Contents 1. 2 2. 3 3. 7 4. 9 5. 14 6. 15 7. 17 8. 19 9. 21
1. growth hormone deficiency : GHD10,00015,000 2
2. 03 1GH T3T4 1 GHRHGHIH -CIGF-1 -CIGF-1 3
1 GHRH GHIH GH TSH LHFSH -C IGF-1 -C IGF-1 T3T4 4
23 8 5
2 3 9 15 3 6
3. 1 SD2 1. 2SD 2. 1 1.5SD2 1 2SD 1 1 1.5SD1 22SD 7
8 11.3 8.8 7.5 6.8 6.3 6.0 5.8 5.6 5.4 5.2 5.1 4.9 4.6 4.4 4.3 4.1 4.2 4.4 5.2 6.0 6.7 6.1 4.5 2.9 1.7 1.1 0.6 0.4 0.2 0.0 0.0 0.0 0.0 11.6 8.9 7.6 7.0 6.4 6.0 5.8 5.4 5.1 4.9 4.6 4.5 4.6 4.5 4.4 4.3 4.1 4.0 3.9 4.0 4.1 4.5 5.5 6.9 7.7 6.9 5.0 3.3 2.3 1.4 0.8 0.3 0.0 0.0 44.2 61.6 68.4 73.9 78.4 82.1 85.5 88.8 91.9 94.8 97.7 100.6 103.4 106.1 108.8 111.4 113.9 116.4 118.8 121.2 123.9 126.7 130.2 133.8 137.0 140.2 142.3 144.3 145.3 146.2 146.5 146.9 147.1 147.2 147.4 147.6 48.4 66.2 73.4 79.4 84.3 88.4 92.2 95.9 99.5 102.8 106.2 109.5 112.7 115.8 118.8 121.7 124.6 127.5 130.5 133.5 136.9 140.3 143.7 147.1 149.6 152.1 153.6 155.1 156.0 156.8 157.1 157.3 157.5 157.7 157.9 158.1 44.7 63.1 69.8 74.9 79.4 83.1 86.4 89.5 92.5 95.3 98.1 100.9 103.8 106.8 109.5 112.2 114.7 117.2 119.7 122.1 124.5 126.8 128.9 131.0 133.9 136.8 140.7 144.6 148.6 152.5 154.7 156.8 157.7 158.5 158.8 159.1 43.2 60.5 67.1 72.5 77.0 80.5 83.8 87.0 90.0 92.8 95.6 98.4 101.1 103.6 106.3 108.9 111.2 113.6 115.8 118.1 120.7 123.3 126.9 130.4 133.9 137.3 139.4 141.6 142.6 143.6 143.9 144.3 144.4 144.6 144.8 145.0 43.6 61.9 68.5 73.5 77.9 81.5 84.7 87.7 90.5 93.2 95.9 98.6 101.4 104.3 107.0 109.7 112.1 114.5 116.9 119.3 121.5 123.8 125.6 127.5 130.1 132.8 136.8 140.8 145.0 149.3 151.6 153.9 154.8 155.6 155.9 156.2 49.0 67.8 75.0 80.5 85.4 89.6 93.3 96.9 100.2 103.5 106.7 110.0 113.3 116.7 119.6 122.5 125.3 128.1 130.9 133.6 136.4 139.1 142.2 145.3 149.1 152.9 156.5 160.0 162.8 165.5 167.1 168.6 169.4 170.1 170.5 170.8 00 06 10 16 20 26 30 36 40 46 50 56 60 66 70 76 80 86 90 96 100 106 110 116 120 126 130 136 140 146 150 156 160 166 170 176 1212 Suwa, S et al : Clin Pediatr Endocrinol 1992, 11, 5-13 1 1 cm -2SD cm cm -2SD cm -2.5SD cm -2.5SD cm -1.5SD cm/ -1.5SD cm/
4. 14.0cm 2SD 9
X X -C 10
MRICT 1 1 30 5 30120 10% 3030 120 11
L-DOPA L-DOPA 30120 30120 30 180 2 10ng/mL 12
4 1. 10ng/mL 2. 510ng/mL 3. 5ng/mL 4. 21 223 4 4 ng/ml 30 20 10 0 0 30 60 90 120 1715 2SD 11.5SD 2 230 10ng/mL 13
5. 5 5 14
6. 124 15
16
7. 1 1 2 3 4 5 6 7 6.0cm1 12.0cm 2.0cm 2.0cm 1.8cm 1.4cm 1.2cm 1.0cm 1715 18 17
2.5SD 1 6.0cm 2.0cm 2 3cm 156.4cm145.4cm 18
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9. X 8 10001 21
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