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2005 10 13 Dr. RGA

19602000 10 Australian Institute of of Health and and Welfare 2004 ABS Cat. Cat. No. No. 3201.0; AIHW National Population Database

1875 2 211997 8 122164 http://www.wowzone.com/calment.htm http://www.recordholders.org/en/list/oldest.html

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10010020 Picture from National Centre for Biotechnology Information Genes and Disease

DNA

. Deaths per Year 106,000 80,000 45,000 12,000 7,000 250,000 Cause

Cancer Statistics in Japan 2003

Cancer Statistics in Japan 2003

- -

1988 1993 1998 2003

mmhg mmhg Chobanian, AV et al. JAMA. May 21, 2003 Vol. 289 No. 19, pg 2560-2571

Table. 95 HERS + WHI + WHI Table from Hulley SB et al, JAMA. 2004;291:1769-1771

70 60 50 40 30 20 10 0 India Ghana China Philippines Japan Morocco Tunisia Togo Mauritius Kyrgyzstan Seychelles Malaysia Hong Kong Norway France Italy Netherlands Switzerland Sweden Brazil Denmark Austria Turkey South Africa Mexico Spain Belgium Canada New Zealand Kuwait Hungary Uruguay Germany United Saudi Arabia Australia Neth Antilles United Finland Jordan Samoa % Men Women U S A Swinburn B et al. WHO (2001) www.heartstats.org

Samoa Kuwait United Kingdom New Zealand Mauritius United States Australia Germany Switzerland Netherlands Brazil Finland South Africa Sweden Canada China Japan France India Italy Malaysia -0.20 0.00 0.20 0.40 0.60 0.80 1.00 1.20 1.40 1.60 Average % increase per annum Swinburn B et al. WHO (2001) www.heartstats.org

Source - JAMA. 2003;289:76-79

65 Figure from Olshansky, SJ et al, NEJM, March 17,2005;352 (11):1138

65 1981 1984 1995 1980-2000 Figure from Olshansky, SJ et al, NEJM, March 17,2005;352 (11):1138

X 16-35 100 400,000 100 36-40 100 200,000 750,000 41-45 500,000 200,000 500,000 2 M 2 M 46-50 500,000 200,000 350,000 2 M 2 M 51-55 500,000 200,000 250,000 1 M 1 M 56-60 250,000 200,000 100,000 1 M 1 M 61+ 100,000 200,000 50,000 500,000 500,000 US

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CHD BMI 10 Source: Rexrode KM, et al, JAMA 1998;280:1843-1848

1 150mg/dl(1-7mmol/L) HDL 40mg/dl(1-03mmol/L) 50mg/dl(1-23mmol/L) 130mmH 85mmHg Lancet, Sept 24 2005;366;1059-62 100mg/dL(5-6mmol/L) 5.6mmol/L 100mg/dL

TABLE 2. N 95 N 95 0 695 10.8 1 645 10.8 1 1 2077 32.2 1.79 1.11, 2.89 * 1932 32.3 2.36 0.71, 7.93 2 1984 30.8 2.25 1.40, 3.60 ** 1819 30.5 4.50 1.39, 14.6 * 3 1339 20.8 3.19 1.98, 5.12 ** 1256 21.0 7.26 2.25, 23.4 ** 4 352 5.4 3.65 2.11, 6.33 ** 322 5.4 24.4 7.53, 79.6 ** *P 0.05 **P 0.01

C-CRP) Figure from Sattar N et al. Circulation July 2003;108:414-419

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Pell 58 Pell JP, BMJ. 2003 January 18; 326 (7381): 134 135

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697 246 (35.3%) 21 (3.0%) : 80% 100% : 91.7% 33.3% Lee HK et al, Yonsei Med J. 2003 Dec 30;44(6):1040-4

Breslow 1.5mmClark 3 TNMT1a T1b 1cmT1N0M0 RAI3 HIV 41

30%-50% have not had a mammogram in past 2 years 27% of women over the age of 65 have never had a PAP smear screen for cervical cancer 70% of at risk public not getting colon cancer screening

47

PSA Figure from Oliver SE el al, Lancet 2000 May 20;355(9217):1788-9

PSA 1/3 NMP48 PSA

St. Jude s Children s Research Hospital Cancer Survival Rates 51

: HIV :

SARS O157 O157 C HIV Figure from Morens, DM et al, Nature. 2004 Jul 8;430(6996):242-9

A (H5N1) A 1961

WHO 28 A(H5N1) : 2003 12 26 2004 3 10 0 0 23 16 12 8 0 0 35 24 2004 7 19 2004 10 8 0 0 4 4 5 4 0 0 9 8 2004 12 16 4 3 64 21 0 0 4 4 71 28 : 4 3 91 41 17 12 4 4 116 60 WHO Communicable Disease Surveillance & Response (CSR), September 29, 2005

H5N1 H5N1 (oseltamavir zanamavir) H5N1

1918, 105,000,000 500,000 0.5 1957, 170,000,000 70,000 0.04% ICU ( 58% )

1918 Source: http://www.cdc.gov/ncidod/eid/vol3no4/lederber.htm

???? 200 700 25% 0.37-2.5%. 400. 15,000 100,000400X0.37 2.5???

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