,975 3,729 6,573 1,459 661 355 787 1,388 744 24,697 214 3,255 7,77 1,727 817 365 765 1,276 732 25,643 2% 214 21
PRTR 6, 4,949 18% 21 214 PRTR 21 PCB 3, 1 11 12 13 1,186 41 14 SDS OEL WET PRTR 214PRTR 1112 2%2572% 215257% 6341 42118% 214VOC 211 214 PRTR 15.9 15.9 168 168 11.7 11.7 2 267 267 1,2-6.5 6.5 4. 4. 2.1 2.1 1 426 426.7 1.4 2. 1.4 1.4 2 5 5 1 P.88 Takeda CSR Data Book 215 51
SOxNOx 4 SOx NOx 2 94 1 11 12 13 14 14 4 2 1 11 12 13 2 14 COD 6 48 NOxSOx 3 COD 214 NOxSOx 1 11 45921 12 13 14 NOxSOx 22NOxSOx NOx22252% 214 SOx222575% 52 Takeda CSR Data Book 215
2154 Inc. Inc.TCAL 2152 2,15TCAL214 2 1 CSR 214 Takeda CSR Data Book 215 53
2149 2124 26 211 5 2,5 2158 1 26 54 Takeda CSR Data Book 215
8,387 MJ 216,381 kl 521,94 MWh 3,369 kl 595 kl 65,215 m 3 3,211 m 3 2,389 m 3 49 m 3 64 m 3 7 m 3 PRTR PRTR 4,949 7,624 13,81 CO2 SOx NOx PRTR VOC C O D PRTR 417 -CO2 14 94 2 4 211 1.5 4,89 m 3 21 1.4 35,69 1,917 25,724 4,688 CO2 3,74 -CO2 23,81 2 CO2 5,883 -CO2 2 CO2 21441215331 CO2PRTR 1 VOCVOC1n-11 P.88 Takeda CSR Data Book 215 55
MJ 21 211 212 213 214 4,938 5,654 6,69 5,947 5,63 CIS 372 1,988 1,717 1,718 1,717 273 369 366 386 634 637 657 693 681 5,944 8,553 8,811 8,725 8,387 CO2 21 211 212 213 214 21,174 276,81 31,79 325,38 319,88 CIS 17,427 81,936 5,949 5,3 54,992 6,159 8,846 8,31 7,955 34,993 34,929 33,559 35,134 34,665 262,594 399,16 44,144 418,476 417,492 m 3 21 211 212 213 214 5,716 6,13 6,19 5,658 5,132 CIS 62 826 681 712 79 18 21 164 176 125 13 12 139 143 5,93 7,15 7,29 6,673 6,161 SOx 21 211 212 213 214 29 21 9 13 4 CIS.3 67 1 92 1.7.6.4.5 2 4 3 3 4 29 89 11 16 14 56 Takeda CSR Data Book 215
NOx 21 211 212 213 214 183 25 229 227 6 CIS 11 53 65 68 28.5 4 3 3 1 2 1 1 3 195 26 3 3 94 21 211 212 213 214 22,29 22,77 24,239 25,839 26,818 CIS 1,994 11,539 13,289 14,142 15,212 829 1,27 1,251 1,224 571 63 773 77 74 24,773 35,75 39,58 42,2 43,957 21 211 212 213 214 2 13 7 5 4.1.1 11 22 16 18 331 369 282 233 282 351 392 311 254 35 PRTR 21 211 212 213 214.9.5.2.2.2 11.1 16.6 14.8 11.3 11.7.5.8.7.5 36.5 39.1 18.3 22.2 27.2 48.5 56.6 34. 34.4 39.6 Takeda CSR Data Book 215 57
214 214 T-EMS ISO141 EHS Pvt. Ltd. 3ISO141 CO2215 2518% 214CO241.7 2519% 215 S.p.A. 21521 21435 212% ReduceReuse Recycle3R RO PCB PCB 58 Takeda CSR Data Book 215
214 NOxSOx COD 122 93 ABS Message EHS 22CO2 56-57 5 SOxNOx21452 2525 Takashi Fukushima Takeda CSR Data Book 215 59