1
99.2 10 98.5 10 15 95 20 2
24 U1RNP 140 90 3
100 20 25 4
5
WHO 6
10 20 10 10 15 7
10 1990 2000 2009 WHO 20 1990 8
11 0.002 10 10 20 10 12 9
13 MCTD 10 20 60 10
14 10 40 / 11
15 16 %VC FEV 1 COPD DLCO DLCO 12
BNP NT-proBNP 17 SCLERODERMA FOUNDATION 13
18 25 14
19 20 10 2002 WHO 2010 1999 60 30 24 15
20 21 1999 2005 2008 16
- 22 17
23 23 DNA 23 18
3 24 WHO 54 34 21 20 19
25 20
26 40 21
27 22