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ASCO DAILY NEWS MONDAY JUNE 7, 2010 THE OFFICIAL DAILY NEWSPAPER OF THE ASCO ANNUAL MEETING INSIDE THIS SECTION Gynecologic Cancer Patient and Survivor Care 2010 ANNUAL MEETING CHICAGO, IL ISSUE 3 SECTION A Central Nervous System Tumors Gastrointestinal (Colorectal) Cancer Genitourinary (Prostate) Cancer Lung Cancer Local-regional and Adjuvant Therapy Lymphoma Melanoma/Skin Cancers Special Sessions In Briefs Late-breaking and Clinical Review Abstracts Translation of ASCO Daily News Monday, June 7, 2010 ISSUE 3 Chicago, IL Section A 2010 American Society of Clinical Oncology. All rights reserved.

2A ASCO Daily News MONDAY, JUNE 7, 2010 RESULTS N (%) CR PR SD PD Response rate CR+PR [95% CI] Control rate CR+PR+SD [95% CI] 1 (3%) 3 (8%) 21 (58%) 11 (5 non evaluable) (31%) 11% [3-26] 69% [52-84] RESULTS N (%) CR PR SD PD Response rate CR+PR [95% CI] Control rate CR+PR+SD [95% CI] 2 (6%) 8 (22%) 15 (42%) 11 (5 non evaluable) (31%) 28% [14-45] 69% [52-84] ASCO Daily News The Official Newspaper of the 2010 ASCO Annual Meeting Vol. 13, No. 3 Monday, June 7 ASCO Daily News, the official newspaper of the 2010 ASCO Annual Meeting, is published by the American Society of Clinical Oncology as a service to all who attend. American Society of Clinical Oncology 2009-2010 Officers Douglas W. Blayney, MD President ASCO Daily News Monica Morrow, MD Editor in Chief John Sweetenham, MD Associate Editor Andrea Smiley Managing Editor Lisa Greaves Publisher Alex Castellino, PhD Catherine Dold Tim Donald, ELS Peggy Farrell Jennifer Koenig David Levitan Walter Jones Kara Nyberg, PhD KT Porter Melinda Tanzola Section A Writers ASCO Daily News Japanese Edition ASCO Daily News Nagahiro Saijo, MD, PhD Professor, Kinki University School of Medicine Executive Advisor Noriyuki Katsumata, MD (ISSUE 1) Yutaka Fujiwara, MD, PhD (ISSUE 2) Naruo Yoshimura, MD, PhD (ISSUE 3) Scientific Advisors Karen M. Mustian, PhD, MPH Medical News & Conference Systems, Inc. 8F Towahoridomecho Bldg., 2-1-1, Nihonbashi Horidomecho, Chuo-ku, Tokyo, Japan, 103-0012 TEL: +81-3-5652-3500 FAX: +81-3-5652-3503 URL: http://www.mncs.co.jp Publisher Shin Yoshimoto Director of Publication Akira Miyakawa, MD Editor in Chief Hiromi Harada Zlatina Zlateva, MD Japanese Translation & Editing Masahiro Matsumoto Coordinator & Advertising Translation of selected articles from the ASCO Daily News. Copyright American Society of Clinical Oncology 2010. All rights reserved. The authors, editors, and ASCO are not responsible for errors or omissions in translations. The views expressed in ASCO Daily News do not necessarily reflect those of the American Society of Clinical Oncology (ASCO). The information contained in this publication is provided solely for educational purposes. A diversity of opinions exists in the field of oncology, and the articles in this publication are often intended to inform readers about more than one point of view. These articles are not comprehensive, and should not be used as a substitute for traditional sources of scientific information and the individual judgment of health care providers. ASCO is not responsible for misuse of the information, publications or services discussed or advertised within. ASCO Daily News ASCO Daily News

4A ASCO Daily News MONDAY, JUNE 7, 2010 ORR % (x/n) Ovarian 41.2 (7/17) Breast 0 (0/8) * BRCA 95% confidence interval* (%) ORR % (x/n) 21.6, 64.0 23.9 (11/46) 0, 32.4 0 (0/15) Non-BRCA 95% confidence interval (%) 13.9, 37.9 0, 20.4

6A ASCO Daily News MONDAY, JUNE 7, 2010

8A ASCO Daily News MONDAY, JUNE 7, 2010 VIEW THE DAILY NEWS VIDEO CLIP OF THE DAY Download the ScanLife application to your mobile device and scan this barcode with the ScanLife app. Download one of two ways: 1. Go to www.getscanlife.com from your phone s mobile browser, or 2. Text SCAN to 43588

10A ASCO Daily News MONDAY, JUNE 7, 2010 Daniel D. Von Hoff, MD

MONDAY, JUNE 7, 2010 ASCO Daily News 11A

The 48th Annual Meeting of the Japan Society of Clinical Oncology

MONDAY, JUNE 7, 2010 ASCO Daily News 15A